Search filters

List of works by Elizabeth Sapey

A Systematic Review of the Use of Physiological Tests Assessing the Acute Response to Treatment During Exacerbations of COPD (with a Focus on Small Airway Function)

scientific article published on 12 November 2020

A novel model and molecular therapy for Z alpha-1 antitrypsin deficiency.

scientific article

A specific proteinase 3 activity footprint in α1-antitrypsin deficiency

scientific article published on 01 July 2019

A suggested framework to reopen a clinical research laboratory during the COVID19 pandemic

scientific article published on 28 October 2020

Aberrant neutrophil functions in stable chronic obstructive pulmonary disease: the neutrophil as an immunotherapeutic target

scientific article published on 27 August 2013

Ageing, frailty and resilience in Botswana: rapid ageing, rapid change. Findings from a national working group meeting and literature review

scientific article published on 19 November 2019

Alpha-1 Antitrypsin Deficiency and Accelerated Aging: A New Model for an Old Disease?

scientific article published on 01 September 2019

An age-related numerical and functional deficit in CD19(+) CD24(hi) CD38(hi) B cells is associated with an increase in systemic autoimmunity

scientific article published on 19 July 2013

Assessing Fluid Resuscitation in Adults with Sepsis Who Are Not Mechanically Ventilated: a Systematic Review of Diagnostic Test Accuracy Studies

scientific article published on 31 May 2019

Auto-Antibodies and Inflammation

scientific article published on 01 April 2011

Behavioral and structural differences in migrating peripheral neutrophils from patients with chronic obstructive pulmonary disease.

scientific article

Building toolkits for COPD exacerbations: lessons from the past and present

scientific article published on 03 July 2019

COPD exacerbations: transforming outcomes through research.

scientific article published on 9 February 2018

Catching “Early” COPD – The Diagnostic Conundrum

scientific article published in 2021

Change in blood test results prior to diagnosis in multiple myeloma

scientific article published on 01 March 2020

Dysregulated Neutrophil Phenotype and Function in Hospitalised Non-ICU COVID-19 Pneumonia

scientific article published in 2022

Early identification of severe community-acquired pneumonia: a retrospective observational study.

scientific article published on 5 June 2019

Electronic-prescribing tools improve N-acetylcysteine prescription accuracy and timeliness for patients who present following a paracetamol overdose: A digital innovation quality-improvement project

scientific article published on 01 January 2020

Ethnicity and risk of death in patients hospitalised for COVID-19 infection in the UK: an observational cohort study in an urban catchment area

scientific article published on 01 September 2020

Ethnicity and risk of death in patients hospitalised for COVID-19 infection: an observational cohort study in an urban catchment area

scientific article published on 09 May 2020

Evaluation of NEWS2 response thresholds in a retrospective observational study from a UK acute hospital

scientific article published in 2022

Frailty and sarcopenia: The potential role of an aged immune system

scientific article published on 18 February 2017

Friend or foe? The dual role of neutrophils in lung injury and repair.

scientific article

Getting stuck or choosing to stay? Neutrophil transit times in the lung in acute inflammation and COPD

scientific article published on 16 May 2019

Habitual physical activity is associated with the maintenance of neutrophil migratory dynamics in healthy older adults.

scientific article published on 26 February 2016

Imbalances between interleukin-1 and tumor necrosis factor agonists and antagonists in stable COPD.

scientific article published on 17 March 2009

Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals

scientific article published on 30 April 2014

Inflammation and neutrophil immunosenescence in health and disease: Targeted treatments to improve clinical outcomes in the elderly

scientific article

Inter-relationships between inflammatory markers in patients with stable COPD with bronchitis: intra-patient and inter-patient variability

scientific article published on 05 December 2007

Is periodontitis a comorbidity of COPD or can associations be explained by shared risk factors/behaviors?

