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List of works by Melita A. Gordon

A Malawian fisherman with a flail chest

A reduction in adult blood stream infection and case fatality at a large African hospital following antiretroviral therapy roll-out

scientific article published on 18 March 2014

Adding function to the genome of African Salmonella Typhimurium ST313 strain D23580

scientific article published on 15 January 2019

Antimicrobial resistance and management of invasive Salmonella disease

scientific article

Ascertaining the burden of invasive Salmonella disease in hospitalised febrile children aged under four years in Blantyre, Malawi

scientific article published on 17 July 2019

Bactericidal Immunity to Salmonella in Africans and Mechanisms Causing Its Failure in HIV Infection

scientific article

Burden of enteric fever at three urban sites in Africa and Asia: a multicentre population-based study

scientific article published on 01 December 2021

Case-control investigation of invasive Salmonella disease in Malawi reveals no evidence of environmental or animal transmission of invasive strains, and supports human to human transmission

scientific article published in 2022

Characterization of the Prophage Repertoire of African Salmonella Typhimurium ST313 Reveals High Levels of Spontaneous Induction of Novel Phage BTP1.

scientific article

Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses

article

Community Engagement Before Initiation of Typhoid Conjugate Vaccine Trial in Schools in Two Urban Townships in Blantyre, Malawi: Experience and Lessons

scientific article published on 01 March 2019

Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings

scientific article published on 22 August 2016

Distinct climate influences on the risk of typhoid compared to invasive non-typhoid Salmonella disease in Blantyre, Malawi

scientific article published on 30 December 2019

Domestic River Water Use and Risk of Typhoid Fever: Results From a Case-control Study in Blantyre, Malawi

scientific article published on 01 March 2020

Drug resistance in Salmonella enterica ser. Typhimurium bloodstream infection, Malawi.

scientific article published on November 2014

Dysregulated humoral immunity to nontyphoidal Salmonella in HIV-infected African adults

scientific article published on April 2010

Early Insights From Clinical Trials of Typhoid Conjugate Vaccine

scientific article published on 01 July 2020

Electronic data capture for large scale typhoid surveillance, household contact tracing, and health utilisation survey: Strategic Typhoid Alliance across Africa and Asia

scientific article published on 09 April 2020

Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype

scientific article published on 9 November 2009

Epidemics of invasive Salmonella enterica serovar enteritidis and S. enterica Serovar typhimurium infection associated with multidrug resistance among adults and children in Malawi

scientific article published on April 2008

Epidemiology of hepatitis B, C and D in Malawi: systematic review

scientific article published on 12 October 2018

Epidemiology, Clinical Presentation, Laboratory Diagnosis, Antimicrobial Resistance, and Antimicrobial Management of Invasive Salmonella Infections

scientific article

Erratum: Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings

scientific article published in March 2017

Estimating the economic burden of typhoid in children and adults in Blantyre, Malawi: A costing cohort study

scientific article published in 2022

Evaluating the safety, tolerability, pharmacokinetics and efficacy of clofazimine in cryptosporidiosis (CRYPTOFAZ): study protocol for a randomized controlled trial

Evaluation of a standardised Vi poly-l-lysine ELISA for serology of Vi capsular polysaccharide antibodies

scientific article published on 20 June 2020

Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease

scientific article published on 11 August 2020

Five-year single-centre experience of carcinoma of the oesophagus from Blantyre, Malawi

scientific article published on 15 October 2018

Gamma interferon enhances internalization and early nonoxidative killing of Salmonella enterica serovar Typhimurium by human macrophages and modifies cytokine responses.

scientific article published on June 2005

Genomic characterisation of invasive non-typhoidal Salmonella enterica Subspecies enterica Serovar Bovismorbificans isolates from Malawi

scientific article

Genotypic homogeneity of multidrug resistant S. Typhimurium infecting distinct adult and childhood susceptibility groups in Blantyre, Malawi

scientific article published on 27 July 2012

Global burden of invasive nontyphoidal Salmonella disease, 2010(1)

scientific article

Helicobacter pylori, HIV and Gastric Hypochlorhydria in the Malawian Population

scientific article

High-resolution single nucleotide polymorphism analysis distinguishes recrudescence and reinfection in recurrent invasive nontyphoidal Salmonella typhimurium disease

scientific article published on 7 February 2012

Homologous and heterologous re-challenge with Salmonella Typhi and Salmonella Paratyphi A in a randomised controlled human infection model

scientific article published on 20 October 2020

Immunological bases of increased susceptibility to invasive nontyphoidal Salmonella infection in children with malaria and anaemia.

