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List of works by Jean-Luc Balligand

"La Donna è Mobile...": is cardiac neuronal nitric oxide synthase such a disconcerting enzyme?

scientific article published on 01 December 2005

A Belgian consensus strategy to identify familial hypercholesterolaemia in the coronary care unit and its subsequent cascade screening and treatment: BEL-FaHST (The BELgium Familial Hypercholesterolaemia STrategy)

article

A cathepsin D-cleaved 16 kDa form of prolactin mediates postpartum cardiomyopathy.

scientific article published in February 2007

A specific method for measurement of nitric oxide synthase enzymatic activity in peritoneal biopsies

scientific article published on 01 January 2000

A-769662 potentiates the effect of other AMP-activated protein kinase activators on cardiac glucose uptake

scientific article published on 18 April 2014

AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation

scientific article

Activation of the cardiac mTOR/p70(S6K) pathway by leucine requires PDK1 and correlates with PRAS40 phosphorylation

scientific article published on 5 January 2010

Amiodarone liver toxicity about two cases and review of literature

scientific article published in May 2004

Amlodipine and stroke prevention

scientific article published on 06 August 2007

An integrative translational approach to study heart failure with preserved ejection fraction: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology

scientific article published on 16 November 2017

Beta-3 Adrenoceptors as New Therapeutic Targets for Cardiovascular Pathologies ⬇️

scientific article published on September 1, 2011

Beta-Catenin downregulation attenuates ischemic cardiac remodeling through enhanced resident precursor cell differentiation.

scholarly article

Beta3-Adrenoreceptors in Cardiovasular Diseases: New Roles for an “Old” Receptor ⬇️

scientific article published on February 1, 2013

Beta3-adrenergic receptors in cardiac and vascular tissues emerging concepts and therapeutic perspectives.

scientific article published on January 2010

Cardiac beta3-adrenergic receptors in the clinical arena: the end of the beginning

scientific article

Cardiac endothelium and tissue growth.

scientific article published on January 1997

Cardiac myocyte β3-adrenergic receptors prevent myocardial fibrosis by modulating oxidant stress-dependent paracrine signaling

scientific article

Cardiac salvage by tweaking with beta-3-adrenergic receptors.

scientific article published on 21 March 2016

Cardiomyocyte-restricted overexpression of endothelial nitric oxide synthase (NOS3) attenuates beta-adrenergic stimulation and reinforces vagal inhibition of cardiac contraction.

scientific article

Cardiovascular effects of beta 3-adrenoceptor stimulation in perinephritic hypertension.

scientific article published in August 2001

Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology

scientific article published on January 2011

Caveolin plays a central role in endothelial progenitor cell mobilization and homing in SDF-1-driven postischemic vasculogenesis

scientific journal article

Chronic β1-adrenergic blockade enhances myocardial β3-adrenergic coupling with nitric oxide-cGMP signaling in a canine model of chronic volume overload: new insight into mechanisms of cardiac benefit with selective β1-blocker therapy.

scientific article published on 6 December 2014

Clinical and biochemical data of endothelial function in Women Consuming Combined Contraceptives

scientific article

Contractile responsiveness of ventricular myocytes to isoproterenol is regulated by induction of nitric oxide synthase activity in cardiac microvascular endothelial cells in heterotypic primary culture

scientific article published on 01 September 1995

Control of cardiac muscle cell function by an endogenous nitric oxide signaling system ⬇️

scientific article published on January 1, 1993

Differential regulation of nitric oxide synthases and their allosteric regulators in heart and vessels of hypertensive rats

scientific article published on 01 February 2003

Does Early Mismatched Nutrition Predispose to Hypertension and Atherosclerosis, in Male Mice? ⬇️

scientific article published on September 9, 2010

Dyslipidaemia in type II diabetic mice does not aggravate contractile impairment but increases ventricular stiffness.

scientific article published on 14 August 2007

ESC Working Group on Myocardial Function Position Paper: how to study the right ventricle in experimental models

scientific article published on 23 February 2014

Editorial on « Stretch-induced compliance: a novel adaptive biological mechanism to acute cardiac load ».

scientific article published on 9 February 2018

Endothelial beta3-adrenoceptors mediate vasorelaxation of human coronary microarteries through nitric oxide and endothelium-dependent hyperpolarization.

