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List of works by Cristina Legnani

A new rapid bedside assay for D-dimer measurement (Simplify D-dimer) in the diagnostic work-up for deep vein thrombosis

scientific article published on 01 December 2003

A new rapid bedside assay for quantitative testing of D-Dimer (Cardiac D-Dimer) in the diagnostic work-up for deep vein thrombosis

scientific article published in January 2003

A new warfarin dosing algorithm including VKORC1 3730 G > A polymorphism: comparison with results obtained by other published algorithms

scientific article published on 19 February 2012

A novel missense mutation (Thr176?IIe) at the putative hinge of the neo N-terminus of activated protein C

scientific article published on 01 April 1995

Abnormally short activated partial thromboplastin time values are associated with increased risk of recurrence of venous thromboembolism after oral anticoagulation withdrawal

article by Cristina Legnani et al published July 2006 in British Journal of Haematology

Activated protein C resistance in deep-vein thrombosis

scientific article published on 01 February 1994

Activated protein C resistance: a comparison between two clotting assays and their relationship to the presence of the factor V Leiden mutation

scientific article published on 01 June 1996

Acute effects of defibrotide, an experimental antithrombotic agent, on fibrinolysis and blood prostanoids in man

scientific article published on 01 January 1988

Additive thrombin inhibition by fast moving heparin and dermatan sulfate explains the anticoagulant effect of sulodexide, a natural mixture of glycosaminoglycans

scientific article

Age and gender specific cut-off values to improve the performance of D-dimer assays to predict the risk of venous thromboembolism recurrence

scientific article published on 17 May 2011

An evaluation of several laboratory tests and test combinations in the detection of lupus anticoagulant

scientific article published on 01 January 1992

Antithrombin III (ATIII) replacement therapy in patients with sepsis and/or postsurgical complications: a controlled double-blind, randomized, multicenter study.

scientific article published in April 1998

Aprotinin in orthotopic liver transplantation: evidence for a prohemostatic, but not a prothrombotic, effect

scientific article published on 01 October 2001

Ascites apheresis, concentration and reinfusion for the treatment of massive or refractory ascites in cirrhosis

scientific article published on 01 February 1994

Assessment of activated partial thromboplastin time and factor IX in subjects attending an anticoagulation clinic

scientific article published on 01 September 2000

Asymptomatic carriership of factor V Leiden and genotypes of the fibrinogen gene cluster

scientific article published in May 2003

Bleeding and thrombotic complications during treatment with direct oral anticoagulants or vitamin K antagonists in venous thromboembolic patients included in the prospective, observational START2-register

scientific article published on 27 November 2020

Blood coagulation changes in homocystinuria: effects of pyridoxine and other specific therapy

scientific article published on 01 December 1986

Cirrhosis does not shift the circadian phase of plasma fibrinolysis

scientific article published in June 2002

Clinical histories and molecular characterization of two afibrinogenemic patients: insights into clinical management.

scientific article published on 10 October 2011

Coagulation and fibrinolysis in orthotopic liver transplantation: role of the recipient's disease and use of antithrombin III concentrates. S. Orsola Working Group on Liver Transplantation.

scientific article published on January 1991

Comparative evaluation of D-dimer assays for exclusion of deep venous thrombosis in symptomatic outpatients.

scientific article published in January 2003

Comparison of five specific assays for determination of dabigatran plasma concentrations in patients enrolled in the START-Laboratory Register

scientific article published on 3 January 2018

Comparison of new rapid methods for D-dimer measurement to exclude deep vein thrombosis in symptomatic outpatients ⬇️

scientific article published on 01 July 1997

Complement components and fibrinogen: correlations and association with previous myocardial infarction

scientific article published on 01 January 1995

D-dimer and factor VIII are independent risk factors for recurrence after anticoagulation withdrawal for a first idiopathic deep vein thrombosis

scientific article published on 04 March 2008

D-dimer and residual vein obstruction as risk factors for recurrence during and after anticoagulation withdrawal in patients with a first episode of provoked deep-vein thrombosis.