scientific article published on 14 December 2017

Impact of maternal antibodies and infant gut microbiota on the immunogenicity of rotavirus vaccines in African, Indian and European infants: protocol for a prospective cohort study

scientific article published on 29 March 2017

In patient care: should the general physician now take charge?

scientific article published in February 2013

Incidence of invasive non-typhoidal Salmonella in Blantyre, Malawi between January 2011-December 2019

scientific article published in 2022

Interprofessional Education: Finding a Place to Start.

scientific article published on 16 April 2015

Intestinal Perforations Associated With a High Mortality and Frequent Complications During an Epidemic of Multidrug-resistant Typhoid Fever in Blantyre, Malawi

scientific article published on 01 July 2020

Intracontinental spread of human invasive Salmonella Typhimurium pathovariants in sub-Saharan Africa

scientific article

Invasive Salmonella exploits divergent immune evasion strategies in infected and bystander dendritic cell subsets

scientific article published in Nature Communications

Invasive non-typhoid salmonellae establish systemic intracellular infection in HIV-infected adults: an emerging disease pathogenesis

scientific article published on April 2010

Invasive non-typhoidal Salmonella typhimurium ST313 are not host-restricted and have an invasive phenotype in experimentally infected chickens

scientific article

Invasive non-typhoidal salmonella disease: an emerging and neglected tropical disease in Africa.

scientific article

Invasive nontyphoidal Salmonella disease: epidemiology, pathogenesis and diagnosis

scientific article

Invasive salmonellosis in Malawi

scientific article published on December 2008

Longevity of duodenal and peripheral T-cell and humoral responses to live-attenuated Salmonella Typhi strain Ty21a

article

Loss of Humoral and Cellular Immunity to Invasive Nontyphoidal Salmonella during Current or Convalescent Plasmodium falciparum Infection in Malawian Children

scientific article published on 17 May 2017

Mathematical Modeling to Assess the Drivers of the Recent Emergence of Typhoid Fever in Blantyre, Malawi

scientific article published in November 2015

Modelling the Contributions of Malaria, HIV, Malnutrition and Rainfall to the Decline in Paediatric Invasive Non-typhoidal Salmonella Disease in Malawi

scientific article published on 31 July 2015

Molecular Surveillance Identifies Multiple Transmissions of Typhoid in West Africa

scientific article published on 22 September 2016

Non-typhoidal salmonella (NTS) bacteraemia in Malawian adults: a severe, recrudescent, HIV-associated illness.

scientific article published on June 2003

Non-typhoidal salmonella bacteraemia among HIV-infected Malawian adults: high mortality and frequent recrudescence

scientific article published in August 2002

Non-typhoidal salmonella bacteraemia--an under-recognized feature of AIDS in African adults

scientific article

Nonspecific effects of oral vaccination with live-attenuated Typhi strain Ty21a

scientific article published on 27 February 2019

Omicron B.1.1.529 variant infections associated with severe disease are uncommon in a COVID-19 under-vaccinated, high SARS-CoV-2 seroprevalence population in Malawi

scientific article published in 2023

On the Ground in Malawi-First Typhoid Conjugate Vaccine Study in Africa

scientific article published on 01 June 2019

Oral Typhoid Vaccination With Live-Attenuated Salmonella Typhi Strain Ty21a Generates Ty21a-Responsive and Heterologous Influenza Virus-Responsive CD4+ and CD8+ T Cells at the Human Intestinal Mucosa

scientific article published on 24 January 2016

Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events

scientific article published on 11 May 2015

Pneumococcal disease in HIV-infected Malawian adults: acute mortality and long-term survival

scientific article published on July 2002

Polysaccharide-Specific Memory B Cells Predict Protection against Experimental Human Pneumococcal Carriage

scientific article published on 12 July 2016

Primary biliary cirrhosis shows association with genetic polymorphism of tumour necrosis factor alpha promoter region

scientific article published on 01 August 1999

Primary macrophages from HIV-infected adults show dysregulated cytokine responses to Salmonella, but normal internalization and killing

scientific article

Publisher Correction: Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses

article

Rapid emergence of multidrug resistant, H58-lineage Salmonella typhi in Blantyre, Malawi.

