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List of works by Gary C Sieck

1α,25-Dihydroxyvitamin D3 Regulates Mitochondrial Oxygen Consumption and Dynamics in Human Skeletal Muscle Cells

scientific article

1α,25-dihydroxyvitamin D3 mitigates cancer cell mediated mitochondrial dysfunction in human skeletal muscle cells.

scientific article published on 20 January 2018

A new technique for acute and chronic recording of crural diaphragm EMG in cats

scientific article published on 01 April 1982

A novel and selective poly (ADP-ribose) polymerase inhibitor ameliorates chemotherapy-induced painful neuropathy

scientific article

A novel approach for targeted delivery to motoneurons using cholera toxin-B modified protocells.

scientific article published on 15 September 2016

A study of ion binding in the hemolymph of Periplaneta americana ⬇️

scientific article published on January 1, 1977

ATP consumption rate per cross bridge depends on myosin heavy chain isoform.

scientific article published on 14 February 2003

Absence of high-frequency oscillations in the discharge of pneumotaxic neurons in intact, unanesthetized cats.

scientific article published in September 1981

Adapt or Perish.

scientific article published in July 2015

Adaptations of diaphragm neuromuscular junction following inactivity.

scientific article published on January 1995

Age-related changes in diaphragm muscle contractile properties and myosin heavy chain isoforms

scientific article published on 01 July 1994

Ageing and neurotrophic signalling effects on diaphragm neuromuscular function

scientific article published in December 2014

Aging-related changes in respiratory system mechanics and morphometry in mice

scientific article published on 10 June 2016

Agonist-induced cyclic ADP ribose production in airway smooth muscle.

scientific article published on 30 June 2006

Airway hyperresponsiveness: from molecules to bedside

scientific article published on 01 July 2003

Analysis of fluid movement in skeletal muscle using fluorescent microspheres

scientific article published on 2 February 2016

Analysis of muscle fiber clustering in the diaphragm muscle of sarcopenic mice

scientific article published on June 2015

Application of the Cavalieri Principle in Volume Estimation Using Laser Confocal Microscopy ⬇️

scientific article published on November 1, 1994

Asthma and sarcoplasmic reticulum Ca2+ reuptake in airway smooth muscle.

scientific article published on October 2009

BDNF effects on functional recovery across motor behaviors after cervical spinal cord injury

scientific article published on 9 November 2016

Breathing: Motor Control of Diaphragm Muscle.

scientific article published in March 2018

Cardiac arrhythmias induced by transient hypertension during sleep-waking states.

scientific article published in July 1983

Cardiovascular effects of levosimendan during rewarming from hypothermia in rat.

scientific article

Caveolae targeting and regulation of large conductance Ca(2+)-activated K+ channels in vascular endothelial cells.

scientific article published on 23 January 2005

Caveolin-1 regulation of store-operated Ca2+influx in human airway smooth muscle ⬇️

scientific article published on January 12, 2012

Changes in actomyosin ATP consumption rate in rat diaphragm muscle fibers during postnatal development.

scientific article

Changes in diaphragmatic EMG spectra during hyperpneic loads

Chronic TrkB agonist treatment in old age does not mitigate diaphragm neuromuscular dysfunction

scientific article published on January 2017

Chronic aminophylline administration. Effect on diaphragm contractility and fatigue resistance in vitro

scientific article published on 01 July 1991

Chronic assessment of diaphragm muscle EMG activity across motor behaviors ⬇️

scientific article published on March 15, 2011

Cigarette smoke-induced mitochondrial fragmentation and dysfunction in human airway smooth muscle.

scientific article

Communicating with Our External and Internal Environments ⬇️

scientific article published on 01 August 2012

Compensatory effects following unilateral diaphragm paralysis.

scientific article published on 5 August 2017

Congestive heart failure: differential adaptation of the diaphragm and latissimus dorsi ⬇️

scientific article published on August 1, 1995

Convergence of pattern generator outputs on a common mechanism of diaphragm motor unit recruitment

scientific article published on January 2014

Correlation of respiratory activity of contralateral diaphragm muscles for evaluation of recovery following hemiparesis.

