List of works - Yuan-Yeh Kuo

ASXL1 mutation confers poor prognosis in primary myelofibrosis patients with low JAK2V617F allele burden but not in those with high allele burden

scientific article published on 12 October 2020

Calreticulin mutation was rarely detected in patients with myelodysplastic syndrome

scientific article published on 17 February 2014

Characterization of acute myeloid leukemia with MLL rearrangements--no increase in the incidence of coexpression of lymphoid-associated antigens on leukemic blasts

scientific article published on 01 June 2000

Clinical and prognostic implications of Roundabout 4 (robo4) in adult patients with acute myeloid leukemia

scientific article

Clinical implications of U2AF1 mutation in patients with myelodysplastic syndrome and its stability during disease progression.

scientific article

Clinical implications of the SETBP1 mutation in patients with primary myelodysplastic syndrome and its stability during disease progression.

scientific article

Control of dTTP pool size by anaphase promoting complex/cyclosome is essential for the maintenance of genetic stability

scientific article

Correction for Kuo and Chang, GATA-1 and Gfi-1B Interplay To Regulate Bcl-xL Transcription

scientific article published on March 2017

DNMT3A mutations in acute myeloid leukemia: stability during disease evolution and clinical implications ⬇️

scientific article published on November 10, 2011

Distinct association between aberrant methylation of Wnt inhibitors and genetic alterations in acute myeloid leukaemia ⬇️

scientific article published on November 17, 2011

Distinct molecular genetics of chronic lymphocytic leukemia in Taiwan: clinical and pathogenetic implications.

scientific article

Distinct mutation profile and prognostic relevance in patients with hypoplastic myelodysplastic syndromes (h-MDS).

scientific article published on 04 August 2016

Dynamics of ASXL1 mutation and other associated genetic alterations during disease progression in patients with primary myelodysplastic syndrome.

scientific article published on 17 January 2014

Dynamics of DNMT3A mutation and prognostic relevance in patients with primary myelodysplastic syndrome.

scientific article

Expression of CALR mutants causes mpl-dependent thrombocytosis in zebrafish

scientific article published on 07 October 2016

Frequent CALR exon 9 alterations in JAK2 V617F-mutated essential thrombocythemia detected by high-resolution melting analysis.

scientific article published on 20 March 2015

GATA-1 and Gfi-1B interplay to regulate Bcl-xL transcription

scientific article

GATA2 mutations in patients with acute myeloid leukemia-paired samples analyses show that the mutation is unstable during disease evolution

scientific article published on 21 September 2014

GATA2 zinc finger 1 mutations are associated with distinct clinico-biological features and outcomes different from GATA2 zinc finger 2 mutations in adult acute myeloid leukemia

scientific article published on 31 August 2018

Genetic alterations and their clinical implications in older patients with acute myeloid leukemia.

scientific article

Germline variations at JAK2, TERT, HBS1L-MYB and MECOM and the risk of myeloproliferative neoplasms in Taiwanese population

scientific article published on 12 July 2017

Gfi-1 is the transcriptional repressor of SOCS1 in acute myeloid leukemia cells.

scientific article published on 9 September 2013

Higher HOPX expression is associated with distinct clinical and biological features and predicts poor prognosis in de novo acute myeloid leukemia

scientific article

Hyperleukocytosis is associated with distinct genetic alterations and is an independent poor-risk factor in de novo acute myeloid leukemia patients.

scientific article published on 6 April 2018

IDH mutations are closely associated with mutations of DNMT3A, ASXL1 and SRSF2 in patients with myelodysplastic syndromes and are stable during disease evolution

scientific article published on 20 November 2013

IPSS-R in 555 Taiwanese patients with primary MDS: Integration of monosomal karyotype can better risk-stratify the patients

scientific article published on 19 June 2014

Incorporation of long non-coding RNA expression profile in the 2017 ELN risk classification can improve prognostic prediction of acute myeloid leukemia patients

scientific article published on 17 January 2019

Incorporation of mutations in five genes in the revised International Prognostic Scoring System can improve risk stratification in the patients with myelodysplastic syndrome.

scientific article published on 4 April 2018

Increased B cell activation is present in JAK2V617F-mutated, CALR-mutated and triple-negative essential thrombocythemia

scientific article

Integration of cytogenetic and molecular alterations in risk stratification of 318 patients with de novo non-M3 acute myeloid leukemia.

scientific article published on 9 August 2013

Loading of DNA-binding factors to an erythroid enhancer.

scientific article

Prognostic impacts and dynamic changes of cohesin complex gene mutations in de novo acute myeloid leukemia

scientific article published on 29 December 2017

Rapid and sensitive detection of CALR exon 9 mutations using high-resolution melting analysis.

scientific article published on 15 November 2014

SF3B1 mutations in patients with myelodysplastic syndromes: the mutation is stable during disease evolution.

scientific article

Splicing factor mutations predict poor prognosis in patients with de novo acute myeloid leukemia

scientific article published on 24 January 2016

TET2 mutation is an unfavorable prognostic factor in acute myeloid leukemia patients with intermediate-risk cytogenetics

scientific article

TP53 mutations in de novo acute myeloid leukemia patients: longitudinal follow-ups show the mutation is stable during disease evolution.

