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List of works by Gebhard Schertler

7 Å resolution in protein two-dimensional-crystal X-ray diffraction at Linac Coherent Light Source

scientific article

A three-dimensional movie of structural changes in bacteriorhodopsin

scientific article

Adaptation of pineal expressed teleost exo-rod opsin to non-image forming photoreception through enhanced Meta II decay.

scientific article

Addendum to “Three-dimensional mass density mapping of cellular ultrastructure by ptychographic X-ray nanotomography” [J. Struct. Biol. 192 (2015) 461–469]

An alpha-carbon template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors 1 1Edited by R. Huber ⬇️

scientific article published on September 12, 1997

Arrangement of rhodopsin transmembrane α-helices

scientific article published in Nature

Arrestin-1 engineering facilitates complex stabilization with native rhodopsin

scientific article published in Scientific Reports

Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor

scientific article published on 3 February 2016

Batch crystallization of rhodopsin for structural dynamics using an X-ray free-electron laser

scientific article published on 27 June 2015

Characterisation of an improved two-dimensional p22121 crystal from bovine rhodopsin.

scientific article

Complete Reversible Refolding of a G-Protein Coupled Receptor on a Solid Support

scientific article

Conformational Selection in a Protein-Protein Interaction Revealed by Dynamic Pathway Analysis

scientific article published on 23 December 2015

Conformational activation of visual rhodopsin in native disc membranes

scientific article published on 10 March 2015

Conserved activation pathways in G-protein-coupled receptors

scientific article published on April 2012

Constitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 binding

scientific article published on 17 July 2013

Convergent evolution of tertiary structure in rhodopsin visual proteins from vertebrates and box jellyfish.

scientific article published on 23 May 2018

Cryo-EM structure of the rhodopsin-Gαi-βγ complex reveals binding of the rhodopsin C-terminal tail to the gβ subunit

scientific article published on 28 June 2019

Crystal structure of jumping spider rhodopsin-1 as a light sensitive GPCR

scientific article published on 27 June 2019

Crystal structure of rhodopsin in complex with a mini-G sheds light on the principles of G protein selectivity

scientific article published on 19 September 2018

Crystallization scale preparation of a stable GPCR signaling complex between constitutively active rhodopsin and G-protein

scientific article

Crystals of Native and Modified Bovine Rhodopsins and Their Heavy Atom Derivatives

Development and crystallization of a minimal thermostabilised G protein-coupled receptor.

scientific article

Development of an antibody fragment that stabilizes GPCR/G-protein complexes

scientific article published in Nature Communications

Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation

scientific article published on 19 March 2019

Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region

scientific article published on 15 August 2016

Electron Crystallographic Studies of Rhodopsin

Engineering G protein-coupled receptors to facilitate their structure determination.

scientific article published on 12 August 2009

Expression and purification of truncated, non-glycosylated turkey beta-adrenergic receptors for crystallization.

scientific article published on February 2003

Femtosecond X-ray diffraction from two-dimensional protein crystals.

scientific article

Femtosecond-to-millisecond structural changes in a light-driven sodium pump

scientific article published on 20 May 2020

GPCR Activation States Induced by Nanobodies and Mini-G Proteins Compared by NMR Spectroscopy

scientific article published on 17 December 2020

GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014.

scientific article published on 14 March 2015

Immobilization of arrestin-3 on different biosensor platforms for evaluating GPCR binding

scientific article published on 20 October 2020

Large scale expression and purification of the rat 5-HT2c receptor

scientific article published on 28 October 2014

Ligand channel in pharmacologically stabilized rhodopsin.

scientific article published on 19 March 2018

Ligands Stabilize Specific GPCR Conformations: But How?

