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List of works by Wen-Chien Chou

A 3-microRNA scoring system for prognostication in de novo acute myeloid leukemia patients.

scientific article published on 27 November 2014

A knock-in Npm1 mutation in mice results in myeloproliferation and implies a perturbation in hematopoietic microenvironment

scientific article

A single-tube, sensitive multiplex method for screening of isocitrate dehydrogenase 1 (IDH1) mutations.

scientific article published on July 2010

A three-gene expression-based risk score can refine the European LeukemiaNet AML classification.

scientific article published on September 2016

AML1/RUNX1 mutations in 470 adult patients with de novo acute myeloid leukemia: prognostic implication and interaction with other gene alterations.

scientific article published on 6 October 2009

ASXL1 mutation confers poor prognosis in primary myelofibrosis patients with low JAK2V617F allele burden but not in those with high allele burden

scientific article published on 12 October 2020

Acute and chronic arsenic poisoning associated with treatment of acute promyelocytic leukaemia

scientific article published on 01 December 1998

Acute promyelocytic leukemia: recent advances in therapy and molecular basis of response to arsenic therapies.

scientific article

An mRNA expression signature for prognostication in de novo acute myeloid leukemia patients with normal karyotype.

scientific article published on 23 October 2015

Arsenic suppresses gene expression in promyelocytic leukemia cells partly through Sp1 oxidation.

scientific article published on 10 March 2005

Aurora A and NF-κB Survival Pathway Drive Chemoresistance in Acute Myeloid Leukemia via the TRAF-Interacting Protein TIFA.

scientific article published on 10 November 2016

CEBPA methylation as a prognostic biomarker in patients with de novo acute myeloid leukemia.

scientific article published on 7 October 2010

Calreticulin mutation was rarely detected in patients with myelodysplastic syndrome

scientific article published on 17 February 2014

Characteristics of Taiwanese patients of PNH in the international PNH registry

scientific article published on 04 October 2016

Chromosomal abnormalities by conventional cytogenetics and interphase fluorescence in situ hybridization in chronic lymphocytic leukemia in Taiwan, an area with low incidence--clinical implication and comparison between the West and the East.

scientific article

Chromosomal abnormalities of 200 Chinese patients with non-Hodgkin's lymphoma in Taiwan: with special reference to T-cell lymphoma

scientific article published on 01 July 2004

Clinical and biological characteristics of acute promyelocytic leukemia in Taiwan: a high relapse rate in patients with high initial and peak white blood cell counts during all-trans retinoic acid treatment

scientific article published on 01 July 1997

Clinical and microbiological characteristics of perianal infections in adult patients with acute leukemia

scientific article

Clinical and prognostic implications of Roundabout 4 (robo4) in adult patients with acute myeloid leukemia

scientific article

Clinical characteristics and treatment outcomes of patients with candidaemia due to Candida parapsilosis sensu lato species at a medical centre in Taiwan, 2000-12.

scientific article published on 3 January 2015

Clinical characteristics of candidaemia in adults with haematological malignancy, and antimicrobial susceptibilities of the isolates at a medical centre in Taiwan, 2001-2010.

scientific article published on 21 September 2012

Clinical features of patients with infections caused by Candida guilliermondii and Candida fermentati and antifungal susceptibility of the isolates at a medical centre in Taiwan, 2001-10.

scientific article published on 13 June 2013

Clinical implications of U2AF1 mutation in patients with myelodysplastic syndrome and its stability during disease progression.

scientific article

Clinical implications of minimal residual disease monitoring by quantitative polymerase chain reaction in acute myeloid leukemia patients bearing nucleophosmin (NPM1) mutations

scientific article published on 15 March 2007

Clinical implications of the SETBP1 mutation in patients with primary myelodysplastic syndrome and its stability during disease progression.

scientific article

Clonal disease of natural killer large granular lymphocytes in Taiwan

scientific article published on 01 December 1998

DNMT3A mutations in acute myeloid leukemia: stability during disease evolution and clinical implications ⬇️

scientific article published on November 10, 2011

Distinct association between aberrant methylation of Wnt inhibitors and genetic alterations in acute myeloid leukaemia ⬇️

scientific article published on November 17, 2011

Distinct clinical and biologic characteristics in adult acute myeloid leukemia bearing the isocitrate dehydrogenase 1 mutation.