scientific article published on January 2009

Cross-bridge cycling kinetics, actomyosin ATPase activity and myosin heavy chain isoforms in skeletal and smooth respiratory muscles

scientific article published on 01 March 1998

Cross-bridge kinetics in respiratory muscles.

scientific article published on September 1997

CrossTalk opposing view: The diaphragm muscle does not atrophy as a result of inactivity

scientific article published on 01 November 2013

Cyclic nucleotide regulation of store-operated Ca2+ influx in airway smooth muscle.

scientific article

Cytoskeletal remodeling slows cross-bridge cycling and ATP hydrolysis rates in airway smooth muscle

scientific article published on 01 August 2020

Denervation-induced changes in myosin heavy chain expression in the rat diaphragm muscle.

scientific article published on 18 April 2003

Design principles for life

scientific article published on 01 December 2012

Design principles for life

scientific article published on 01 January 2013

Development of Sinus Arrhythmia During Sleeping and Waking States in Normal Infants

scientific article published on September 1, 1978

Diaphragm dysfunction in chronic obstructive pulmonary disease.

scientific article published on 22 April 2005

Diaphragm electromyographic activity following unilateral midcervical contusion injury in rats.

scientific article published on 9 November 2016

Diaphragm mechanics in dogs with unilateral emphysema.

scientific article

Diaphragm motor unit recruitment in rats.

scientific article

Diaphragm muscle fiber function and structure in humans with hemidiaphragm paralysis.

scientific article published on 27 May 2011

Diaphragm muscle sarcopenia in Fischer 344 and Brown Norway rats.

scientific article published on 29 April 2016

Discharge correlations between neurons in the nucleus parabrachialis medialis during sleep-waking states

scientific article published on 01 October 1980

Discharge of neurons in the parabrachial pons related to the cardiac cycle: changes during different sleep-waking states

scientific article published on 01 October 1980

Discontinued stimulation of cardiomyocytes provides protection against hypothermia/rewarming - induced disruption of excitation-contraction coupling

scientific article published on 31 March 2018

Distribution of major basic protein on human airway following in vitro eosinophil incubation.

scientific article

EMG-based detection of inspiration in the rat diaphragm muscle.

scientific article published in January 2006

Effect of collagen digestion on the passive elastic properties of diaphragm muscle in rat.

scientific article

Effect of denervation on ATP consumption rate of diaphragm muscle fibers.

scientific article published on 7 June 2007

Effect of halothane on cADP-ribose-induced Ca(2+) release system in tracheal smooth muscle.

scientific article published in October 2002

Effect of mechanical ventilation on the diaphragm

scientific article published on 01 March 2008

Effect of proinflammatory cytokines on regulation of sarcoplasmic reticulum Ca2+ reuptake in human airway smooth muscle

scientific article published on 24 April 2009

Effects of antenatal lipopolysaccharide and postnatal hyperoxia on airway reactivity and remodeling in a neonatal mouse model

scientific article published on 5 November 2015

Effects of hypothyroidism on maximum specific force in rat diaphragm muscle fibers.

scientific article published in April 2002

Effects of milrinone on left ventricular cardiac function during cooling in an intact animal model

article

Effects of the inflammatory cytokines TNF-α and IL-13 on stromal interaction molecule-1 aggregation in human airway smooth muscle intracellular Ca(2+) regulation

scientific article published on October 2013

Effects of volatile anesthetics on store-operated Ca(2+) influx in airway smooth muscle.

scientific article

Elevated blood pressure and cardiac hypertrophy after ablation of the gly96/IEX-1 gene

scientific journal article

Endothelium-dependent effects of estrogen on vasomotor tone. Consequences of nongenomic actions.

scientific article published in February 2002

Endovascular treatment of experimental aneurysms by use of fibroblast-coated platinum coils: an angiographic and histopathologic study.

scientific article

Estrogen modification of feeding behavior in the female rat: influence of metabolic state

scientific article published on December 1, 1978

Exploring how cells communicate.

