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List of works by Gilda Tachedjian

4th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention.

scientific article published in December 2007

A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in rats

scientific article published on 06 March 2019

Alteration of the proline at position 7 of the HIV-1 spacer peptide p1 suppresses viral infectivity in a strain dependent manner

scientific article published in January 2007

Analysis of mutations and suppressors affecting interactions between the subunits of the HIV type 1 reverse transcriptase

scientific article published on June 2000

Analysis of the contribution of reverse transcriptase and integrase proteins to retroviral RNA dimer conformation

scientific article

Anti-HIV-1 Activity of Lactic Acid in Human Cervicovaginal Fluid.

scientific article published on 5 July 2018

Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis

scientific article

Antiretroviral compounds: mechanisms underlying failure of HAART to eradicate HIV-1.

scientific article published in January 2005

Antiviral strategies in chronic hepatitis B virus infection: II. Inhibition of duck hepatitis B virus in vitro using conventional antiviral agents and supercoiled-DNA active compounds.

scientific article published on June 1990

Bats and Reverse Transcribing RNA and DNA Viruses

Bats and Rodents Shape Mammalian Retroviral Phylogeny

scientific article

Biology of mucosally transmitted sexual infection-translating the basic science into novel HIV intervention: a workshop summary

scientific article

Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT.

scientific article published on May 2007

Clinical effects and in vitro studies of trifluorothymidine combined with interferon-alpha for treatment of drug-resistant and -sensitive herpes simplex virus infections

scientific article published on July 1, 1992

Contraction of the type I IFN locus and unusual constitutive expression of IFN-α in bats

scientific article

Coresistance to zidovudine and foscarnet is associated with multiple mutations in the human immunodeficiency virus type 1 reverse transcriptase

scientific article

Critical Review: Mechanisms of HIV Transmission in Depo-Provera Users: The Likely Role of Hypoestrogenism

scientific article

Current and Emerging Drug Targets for Human Immunodeficiency Virus

scientific article

Decoding the membrane activity of the cyclotide kalata B1: the importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities

scientific article

Differential evolution of antiretroviral restriction factors in pteropid bats as revealed by APOBEC3 gene complexity

scientific article published on 29 March 2018

Dimerization of human immunodeficiency virus type 1 reverse transcriptase as an antiviral target.

scientific article

Discovery of retroviral homologs in bats: implications for the origin of mammalian gammaretroviruses

scientific article (publication date: April 2012)

Drug Resistant SIV Strains Carrying Higher-Fidelity K65R and Q151N Reverse Transcriptase Mutations Are Less Fit In Vivo

article by Sarah B. Lloyd et al published October 2014 in AIDS Research and Human Retroviruses

Efavirenz enhances the proteolytic processing of an HIV-1 pol polyprotein precursor and reverse transcriptase homodimer formation

scientific article published in January 2005

Effect of Reverse Transcriptase Inhibitors and Mutations on the Low-Cost Cavidi Reverse Transcriptase Viral Load Assay

scientific article published on 01 December 2009

Enhancement of human immunodeficiency virus type 1 replication is not intrinsic to all polyanion-based microbicides.

scientific article published on 15 June 2009

Evaluation of a low cost reverse transcriptase assay for plasma HIV-1 viral load monitoring

scientific article

Fragment Based Strategies for Discovery of Novel HIV-1 Reverse Transcriptase and Integrase Inhibitors

scientific article published on September 2015

HIV-1 infection of T cells and macrophages are differentially modulated by virion-associated Hck: a Nef-dependent phenomenon

scientific article published on 18 September 2013

High fidelity simian immunodeficiency virus reverse transcriptase mutants have impaired replication in vitro and in vivo

scientific article published on 18 February 2016

Host and Viral Proteins Modulating Ebola and Marburg Virus Egress

scientific article published on 03 January 2019

Host-pathogen interactions of retroviruses

scientific article

Identification of diverse full-length endogenous betaretroviruses in megabats and microbats

scientific article (publication date: 27 March 2013)

Identification of diverse groups of endogenous gammaretroviruses in mega- and microbats

scientific article published on 13 June 2012

Identification of mechanistically distinct inhibitors of HIV-1 reverse transcriptase through fragment screening.

scientific article published on 18 May 2015

Identification of residues involved in NS2 homodimerization and elucidation of their impact on the HCV life cycle

scientific article published on 30 August 2011

Impact of residues in the nonnucleoside reverse transcriptase inhibitor binding pocket on HIV-1 reverse transcriptase heterodimer stability

scientific article

Increasing prevalence of K65K and K66K in HIV-1 subtype B reverse transcriptase.

scientific article published on 24 September 2016

Infectious KoRV-related retroviruses circulating in Australian bats

scientific article published on 13 April 2020

Investigation of Topoisomerase Inhibitors for Activity against Human Immunodeficiency Virus: Inhibition by Coumermycin A1

Lactic Acid, a Vaginal Microbiota Metabolite, Elicits an Anti-inflammatory Response from Vaginal and Cervical Epithelial Cells