scientific article

Endothelial beta3-adrenoreceptors mediate nitric oxide-dependent vasorelaxation of coronary microvessels in response to the third-generation beta-blocker nebivolol.

scientific article published in August 2005

Endothelial type nitric oxide synthase in skeletal muscle fibers: mitochondrial relationships

scientific article published on 01 June 1995

Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase

scientific article

Erythropoietin preserves the endothelial differentiation capacity of cardiac progenitor cells and reduces heart failure during anticancer therapies.

scientific article

Frequency-dependent activation of a constitutive nitric oxide synthase and regulation of contractile function in adult rat ventricular myocytes.

scientific article published in February 1996

Gene deletion of P2Y4 receptor lowers exercise capacity and reduces myocardial hypertrophy with swimming exercise.

scientific article published on 3 August 2012

Genetic deletion of aquaporin-1 results in microcardia and low blood pressure in mouse with intact nitric oxide-dependent relaxation, but enhanced prostanoids-dependent relaxation.

scientific article published on 20 July 2013

HMGCoA reductase inhibition reverses myocardial fibrosis and diastolic dysfunction through AMP-activated protein kinase activation in a mouse model of metabolic syndrome.

scientific article published on 29 March 2013

HYGIEIA: HYpothesizing the Genesis of Infectious Diseases and Epidemics through an Integrated Systems Biology Approach

scientific article published on 24 June 2022

Heat shock protein 90 in endothelial nitric oxide synthase signaling: following the lead(er)?

scientific article published on 01 May 2002

Heme-nitrosylated hemoglobin and oxidative stress in women consuming combined contraceptives. Clinical application of the EPR spectroscopy.

scientific article published on 6 April 2017

Hsp90 and caveolin are key targets for the proangiogenic nitric oxide-mediated effects of statins.

scientific article published in November 2001

Hypercholesterolemia in rats induces podocyte stress and decreases renal cortical nitric oxide synthesis via an angiotensin II type 1 receptor-sensitive mechanism

scientific article published in April 2004

Hypoleptinemia in patients with anorexia nervosa: loss of circadian rhythm and unresponsiveness to short-term refeeding.

scientific article

Increased prostaglandin-D2 in male STAT3-deficient hearts shifts cardiac progenitor cells from endothelial to white adipocyte differentiation

scientific article published on 28 December 2020

Induction of nitric oxide synthase activity by cytokines in ventricular myocytes is necessary but not sufficient to decrease contractile responsiveness to beta-adrenergic agonists

scientific article published on 01 September 1995

Inflammation as a therapeutic target in heart failure? A scientific statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology

scientific article published on February 2009

Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide

scientific article published on 01 October 2020

Interaction of the heart and its close and distant neighbours: report of the Meeting of the ESC Working Groups Myocardial Function and Cellular Biology

scientific article published on 16 July 2013

Involvement of nitric oxide in iodine deficiency-induced microvascular remodeling in the thyroid gland: role of nitric oxide synthase 3 and ryanodine receptors

scientific article

KLF6 orchestrates cardiac myocyte-to-fibroblast communication: 'He who has ears to hear, let him hear'.

scientific article

Letter by Balligand and Michel Regarding Article, "Adrenergic Receptors in Individual Ventricular Myocytes: the Beta-1 and Alpha-1B Are in All Cells, the Alpha-1A Is in a Subpopulation, and the Beta-2 and Beta-3 Are Mostly Absent".

scientific article

Living Donor Liver Transplantation in Children: Surgical and Immunological Results in 250 Recipients at Université Catholique de Louvain

scientific article

Loss of Mouse P2Y6 Nucleotide Receptor Is Associated with Physiological Macrocardia and Amplified Pathological Cardiac Hypertrophy.

scientific article published on 26 May 2016

Loss of mouse P2Y4 nucleotide receptor protects against myocardial infarction through endothelin-1 downregulation.

scientific article

Low-density lipoprotein-cholesterol-induced endothelial dysfunction and oxidative stress: the role of statins

scientific article published on 28 September 2013

MRI Assessment of Cardiomyopathy Induced by β1-Adrenoreceptor Autoantibodies and Protection Through β3-Adrenoreceptor Overexpression.

