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List of works by Nathan J. Palpant

A transcribed enhancer dictates mesendoderm specification in pluripotency

scientific article

Artificial selection for whole animal low intrinsic aerobic capacity co-segregates with hypoxia-induced cardiac pump failure

scientific article

Cardiac development in zebrafish and human embryonic stem cells is inhibited by exposure to tobacco cigarettes and e-cigarettes

scientific article published on 15 May 2015

Cardiopoietry in motion: primed mesenchymal stem cells for ischemic cardiomyopathy.

scientific article published on 10 April 2013

Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis

scientific article published on August 2017

Diastolic dysfunction and thin filament dysregulation resulting from excitation-contraction uncoupling in a mouse model of restrictive cardiomyopathy.

scientific article

Evidence for Minimal Cardiogenic Potential of Stem Cell Antigen 1-Positive Cells in the Adult Mouse Heart

Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells

scientific article published on December 2016

Genetic Lineage Tracing of Sca-1+ Cells Reveals Endothelial but Not Myogenic Contribution to the Murine Heart

scientific article published on 01 December 2018

Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts.

scientific article

Inducible CRISPR genome editing platform in naive human embryonic stem cells reveals JARID2 function in self-renewal.

scientific article published on 22 February 2018

Influence of genetic background on ex vivo and in vivo cardiac function in several commonly used inbred mouse strains

scientific article

Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes

scientific article

Methods for assessing the electromechanical integration of human pluripotent stem cell-derived cardiomyocyte grafts.

scientific article

Molecular cardiology in translation: gene, cell and chemical-based experimental therapeutics for the failing heart.

scientific article published on December 2008

Nkx2.5 marks angioblasts that contribute to hemogenic endothelium of the endocardium and dorsal aorta.

scientific article

Organization of gene programs revealed by unsupervised analysis of diverse gene–trait associations

scientific article published in 2022

Pathogenic peptide deviations support a model of adaptive evolution of chordate cardiac performance by troponin mutations.

scientific article

Proliferation at the heart of preadolescence

scientific article published on 01 May 2014

Reprogramming the injured heart

scientific article published in Nature

Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells

scientific article published on 05 March 2021

Single histidine-substituted cardiac troponin I confers protection from age-related systolic and diastolic dysfunction.

scientific article published on 16 July 2008

Single-Cell Transcriptomic Analysis of Cardiac Differentiation from Human PSCs Reveals HOPX-Dependent Cardiomyocyte Maturation

scientific article published on 01 October 2018

Single-cell RNA-seq of human induced pluripotent stem cells reveals cellular heterogeneity and cell state transitions between subpopulations

scientific article published on 11 May 2018

Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development

scientific article published on 16 June 2015

Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species

scientific article

Targeted genomic integration of a selectable floxed dual fluorescence reporter in human embryonic stem cells

scientific article

The developmental origins and lineage contributions of endocardial endothelium

scientific article published on 29 January 2016

Zinc finger nucleases: looking toward translation.

scientific article published on 09 February 2012

pH-responsive titratable inotropic performance of histidine-modified cardiac troponin I.

scientific article published on 3 April 2012