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List of works by Christos M. Hatzis

A 50-year follow-up of the Seven Countries Study: Prevalence of cardiovascular risk factors, food and nutrient intakes among Cretans

scientific article

A genome-wide approach to link genotype to clinical outcome by utilizing next generation sequencing and gene chip data of 6,697 breast cancer patients.

scientific article

A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer.

scientific article

A statistical analysis of flow cytometric determinations of phagocytosis rates

scientific article published on January 1, 1992

Adherence to the Mediterranean Diet in Relation to Obesity Indices before and after a Weight Reduction Program in OSAS Patients

scientific article published on October 2014

Adipose tissue fatty acid composition in Greek patients with breast cancer versus those with benign breast tumors

Ambient particulate matter exhibits direct inhibitory effects on oxidative stress enzymes

scientific article published on April 2006

An integrative bioinformatics approach reveals coding and non-coding gene variants associated with gene expression profiles and outcome in breast cancer molecular subtypes

scientific article published on 21 March 2018

Analysis and modeling of growing budding yeast populations at the single cell level

scientific article published on February 2009

Analysis of Pre- and Posttreatment Tissues from the SWOG S0800 Trial Reveals an Effect of Neoadjuvant Chemotherapy on the Breast Cancer Genome

scientific article published on 09 January 2020

Annual Review of Biophysics

scientific article published on July 2013

Assessing cost-utility of predictive biomarkers in oncology: a streamlined approach

scientific article published on 9 January 2016

Assessing the Nutritional Status of Palestinian Adolescents from East Jerusalem: a School-based Study 2002-03 ⬇️

scientific article published on July 31, 2010

Assessment of pharmacogenomic agreement

scientific article

Association Between Genomic Metrics and Immune Infiltration in Triple-Negative Breast Cancer

scientific article

Association of LN Evaluation with Survival in Women Aged 70 Years or Older With Clinically Node-Negative Hormone Receptor Positive Breast Cancer

scientific article

Association of T-Cell Receptor Repertoire Use With Response to Combined Trastuzumab-Lapatinib Treatment of HER2-Positive Breast Cancer: Secondary Analysis of the NeoALTTO Randomized Clinical Trial

Association of adipose tissue arachidonic acid content with BMI and overweight status in children from Cyprus and Crete

scientific article published in April 2004

Atherogenic risk factors among preschool children in Crete, Greece ⬇️

scientific article published on September 1, 2012

Biochemical engineering analysis of critical process factors in the biomass-to-ethanol technology.

scientific article published in May 1997

Bioprocessing research

scientific article published on 01 January 1997

Breast Cancer Heterogeneity Investigation: Multiple k-Means Clustering Approach

scientific article published in October 2019

Breast cancer patients with brain metastasis undergoing GKRS

scientific article published on 04 September 2018

Calcium, nutrient and food intake of Greek Orthodox Christian monks during a fasting and non-fasting week

scientific article

Cardiovascular disease risk factors and dietary habits of farmers from Crete 45 years after the first description of the Mediterranean diet

scientific article published in August 2010

Characterization of DNA variants in the human kinome in breast cancer

scientific article

Chemotherapy for Elderly Ovarian Cancer Patients

scientific article published on 31 August 2016

Co-targeting the HER and IGF/insulin receptor axis in breast cancer, with triple targeting with endocrine therapy for hormone-sensitive disease

scientific article published on 24 February 2017

Combinatorial Screening of Pancreatic Adenocarcinoma Reveals Sensitivity to Drug Combinations Including Bromodomain Inhibitor Plus Neddylation Inhibitor

scientific article published on 14 March 2017

Combined analysis of gene expression, DNA copy number, and mutation profiling data to display biological process anomalies in individual breast cancers.

scientific article

Commercialized multigene predictors of clinical outcome for breast cancer.

scientific article

Common contaminants in next-generation sequencing that hinder discovery of low-abundance microbes

scientific article

Comparison of Residual Risk-Based Eligibility vs Tumor Size and Nodal Status for Power Estimates in Adjuvant Trials of Breast Cancer Therapies

scientific article published on 25 January 2018

CtIP silencing as a novel mechanism of tamoxifen resistance in breast cancer

scientific article published on December 2007

Depression and serum adiponectin and adipose omega-3 and omega-6 fatty acids in adolescents

scientific article published on 01 October 2006

Development of an epi-fluorescence assay for monitoring yeast viability and pretreatment hydrolysate toxicity in the presence of lignocellulosic solids

scientific article published on 01 January 1996

Development of candidate genomic markers to select breast cancer patients for dasatinib therapy

scientific article

Dietary and other lifestyle correlates of serum folate concentrations in a healthy adult population in Crete, Greece: a cross-sectional study.

scientific article

Effect of Mediterranean diet on lipid peroxidation marker TBARS in obese patients with OSAHS under CPAP treatment: a randomised trial.

scientific article published on 15 September 2011

Effect of Mediterranean diet versus prudent diet combined with physical activity on OSAS: a randomised trial.

