List of works - Chae Hun Leem

A Novel Nicotinamide Adenine Dinucleotide Correction Method for Intracellular Ca2+ Measurement with Fura-2-Analog in Live Cells

scientific article published on 20 September 2019

A Novel Nicotinamide Adenine Dinucleotide Correction Method for Mitochondrial Ca(2+) Measurement with FURA-2-FF in Single Permeabilized Ventricular Myocytes of Rat.

scientific article published on 30 June 2015

A computational model of cytosolic and mitochondrial [ca] in paced rat ventricular myocytes.

scientific article

A mathematical model of pacemaker activity recorded from mouse small intestine.

scientific article published in May 2006

A new integrated method for analyzing heart mechanics using a cell-hemodynamics-autonomic nerve control coupled model of the cardiovascular system.

scientific article published on 11 August 2007

A new multi-scale simulation model of the circulation: from cells to system.

scientific article published in June 2006

A novel hypothesis for the binding mode of HERG channel blockers

scientific article published on 31 March 2006

Analysis of factors affecting Ca(2+)-dependent inactivation dynamics of L-type Ca(2+) current of cardiac myocytes in pulmonary vein of rabbit

scientific article published on 06 June 2012

Anthropometry-based estimation of body heat capacity in individuals aged 7-69 years: the Size Korea Survey 2010.

scientific article published on 6 February 2018

Aorta-to-arm pulse wave transit time ratio: Better prediction of coronary artery disease and stroke than pulse wave velocity.

scientific article published on 24 November 2015

Body composition and personality traits in so-Yang type males

scientific article

Body temperature regulation: Sasang typology-based perspective.

scientific article published on 17 August 2015

Body weight difference between dual-energy X-ray absorptiometry and multi-frequency bioelectrical impedance analysis attenuates the equivalence of body-composition assessment

scientific article published on 18 April 2018

Cardiac inotropy, lusitropy, and Ca2+ handling with major metabolic substrates in rat heart

scientific article

Cell-cell contacts via N-cadherin induce a regulatory renin secretory phenotype in As4.1 cells

scientific article published in 2022

Characterization of intracellular pH regulation in the guinea-pig ventricular myocyte.

scientific article published in May 1999

Computational analysis of the quaternary structural changes induced by point mutations in human UDP-glucose dehydrogenase.

scientific article published on 7 April 2009

Corrigendum to "Aorta-to-arm pulse wave transit time ratio: Better prediction of coronary artery disease and stroke than pulse wave velocity" [204 (2016), 1-3].

scientific article published on 10 May 2016

Coupled Ca2+/H+ transport by cytoplasmic buffers regulates local Ca2+ and H+ ion signaling

scientific article published on 15 May 2013

Effects of an intracellular Ca(2+) chelator on insulin resistance and hypertension in high-fat-fed rats and spontaneously hypertensive rats.

scientific article published in March 2004

Effects of streptozotocin and unilateral nephrectomy on L-type Ca²⁺ channels and membrane capacitance in arteriolar smooth muscle cells.

scientific article published on 9 September 2014

Effects of thyroid hormone on the calcium current and isoprenaline-induced background current in rabbit ventricular myocytes

scientific article published on 01 July 1994

Experimental generation and computational modeling of intracellular pH gradients in cardiac myocytes

scientific article

Expression of stem cell markers in primo vessel of rat

scientific article published on 31 July 2013

Impaired Inactivation of L-Type Ca2+ Current as a Potential Mechanism for Variable Arrhythmogenic Liability of HERG K+ Channel Blocking Drugs

scientific article

Implication of phosphorylation of the myosin II regulatory light chain in insulin-stimulated GLUT4 translocation in 3T3-F442A adipocytes

scientific article published on April 2006

Improvement of insulin sensitivity by chelation of intracellular Ca(2+) in high-fat-fed rats.

scientific article

In silico models for evaluating proarrhythmic risk of drugs

scientific article published on 04 June 2020

Intracellular osmotic gradient generation in rat ventricle myocyte by using a micro-perfusion system

scientific article published on 17 November 2006

Involvement of vesicular H+-ATPase in insulin-stimulated glucose transport in 3T3-F442A adipocytes

scientific article published on 7 September 2007

Koreans Do Not Have Higher Percent Body Fat than Australians: Implication for the Diagnosis of Obesity in Asians

scientific article published on 29 September 2019

Lower cellular metabolic power can be an explanation for obesity trend in Tae-Eum type: hypothesis and clinical observation

scientific article published on 8 July 2017

Modeling of arrhythmogenic automaticity induced by stretch in rat atrial myocytes.

scientific article published on 31 October 2008

Modeling of stochastic behavior of pacemaker potential in interstitial cells of Cajal.

scientific article published on 17 September 2014

Modelling Cl- homeostasis and volume regulation of the cardiac cell.

