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List of works by Robert O'Connor

A novel panel of protein biomarkers for predicting response to thalidomide-based therapy in newly diagnosed multiple myeloma patients

scientific article published on 25 February 2011

A phase I clinical and pharmacokinetic study of the multi-drug resistance protein-1 (MRP-1) inhibitor sulindac, in combination with epirubicin in patients with advanced cancer.

scientific article published on 27 April 2006

A review of mechanisms of circumvention and modulation of chemotherapeutic drug resistance.

scientific article published on May 2009

Artificial Neural Networks for Classification in Metabolomic Studies of Whole Cells Using 1H Nuclear Magnetic Resonance ⬇️

scientific article published on September 15, 2010

CYP1B1 expression is induced by docetaxel: effect on cell viability and drug resistance.

scientific article

Challenges of drug resistance in the management of pancreatic cancer ⬇️

scientific article published on October 1, 2010

Characterisation and manipulation of docetaxel resistant prostate cancer cell lines

scientific article

Determination of serum and tissue levels of phenazines including clofazimine

scientific article published on 01 June 1996

Development, validation and application of a sensitive LC-MS/MS method for the quantification of thalidomide in human serum, cells and cell culture medium.

scientific article

Drug metabolism-related genes as potential biomarkers: analysis of expression in normal and tumour breast tissue.

scientific article published on 27 September 2007

Drug resistance in cancer - searching for mechanisms, markers and therapeutic agents

scientific article published on December 2007

Enhanced in vitro invasiveness and drug resistance with altered gene expression patterns in a human lung carcinoma cell line after pulse selection with anticancer drugs.

scientific article published on September 2004

Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs)

article

Gene expression changes as markers of early lapatinib response in a panel of breast cancer cell lines

scientific article

Increased anti-tumour efficacy of doxorubicin when combined with sulindac in a xenograft model of an MRP-1-positive human lung cancer.

scientific article published on March 2004

Metabolomic studies of human lung carcinoma cell lines using in vitro (1)H NMR of whole cells and cellular extracts.

scientific article

Methods for generation of monoclonal antibodies to the very small drug hapten, 5-benzimidazolecarboxylic acid.

scientific article

Modulation of P-gp expression by lapatinib.

scientific article published on 6 July 2010

Overexpression of cytochrome P450 NADPH reductase sensitises MDA 231 breast carcinoma cells to 5-fluorouracil: possible mechanisms involved.

scientific article published on 7 December 2007

Rapid and sensitive liquid chromatography-tandem mass spectrometry for the quantitation of epirubicin and identification of metabolites in biological samples

scientific article

Recent developments in drug resistance and apoptosis research.

scientific article

Simultaneous determination of anthracyclines and taxanes in human serum using online sample extraction coupled to high performance liquid chromatography with UV detection.

scientific article published in June 2010

Simultaneous determination of efavirenz, rifampicin and its metabolite desacetyl rifampicin levels in human plasma.

scientific article published on 30 July 2011

Stable Aqueous Dispersions of Glycopeptide-Grafted Selectably Functionalized Magnetic Nanoparticles

scientific article published on 01 February 2013

Structure-activity relationship of indomethacin analogues for MRP-1, COX-1 and COX-2 inhibition. identification of novel chemotherapeutic drug resistance modulators.

scientific article

The pharmacology of cancer resistance.

scientific article published on May 2007

The pharmacology, metabolism, and chemistry of clofazimine.

scientific article published on January 1995

The use of LC-MS to identify differentially expressed proteins in docetaxel-resistant prostate cancer cell lines

scientific article published on July 2012

Tyrosine kinase inhibitors potentiate the cytotoxicity of MDR-substrate anticancer agents independent of growth factor receptor status in lung cancer cell lines.

scientific article

Use of proton NMR spectroscopy in the toxicological evaluation of new anti-mycobacterial agents

scientific article published on 01 May 1995

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