scientific article published on 09 March 2017

Management of familial hypercholesterolemia in children and young adults: consensus paper developed by a panel of lipidologists, cardiologists, paediatricians, nutritionists, gastroenterologists, general practitioners and a patient organization.

scientific article published on 17 June 2011

Mice that lack endothelial nitric oxide synthase are protected against functional and structural modifications induced by acute peritonitis.

scientific article published in December 2003

Moderate caveolin-1 downregulation prevents NADPH oxidase-dependent endothelial nitric oxide synthase uncoupling by angiotensin II in endothelial cells

scientific article published on 09 June 2011

Modulation of cardiac contraction, relaxation and rate by the endothelial nitric oxide synthase (eNOS): lessons from genetically modified mice.

scientific article

Molecular networks in Network Medicine: Development and applications

scientific article published on 19 April 2020

Myocardial contractile dysfunction in the systemic inflammatory response syndrome: role of a cytokine-inducible nitric oxide synthase in cardiac myocytes.

scientific article published on January 1995

Nebivolol exerts beneficial effects on endothelial function, early endothelial progenitor cells, myocardial neovascularization, and left ventricular dysfunction early after myocardial infarction beyond conventional β1-blockade

scientific article published on 01 February 2011

Nebivolol prevents desensitization of β-adrenoceptor signaling and induction of cardiac hypertrophy in response to isoprenaline beyond β1-adrenoceptor blockage

scientific article published on 01 March 2013

New and Emerging Therapies and Targets: Beta-3 Agonists.

scientific article published on 30 December 2016

Nitric oxide and cardiac function.

scientific article published on September 1996

Nitric oxide and the heart: update on new paradigms.

scientific article

Nitric oxide signalling in cardiovascular health and disease.

scientific article published in February 2018

Nitric oxide synthase (NOS3)-mediated cholinergic modulation of Ca2+ current in adult rabbit atrioventricular nodal cells.

scientific article published in June 1996

Nitric oxide synthase and cyclic GMP signaling in cardiac myocytes: From contractility to remodeling ⬇️

scientific article published on 07 August 2011

Nitric oxide synthase in post-ischaemic remodelling: new pathways and mechanisms.

scientific article published on 06 January 2012

Nitric oxide synthase isoforms play distinct roles during acute peritonitis.

scientific article published on 25 August 2009

Nitric oxide synthases and cardiac muscle. Autocrine and paracrine influences.

scientific article published on October 1997

Nitric oxide-dependent parasympathetic signaling is due to activation of constitutive endothelial (type III) nitric oxide synthase in cardiac myocytes

scientific article published on 01 June 1995

Nitrosyl-hemoglobin formation in rodent and human venous erythrocytes reflects NO formation from the vasculature in vivo

scientific article published on 11 July 2018

Nitrosylated hemoglobin levels in human venous erythrocytes correlate with vascular endothelial function measured by digital reactive hyperemia

scientific article

P2Y(4) nucleotide receptor: a novel actor in post-natal cardiac development.

scientific article published on 22 March 2012

PKD1 haploinsufficiency is associated with altered vascular reactivity and abnormal calcium signaling in the mouse aorta.

scientific article

Paracrine nitric oxide induces expression of cardiac sarcomeric proteins in adult progenitor cells through soluble guanylyl cyclase/cyclic-guanosine monophosphate and Wnt/β-catenin inhibition

scientific article published on 12 August 2016

Protein kinase G type I in cardiac myocytes: unmasked at last? ⬇️

scientific article published on December 23, 2011

Rationale and design of a multicentre, randomized, placebo-controlled trial of mirabegron, a Beta3-adrenergic receptor agonist on left ventricular mass and diastolic function in patients with structural heart disease Beta3-left ventricular hypertroph

Real-time RT-PCR for the detection of beta-adrenoceptor messenger RNAs in small human endomyocardial biopsies.

scientific article

Recent advances in the understanding of the role of nitric oxide in cardiovascular homeostasis.

scientific article

Reduced scar maturation and contractility lead to exaggerated left ventricular dilation after myocardial infarction in mice lacking AMPKα1.

scientific article

Reducing damage through Nrf-2 ⬇️

scientific article published on August 22, 2013

Regulation of cardiac myocyte contractile function by inducible nitric oxide synthase (iNOS): mechanisms of contractile depression by nitric oxide

scientific article published on 01 February 1998

Regulation of cytokine-inducible nitric oxide synthase in cardiac myocytes and microvascular endothelial cells. Role of extracellular signal-regulated kinases 1 and 2 (ERK1/ERK2) and STAT1 alpha

scientific article published on 01 January 1996

Regulation of the mammalian heart function by nitric oxide.