scientific article published in May 2006

Neuronal nitric oxide synthase modulation of intracellular Ca2+ handling overrides fatty acid potentiation of cardiac inotropy in hypertensive rats

scientific article published on 22 May 2017

New index for categorising cardiac reentrant wave: in silico evaluation

scientific article published on 01 September 2011

Novel Anthropometry-Based Calculation of the Body Heat Capacity in the Korean Population.

scientific article published on 3 November 2015

Out-of-equilibrium pH transients in the guinea-pig ventricular myocyte

scientific article published on 01 June 1998

Personalized metabolic profile estimations using oral glucose tolerance tests.

scientific article published on 23 August 2014

Perspectives of physiome research

scientific article published on 5 January 2016

Potassium currents in isolated deiters' cells of Guinea pig.

scientific article

Pulmonary Function Difference in Sasang Constitutional Types.

scientific article

Pumping Ca2+ up H+ gradients: a Ca2(+)-H+ exchanger without a membrane.

scientific article published on 10 February 2014

Relationship of the Cold-Heat Sensation of the Limbs and Abdomen with Physiological Biomarkers.

scientific article published on 12 October 2016

Reply to readers' comment on "Body weight difference between dual-energy X-ray absorptiometry and multi-frequency bioelectrical impedance analysis attenuates the equivalence of body composition assessment"

scientific article published on 20 February 2019

Role of Stretch-activated Channels in the Heart: Action Potential and Ca(2+) Transients ⬇️

scientific article published on February 4, 2011

Role of stretch-activated channels on the stretch-induced changes of rat atrial myocytes

scientific article

Sarcolemmal mechanisms for pHi recovery from alkalosis in the guinea-pig ventricular myocyte

scientific article published on 01 June 1998

Seasonal effects on resting energy expenditure are dependent on age and percent body fat

scientific article published on 28 May 2019

Simulation of Ca2+-activated Cl- current of cardiomyocytes in rabbit pulmonary vein: implications of subsarcolemmal Ca2+ dynamics

scientific article published in May 2006

Simulation of spontaneous action potentials of cardiomyocytes in pulmonary veins of rabbits

scientific article published on 11 August 2007

Special issue on "Toward physiome based therapeutics".

scientific article published in September 2014

Stretch-activated currents in cardiomyocytes isolated from rabbit pulmonary veins.

scientific article

Taeeum-type people in Sasang constitutional medicine have a reduced mitochondrial metabolism.

scientific article

Teaching cardiac excitation-contraction coupling using a mathematical computer simulation model of human ventricular myocytes

scientific article published on 01 September 2020

The effect of taurine on the activation osmolality of the osmosensitive current in single ventricular myocytes of rabbits

scientific article published on 01 March 1996

The ion channel activator CyPPA inhibits melanogenesis via the GSK3β/β-catenin pathway

scientific article published on 28 December 2018

Thermoregulatory Responses to Graded Exercise Differ among Sasang Types.

scientific article published on 2 June 2015

Three-Dimensional Heart Model-Based Screening of Proarrhythmic Potential by in silico Simulation of Action Potential and Electrocardiograms

scientific article published on 04 September 2019

Toward a grey box approach for cardiovascular physiome

scientific article published on 26 August 2019

Vesicular transport as a new paradigm in short-term regulation of transepithelial transport.

scientific article

List of works by Chae Hun Leem

A Novel Nicotinamide Adenine Dinucleotide Correction Method for Intracellular Ca2+ Measurement with Fura-2-Analog in Live Cells

A Novel Nicotinamide Adenine Dinucleotide Correction Method for Mitochondrial Ca(2+) Measurement with FURA-2-FF in Single Permeabilized Ventricular Myocytes of Rat.

A computational model of cytosolic and mitochondrial [ca] in paced rat ventricular myocytes.

A mathematical model of pacemaker activity recorded from mouse small intestine.

A new integrated method for analyzing heart mechanics using a cell-hemodynamics-autonomic nerve control coupled model of the cardiovascular system.

A new multi-scale simulation model of the circulation: from cells to system.

A novel hypothesis for the binding mode of HERG channel blockers

Analysis of factors affecting Ca(2+)-dependent inactivation dynamics of L-type Ca(2+) current of cardiac myocytes in pulmonary vein of rabbit

Anthropometry-based estimation of body heat capacity in individuals aged 7-69 years: the Size Korea Survey 2010.

Aorta-to-arm pulse wave transit time ratio: Better prediction of coronary artery disease and stroke than pulse wave velocity.

Body composition and personality traits in so-Yang type males

Body temperature regulation: Sasang typology-based perspective.