Long-term foscarnet therapy not associated with the development of foscarnet-resistant human immunodeficiency virus type 1 in an acquired immunodeficiency syndrome patient.

scientific article

Maturation of the HIV reverse transcription complex: putting the jigsaw together

scientific article

Mechanisms of inhibition of HIV replication by non-nucleoside reverse transcriptase inhibitors

scientific article

Modulation of the oligomeric structures of HIV-1 retroviral enzymes by synthetic peptides and small molecules

scientific article

Molecular dissection of an inhibitor targeting the HIV integrase dependent preintegration complex nuclear import

Mutations that abrogate human immunodeficiency virus type 1 reverse transcriptase dimerization affect maturation of the reverse transcriptase heterodimer

scientific article

N348I in HIV-1 reverse transcriptase counteracts the synergy between zidovudine and nevirapine

scientific article

N348I in HIV-1 reverse transcriptase decreases susceptibility to tenofovir and etravirine in combination with other resistance mutations

scientific article

N348I in reverse transcriptase provides a genetic pathway for HIV-1 to select thymidine analogue mutations and mutations antagonistic to thymidine analogue mutations

scientific article

N348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance

scientific article

No association between XMRV or related gammaretroviruses in Australian prostate cancer patients

scientific article published on 10 January 2013

Nonnucleoside Reverse Transcriptase Inhibitors Reduce HIV-1 Production from Latently Infected Resting CD4+ T Cells following Latency Reversal.

scientific article published on 19 December 2016

Nonnucleoside reverse transcriptase inhibitors are chemical enhancers of dimerization of the HIV type 1 reverse transcriptase

scientific article

Oxazole-benzenesulfonamide derivatives inhibit HIV-1 reverse transcriptase interaction with cellular eEF1A and reduce viral replication

scholarly article by Daniel J Rawle et al published 27 March 2019 in Journal of Virology

Phosphatidylethanolamine binding is a conserved feature of cyclotide-membrane interactions

scientific article

Potent nonnucleoside reverse transcriptase inhibitors target HIV-1 Gag-Pol

scientific article

Relationship between enzyme activity and dimeric structure of recombinant HIV-1 reverse transcriptase

article

Reverse transcriptase mutations in sequential HIV-1 isolates in a patient with AIDS.

scientific article published on July 1995

Role of RNase H Activity in NRTI/NNRTI Drug Resistance

Role of residues in the tryptophan repeat motif for HIV-1 reverse transcriptase dimerization

scientific article

SPL7013 Gel (VivaGel®) retains potent HIV-1 and HSV-2 inhibitory activity following vaginal administration in humans

scientific article (publication date: 2011)

Sensitive assessment of the virologic outcomes of stopping and restarting non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy

scientific article

Silent mutations at codons 65 and 66 in reverse transcriptase alleviate indel formation and restore fitness in subtype B HIV-1 containing D67N and K70R drug resistance mutations

scientific article

Structure activity relationship of dendrimer microbicides with dual action antiviral activity

scientific article (publication date: 23 August 2010)

Synergistic Inhibition of Human Immunodeficiency Virus Type 1 in vitro by Interferon Alpha and Coumermycin A1

Synergistic inhibition of human immunodefficiency virus type 1 in vitro by coumermycin A1 and human leukocyte interferon

scientific article published in 1991

Targeting Human Immunodeficiency Virus Type 1 Assembly, Maturation and Budding

The NRTIs lamivudine, stavudine and zidovudine have reduced HIV-1 inhibitory activity in astrocytes

scientific article

The effect of NNRTIs on HIV reverse transcriptase dimerization.

scientific article published on August 2003

The human immunodeficiency virus type 1 nonnucleoside reverse transcriptase inhibitor resistance mutation I132M confers hypersensitivity to nucleoside analogs

scientific article published on 04 February 2009

The implausible "in vivo" role of hydrogen peroxide as an antimicrobial factor produced by vaginal microbiota

scientific article published on 6 February 2018

The packaging and maturation of the HIV-1 Pol proteins

scientific article

The role of lactic acid production by probiotic Lactobacillus species in vaginal health

scientific article

The seventh (and last?) International Microbicides Conference: from discovery to delivery

scientific article

Ubisol-Aqua: coenzyme Q10 prevents antiretroviral toxic neuropathy in an in vitro model

scientific article published in April 2010

Vaginal Concentrations of Lactic Acid Potently Inactivate HIV-1 Compared to Short Chain Fatty Acids Present During Bacterial Vaginosis

Vaginal concentrations of lactic acid potently inactivate HIV

scientific article published on 08 May 2013

Virological significance, prevalence and genetic basis of hypersusceptibility to nonnucleoside reverse transcriptase inhibitors

scientific article

Virucidal activity of the dendrimer microbicide SPL7013 against HIV-1.

scientific article

Why Do We Need New Drug Classes for HIV Treatment and Prevention?

scientific article published on 13 October 2015

Zidovudine resistance is suppressed by mutations conferring resistance of human immunodeficiency virus type 1 to foscarnet.

scientific article published in October 1996

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