Search filters

List of works by Jon H Chung

A Combination of Targeted Therapy with Chemotherapy Backbone Induces Response in a Treatment-Resistant Triple-Negative MCL1-Amplified Metastatic Breast Cancer Patient.

scientific article published on January 2016

A PTCH1 homolog transcriptionally activated by p53 suppresses Hedgehog signaling

scientific article

A Poorly Differentiated Malignant Neoplasm Lacking Lung Markers Harbors an EML4-ALK Rearrangement and Responds to Crizotinib

scientific article

A loss-of-function mutation in PTCH1 suggests a role for autocrine hedgehog signaling in colorectal tumorigenesis.

scientific article published on December 2013

Acquired FGFR and FGF alterations confer resistance to estrogen receptor (ER) targeted therapy in ER+ metastatic breast cancer

scientific article published on 28 July 2020

Analytical Validation of a Hybrid Capture-Based Next-Generation Sequencing Clinical Assay for Genomic Profiling of Cell-Free Circulating Tumor DNA

scientific article published on 22 June 2018

Arabidopsis thaliana expresses multiple Golgi-localised nucleotide-sugar transporters related to GONST1.

scientific article published on 8 October 2004

BRCA2 Reversion Mutation Associated With Acquired Resistance to Olaparib in Estrogen Receptor-positive Breast Cancer Detected by Genomic Profiling of Tissue and Liquid Biopsy

scientific article published on 21 December 2017

Cdk2 is required for p53-independent G2/M checkpoint control

scientific article

Characterization of Clinical Cases of Advanced Papillary Renal Cell Carcinoma via Comprehensive Genomic Profiling

scientific article

Chk1 suppresses bypass of mitosis and tetraploidization in p53-deficient cancer cells

scientific article published on 15 April 2012

Comprehensive genomic profiling of anal squamous cell carcinoma reveals distinct genomically defined classes

scientific article published on 6 April 2016

Comprehensive genomic profiling of malignant phyllodes tumors of the breast.

scientific article published on 17 February 2017

Exceptional response to olaparib in BRCA2-altered urothelial carcinoma after PD-L1 inhibitor and chemotherapy failure

scientific article published on 18 April 2018

Genomic Characterization of Testicular Germ Cell Tumors Relapsing After Chemotherapy

scientific article published on 17 July 2018

Genomic Profiling of Parathyroid Carcinoma Reveals Genomic Alterations Suggesting Benefit from Therapy

scientific article published on 29 October 2018

HER2 Transmembrane Domain (TMD) Mutations (V659/G660) That Stabilize Homo- and Heterodimerization Are Rare Oncogenic Drivers in Lung Adenocarcinoma That Respond to Afatinib.

scientific article published on 26 November 2016

Hybrid capture-based genomic profiling of circulating tumor DNA from patients with advanced cancers of the gastrointestinal tract or anus.

scientific article published on 23 January 2018

Hybrid capture-based genomic profiling of circulating tumor DNA from patients with estrogen receptor-positive metastatic breast cancer.

scientific article

Identification of Targetable ALK Rearrangements in Pancreatic Ductal Adenocarcinoma

scientific article published in May 2017

Multiparametric Magnetic Resonance Imaging as a Noninvasive Assessment of Tumor Response to Neoadjuvant Pembrolizumab in Muscle-invasive Bladder Cancer: Preliminary Findings from the PURE-01 Study

scientific article published on 24 December 2019

Pan-Cancer Analysis of CDK12 Loss-of-Function Alterations and Their Association with the Focal Tandem-Duplicator Phenotype

scientific article published on 10 July 2019

Pembrolizumab as Neoadjuvant Therapy Before Radical Cystectomy in Patients With Muscle-Invasive Urothelial Bladder Carcinoma (PURE-01): An Open-Label, Single-Arm, Phase II Study

scientific article published on 20 October 2018

Predicting the pathologic complete response after neoadjuvant pembrolizumab in muscle-invasive bladder cancer

scientific article published on 09 June 2020

RET rearrangements are actionable alterations in breast cancer

scientific article published in Nature Communications

Recurrent hyperactive ESR1 fusion proteins in endocrine therapy resistant breast cancer.

scientific article published on 19 January 2018

Repurposing the antihelmintic mebendazole as a hedgehog inhibitor.

scientific article

Responses to Alectinib in ALK-rearranged Papillary Renal Cell Carcinoma

scientific article published on 01 July 2018

Unfavorable Cancer-specific Survival After Neoadjuvant Chemotherapy and Radical Cystectomy in Patients With Bladder Cancer and Squamous Cell Variant: A Multi-institutional Study

scientific article published on 08 February 2020

Updated Results of PURE-01 with Preliminary Activity of Neoadjuvant Pembrolizumab in Patients with Muscle-invasive Bladder Carcinoma with Variant Histologies

scientific article published on 08 November 2019

Paulina is supported by:

About Paulina

Help