Body weight difference between dual-energy X-ray absorptiometry and multi-frequency bioelectrical impedance analysis attenuates the equivalence of body-composition assessment

Cardiac inotropy, lusitropy, and Ca2+ handling with major metabolic substrates in rat heart

Cell-cell contacts via N-cadherin induce a regulatory renin secretory phenotype in As4.1 cells

Characterization of intracellular pH regulation in the guinea-pig ventricular myocyte.

Computational analysis of the quaternary structural changes induced by point mutations in human UDP-glucose dehydrogenase.

Corrigendum to "Aorta-to-arm pulse wave transit time ratio: Better prediction of coronary artery disease and stroke than pulse wave velocity" [204 (2016), 1-3].

Coupled Ca2+/H+ transport by cytoplasmic buffers regulates local Ca2+ and H+ ion signaling

Effects of an intracellular Ca(2+) chelator on insulin resistance and hypertension in high-fat-fed rats and spontaneously hypertensive rats.

Effects of streptozotocin and unilateral nephrectomy on L-type Ca²⁺ channels and membrane capacitance in arteriolar smooth muscle cells.

Effects of thyroid hormone on the calcium current and isoprenaline-induced background current in rabbit ventricular myocytes

Experimental generation and computational modeling of intracellular pH gradients in cardiac myocytes

Expression of stem cell markers in primo vessel of rat

Impaired Inactivation of L-Type Ca2+ Current as a Potential Mechanism for Variable Arrhythmogenic Liability of HERG K+ Channel Blocking Drugs

Implication of phosphorylation of the myosin II regulatory light chain in insulin-stimulated GLUT4 translocation in 3T3-F442A adipocytes

Improvement of insulin sensitivity by chelation of intracellular Ca(2+) in high-fat-fed rats.

In silico models for evaluating proarrhythmic risk of drugs

Intracellular osmotic gradient generation in rat ventricle myocyte by using a micro-perfusion system

Involvement of vesicular H+-ATPase in insulin-stimulated glucose transport in 3T3-F442A adipocytes

Koreans Do Not Have Higher Percent Body Fat than Australians: Implication for the Diagnosis of Obesity in Asians

Lower cellular metabolic power can be an explanation for obesity trend in Tae-Eum type: hypothesis and clinical observation

Modeling of arrhythmogenic automaticity induced by stretch in rat atrial myocytes.

Modeling of stochastic behavior of pacemaker potential in interstitial cells of Cajal.

Modelling Cl- homeostasis and volume regulation of the cardiac cell.

Neuronal nitric oxide synthase modulation of intracellular Ca2+ handling overrides fatty acid potentiation of cardiac inotropy in hypertensive rats

New index for categorising cardiac reentrant wave: in silico evaluation

Novel Anthropometry-Based Calculation of the Body Heat Capacity in the Korean Population.

Out-of-equilibrium pH transients in the guinea-pig ventricular myocyte

Personalized metabolic profile estimations using oral glucose tolerance tests.

Perspectives of physiome research

Potassium currents in isolated deiters' cells of Guinea pig.

Pulmonary Function Difference in Sasang Constitutional Types.

Pumping Ca2+ up H+ gradients: a Ca2(+)-H+ exchanger without a membrane.

Relationship of the Cold-Heat Sensation of the Limbs and Abdomen with Physiological Biomarkers.

Reply to readers' comment on "Body weight difference between dual-energy X-ray absorptiometry and multi-frequency bioelectrical impedance analysis attenuates the equivalence of body composition assessment"

Role of Stretch-activated Channels in the Heart: Action Potential and Ca(2+) Transients ⬇️

Role of stretch-activated channels on the stretch-induced changes of rat atrial myocytes

Sarcolemmal mechanisms for pHi recovery from alkalosis in the guinea-pig ventricular myocyte

Seasonal effects on resting energy expenditure are dependent on age and percent body fat

Simulation of Ca2+-activated Cl- current of cardiomyocytes in rabbit pulmonary vein: implications of subsarcolemmal Ca2+ dynamics

Simulation of spontaneous action potentials of cardiomyocytes in pulmonary veins of rabbits

Special issue on "Toward physiome based therapeutics".

Stretch-activated currents in cardiomyocytes isolated from rabbit pulmonary veins.

Taeeum-type people in Sasang constitutional medicine have a reduced mitochondrial metabolism.

Teaching cardiac excitation-contraction coupling using a mathematical computer simulation model of human ventricular myocytes

The effect of taurine on the activation osmolality of the osmosensitive current in single ventricular myocytes of rabbits

The ion channel activator CyPPA inhibits melanogenesis via the GSK3β/β-catenin pathway

Thermoregulatory Responses to Graded Exercise Differ among Sasang Types.

Three-Dimensional Heart Model-Based Screening of Proarrhythmic Potential by in silico Simulation of Action Potential and Electrocardiograms

Toward a grey box approach for cardiovascular physiome

Vesicular transport as a new paradigm in short-term regulation of transepithelial transport.