scientific article

Maximal mid-expiratory flow detects early lung disease in α1-antitrypsin deficiency

scientific article

Monocytes and Macrophages in Alpha-1 Antitrypsin Deficiency

scientific article published on 03 December 2020

Neutrophil chemotaxis in granulomatosis with polyangiitis (Wegener's) and idiopathic pulmonary fibrosis

scientific article published on 01 September 2011

Neutrophil phenotypes in chronic lung disease

scientific article published on 21 August 2019

Neutrophilic Inflammation in the Pathogenesis of Chronic Obstructive Pulmonary Disease

scientific article published on 01 June 2018

Neutrophils in community-acquired pneumonia: parallels in dysfunction at the extremes of age

scientific article published on 15 November 2019

Phosphoinositide 3-kinase inhibition restores neutrophil accuracy in the elderly: toward targeted treatments for immunosenescence

scientific article

Physiological tests of small airways function in diagnosing asthma: a systematic review

scientific article published on 01 December 2020

Pro-inflammatory effects of e-cigarette vapour condensate on human alveolar macrophages

scientific article published on 13 August 2018

Pulmonary Infections in the Elderly Lead to Impaired Neutrophil Targeting, Improved by Simvastatin

scientific article published on 28 June 2017

Rapid adaptation of a local healthcare digital system to COVID-19: The experience in Birmingham (UK)

scientific article published in 2021

Repurposing Treatments to Enhance Innate Immunity. Can Statins Improve Neutrophil Functions and Clinical Outcomes in COPD?

scientific article

Sepsis Induces a Dysregulated Neutrophil Phenotype That Is Associated with Increased Mortality.

scientific article

Shared mechanisms of multimorbidity in COPD, atherosclerosis and type-2 diabetes: the neutrophil as a potential inflammatory target

scientific article published on 20 March 2020

Simvastatin Improves Neutrophil Function and Clinical Outcomes in Pneumonia. A Pilot Randomized Controlled Clinical Trial

scientific article published on 01 November 2019

Simvastatin to modify neutrophil function in older patients with septic pneumonia (SNOOPI): study protocol for a randomised placebo-controlled trial

scientific article published on 22 August 2014

Small airways disease: time for a revisit?

scientific article published on 7 August 2017

Statin therapy in patients with community-acquired pneumonia.

scientific article published in October 2017

Statins for sepsis: distinguishing signal from the noise when designing clinical trials

scientific article published on 01 October 2013

TNF-α Autocrine Feedback Loops in Human Monocytes: The Pro- and Anti-Inflammatory Roles of the TNF-α Receptors Support the Concept of Selective TNFR1 Blockade In Vivo.

scientific article published on 22 September 2016

The Clinical and Inflammatory Relationships between Periodontitis and Chronic Obstructive Pulmonary Disease

scientific article published on 22 June 2020

The challenges of muscle biopsy in a community based geriatric population

article by Daisy Wilson et al published 26 November 2018 in BMC Research Notes

The impact of changes in coding on mortality reports using the example of sepsis

scientific article published in 2022

The rs361525 polymorphism does not increase production of tumor necrosis factor alpha by monocytes from alpha-1 antitrypsin deficient subjects with chronic obstructive pulmonary disease - a pilot study

scientific article

The validation of assays used to measure biomarkers in exhaled breath condensate.

scientific article

Treatment of lung disease in alpha-1 antitrypsin deficiency: a systematic review

scientific article published on 2 May 2017

Tumor necrosis factor-{alpha} rs361525 polymorphism is associated with increased local production and downstream inflammation in chronic obstructive pulmonary disease

scientific article published on 18 March 2010

Variability of sputum inflammatory mediators in COPD and α1-antitrypsin deficiency

scientific article published on 14 June 2012

Vitamin D Deficiency in Human and Murine Sepsis.

scientific article published on 14 September 2016

Vitamin D deficiency contributes directly to the acute respiratory distress syndrome (ARDS) ⬇️

scientific article

What is the evidence base for fluid resuscitation in acute medicine?

Work-life balance in academic medicine.

scientific article published in February 2015

Paulina is supported by:

About Paulina

Help