Lipidic cubic phase injector is a viable crystal delivery system for time-resolved serial crystallography

scientific article

Lipidic cubic phase serial millisecond crystallography using synchrotron radiation

scientific article

Low resolution structure of bovine rhodopsin determined by electron cryo-microscopy.

scientific article published on May 1995

Membrane protein structural biology using X-ray free electron lasers

scientific article

Membranes

article

Molecular mechanism of phosphorylation-dependent arrestin activation

scientific article

Molecular signatures of G-protein-coupled receptors

scientific article

Orthorhombic crystal form of bacteriorhodopsin nucleated on benzamidine diffracting to 3.6 A resolution

scientific article published on 01 November 1993

Overproduction of membrane proteins

Perspective: Opportunities for ultrafast science at SwissFEL.

scientific article published in November 2017

Photocrosslinking between nucleic acids and proteins: general discussion

scientific article published on 04 April 2018

Preparation and analysis of two-dimensional crystals of rhodopsin

scientific article published on 01 January 2000

Preparation of an activated rhodopsin/transducin complex using a constitutively active mutant of rhodopsin ⬇️

scientific article published on November 2, 2011

Probing Gαi1 protein activation at single-amino acid resolution.

scientific article published on 10 August 2015

Production of GPCR and GPCR complexes for structure determination ⬇️

scientific article published on May 24, 2013

Projection Structure of an Invertebrate Rhodopsin

Projection structure of rhodopsin

scientific article published in Nature

Protein crystallography microdiffraction

scientific article

Recoverin Binds Exclusively to an Amphipathic Peptide at the N Terminus of Rhodopsin Kinase, Inhibiting Rhodopsin Phosphorylation without Affecting Catalytic Activity of the Kinase

scientific article published in Journal of Biological Chemistry

Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser

scientific article published on 14 June 2018

Retinal proteins — You can teach an old dog new tricks

Rhodopsin on tracks: new ways to go in signaling

scientific article published on April 2015

Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons

scientific article

Signal transduction: The rhodopsin story continued

scientific article published in Nature

Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II

scientific article

Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A

scientific article

Structural role of the T94I rhodopsin mutation in congenital stationary night blindness

scientific article

Structure of bovine rhodopsin in a trigonal crystal form.

scientific article

Structure of rhodopsin

article

Structure of rhodopsin and the metarhodopsin I photointermediate.

scientific article

Structure of the ligand-blocked periplasmic entrance of the bacterial multidrug efflux protein TolC.

scientific article

Structure of the µ-opioid receptor–Gi protein complex

scientific article published in Nature

Structure of β-Adrenergic Receptors

article

The 2.1 Å Resolution Structure of Cyanopindolol-Bound β1-Adrenoceptor Identifies an Intramembrane Na+ Ion that Stabilises the Ligand-Free Receptor

scientific article

The Three-dimensional Structure of Bovine Rhodopsin Determined by Electron Cryomicroscopy ⬇️

scientific article published on September 25, 2003

The Two-Photon Reversible Reaction of the Bistable Jumping Spider Rhodopsin-1

scientific article published on 05 March 2019

The counterion-retinylidene Schiff base interaction of an invertebrate rhodopsin rearranges upon light activation

scientific article published on 13 May 2019

The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

scientific article

The structural basis of agonist-induced activation in constitutively active rhodopsin ⬇️

scientific article published on March 9, 2011

Three-dimensional mass density mapping of cellular ultrastructure by ptychographic X-ray nanotomography

scientific article published on 12 October 2015

Three-dimensional structure of an invertebrate rhodopsin and basis for ordered alignment in the photoreceptor membrane.

scientific article published on November 2001

Time-resolved structural studies with serial crystallography: A new light on retinal proteins

scientific article published on 29 June 2015

Tracking G-protein-coupled receptor activation using genetically encoded infrared probes.

scientific article published on 11 April 2010

Two alternative conformations of a voltage-gated sodium channel

scientific article

Two distinct conformations of helix 6 observed in antagonist-bound structures of a  1-adrenergic receptor

scientific article

X-ray diffraction of heavy-atom labelled two-dimensional crystals of rhodopsin identifies the position of cysteine 140 in helix 3 and cysteine 316 in helix 8.

scientific article published on February 2002

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