scientific article published in May 2013

F-actin stabilization increases tension cost during contraction of permeabilized airway smooth muscle in dogs

scientific article published on 01 September 1999

Feasibility and reliability of quantifying passive muscle stiffness in young children by using shear wave ultrasound elastography.

scientific article

Fiber type composition of muscle units in the cat diaphragm.

scientific article published in February 1989

Foreword to special issue: spinal cord injury-neuroplasticity and recovery of respiratory function

scientific article published on 11 September 2009

Functional Effects of Cigarette Smoke-Induced Changes in Airway Smooth Muscle Mitochondrial Morphology.

scientific article published on 30 July 2016

Functional Measurement of Respiratory Muscle Motor Behaviors Using Transdiaphragmatic Pressure.

scientific article published on January 2016

Functional impact of diaphragm muscle sarcopenia in both male and female mice

scientific article published in May 2015

Functional impact of sarcopenia in respiratory muscles

scientific article published on 11 October 2015

Functional recovery after cervical spinal cord injury: Role of neurotrophin and glutamatergic signaling in phrenic motoneurons.

scientific article

Gender and Relaxation to C-Type Natriuretic Peptide in Porcine Coronary Arteries ⬇️

scientific article published on July 1, 1998

Gender-related differences in proliferative responses of vascular smooth muscle cells to endothelin-1.

scientific article published in January 2001

Genetic models in applied physiology

scientific article published on 01 April 2003

Growth-related alterations in motor endplates of type-identified diaphragm muscle fibres

scientific article published on 01 March 1995

Heterogeneity in dynamic regulation of intracellular calcium in airway smooth muscle cells

scientific article published on July 1, 1997

Heterogeneous glutamatergic receptor mRNA expression across phrenic motor neurons in rats

scientific article published on 28 September 2019

Human diaphragm remodeling associated with chronic obstructive pulmonary disease: clinical implications.

scientific article published on 11 July 2003

Hypothermia/rewarming disrupts excitation-contraction coupling in cardiomyocytes.

scientific article published on 18 March 2016

Impact of diaphragm muscle fiber atrophy on neuromotor control.

scientific article published on 02 July 2013

Impact of glutamatergic and serotonergic neurotransmission on diaphragm muscle activity after cervical spinal hemisection.

scientific article

Impact of sarcopenia on diaphragm muscle fatigue

scientific article published on 22 April 2019

Impact of unilateral denervation on transdiaphragmatic pressure.

scientific article published on 29 January 2015

Inflammation alters regional mitochondrial Ca2+ in human airway smooth muscle cells ⬇️

scientific article published on June 6, 2012

Inflammation, caveolae and CD38-mediated calcium regulation in human airway smooth muscle.

scientific article published on 22 November 2013

Integrative and adaptive responses.

scientific article published on January 2015

Interaction between endoplasmic/sarcoplasmic reticulum stress (ER/SR stress), mitochondrial signaling and Ca(2+) regulation in airway smooth muscle (ASM)

scientific article

Intracellular signaling pathways regulating net protein balance following diaphragm muscle denervation.

scientific article

Invited review: Mechanisms underlying motor unit plasticity in the respiratory system.

scientific article

Isotonic force modulates force redevelopment rate of intact frog muscle fibres: evidence for cross-bridge induced thin filament activation

scientific article published on 01 September 2002

K(Ca)3.1 channels facilitate K+ secretion or Na+ absorption depending on apical or basolateral P2Y receptor stimulation

scientific article published on 23 May 2011

Key aspects of phrenic motoneuron and diaphragm muscle development during the perinatal period.

scientific article published on 10 April 2008

Life at the extreme: physiological adaptation.

scientific article published in March 2015

Living a healthier lifestyle.

scientific article published on September 2014

Living under extreme conditions.

scientific article published in November 2014

Localized delivery of brain-derived neurotrophic factor-expressing mesenchymal stem cells enhances functional recovery following cervical spinal cord injury

scientific article

Logarithmic superposition of force response with rapid length changes in relaxed porcine airway smooth muscle.

