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List of works by Paolo Ambrosino

A new Italian FHM2 family: clinical aspects and functional analysis of the disease-associated mutation

scientific article

Activation and desensitization of TRPV1 channels in sensory neurons by the PPARα agonist palmitoylethanolamide ⬇️

scientific article published on March 1, 2013

Characterization of two de novoKCNT1 mutations in children with malignant migrating partial seizures in infancy

scientific article published on 16 January 2016

Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons.

scientific article

Early-onset epileptic encephalopathy caused by gain-of-function mutations in the voltage sensor of Kv7.2 and Kv7.3 potassium channel subunits.

scientific article

Epilepsy-causing mutations in Kv7.2 C-terminus affect binding and functional modulation by calmodulin.

scientific article published on 12 June 2015

Expression and function of Kv7.4 channels in rat cardiac mitochondria: possible targets for cardioprotection.

scientific article published on 29 December 2015

Functional and biochemical interaction between PPARα receptors and TRPV1 channels: Potential role in PPARα agonists-mediated analgesia.

scientific article published on 8 July 2014

Genotype-phenotype correlations in neonatal epilepsies caused by mutations in the voltage sensor of K(v)7.2 potassium channel subunits

scientific article published on 25 February 2013

Isoxazole derivatives as potent transient receptor potential melastatin type 8 (TRPM8) agonists

scientific article published on 20 September 2013

Molecular pathophysiology and pharmacology of the voltage-sensing module of neuronal ion channels

scientific article

Molecular pharmacology of the amiloride analog 3-amino-6-chloro-5-[(4-chloro-benzyl)amino]-n-[[(2,4-dimethylbenzyl)-amino]iminomethyl]-pyrazinecarboxamide (CB-DMB) as a pan inhibitor of the Na+-Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in stably

scientific article published on 14 July 2009

Neuronal potassium channel openers in the management of epilepsy: role and potential of retigabine.

scientific article published on 7 December 2010

Neurounina-1, a novel compound that increases Na+/Ca2+ exchanger activity, effectively protects against stroke damage

scientific article

Neutralization of a unique, negatively-charged residue in the voltage sensor of K V 7.2 subunits in a sporadic case of benign familial neonatal seizures

scientific article published on April 2009

Novel KCNQ2 and KCNQ3 mutations in a large cohort of families with benign neonatal epilepsy: first evidence for an altered channel regulation by syntaxin-1A.

scientific article published on 13 January 2014

Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic bra

scientific article published on 5 May 2015

T-type channel blocking properties and antiabsence activity of two imidazo[1,2-b]pyridazine derivatives structurally related to indomethacin.

scientific article

The Voltage-Sensing Domain of K(v)7.2 Channels as a Molecular Target for Epilepsy-Causing Mutations and Anticonvulsants.

scientific article published on February 2011

The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels

scientific article

The ever changing moods of calmodulin: how structural plasticity entails transductional adaptability.

scientific article published on 22 May 2014

Towards the realization of label-free biosensors through impedance spectroscopy integrated with IDES technology

scientific article published on 12 January 2012

Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators

article

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