scientific article published on 27 October 2011

Effect of training-sample size and classification difficulty on the accuracy of genomic predictors

scientific article

Effects of different weight loss percentages on moderate to severe obstructive sleep apnoea syndrome

scientific article published on 25 May 2015

Effects of tissue handling on RNA integrity and microarray measurements from resected breast cancers

scientific article published on 27 October 2011

Enhancing reproducibility in cancer drug screening: how do we move forward?

scientific article

Estrogen receptor (ER) mRNA and ER-related gene expression in breast cancers that are 1% to 10% ER-positive by immunohistochemistry

scientific article

Examining the cost-effectiveness of baseline left ventricular function assessment among breast cancer patients undergoing anthracycline-based therapy

scientific article published on 24 April 2019

Feeding heterogeneity in ciliate populations: Effects of culture age and nutritional state

scientific article published on 01 March 1994

First international TNBC conference meeting report

scientific article published on 8 February 2018

Functional germline variants as potential co-oncogenes

scientific article published on 22 November 2017

Functional polymorphisms in cancer

scientific article

Gene signature-guided dasatinib therapy in metastatic breast cancer.

scientific article published on 29 August 2014

Genomic and Immune Profiling of a Patient With Triple-Negative Breast Cancer That Progressed During Neoadjuvant Chemotherapy Plus PD-L1 Blockade

scientific article published on 10 May 2019

Genomic grade index is associated with response to chemotherapy in patients with breast cancer

scientific article published on 13 April 2009

Genomic index of sensitivity to endocrine therapy for breast cancer.

scientific article

Genomic predictor of residual risk of recurrence after adjuvant chemotherapy and endocrine therapy in high risk estrogen receptor-positive breast cancers.

scientific article published on 5 February 2015

Germline variant burden in cancer genes correlates with age at diagnosis and somatic mutation burden

scientific article published on 15 May 2020

Global gene expression changes induced by prolonged cold ischemic stress and preservation method of breast cancer tissue.

scientific article

Gluteal adipose-tissue polyunsaturated fatty-acids profiles and depressive symptoms in obese adults with obstructive sleep apnea hypopnea syndrome: a cross-sectional study.

scientific article published on 31 January 2011

Health and nutrition education in primary schools of Crete: changes in chronic disease risk factors following a 6-year intervention programme

scientific article

History of the Cretan cohort of the Seven Countries Study

scientific article published in April 2015

Hormone receptor status and pathologic response of HER2-positive breast cancer treated with neoadjuvant chemotherapy and trastuzumab.

scientific article published on 29 July 2008

Identification and Validation of a Novel Biologics Target in Triple Negative Breast Cancer

scientific article published on 17 October 2019

Identification of serum analytes and metabolites associated with aerobic capacity.

scientific article published on 27 November 2012

Immune Gene Expression Is Associated with Genomic Aberrations in Breast Cancer

scientific article published on 20 April 2017

Immune microenvironment of triple-negative breast cancer in African-American and Caucasian women

scientific article published on 06 February 2019

Immune profiling of pre- and post-treatment breast cancer tissues from the SWOG S0800 neoadjuvant trial

scholarly article by Xiaotong Li et al published 10 April 2019 in Journal for Immunotherapy of Cancer

Impacts of Early Guideline-Directed 21-Gene Recurrence Score Testing on Adjuvant Therapy Decision Making

scientific article published on 19 October 2017

Increased epigenetic age in normal breast tissue from luminal breast cancer patients

scientific article published on 29 August 2018

Increasing accrual of minority patients in breast cancer clinical trials

scientific article published on 25 August 2020

International Expert Consensus on Primary Systemic Therapy in the Management of Early Breast Cancer: Highlights of the Fifth Symposium on Primary Systemic Therapy in the Management of Operable Breast Cancer, Cremona, Italy (2013).

scientific article published on May 2015

Intratumor Heterogeneity of Homologous Recombination Deficiency in Primary Breast Cancer

scientific article published on 6 September 2016

Is complete response the answer?

scientific article

Lack of an association of depression with n-3 polyunsaturated fatty acids in adipose tissue and serum phospholipids in healthy adults

scientific article published on 30 October 2007

Large-scale identification of novel transcripts in the human genome

scientific article published on 31 January 2007

Long-Term Prognostic Risk After Neoadjuvant Chemotherapy Associated With Residual Cancer Burden and Breast Cancer Subtype

scientific article published on 30 January 2017

Long-Term Survival of De Novo Stage IV Human Epidermal Growth Receptor 2 (HER2) Positive Breast Cancers Treated with HER2-Targeted Therapy

scientific article published on 23 August 2018

Measurement of residual breast cancer burden to predict survival after neoadjuvant chemotherapy.

scientific article published on 4 September 2007

Metabolic isoenzyme shifts in cancer as potential novel therapeutic targets.

scientific article

Microtubule-associated protein-tau is a bifunctional predictor of endocrine sensitivity and chemotherapy resistance in estrogen receptor-positive breast cancer

scientific article published on 01 April 2007

Molecular anatomy of breast cancer stroma and its prognostic value in estrogen receptor-positive and -negative cancers.