scientific article published on 22 January 2010

Distinct clinical and biological features of de novo acute myeloid leukemia with additional sex comb-like 1 (ASXL1) mutations

scientific article published on 06 August 2010

Distinct mutation profile and prognostic relevance in patients with hypoplastic myelodysplastic syndromes (h-MDS).

scientific article published on 04 August 2016

Dynamic contrast-enhanced MR imaging measurement of vertebral bone marrow perfusion may be indicator of outcome of acute myeloid leukemia patients in remission.

scientific article published on 06 January 2011

Dynamics of DNMT3A mutation and prognostic relevance in patients with primary myelodysplastic syndrome.

scientific article

Efficacy, safety, and pharmacokinetics of subcutaneous azacitidine in Taiwanese patients with higher-risk myelodysplastic syndromes

scientific article published on 25 January 2017

Expression of CALR mutants causes mpl-dependent thrombocytosis in zebrafish

scientific article published on 07 October 2016

Expression of angiopoietins and vascular endothelial growth factors and their clinical significance in acute myeloid leukemia

scientific article published on 29 September 2007

Expression of cereblon protein assessed by immunohistochemicalstaining in myeloma cells is associated with superior response of thalidomide- and lenalidomide-based treatment, but not bortezomib-based treatment, in patients with multiple myeloma.

scientific article

Frequent CALR exon 9 alterations in JAK2 V617F-mutated essential thrombocythemia detected by high-resolution melting analysis.

scientific article published on 20 March 2015

GATA2 mutations in patients with acute myeloid leukemia-paired samples analyses show that the mutation is unstable during disease evolution

scientific article published on 21 September 2014

GATA2 zinc finger 1 mutations are associated with distinct clinico-biological features and outcomes different from GATA2 zinc finger 2 mutations in adult acute myeloid leukemia

scientific article published on 31 August 2018

Genetic alterations and their clinical implications in older patients with acute myeloid leukemia.

scientific article

Germline variations at JAK2, TERT, HBS1L-MYB and MECOM and the risk of myeloproliferative neoplasms in Taiwanese population

scientific article published on 12 July 2017

Gfi-1 is the transcriptional repressor of SOCS1 in acute myeloid leukemia cells.

scientific article published on 9 September 2013

Hepatitis B reactivation among 1962 patients with hematological malignancy in Taiwan.

scientific article published on 8 January 2018

Hierarchical cluster analysis of immunophenotype classify AML patients with NPM1 gene mutation into two groups with distinct prognosis

scientific article

High Incidences of Invasive Fungal Infections in Acute Myeloid Leukemia Patients Receiving Induction Chemotherapy without Systemic Antifungal Prophylaxis: A Prospective Observational Study in Taiwan

scientific article published on 10 June 2015

High Risk of Hepatitis B Reactivation among Patients with Acute Myeloid Leukemia

scientific article published on 14 May 2015

High bone marrow angiopoietin-1 expression is an independent poor prognostic factor for survival in patients with myelodysplastic syndromes ⬇️

scientific article published on August 30, 2011

Higher Decorin Levels in Bone Marrow Plasma Are Associated with Superior Treatment Response to Novel Agent-Based Induction in Patients with Newly Diagnosed Myeloma - A Retrospective Study

scientific article published on 17 September 2015

Higher HOPX expression is associated with distinct clinical and biological features and predicts poor prognosis in de novo acute myeloid leukemia

scientific article

Higher bone marrow LGALS3 expression is an independent unfavorable prognostic factor for overall survival in patients with acute myeloid leukemia.

scientific article published on 28 February 2013

Higher lipocalin 2 expression may represent an independent favorable prognostic factor in cytogenetically normal acute myeloid leukemia.

scientific article

Hyperleukocytosis is associated with distinct genetic alterations and is an independent poor-risk factor in de novo acute myeloid leukemia patients.

scientific article published on 6 April 2018

Hypovolemic shock and mortality after ingestion of Tripterygium wilfordii hook F.: a case report

scientific article published on 01 April 1995

IDH mutations are closely associated with mutations of DNMT3A, ASXL1 and SRSF2 in patients with myelodysplastic syndromes and are stable during disease evolution

scientific article published on 20 November 2013

IPSS-R in 555 Taiwanese patients with primary MDS: Integration of monosomal karyotype can better risk-stratify the patients

scientific article published on 19 June 2014

Incorporation of mutations in five genes in the revised International Prognostic Scoring System can improve risk stratification in the patients with myelodysplastic syndrome.