scientific article published on 3 September 2010

Lung edema clearance: 20 years of progress

scientific article published on 01 October 2002

Measurements of motoneuron somal volumes using laser confocal microscopy: comparisons with shape-based stereological estimations.

scientific article published on September 1993

Mechanical properties of respiratory muscles

scientific article published on October 2013

Mechanism of endothelial dysfunction in apolipoprotein E-deficient mice.

scientific article published in June 2001

Mechanisms of intrinsic force in small human airways.

scientific article

Mechanisms underlying greater sensitivity of neonatal cardiac muscle to volatile anesthetics.

scientific article published in April 2002

Mechanisms underlying hypothermia-induced cardiac contractile dysfunction.

scientific article published on 18 December 2009

Mechanisms underlying myosin heavy chain expression during development of the rat diaphragm muscle.

scientific article published on 27 July 2006

Metabolic variability within individual fibres of the cat tibialis posterior and diaphragm muscles

scientific article published on 01 August 1991

Mitochondrial Dysfunction in Airway Disease

scientific article published on 21 March 2017

Molecular biology of thermoregulation

scientific article published on 01 April 2002

Motoneuron BDNF/TrkB signaling enhances functional recovery after cervical spinal cord injury.

scientific article published on 10 April 2013

Motoneuron glutamatergic receptor expression following recovery from cervical spinal hemisection

scientific article

Muscle dysfunction in COPD

scientific article published on 07 February 2013

Muscle weakness in critical illness.

scientific article published in May 2015

Myosin filament polymerization and depolymerization in a model of partial length adaptation in airway smooth muscle.

scientific article published on 9 June 2011

Neuregulin-dependent protein synthesis in C2C12 myotubes and rat diaphragm muscle

scientific article published on 21 June 2006

Neuregulin‐1 at synapses on phrenic motoneurons ⬇️

scientific article published on October 15, 2010

Neuromotor control in chronic obstructive pulmonary disease ⬇️

scientific article published on January 17, 2013

Neuromuscular adaptations to respiratory muscle inactivity.

scientific article published on 08 September 2009

Neuromuscular transmission failure during postnatal development ⬇️

scientific article published on April 15, 1991

Neurotrophins improve neuromuscular transmission in the adult rat diaphragm.

scientific article published in March 2004

Nocturnal feeding pattern in the prepubertal rat: influence of the ventromedial hypothalamus (VMH)

scientific article published on October 1, 1979

Non-random distribution and sensory functions of primary cilia in vascular smooth muscle cells.

scientific article published on 16 May 2008

Non-stationarity and power spectral shifts in EMG activity reflect motor unit recruitment in rat diaphragm muscle ⬇️

scientific article published on September 7, 2012

Novel method for physiological recruitment of diaphragm motor units after upper cervical spinal cord injury.

scientific article published on 23 July 2009

On the terminology for describing the length-force relationship and its changes in airway smooth muscle

scientific article published in December 2004

Organ blood flow and O transport during hypothermia (27°C) and rewarming in a pig model

scientific article published on 02 December 2018

Oxandrolone enhances skeletal muscle myosin synthesis and alters global gene expression profile in Duchenne muscular dystrophy.

scientific article published in November 2005

Oxygen sensing in health and disease.

scientific article published on January 2004

Paradoxical use of tumor necrosis factor in treating pulmonary edema.

scientific article published in September 2014

Pasteurella haemolytica leukotoxin and endotoxin induced cytokine gene expression in bovine alveolar macrophages requires NF-kappaB activation and calcium elevation

scientific article published on 01 May 1999

Periodicities in physiological activity at puberty in the female rat ⬇️

scientific article published on September 1, 1978

Phrenic motoneuron expression of serotonergic and glutamatergic receptors following upper cervical spinal cord injury ⬇️

scientific article published on December 29, 2011

Phrenic motoneuron structural plasticity across models of diaphragm muscle paralysis

scientific article published on 08 November 2018

Phrenic motor unit recruitment during ventilatory and non-ventilatory behaviors ⬇️

scientific article published on 06 July 2011

Physiology in Perspective: Aging and Underlying Pathophysiology

scientific article published on 01 January 2017

Physiology in Perspective: Fulfilling the Promise of Tissue Engineering

scientific article published in January 2016

Physiology in Perspective: Homeostasis and Evolution

scientific article published on 01 March 2017

Physiology in Perspective: Homeostasis and Survival.

