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List of works by Philipp F Lange

Active site specificity profiling of the matrix metalloproteinase family: Proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic peptide cleavage analyses.

scientific article published on 22 September 2015

Annotating N termini for the human proteome project: N termini and Nα-acetylation status differentiate stable cleaved protein species from degradation remnants in the human erythrocyte proteome

scientific article

ClC-7 requires Ostm1 as a beta-subunit to support bone resorption and lysosomal function

scientific journal article

Ensembles of protein termini and specific proteolytic signatures as candidate biomarkers of disease.

scientific article

HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development

scientific article published on 10 October 2017

Macrophage matrix metalloproteinase-12 dampens inflammation and neutrophil influx in arthritis

scientific article published on 9 October 2014

Modification of BRCA1-associated breast cancer risk by HMMR overexpression

scientific article published on 07 April 2022

Network analyses reveal pervasive functional regulation between proteases in the human protease web

scientific article (publication date: May 2014)

Novel matrix metalloproteinase inhibitor [18F]marimastat-aryltrifluoroborate as a probe for in vivo positron emission tomography imaging in cancer.

scientific article published on 20 August 2010

Origins and clinical relevance of proteoforms in pediatric malignancies

scientific article published on 18 February 2019

PDX models reflect the proteome landscape of pediatric acute lymphoblastic leukemia but divert in select pathways

scientific article published on 15 March 2021

Pathogenic BRCA1 variants disrupt PLK1-regulation of mitotic spindle orientation

scientific article published on 22 April 2022

Protein TAILS: when termini tell tales of proteolysis and function

scientific article

Proteome TopFIND 3.0 with TopFINDer and PathFINDer: database and analysis tools for the association of protein termini to pre- and post-translational events.

scientific article

Proteomic amino-termini profiling reveals targeting information for protein import into complex plastids

scientific article published on 16 September 2013

Robust unsupervised deconvolution of linear motifs characterizes 68 protein modifications at proteome scale

scientific article published on 18 November 2021

Sensitive Determination of Proteolytic Proteoforms in Limited Microscale Proteome Samples

scientific article published on 30 August 2019

TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors

scientific article published on 27 July 2016

TopFIND 2.0--linking protein termini with proteolytic processing and modifications altering protein function ⬇️

scientific article published on November 18, 2011

Tumor Variant Identification That Accounts for the Unique Molecular Landscape of Pediatric Malignancies

scientific article published on 01 October 2018

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