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List of works by Ornella Cuomo

A critical role for the potassium-dependent sodium-calcium exchanger NCKX2 in protection against focal ischemic brain damage.

scientific article

A new cell-penetrating peptide that blocks the autoinhibitory XIP domain of NCX1 and enhances antiporter activity

scientific article

Antithrombin reduces ischemic volume, ameliorates neurologic deficits, and prolongs animal survival in both transient and permanent focal ischemia.

scientific article

Conjunctival instillation of plasminogen eliminates ocular lesion in B6.129P2-Plgtm1Jld transgenic mice, a model of ligneous conjunctivitis ⬇️

scientific article published on May 16, 2013

Involvement of the potassium-dependent sodium/calcium exchanger gene product NCKX2 in the brain insult induced by permanent focal cerebral ischemia.

scientific article published in March 2007

Ionic homeostasis in brain conditioning

scientific article

Ischemic tolerance modulates TRAIL expression and its receptors and generates a neuroprotected phenotype.

scientific article

MicroRNA-103-1 selectively downregulates brain NCX1 and its inhibition by anti-miRNA ameliorates stroke damage and neurological deficits

scientific article published on 23 June 2014

NCX1 Exchanger Cooperates with Calretinin to Confer Preconditioning-Induced Tolerance Against Cerebral Ischemia in the Striatum

scientific article

NCX1 and NCX3: two new effectors of delayed preconditioning in brain ischemia.

scientific article published on 17 October 2011

Neurounina-1, a novel compound that increases Na+/Ca2+ exchanger activity, effectively protects against stroke damage

scientific article

Oligosaccharidic fractions derived from Triticum vulgare extract accelerate tissutal repairing processes in in vitro and in vivo models of skin lesions

scientific article published on 8 November 2014

Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic bra

scientific article published on 5 May 2015

Proteolysis of AKAP121 regulates mitochondrial activity during cellular hypoxia and brain ischaemia

scientific journal article

Proteolytic control of neurite outgrowth inhibitor NOGO-A by the cAMP/PKA pathway.

scientific article

Sp3/REST/HDAC1/HDAC2 Complex Represses and Sp1/HIF-1/p300 Complex Activates ncx1 Gene Transcription, in Brain Ischemia and in Ischemic Brain Preconditioning, by Epigenetic Mechanism.

scientific article

Targeted acetylation of NF-kappaB/RelA and histones by epigenetic drugs reduces post-ischemic brain injury in mice with an extended therapeutic window.

scientific article

Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage

scientific article published in January 2008

The NCX3 isoform of the Na+/Ca2+ exchanger contributes to neuroprotection elicited by ischemic postconditioning.

scientific article published on 14 July 2010

The antiepileptic drug levetiracetam suppresses non-convulsive seizure activity and reduces ischemic brain damage in rats subjected to permanent middle cerebral artery occlusion

scientific article (publication date: 2013)

Triticum vulgare extract exerts an anti-inflammatory action in two in vitro models of inflammation in microglial cells.

scientific article

Two sodium/calcium exchanger gene products, NCX1 and NCX3, play a major role in the development of permanent focal cerebral ischemia.

scientific article published on 7 October 2004

nNOS and p-ERK involvement in the neuroprotection exerted by remote postconditioning in rats subjected to transient middle cerebral artery occlusion ⬇️

scientific article published on February 27, 2013

ncx1, ncx2, and ncx3 gene product expression and function in neuronal anoxia and brain ischemia.

scientific article published on March 2007

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