scientific article published in March 2018

Physiology in Perspective: Physiological Transitions During Our Lifespan.

scientific article published in July 2016

Physiology in Perspective: Physiology Provides Insight into Health.

scientific article published in November 2017

Physiology in Perspective: Pursuing the Enchanted Loom of Motor Control

scientific article published in March 2016

Physiology in Perspective: Sensing Our Environment Triggers Physiological and Evolutionary Adaptation

scientific article published on 01 May 2016

Physiology in Perspective: Stem Cells and Regenerative Physiology.

scientific article published in January 2018

Physiology in Perspective: The Air We Breathe: Providing O2 for Survival.

scientific article

Physiology in Perspective: The Body's Tubes Sustain Life but Underlie Disease.

scientific article

Physiology in Perspective: The Importance of Integrative Physiology

scientific article published on 01 May 2017

Physiology in Perspective: The Value of Integrative Physiology.

scientific article

Physiology in Perspective: We Learn From Evolutionary/Comparative Physiology

scientific article published on 01 November 2016

Physiology in Perspective: Why Do We Continue to Ignore Sex Differences?

scientific article published on 01 November 2015

Physiology in perspective: adaptive responses: changing to survive

scientific article published on 01 May 2014

Physiology in perspective: addressing cardiovascular health and disease.

scientific article published in July 2013

Physiology in perspective: cell migration and the regenerative process

scientific article published in November 2013

Physiology in perspective: the burden of obesity.

scientific article published on March 2014

Physiology in perspective: the life we take for granted.

scientific article

Physiology of aging

scientific article published on 01 October 2003

Physiology's impact: discovering life

scientific article

Physiology's impact: discovering life

scientific article published on 01 July 2013

Physiology's impact: stop ignoring the obvious-sex matters!

scientific article published on 01 January 2014

Physiology: a world perspective.

scientific article

Pkd2+/- vascular smooth muscles develop exaggerated vasocontraction in response to phenylephrine stimulation

scientific article published on 03 January 2007

Pneumotaxic area neuronal discharge during sleep-waking states in the cat

scientific article published on 01 January 1980

Positive end-expiratory airway pressure does not aggravate ventilator-induced diaphragmatic dysfunction in rabbits

scientific article

Postnatal Changes in the Distribution of Succinate Dehydrogenase Activities among Diaphragm Muscle Fibers

scientific article published on June 1, 1991

Prepubertal cyclicity in feeding behavior and body weight regulation in the female rat

scientific article published on February 1, 1977

Prolonged C2 spinal hemisection-induced inactivity reduces diaphragm muscle specific force with modest, selective atrophy of type IIx and/or IIb fibers

scientific article published on 29 November 2012

Promoting a central role for physiology in research and education worldwide

scientific article published on 01 December 2010

Puberty-related alterations in the organization of sleep-wakefulness states: Differences between spontaneous and induced pubertal conditions ⬇️

scientific article published on September 1, 1978

Quantifying passive muscle stiffness in children with and without cerebral palsy using ultrasound shear wave elastography

scientific article published on 4 July 2016

Quantitative determination of calcium-activated myosin adenosine triphosphatase activity in rat skeletal muscle fibres

scientific article published on July 1, 1992

Rebuttal from Gary C. Sieck and Carlos B. Mantilla

scientific article published on 01 November 2013

Recruitment of rat diaphragm motor units across motor behaviors with different levels of diaphragm activation

scientific article

Reduced ribosomal protein s6 phosphorylation after progressive resistance exercise in growing adolescent rats

scientific article

Regulation of feeding behavior in the prepubertal female rat ⬇️

scientific article published on November 1, 1978

Regulation of sarcoplasmic reticulum Ca2+ reuptake in porcine airway smooth muscle.

scientific article

Regulation of store-operated Ca2+ entry by CD38 in human airway smooth muscle.