scientific article published on 4 April 2018

Integration of cytogenetic and molecular alterations in risk stratification of 318 patients with de novo non-M3 acute myeloid leukemia.

scientific article published on 9 August 2013

Knock-out of Hopx disrupts stemness and quiescence of hematopoietic stem cells in mice

scientific article published on 12 June 2020

Marrow angiogenesis-associated factors as prognostic biomarkers in patients with acute myelogenous leukaemia.

scientific article published on 11 September 2007

Marrow osteopontin level as a prognostic factor in acute myeloid leukaemia

scientific article published on 07 April 2008

Mayo Alliance Prognostic Model for Myelodysplastic Syndromes: Integration of Genetic and Clinical Information

scientific article published on 14 June 2018

Multicenter, randomized, open-label, phase III trial of decitabine versus patient choice, with physician advice, of either supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed acute myeloid leukemia

scientific article

Nucleophosmin mutations in de novo acute myeloid leukemia: the age-dependent incidences and the stability during disease evolution

scientific article published on 01 March 2006

Persistence of mutant isocitrate dehydrogenase in patients with acute myeloid leukemia in remission

scientific article published on 16 August 2011

Prognostic impacts and dynamic changes of cohesin complex gene mutations in de novo acute myeloid leukemia

scientific article published on 29 December 2017

Prognostic implication of gene mutations on overall survival in the adult acute myeloid leukemia patients receiving or not receiving allogeneic hematopoietic stem cell transplantations

scientific article published on 24 August 2014

Prognostic significance of NPM1 mutation-modulated microRNA-mRNA regulation in acute myeloid leukemia.

scientific article published on 16 September 2015

Psoas abscess caused by non-typhoid Salmonella in a patient with severe aplastic anemia.

scientific article

RUNX1 gene mutation in primary myelodysplastic syndrome--the mutation can be detected early at diagnosis or acquired during disease progression and is associated with poor outcome

scientific article published on 01 November 2007

Rapid Assessment of the Heterogeneous Methylation Status of CEBPA in Patients with Acute Myeloid Leukemia by Using High-Resolution Melting Profile ⬇️

scientific article published on June 30, 2011

Rapid and sensitive detection of CALR exon 9 mutations using high-resolution melting analysis.

scientific article published on 15 November 2014

Reduced incidence of interstitial pneumonitis after allogeneic hematopoietic stem cell transplantation using a modified technique of total body irradiation

scientific article

Risk factors and clinical outcomes of acute myeloid leukaemia with central nervous system involvement in adults

scientific article published on 2 May 2015

SETBP1 mutations drive leukemic transformation in ASXL1-mutated MDS.

scientific article published on 13 October 2014

SF3B1 mutations in patients with myelodysplastic syndromes: the mutation is stable during disease evolution.

scientific article

Sensitive measurement of quantity dynamics of FLT3 internal tandem duplication at early time points provides prognostic information ⬇️

scientific article published on August 6, 2010

Severe pulmonary complications after initial treatment with Rituximab for the Asian-variant of intravascular lymphoma

scientific article published on 01 January 2007

Splicing factor mutations predict poor prognosis in patients with de novo acute myeloid leukemia

scientific article published on 24 January 2016

TET2 mutation is an unfavorable prognostic factor in acute myeloid leukemia patients with intermediate-risk cytogenetics

scientific article

TP53 mutations in de novo acute myeloid leukemia patients: longitudinal follow-ups show the mutation is stable during disease evolution.

scientific article published on 31 July 2015

The N-terminal CEBPA mutant in acute myeloid leukemia impairs CXCR4 expression

scientific article

The clinical implication of SRSF2 mutation in patients with myelodysplastic syndrome and its stability during disease evolution

scientific article published on 29 August 2012

The distinct biological implications of Asxl1 mutation and its roles in leukemogenesis revealed by a knock-in mouse model

scientific article

The prognostic impact and stability of Isocitrate dehydrogenase 2 mutation in adult patients with acute myeloid leukemia

scientific article published on 16 November 2010

The prognostic significance of global aberrant alternative splicing in patients with myelodysplastic syndrome

scientific article published on 13 August 2018

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