Search filters

List of works by Nicolas Coquelle

Activity, stability and structural studies of lactate dehydrogenases adapted to extreme thermal environments

scientific article

An ER-peroxisome tether exerts peroxisome population control in yeast

scientific article

An experimental point of view on hydration/solvation in halophilic proteins

scientific article

BRCA1 Circos: a visualisation resource for functional analysis of missense variants

scientific article

Chromophore twisting in the excited state of a photoswitchable fluorescent protein captured by time-resolved serial femtosecond crystallography

scientific article published on 11 September 2017

Comprehensive analysis of missense variations in the BRCT domain of BRCA1 by structural and functional assays.

scientific article

Development of an in-vivo active reversible butyrylcholinesterase inhibitor.

scientific article published on 21 December 2016

Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor

scientific article

FHA domain pThr binding specificity: it's all about me.

scientific article published on December 2010

Impact of BRCA1 BRCT Domain Missense Substitutions on Phosphopeptide Recognition ⬇️

scientific article published on May 10, 2011

N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer's agents

scientific article published on 19 November 2016

Neutron structures of <i>Leishmania mexicana</i> triosephosphate isomerase in complex with reaction-intermediate mimics shed light on the proton-shuttling steps

scientific article published on 03 June 2021

Observing the overall rocking motion of a protein in a crystal

scientific article

PARP pairs up to PARsylate

scientific article published on 05 July 2012

Perdeuteration, large crystal growth and neutron data collection of Leishmania mexicana triose-phosphate isomerase E65Q variant

scientific article published on 02 April 2019

Photoswitching mechanism of a fluorescent protein revealed by time-resolved crystallography and transient absorption spectroscopy

scientific article published on 06 February 2020

Raster-scanning serial protein crystallography using micro- and nano-focused synchrotron beams

scientific article

Sampling the conformational energy landscape of a hyperthermophilic protein by engineering key substitutions

scientific article

Serial Femtosecond Crystallography and Ultrafast Absorption Spectroscopy of the Photoswitchable Fluorescent Protein IrisFP

scientific article

Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade

scientific article published on 02 March 2020

Slow conformational exchange and overall rocking motion in ubiquitin protein crystals

scientific article

Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates ⬇️

scientific article published on December 14, 2011

Structure-based development of nitroxoline derivatives as potential multifunctional anti-Alzheimer agents

scientific article

The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity

scientific article published on 11 December 2017

The cytotoxic Staphylococcus aureus PSMα3 reveals a cross-α amyloid-like fibril

scientific article

Paulina is supported by:

About Paulina

Help