scientific article published on 28 February 2011

D-dimer for the diagnosis of upper extremity deep and superficial venous thrombosis

scientific article published on 14 February 2015

D-dimer levels during and after anticoagulation withdrawal in patients with venous thromboembolism treated with non-vitamin K anticoagulants

scientific article published on 16 July 2019

D-dimer levels in combination with residual venous obstruction and the risk of recurrence after anticoagulation withdrawal for a first idiopathic deep vein thrombosis

scholarly article by Benilde Cosmi et al published November 2005 in Thrombosis and Haemostasis

D-dimer testing to determine the duration of anticoagulant therapy

scientific article published on September 2007

D-dimer testing to determine the duration of anticoagulation therapy

scientific article

D-dimer testing, with gender-specific cutoff levels, is of value to assess the individual risk of venous thromboembolic recurrence in non-elderly patients of both genders: a post hoc analysis of the DULCIS study

scientific article published on 05 November 2019

D-dimer use for deep venous thrombosis exclusion in elderly patients: a comparative analysis of three different approaches to establish cut-off values for an assay with results expressed in D-dimer units

article

D-dimer, FVIII and thrombotic burden in the acute phase of deep vein thrombosis in relation to the risk of post-thrombotic syndrome

scientific article published on 8 June 2014

Design and rationale of a randomized, placebo-controlled trial on the efficacy and safety of sulodexide for extended treatment in elderly patients after a first venous thromboembolism

scientific article published on 25 May 2020

Diagnosis of deep vein thrombosis

scholarly article by Gualtiero Palareti et al published October 2006 in Seminars in Thrombosis and Hemostasis

Diagnostic Accuracy of a New d-Dimer Assay (Sclavo Auto d-Dimer) for Exclusion of Deep Vein Thrombosis in Symptomatic Outpatients

scientific article published on 09 July 2016

Different cut-off values of quantitative D-dimer methods to predict the risk of venous thromboembolism recurrence: a post-hoc analysis of the PROLONG study

article

Discrepancy of the international normalized ratio observed in the external quality assessment survey: a cause for concern ⬇️

scientific article published on April 1, 2012

Duration of anticoagulation after isolated pulmonary embolism

scientific article published on 25 February 2016

Effects of unfractioned heparin and low-molecular-weight heparin on osteoprotegerin and RANKL plasma levels in haemodialysis patients

scientific article published on 20 July 2010

Endothelial activation in patients with superficial vein thrombosis (SVT) of the lower limbs

scientific article published on 27 June 2017

Evaluation of a chemiluminescent immunoassay, the HemosIL AcuStar D-Dimer, in outpatients with clinically suspected deep venous thrombosis

scientific article published on 03 September 2015

Evaluation of a new automated panel of assays for the detection of anti-PF4/heparin antibodies in patients suspected of having heparin-induced thrombocytopenia

scientific article

Evaluation of the prevalence of severe hyperhomocysteinemia in adult patients with thrombosis who underwent screening for thrombophilia.

scientific article published on 16 October 2013

Evolution of untreated calf deep-vein thrombosis in high risk symptomatic outpatients: the blind, prospective CALTHRO study

scientific article published on 05 August 2010

External validation of the DASH prediction rule: a retrospective cohort study.

scientific article published in August 2017

G1691A factor V and G20210A FII mutations, acute ischemic stroke of unknown cause, and patent foramen ovale.

scientific article published on 19 August 2012

How the direct oral anticoagulant apixaban affects hemostatic parameters. Results of a multicenter multiplatform study

scientific article published on 01 February 2015

Hyperhomocyst(e)inemia and a common methylenetetrahydrofolate reductase mutation (Ala223Val MTHFR) in patients with inherited thrombophilic coagulation defects.

scientific article published in November 1997

Incidence of a first thromboembolic event in carriers of isolated lupus anticoagulant

scientific article published on 22 October 2014

Increased fetal loss in women with heritable thrombophilia.