scientific article published on 30 August 2010

Morphologically-structured models of growing budding yeast populations

scientific article published on 03 March 2006

Multi-Omics Investigation of Innate Navitoclax Resistance in Triple-Negative Breast Cancer Cells

scientific article published on 08 September 2020

Multigene prognostic tests in breast cancer: past, present, future

scientific article

Multistaged corpuscular models of microbial growth: Monte Carlo simulations

scientific article published on 01 January 1995

Mutation based treatment recommendations from next generation sequencing data: a comparison of web tools

scientific article

Neoadjuvant Model in Cancer Treatment: From Clinical Opportunity to Health-Care Utility

scientific article published in May 2015

Phase 1b study of the mammalian target of rapamycin inhibitor sirolimus in combination with nanoparticle albumin-bound paclitaxel in patients with advanced solid tumors

scientific article

Predictors of Chemosensitivity in Triple Negative Breast Cancer: An Integrated Genomic Analysis

scientific article

Prospective assessment of the decision-making impact of the Breast Cancer Index in recommending extended adjuvant endocrine therapy for patients with early-stage ER-positive breast cancer

scientific article

Quantitative assessment of the spatial heterogeneity of tumor-infiltrating lymphocytes in breast cancer

scientific article published on 29 July 2016

Relationship between Complete Pathologic Response to Neoadjuvant Chemotherapy and Survival in Triple-Negative Breast Cancer.

scientific article published on 18 August 2015

Reliability of Whole-Exome Sequencing for Assessing Intratumor Genetic Heterogeneity

scientific article published on 01 November 2018

Reproducibility of research and preclinical validation: problems and solutions.

scientific article published in October 2013

Reproducibility of residual cancer burden for prognostic assessment of breast cancer after neoadjuvant chemotherapy

scientific article published on May 2015

Revisiting inconsistency in large pharmacogenomic studies

scientific article published on 16 September 2016

SETER/PR: a robust 18-gene predictor for sensitivity to endocrine therapy for metastatic breast cancer.

scientific article published on 30 May 2019

School health education programs in Crete: evaluation of behavioural and health indices a decade after initiation

scientific article published on 4 June 2010

Seven Countries Study cohort in Crete, Greece: gluteal adipose-tissue fatty-acid profiles of survivors, at 2010.

scientific article published on 5 August 2015

Single-arm, neoadjuvant, phase II trial of pertuzumab and trastuzumab administered concomitantly with weekly paclitaxel followed by 5-fluoruracil, epirubicin, and cyclophosphamide (FEC) for stage I-III HER2-positive breast cancer

scientific article published on 2 February 2018

Sirolimus and trastuzumab combination therapy for HER2-positive metastatic breast cancer after progression on prior trastuzumab therapy.

scientific article published on 17 February 2015

Smoking status in relation to serum folate and dietary vitamin intake

scientific article published on 9 September 2008

Statistical measures of transcriptional diversity capture genomic heterogeneity of cancer

scientific article

Systematic Drug Screening Identifies Tractable Targeted Combination Therapies in Triple-Negative Breast Cancer

scientific article published on 21 November 2016

T-DM1 Activity in Metastatic Human Epidermal Growth Factor Receptor 2-Positive Breast Cancers That Received Prior Therapy With Trastuzumab and Pertuzumab

scientific article published on 13 June 2016

TQuest, A Web-Based Platform to Enable Precision Medicine by Linking a Tumor's Genetic Defects to Therapeutic Options

scientific article published on 01 December 2018

Testing violations of the exponential assumption in cancer clinical trials with survival endpoints.

scientific article published on 26 September 2016

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

scientific article

The Neoadjuvant Model and Complete Pathologic Response in Breast Cancer: All or Nothing?

scientific article

The impact of RNA extraction method on accurate RNA sequencing from formalin-fixed paraffin-embedded tissues

scientific article published on 05 December 2019

The impact of communication style on patient satisfaction

scientific article published on 25 April 2019

The metabolic syndrome among preschool and school age children and adolescents in Crete in the first decade of the 21st century

scientific article published in October 2014

Thirty-gene pharmacogenomic test correlates with residual cancer burden after preoperative chemotherapy for breast cancer

scientific article published on July 2007

Towards understanding of the complex structure of growing yeast populations.

scientific article published on 26 October 2006

Treatment scheduling effects on the evolution of drug resistance in heterogeneous cancer cell populations

scientific article published on 26 May 2021

Trends in metabolic syndrome risk factors among adolescents in rural Crete between 1989 and 2011.

scientific article published in April 2014

Tumor-Infiltrating Lymphocytes and PD-L1 Expression in Pre- and Posttreatment Breast Cancers in the SWOG S0800 Phase II Neoadjuvant Chemotherapy Trial.

scientific article published on 27 March 2018

Validity of the cohort of Crete in the Seven Countries Study: A time-series study applied to the cancer mortality trend between 1960 and 2011 ⬇️

scientific article published on January 14, 2013

Whole-genome sequencing of phenotypically distinct inflammatory breast cancers reveals similar genomic alterations to non-inflammatory breast cancers

scientific article published on 26 April 2021

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