List of works - Mei-Kwan Yau

Benzylamide antagonists of protease activated receptor 2 with anti-inflammatory activity.

scientific article published on 17 December 2015

Diet-induced obesity, adipose inflammation, and metabolic dysfunction correlating with PAR2 expression are attenuated by PAR2 antagonism

scientific article

Downsizing a human inflammatory protein to a small molecule with equal potency and functionality.

scientific article

Efficient chemical synthesis of human complement protein C3a

scientific article

Mapping transmembrane residues of proteinase activated receptor 2 (PAR2) that influence ligand-modulated calcium signaling.

scientific article

PAR2 Modulators Derived from GB88.

scientific article

Pathway-selective antagonism of proteinase activated receptor 2.

scientific article

Potent Small Agonists of Protease Activated Receptor 2.

scientific article published on 30 November 2015

Potent complement C3a receptor agonists derived from oxazole amino acids: Structure-activity relationships.

scientific article published on 23 October 2015

Potent heterocyclic ligands for human complement c3a receptor

scientific article published on 8 October 2014

Programmable multistage drug delivery to lymph nodes

scientific article published on 10 June 2020

Protease activated receptor 2 (PAR2) modulators: a patent review (2010-2015).

scientific article published on 3 March 2016

Publisher Correction: Programmable multistage drug delivery to lymph nodes

scientific article published on 06 July 2020

Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists.

scientific article

Repurposing Registered Drugs as Antagonists for Protease-Activated Receptor 2.

scientific article published on 7 October 2015

Stereoelectronic effects dictate molecular conformation and biological function of heterocyclic amides.

scientific article

Structure, function and pathophysiology of protease activated receptors.

scientific article published on 26 January 2011

Three Homology Models of PAR2 Derived from Different Templates: Application to Antagonist Discovery.

scientific article published on 22 May 2015

List of works by Mei-Kwan Yau

Benzylamide antagonists of protease activated receptor 2 with anti-inflammatory activity.

Diet-induced obesity, adipose inflammation, and metabolic dysfunction correlating with PAR2 expression are attenuated by PAR2 antagonism

Downsizing a human inflammatory protein to a small molecule with equal potency and functionality.

Efficient chemical synthesis of human complement protein C3a

Mapping transmembrane residues of proteinase activated receptor 2 (PAR2) that influence ligand-modulated calcium signaling.

PAR2 Modulators Derived from GB88.

Pathway-selective antagonism of proteinase activated receptor 2.

Potent Small Agonists of Protease Activated Receptor 2.

Potent complement C3a receptor agonists derived from oxazole amino acids: Structure-activity relationships.

Potent heterocyclic ligands for human complement c3a receptor

Programmable multistage drug delivery to lymph nodes

Protease activated receptor 2 (PAR2) modulators: a patent review (2010-2015).

Publisher Correction: Programmable multistage drug delivery to lymph nodes

Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists.

Repurposing Registered Drugs as Antagonists for Protease-Activated Receptor 2.

Stereoelectronic effects dictate molecular conformation and biological function of heterocyclic amides.

Structure, function and pathophysiology of protease activated receptors.

Three Homology Models of PAR2 Derived from Different Templates: Application to Antagonist Discovery.