scientific article published in October 1996

Influence of low-density lipoprotein (LDL) receptor-related protein and ABO blood group genotypes on factor XI levels

scientific article published on 01 April 2008

Influence of proband's characteristics on the risk for venous thromboembolism in relatives with factor V Leiden or prothrombin G20210A polymorphisms.

scientific article published on 2 August 2013

Inherited and acquired thrombophilic alterations in patients with superficial vein thrombosis of lower limbs

scientific article published on 06 February 2014

Interlaboratory variability in the measurement of direct oral anticoagulants: results from the external quality assessment scheme

scientific article published on 10 January 2018

International collaborative study for the calibration of proposed International Standards for thromboplastin, rabbit, plain, and for thromboplastin, recombinant, human, plain

scientific article published on 24 October 2017

Intravascular coagulation phenomena associated with prevalent fall in fibrinogen and plasminogen during L-asparaginase treatment in leukemic children

scientific article published on 01 January 1988

Low drug levels and thrombotic complications in high-risk atrial fibrillation patients treated with direct oral anticoagulants

scientific article published on 17 April 2018

Measurement of factor XIII (FXIII) activity by an automatic ammonia release assay using iodoacetamide blank-procedure: no more overestimation in the low activity range and better detection of severe FXIII deficiencies

scientific article

Modulation of factor V levels in plasma by polymorphisms in the C2 domain.

scientific article

Molecular defects in CRM+ factor VII deficiencies: modelling of missense mutations in the catalytic domain of FVII

scientific article published on 01 March 1994

More on: high thrombin generation and the risk of recurrent venous thromboembolism.

scientific article published on 6 March 2009

Mortality and inherited thrombophilia: results from the European Prospective Cohort on Thrombophilia.

scientific article published in February 2012

Multicenter evaluation of a new quantitative highly sensitive D-dimer assay, the Hemosil D-dimer HS 500, in patients with clinically suspected venous thromboembolism

scientific article published on 15 August 2009

No early signs of atherosclerotic alterations in carriers of inherited thrombophilia

scientific article published on 09 June 2010

Obstetric complications and pregnancy-related venous thromboembolism: The effect of low-molecular-weight heparin on their prevention in carriers of factor V Leiden or prothrombin G20210A mutation

scientific article published on 25 January 2012

Obstetric implications of fetal inherited thrombophilia in thrombophilic women

scientific article published on 19 November 2013

Pharmacodynamics of low molecular weight heparin in patients undergoing bariatric surgery: a prospective, randomised study comparing two doses of parnaparin (BAFLUX study).

scientific article published on 30 May 2009

Plasma levels of direct oral anticoagulants in real life patients with atrial fibrillation: Results observed in four anticoagulation clinics

scientific article published on 2 December 2015

Poor anticoagulation quality in the first 3 months after unprovoked venous thromboembolism is a risk factor for long-term recurrence.

scientific article published in May 2005

Poor comparability of coagulation screening test with specific measurement in patients receiving direct oral anticoagulants: results from a multicenter/multiplatform study.

scientific article published on 27 August 2016

Predictive value of D-dimer test for recurrent venous thromboembolism after anticoagulation withdrawal in subjects with a previous idiopathic event and in carriers of congenital thrombophilia

article by Gualtiero Palareti et al published 22 July 2003 in Circulation

Protein S activity in patients with heredofamilial protein S deficiency and in patients with juvenile venous thrombosis. Results of a functional method

scientific article published on 01 December 1991

Psychological impact of testing for thrombophilic alterations

scientific article published in September 2006

Rapid detection of a protein C gene mutation present in the asymptomatic and not in the thrombosis-prone lineage.

scientific article published in June 1992

Recurrent 'Migrainelike' Episodes in Patients With HIV Disease

scientific article published in July 1997

Repeated graft loss caused by recurrent hepatic artery thrombosis after liver transplantation

scholarly article by Marco Vivarelli et al published June 2003 in Liver Transplantation