scientific article published on 24 April 2015

Review article: the aetiology, investigation and management of diarrhoea in the HIV-positive patient.

scientific article published on 20 July 2011

Role of a single noncoding nucleotide in the evolution of an epidemic African clade of Salmonella.

scientific article

Safety and immunogenicity of a typhoid conjugate vaccine among children aged 9 months to 12 years in Malawi: a nested substudy of a double-blind, randomised controlled trial

scientific article published in 2022

Salmonella identified in pigs in Kenya and Malawi reveals the potential for zoonotic transmission in emerging pork markets

scientific article published on 24 November 2020

Salmonella infections in immunocompromised adults

scientific article published on 12 May 2008

Schistosomiasis does not contribute to death or recurrence of nontyphoid Salmonella bacteremia in human immunodeficiency virus-infected Malawian adults

scientific article published on 19 November 2003

Sequential acquisition of T cells and antibodies to nontyphoidal Salmonella in Malawian children

scientific article published on 16 January 2014

Simian immunodeficiency virus-induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut.

scientific article

Stepwise evolution of Salmonella Typhimurium ST313 causing bloodstream infection in Africa

scientific article published on 21 December 2020

Sustained reduction in third-generation cephalosporin usage in adult inpatients following introduction of an antimicrobial stewardship program in a large urban hospital in Malawi

scientific article published on 15 February 2020

Synergy between Androgen Receptor Antagonism and Inhibition of mTOR and HER2 in Breast Cancer.

scientific article published on 3 May 2017

Systematic review: the etiology of esophageal squamous cell carcinoma in low-income settings

scientific article published on 14 November 2018

The Impact of Vaccination and Prior Exposure on Stool Shedding of Salmonella Typhi and Salmonella Paratyphi in 6 Controlled Human Infection Studies

scientific article published on 01 April 2019

The STRATAA study protocol: a programme to assess the burden of enteric fever in Bangladesh, Malawi and Nepal using prospective population census, passive surveillance, serological studies and healthcare utilisation surveys

scientific article published on 2 July 2017

The Surveillance for Enteric Fever in Asia Project (SEAP), Severe Typhoid Fever Surveillance in Africa (SETA), Surveillance of Enteric Fever in India (SEFI), and Strategic Typhoid Alliance Across Africa and Asia (STRATAA) Population-based Enteric Fe

scientific article published on 01 July 2020

The Typhoid Vaccine Acceleration Consortium (TyVAC): Vaccine effectiveness study designs: Accelerating the introduction of typhoid conjugate vaccines and reducing the global burden of enteric fever. Report from a meeting held on 26–27 October 2016,

scientific article published in September 2017

The fitness landscape of the African Salmonella Typhimurium ST313 strain D23580 reveals unique properties of the pBT1 plasmid

scientific article published on 27 September 2019

The human transcriptome during nontyphoid Salmonella and HIV coinfection reveals attenuated NFkappaB-mediated inflammation and persistent cell cycle disruption

scientific article

Three Epidemics of Invasive Multidrug-Resistant Salmonella Bloodstream Infection in Blantyre, Malawi, 1998-2014.

scientific article published in November 2015

Trends in antimicrobial resistance in bloodstream infection isolates at a large urban hospital in Malawi (1998-2016): a surveillance study

scientific article published on 14 August 2017

Typhoid Vaccine Acceleration Consortium Malawi: A Phase III, Randomized, Double-blind, Controlled Trial of the Clinical Efficacy of Typhoid Conjugate Vaccine Among Children in Blantyre, Malawi

scientific article published on 01 March 2019

Typhoid conjugate vaccine effectiveness in Malawi: evaluation of a test-negative design using randomised, controlled clinical trial data

scientific article published in 2023

Typhoid conjugate vaccines: making vaccine history in Africa

article

Typhoid fever and invasive nontyphoid salmonellosis, Malawi and South Africa

scientific article published on September 2010

Waning of antibody levels induced by a 13-valent pneumococcal conjugate vaccine, using a 3 + 0 schedule, within the first year of life among children younger than 5 years in Blantyre, Malawi: an observational, population-level, serosurveillance stud

scientific article published in 2022