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List of works by Sofie Celen

Clinical validation of the novel HDAC6 radiotracer [18F]EKZ-001 in the human brain

scientific article published on 08 July 2020

Comparison of New Tau PET-Tracer Candidates With [18F]T808 and [18F]T807

scientific article

Development and biological evaluation of ⁹⁹mTc-sulfonamide derivatives for in vivo visualization of CA IX as surrogate tumor hypoxia markers

scientific article published on 30 October 2013

Efficient purification and metabolite analysis of radiotracers using high-performance liquid chromatography and on-line solid-phase extraction.

scientific article published in November 2007

Fatty Acid Amide Hydrolase Inhibition by JNJ-42165279: A Multiple-Ascending Dose and a Positron Emission Tomography Study in Healthy Volunteers

scientific article published on 25 March 2018

Kinetic modeling and long-term test-retest reproducibility of the mGluR5 PET tracer 18F-FPEB in human brain

scientific article published on 21 January 2016

PET radioligands for in vivo visualization of neuroinflammation.

scientific article

Preclinical Evaluation and Quantification of 18F-FPEB as a Radioligand for PET Imaging of the Metabotropic Glutamate Receptor 5.

scientific article published on 24 September 2015

Preclinical evaluation of 18F-JNJ41510417 as a radioligand for PET imaging of phosphodiesterase-10A in the brain.

scientific article published on 16 September 2010

Preclinical evaluation of [(18)F]JNJ42259152 as a PET tracer for PDE10A

scientific article published on 09 May 2013

Quantification of 18F-JNJ-42259152, a novel phosphodiesterase 10A PET tracer: kinetic modeling and test-retest study in human brain.

scientific article published on 10 July 2013

Quantification of TSPO overexpression in a rat model of local neuroinflammation induced by intracerebral injection of LPS by the use of [(18)F]DPA-714 PET.

scientific article published in September 2015

Striatal phosphodiesterase 10A availability is altered secondary to chronic changes in dopamine neurotransmission

scientific article published on 21 March 2016

Synthesis and biological evaluation of (11)C-labeled beta-galactosyl triazoles as potential PET tracers for in vivo LacZ reporter gene imaging.

scientific article

Synthesis and biological evaluation of carbon-11 and fluorine-18 labeled tracers for in vivo visualization of PDE10A.

scientific article published on 24 May 2014

Synthesis and preclinical evaluation of [11C]MA-PB-1 for in vivo imaging of brain monoacylglycerol lipase (MAGL).

scientific article published on 25 April 2017

Synthesis of [18F]RGD-K5 by catalyzed [3 + 2] cycloaddition for imaging integrin αvβ3 expression in vivo

scientific article published in July 2013

Synthesis, In Vivo Occupancy, and Radiolabeling of Potent Phosphodiesterase Subtype-10 Inhibitors as Candidates for Positron Emission Tomography Imaging

scientific article published on August 2, 2011

Synthesis, evaluation, and radiolabeling of new potent positive allosteric modulators of the metabotropic glutamate receptor 2 as potential tracers for positron emission tomography imaging

scientific article published on 11 October 2012

Toward waste-free production of Heck products with a catalytic palladium system under oxygen

scientific article published on 01 August 2003

Translation of HDAC6 PET Imaging Using [18F]EKZ-001-cGMP Production and Measurement of HDAC6 Target Occupancy in Nonhuman Primates

scientific article published on 19 March 2020

What We Observe In Vivo Is Not Always What We See In Vitro: Development and Validation of 11C-JNJ-42491293, A Novel Radioligand for mGluR2.

scientific article published on 28 July 2016

[18F]JNJ42259152 binding to phosphodiesterase 10A, a key regulator of medium spiny neuron excitability, is altered in the presence of cyclic AMP.

scientific article published on 24 September 2016

cGMP production of the radiopharmaceutical [18 F]MK-6240 for PET imaging of human neurofibrillary tangles

scientific article published on 9 February 2017