scientific article

Relevance of nitric oxide for myocardial remodeling.

scientific article published on March 2007

Reversible S-nitrosation of creatine kinase by nitric oxide in adult rat ventricular myocytes

scientific article published on 01 May 1998

RhoA activation and interaction with Caveolin-1 are critical for pressure-induced myogenic tone in rat mesenteric resistance arteries.

scientific article published on 10 November 2006

Role of caveolar compartmentation in endothelium-derived hyperpolarizing factor-mediated relaxation: Ca2+ signals and gap junction function are regulated by caveolin in endothelial cells

scientific article published on 11 February 2008

Role of nitric oxide and oxidative stress in a sheep model of persistent atrial fibrillation

scientific article published on 17 February 2013

Role of nitric oxide in parasympathetic modulation of beta-adrenergic myocardial contractility in normal dogs

scientific article

Rosuvastatin decreases caveolin-1 and improves nitric oxide-dependent heart rate and blood pressure variability in apolipoprotein E-/- mice in vivo.

scientific article published on 28 April 2003

Rosuvastatin increases vascular endothelial PPARgamma expression and corrects blood pressure variability in obese dyslipidaemic mice.

scientific article published on 6 December 2007

Rosuvastatin restores superoxide dismutase expression and inhibits accumulation of oxidized LDL in the aortic arch of obese dyslipidemic mice.

scientific article published on 26 March 2007

Sepsis is associated with an upregulation of functional beta3 adrenoceptors in the myocardium.

scientific article published on 19 November 2007

Sodium-myoinositol cotransporter-1, SMIT1, mediates the production of reactive oxygen species induced by hyperglycemia in the heart

scientific article published on 27 January 2017

Statins and hypertension.

scientific article

Studying the Role of AMPK in Cardiac Hypertrophy and Protein Synthesis.

scientific article published in January 2018

Targeting myocardial remodelling to develop novel therapies for heart failure: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology

scientific article

The Function and Therapeutic Potential of Long Non-coding RNAs in Cardiovascular Development and Disease

scientific article published on 28 July 2017

The calcium channel blocker amlodipine promotes the unclamping of eNOS from caveolin in endothelial cells.

scientific article published on 27 April 2006

The innate immune system in chronic cardiomyopathy: a European Society of Cardiology (ESC) scientific statement from the Working Group on Myocardial Function of the ESC.

scientific article published on 15 January 2018

The negative inotropic effect of beta3-adrenoceptor stimulation is mediated by activation of a nitric oxide synthase pathway in human ventricle.

scientific article published on October 1998

The regulation of endothelial nitric oxide synthase by caveolin: a paradigm validated in vivo and shared by the 'endothelium-derived hyperpolarizing factor'.

scientific article published on 26 March 2010

The role of the NO pathway in the control of cardiac function.

scientific article

Towards a re-definition of 'cardiac hypertrophy' through a rational characterization of left ventricular phenotypes: a position paper of the Working Group 'Myocardial Function' of the ESC.

scientific article published on 27 June 2011

Transgenic mice for real-time visualization of cGMP in intact adult cardiomyocytes.

scientific article published on 5 March 2014

Treatments targeting inotropy

scientific article published on 01 November 2019

Variability of Mouse Left Ventricular Function Assessment by 11.7 Tesla MRI.

scientific article

Vasodilatory Mechanisms of Beta Receptor Blockade ⬇️

scientific article published on August 1, 2012

Vitamin B or L-arginine supplementation in hyperhomocysteinaemia: think twice!: EXPERT'S PERSPECTIVE ⬇️

scientific article published on 09 August 2012

beta(3)-Adrenoceptor stimulation on top of beta(1)-adrenoceptor blockade "Stop or Encore?".

scientific article published in April 2009

eNOS activation by physical forces: from short-term regulation of contraction to chronic remodeling of cardiovascular tissues.

scientific article published on April 2009

β-Adrenergic Receptors Cooperate With Transcription Factors: The "STAT" of Their Union

scientific article published on 01 December 2015

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