Risk factors for recurrent events in subjects with superficial vein thrombosis in the randomized clinical trial SteFlux (Superficial Thromboembolism Fluxum).

scientific article

Risk of early recurrent fetal loss and levels of thrombin-activatable fibrinolysis inhibitor

scientific article published on 26 October 2011

Risks factors for highly unstable response to oral anticoagulation: a case-control study

scientific article

Rivaroxaban in the Treatment of Heparin-Induced Thrombocytopenia.

scientific article

Role of family history in identifying women with thrombophilia and higher risk of venous thromboembolism during oral contraception

Screening for activated protein C resistance before oral contraceptive treatment: a pilot study

scientific article published on 01 May 1999

Screening for thrombophilia and antithrombotic prophylaxis in pregnancy: Guidelines of the Italian Society for Haemostasis and Thrombosis (SISET).

scientific article published on 11 August 2009

Study of a protein S gene polymorphism at DNA and mRNA level in a family with symptomatic protein S deficiency

scientific article published on 01 September 1993

Thalidomide-dexamethasone as up-front therapy for patients with newly diagnosed multiple myeloma: thrombophilic alterations, thrombotic complications, and thromboprophylaxis with low-dose warfarin

scientific article published on 23 February 2010

The "lytic state" during orthotopic liver transplantation: plasminogen activators and other protease activities

scientific article published on 01 January 1993

The F11 rs2289252 polymorphism is associated with FXI activity levels and APTT ratio in women with thrombosis.

scientific article published on 25 May 2012

The Heterozygous 20210 G/A Prothrombin Genotype Is Associated With Early Venous Thrombosis in Inherited Thrombophilias and Is Not Increased in Frequency in Artery Disease ⬇️

scientific article published on November 1, 1997

The Wells rule and D-dimer for the diagnosis of isolated distal deep vein thrombosis.

scientific article published in November 2012

The factor VIII D1241E polymorphism is associated with decreased factor VIII activity and not with activated protein C resistance levels.

scientific article

The incidence of heparin-induced thrombocytopenia in patients treated with low molecular weight heparin for superficial vein thrombosis.

scientific article

The influence of VKORC1 3730 G > A polymorphism on warfarin dose: reply

scientific article published on 12 October 2012

The risk of a first and a recurrent venous thrombosis associated with an elevated D-dimer level and an elevated thrombin potential: results of the THE-VTE study: comment.

scientific article

The role of tumor markers in the diagnosis of hepatocellular carcinoma, with special reference to the des-gamma-carboxy prothrombin

scientific article published on 01 July 1995

Thrombin generation and intracranial atherosclerotic disease in patients with a transient ischaemic attack.

scientific article published on 09 May 2017

Thrombocytopenia during fondaparinux prophylaxis: HIT or something different?

scientific article published on 5 May 2010

Thrombophilic risk factors and peripheral arterial disease severity.

scientific article published on 13 April 2010

Thrombotic risk factors and cardiovascular events after endovascular intervention for peripheral arterial disease

scientific article published on 05 October 2011

Use of D-dimer testing to determine duration of anticoagulation, risk of cardiovascular events and occult cancer after a first episode of idiopathic venous thromboembolism: the extended follow-up of the PROLONG study

scientific article published on 14 March 2009

Usefulness of repeated D-dimer testing after stopping anticoagulation for a first episode of unprovoked venous thromboembolism: the PROLONG II prospective study

scientific article published on 16 November 2009

Using an age-dependent D-dimer cut-off value increases the number of older patients in whom deep vein thrombosis can be safely excluded ⬇️

scientific article published on April 17, 2012

Variability of cut-off values for the detection of lupus anticoagulants: results of an international multicenter multiplatform study.

scientific article published on 17 March 2017

Venous thromboembolism in young women; role of thrombophilic mutations and oral contraceptive use

scientific article published on 01 June 2002

t-PA Activity elicited by venous occlusion or DDAVP infusion does not produce plasmin activity in normal subjects

scientific article published on 01 September 1990

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