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List of works by Hideo Kimura

3-Mercaptopyruvate sulfurtransferase produces hydrogen sulfide and bound sulfane sulfur in the brain

scientific journal article

A mechanism of retinal protection from light-induced degeneration by hydrogen sulfide ⬇️

scientific article published on March 1, 2012

A novel mechanism for the regulation of amyloid precursor protein metabolism

scientific article

Abnormal lipid metabolism in cystathionine beta-synthase-deficient mice, an animal model for hyperhomocysteinemia.

scientific article published on 4 October 2004

Absence of association between codon 129/219 polymorphisms of the prion protein gene and Alzheimer's disease in Japan.

scientific article published in October 2003

Alternative pathway of H2S and polysulfides production from sulfurated catalytic-cysteine of reaction intermediates of 3-mercaptopyruvate sulfurtransferase

scientific article published on 10 January 2018

Amyloid beta-protein activates tachykinin receptors and inositol trisphosphate accumulation by synergy with glutamate ⬇️

scientific article published on August 15, 1993

Amyloid peptides are toxic via a common oxidative mechanism

scientific article

Analysis of endogenous H2S and H2Sn in mouse brain by high-performance liquid chromatography with fluorescence and tandem mass spectrometric detection

scientific article published on 18 October 2017

Antagonistic action of 6-aminomethyl-3-methyl-4H, 1,2,4-benzothiadiazine-1, 1-dioxide (TAG), and evidence for a transmitter role of taurine in stellate interneurons in the cerebellum

scientific article published on 01 January 1983

Association study of the chemokine, CXC motif, ligand 1 (CXCL1) gene with sporadic Alzheimer's disease in a Japanese population.

scientific article published on 25 January 2005

CYP2C8 haplotype structures and their influence on pharmacokinetics of paclitaxel in a Japanese population

scientific article published on 01 July 2007

Complementary DNA cloning of cytochrome P-450s related to P-450(M-1) from the complementary DNA library of female rat livers. Predicted primary structures for P-450f, PB-1, and PB-1-related protein with a bizarre replacement block and their mode of

scholarly article

Cystathionine beta-synthase, a key enzyme for homocysteine metabolism, is preferentially expressed in the radial glia/astrocyte lineage of developing mouse CNS

scientific journal article

Determination of oxidized and reduced nicotinamide adenine dinucleotide in cell monolayers using a single extraction procedure and a spectrophotometric assay.

scientific article published on March 2005

Development of a reversible fluorescent probe for reactive sulfur species, sulfane sulfur, and its biological application.

scientific article published on 3 January 2017

Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST) Targeting Active-site Cysteine Persulfide

scientific article (publication date: 12 January 2017)

Dock3 induces axonal outgrowth by stimulating membrane recruitment of the WAVE complex

scientific article

Effects of Taurine and GABA on Ca spikes and Na spikes in cerebellar Purkinje cells in vitro: Intrasomatic study ⬇️

scientific article published on February 7, 1983

Eleven Novel Single Nucleotide Polymorphisms in the NRH2 (PXR) Gene, Pour of which Induce Non-synonymous Amino Acid Alterations

article

Evidence for taurine as an inhibitory neurotransmitter in cerebellar stellate interneurons: selective antagonism by TAG (6-aminomethyl-3-methyl-4H,1,2,4-benzothiadiazine-1,1-dioxide)

scientific article published on 01 April 1983

Five novel single nucleotide polymorphisms in the EPHX1 gene encoding microsomal epoxide hydrolase

scientific article published on 01 January 2003

Functional characterization of five novel CYP2C8 variants, G171S, R186X, R186G, K247R, and K383N, found in a Japanese population.

scientific article published on 16 February 2005

Genetic association study on in and around the APOE in late-onset Alzheimer disease in Japanese.

scientific article

Growth factors and vitamin E modify neuronal glutamate toxicity ⬇️

scientific article published on September 1, 1992

H2S2014 in Kyoto: the 3rd International Conference on H2S in Biology and Medicine

scientific article published on 14 October 2014

Haplotype structures of EPHX1 and their effects on the metabolism of carbamazepine-10,11-epoxide in Japanese epileptic patients.

scientific article published on 4 February 2005

Haplotypes of CYP3A4 and their close linkage with CYP3A5 haplotypes in a Japanese population.

scientific article published in January 2004

Hydrogen Sulfide and Polysulfide Signaling

scientific article

Hydrogen polysulfide (H2S n ) signaling along with hydrogen sulfide (H2S) and nitric oxide (NO).

scientific article

Hydrogen sulfide and polysulfides as biological mediators.

scientific article published on 9 October 2014

Hydrogen sulfide and polysulfides as signaling molecules

scientific article

Hydrogen sulfide as a biological mediator

scientific article published on 01 May 2005

Hydrogen sulfide as a neuromodulator.