scientific article published on 31 July 2015

Targeted next-generation sequencing identified novel mutations in triple-negative myeloproliferative neoplasms

scientific article

The Inhibition of Wnt Restrain KRASG12V-Driven Metastasis in Non-Small-Cell Lung Cancer

scientific article published on 31 March 2020

The N-terminal CEBPA mutant in acute myeloid leukemia impairs CXCR4 expression

scientific article

The clinical implication of SRSF2 mutation in patients with myelodysplastic syndrome and its stability during disease evolution

scientific article published on 29 August 2012

The distinct biological implications of Asxl1 mutation and its roles in leukemogenesis revealed by a knock-in mouse model

scientific article

List of works by Yuan-Yeh Kuo

ASXL1 mutation confers poor prognosis in primary myelofibrosis patients with low JAK2V617F allele burden but not in those with high allele burden

Calreticulin mutation was rarely detected in patients with myelodysplastic syndrome

Characterization of acute myeloid leukemia with MLL rearrangements--no increase in the incidence of coexpression of lymphoid-associated antigens on leukemic blasts

Clinical and prognostic implications of Roundabout 4 (robo4) in adult patients with acute myeloid leukemia

Clinical implications of U2AF1 mutation in patients with myelodysplastic syndrome and its stability during disease progression.

Clinical implications of the SETBP1 mutation in patients with primary myelodysplastic syndrome and its stability during disease progression.

Control of dTTP pool size by anaphase promoting complex/cyclosome is essential for the maintenance of genetic stability

Correction for Kuo and Chang, GATA-1 and Gfi-1B Interplay To Regulate Bcl-xL Transcription

DNMT3A mutations in acute myeloid leukemia: stability during disease evolution and clinical implications ⬇️

Distinct association between aberrant methylation of Wnt inhibitors and genetic alterations in acute myeloid leukaemia ⬇️

Distinct molecular genetics of chronic lymphocytic leukemia in Taiwan: clinical and pathogenetic implications.

Distinct mutation profile and prognostic relevance in patients with hypoplastic myelodysplastic syndromes (h-MDS).

Dynamics of ASXL1 mutation and other associated genetic alterations during disease progression in patients with primary myelodysplastic syndrome.

Dynamics of DNMT3A mutation and prognostic relevance in patients with primary myelodysplastic syndrome.

Expression of CALR mutants causes mpl-dependent thrombocytosis in zebrafish

Frequent CALR exon 9 alterations in JAK2 V617F-mutated essential thrombocythemia detected by high-resolution melting analysis.

GATA-1 and Gfi-1B interplay to regulate Bcl-xL transcription

GATA2 mutations in patients with acute myeloid leukemia-paired samples analyses show that the mutation is unstable during disease evolution

GATA2 zinc finger 1 mutations are associated with distinct clinico-biological features and outcomes different from GATA2 zinc finger 2 mutations in adult acute myeloid leukemia

Genetic alterations and their clinical implications in older patients with acute myeloid leukemia.

Germline variations at JAK2, TERT, HBS1L-MYB and MECOM and the risk of myeloproliferative neoplasms in Taiwanese population

Gfi-1 is the transcriptional repressor of SOCS1 in acute myeloid leukemia cells.

Higher HOPX expression is associated with distinct clinical and biological features and predicts poor prognosis in de novo acute myeloid leukemia

Hyperleukocytosis is associated with distinct genetic alterations and is an independent poor-risk factor in de novo acute myeloid leukemia patients.

IDH mutations are closely associated with mutations of DNMT3A, ASXL1 and SRSF2 in patients with myelodysplastic syndromes and are stable during disease evolution

IPSS-R in 555 Taiwanese patients with primary MDS: Integration of monosomal karyotype can better risk-stratify the patients

Incorporation of long non-coding RNA expression profile in the 2017 ELN risk classification can improve prognostic prediction of acute myeloid leukemia patients

Incorporation of mutations in five genes in the revised International Prognostic Scoring System can improve risk stratification in the patients with myelodysplastic syndrome.

Increased B cell activation is present in JAK2V617F-mutated, CALR-mutated and triple-negative essential thrombocythemia

Integration of cytogenetic and molecular alterations in risk stratification of 318 patients with de novo non-M3 acute myeloid leukemia.

Loading of DNA-binding factors to an erythroid enhancer.

Prognostic impacts and dynamic changes of cohesin complex gene mutations in de novo acute myeloid leukemia

Rapid and sensitive detection of CALR exon 9 mutations using high-resolution melting analysis.

SF3B1 mutations in patients with myelodysplastic syndromes: the mutation is stable during disease evolution.

Splicing factor mutations predict poor prognosis in patients with de novo acute myeloid leukemia

TET2 mutation is an unfavorable prognostic factor in acute myeloid leukemia patients with intermediate-risk cytogenetics

TP53 mutations in de novo acute myeloid leukemia patients: longitudinal follow-ups show the mutation is stable during disease evolution.

Targeted next-generation sequencing identified novel mutations in triple-negative myeloproliferative neoplasms

The Inhibition of Wnt Restrain KRASG12V-Driven Metastasis in Non-Small-Cell Lung Cancer

The N-terminal CEBPA mutant in acute myeloid leukemia impairs CXCR4 expression

The clinical implication of SRSF2 mutation in patients with myelodysplastic syndrome and its stability during disease evolution

The distinct biological implications of Asxl1 mutation and its roles in leukemogenesis revealed by a knock-in mouse model