scientific article published on 4 January 2008

Respiratory muscle coordination in acute spinal dogs

scientific article published on 01 April 1996

Respiratory muscle plasticity

scientific article published on 01 April 2012

Respiratory-related heart rate variation during sleep and waking states in cats

scientific article published on 01 April 1981

Response to letter by Dr. Marc Hershenson (exposure of airway smooth muscle cells to cigarette smoke extract).

scientific article published on August 2014

Retrograde labeling of phrenic motoneurons by intrapleural injection

scientific article published on 24 June 2009

Role of TrkB kinase activity in aging diaphragm neuromuscular junctions

scientific article

Role of superoxide ion formation in hypothermia/rewarming induced contractile dysfunction in cardiomyocytes

scientific article published on 16 February 2018

Role of the endothelial caveolae microdomain in shear stress-mediated coronary vasorelaxation.

scientific article published on 18 September 2017

Safety factor for neuromuscular transmission at type-identified diaphragm fibers.

scientific article published in June 2007

Semi-automated assessment of transdiaphragmatic pressure variability across motor behaviors

scientific article published on 21 May 2015

Sleep-wakefulness changes at the time of puberty in the female rat.

scientific article

Sodium-Calcium Exchange in Intracellular Calcium Handling of Human Airway Smooth Muscle ⬇️

scientific article published on August 15, 2011

Spatial and temporal aspects of ACh-induced [Ca2+]i oscillations in porcine tracheal smooth muscle

scientific article published on 01 March 2000

Store-operated Ca2+ entry in porcine airway smooth muscle.

scientific article published on 14 November 2003

Subcellular localization of cyclic ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activities in porcine airway smooth muscle

scientific article published on 01 October 2000

Susceptibility of HLA DR3 transgenic mice to experimental autoimmune myasthenia gravis.

scientific article published in May 1998

Synaptic vesicle cycling at type-identified diaphragm neuromuscular junctions

scientific article published on 01 December 2004

Synaptic vesicle distribution and release at rat diaphragm neuromuscular junctions

scientific article published on 09 May 2007

Synaptic vesicle pools at diaphragm neuromuscular junctions vary with motoneuron soma, not axon terminal, inactivity.

scientific article published on 7 March 2007

Systems biology of skeletal muscle: fiber type as an organizing principle ⬇️

scientific article published on July 18, 2012

TNFα decreases mitochondrial movement in human airway smooth muscle.

scientific article

TNFα enhances force generation in airway smooth muscle

scientific article published on 6 April 2017

Targeted delivery of TrkB receptor to phrenic motoneurons enhances functional recovery of rhythmic phrenic activity after cervical spinal hemisection.

scientific article

The Impact of Midcervical Contusion Injury on Diaphragm Muscle Function.

scientific article published on 28 September 2015

The physiologic responses to epinephrine during cooling and after rewarming in vivo ⬇️

scientific article published on September 23, 2011

The role of cyclic-ADP-ribose-signaling pathway in oxytocin-induced Ca2+ transients in human myometrium cells.

scientific article published on 16 October 2003

Transforming medicine through physiology

scientific article published on 01 May 2015

TrkB gene therapy by adeno-associated virus enhances recovery after cervical spinal cord injury

scientific article

TrkB kinase activity is critical for recovery of respiratory function after cervical spinal cord hemisection.

scientific article

Type I procollagen production and cell proliferation is mediated by transforming growth factor-beta in a model of hepatic fibrosis

scientific article published on 01 May 1996

Uptake and intracellular fate of cholera toxin subunit b-modified mesoporous silica nanoparticle-supported lipid bilayers (aka protocells) in motoneurons

scientific article published on 12 January 2018

Volume measurements in confocal microscopy

scientific article published on 01 January 1999

Wireless Instantaneous Neurotransmitter Concentration System-based amperometric detection of dopamine, adenosine, and glutamate for intraoperative neurochemical monitoring

scientific article

[Ca2+]i reduction increases cellular proliferation and apoptosis in vascular smooth muscle cells: relevance to the ADPKD phenotype

scientific journal article

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