scientific article

Hydrogen sulfide as a physiological mediator: its function and therapeutic applications ⬇️

scientific article published on 01 December 2010

Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function

scientific article

Hydrogen sulfide enhances reducing activity in neurons: neurotrophic role of H2S in the brain?

scientific article published on November 2007

Hydrogen sulfide induces calcium waves in astrocytes.

scientific article

Hydrogen sulfide induces cyclic AMP and modulates the NMDA receptor.

scientific article published on January 2000

Hydrogen sulfide is a novel prosecretory neuromodulator in the Guinea-pig and human colon.

scientific article published on 18 August 2006

Hydrogen sulfide is produced by cystathionine γ-lyase at the steady-state low intracellular Ca(2+) concentrations

scientific article published on 10 January 2013

Hydrogen sulfide signaling in the central nervous system -Comparison with nitric oxide

scientific article published on 29 August 2020

Hydrogen sulfide: its production and functions

article

Hydrogen sulfide: production, release, and functions ⬇️

scientific article published on 01 January 2012

Identification of H2S3 and H2S produced by 3-mercaptopyruvate sulfurtransferase in the brain

scientific article

Inhaled hydrogen sulfide prevents endotoxin-induced systemic inflammation and improves survival by altering sulfide metabolism in mice.

scientific article published in July 2012

Ionic mechanisms of the action of taurine on cerebellar Purkinje cell dendrites in vitro: intradendritic study.

scientific article published in February 1983

Isolation and characterization of novel presenilin binding protein

scientific article (publication date: July 2000)

Lack of association between TrkA single nucleotide polymorphisms and sporadic Alzheimer's disease in a Japanese population.

scientific article

Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction.

scientific article

Metabolic turnover of hydrogen sulfide.

scientific article published on 18 April 2012

Miniature synaptic potentials recorded intracellularly from Purkinje cell dendrites in guinea pig cerebellar slices.

scientific article

Murine cystathionine gamma-lyase: complete cDNA and genomic sequences, promoter activity, tissue distribution and developmental expression

scientific journal article

Nutritional essentiality of sulfur in health and disease.

scientific article published on 24 May 2013

Pharmacological evidence for L-aspartate as the neurotransmitter of cerebellar climbing fibres in the guinea-pig.

scientific article published in August 1985

Pharmacological evidence for taurine as an inhibitory neurotransmitter in the cerebellum.

scientific article

Physiological Roles of Hydrogen Sulfide and Polysulfides.

scientific article published on January 2015

Physiological functions of hydrogen sulfide (H2S) and its therapeutic applications

scientific article published on February 1, 2013

Physiological role of hydrogen sulfide and polysulfide in the central nervous system.

scientific article published on 11 September 2013

Physiological roles of hydrogen sulfide and polysulfides

scientific article published on 01 January 2016

Polysulfide evokes acute pain through the activation of nociceptive TRPA1 in mouse sensory neurons.

scientific article published on 2 May 2015

Polysulfide exerts a protective effect against cytotoxicity caused by t-buthylhydroperoxide through Nrf2 signaling in neuroblastoma cells.

scientific article published on 18 September 2013

Polysulfide promotes neuroblastoma cell differentiation by accelerating calcium influx

scientific article

Presenilin-binding protein forms aggresomes in monkey kidney COS-7 cells.

scientific article published in August 2002

Production and physiological effects of hydrogen sulfide.

scientific article published on 25 May 2013

Production of hydrogen sulfide from d-cysteine and its therapeutic potential.

scientific article published on 16 July 2013

Schwannoma-derived growth factor must be transported into the nucleus to exert its mitogenic activity.

scientific article

Schwannoma-derived growth factor promotes the neuronal differentiation and survival of PC12 cells ⬇️

scientific article published on February 1, 1992

Signaling by hydrogen sulfide (H2S) and polysulfides (H2Sn) in the central nervous system

scientific article published on 06 March 2019

Signaling molecules: hydrogen sulfide and polysulfide

scientific article

Signaling of hydrogen sulfide and polysulfides

scientific article published on 9 October 2014

Signalling by hydrogen sulfide and polysulfides via protein S-sulfuration

scientific article published on 04 March 2019

Six novel nonsynonymous CYP1A2 gene polymorphisms: catalytic activities of the naturally occurring variant enzymes.

scientific article published on 16 October 2003

Substratum-growth factor collaborations are required for the mitogenic activities of activin and FGF on embryonal carcinoma cells.

scientific article published on August 1991

Sulfite protects neurons from oxidative stress

scientific article published on 01 July 2018

Taurine-induced increase of the Cl-conductance of cerebellar Purkinje cell dendrites in vitro

scientific article published on 01 January 1983

The neurophysiology of hydrogen sulfide.

scientific article published on April 2011

The physiological role of hydrogen sulfide and beyond

scientific article published on February 2014

The possible role of hydrogen sulfide as an endogenous neuromodulator.

scientific article published in February 1996

The possible role of hydrogen sulfide as an endogenous smooth muscle relaxant in synergy with nitric oxide.

scientific article

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