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List of works by Jean Cavarelli

A high resolution diffracting crystal form of the complex between yeast tRNAAsp and aspartyl-tRNA synthetase

scientific article published on 01 May 1988

Active site mapping of yeast aspartyl-tRNA synthetase by in vivo selection of enzyme mutations lethal for cell growth.

scientific article

Acyl derivatives of p-aminosulfonamides and dapsone as new inhibitors of the arginine methyltransferase hPRMT1.

scientific article published on 27 February 2011

Biochemical and NMR mapping of the interface between CREB-binding protein and ligand binding domains of nuclear receptor: beyond the LXXLL motif

scientific article published on 12 November 2004

Cloning, expression, purification and preliminary X-ray crystallographic analysis of mouse protein arginine methyltransferase 7.

scientific article published on 24 December 2013

Cloning, purification and crystallization of a Walker-type Pyrococcus abyssi ATPase family member.

scientific article published on 30 September 2005

Conformational flexibility of tRNA: structural changes in yeast tRNA(Asp) upon binding to aspartyl-tRNA synthetase.

scientific article

Crystal structure of the V-region of Streptococcus mutans antigen I/II at 2.4 A resolution suggests a sugar preformed binding site

scientific article

Crystal structure, biochemical and genetic characterization of yeast and E. cuniculi TAF(II)5 N-terminal domain: implications for TFIID assembly

scientific article

Crystallization and preliminary X-ray crystallographic analysis of yeast arginyl-tRNA synthetase-yeast tRNAArg complexes

scientific article published on 01 April 2000

Crystallization and preliminary X-ray crystallographic study of the wild type and two mutants of the CP1 hydrolytic domain from Aquifex aeolicus leucyl-tRNA synthetase.

scientific article published on 13 September 2005

Crystallogenesis studies on yeast aspartyl-tRNA synthetase: use of phase diagram to improve crystal quality

scientific article published on 01 January 1999

Electrostatic potential in aminoacylation by aspartyl-tRNAs synthetase.

scientific article published in January 1995

Evidence for assembly-dependent folding of protein and RNA in an icosahedral virus

scientific article

Expression, purification, and characterization of a new heterotetramer structure of leucyl-tRNA synthetase from Aquifex aeolicus in Escherichia coli.

scientific article

Expression, purification, crystallization and preliminary crystallographic study of isolated modules of the mouse coactivator-associated arginine methyltransferase 1.

scientific article published on 30 March 2007

Functional insights from high resolution structures of mouse protein arginine methyltransferase 6

scientific article

Functional insights from structures of coactivator-associated arginine methyltransferase 1 domains

scientific article

Hijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors

scientific article published on 01 June 2018

Identification of small-molecule enhancers of arginine methylation catalyzed by coactivator-associated arginine methyltransferase 1.

scientific article

Insight into the remarkable affinity and selectivity of the aminobenzosuberone scaffold for the M1 aminopeptidases family based on structure analysis.

scientific article published on 6 April 2017

L-Arginine recognition by yeast arginyl-tRNA synthetase

scientific article published on September 15, 1998

Molecular basis for the antiparasitic activity of a mercaptoacetamide derivative that inhibits histone deacetylase 8 (HDAC8) from the human pathogen schistosoma mansoni

scientific article

Mutation and evolution of the magnesium-binding site of a class II aminoacyl-tRNA synthetase.

scientific article published in June 2004

Noncanonical Tandem SH2 Enables Interaction of Elongation Factor Spt6 with RNA Polymerase II

scientific article

On the Structure and Function of the Phytoene Desaturase CRTI from Pantoea ananatis, a Membrane-Peripheral and FAD-Dependent Oxidase/Isomerase

scientific article

SECIS-binding protein 2 interacts with the SMN complex and the methylosome for selenoprotein mRNP assembly and translation

scientific article published on 23 January 2017

Structural basis for group A trichothiodystrophy

scientific article

Structural basis for hijacking of cellular LxxLL motifs by papillomavirus E6 oncoproteins

scientific article

Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoni

scientific article

Structural insight into arginine methylation by the mouse protein arginine methyltransferase 7: a zinc finger freezes the mimic of the dimeric state into a single active site

scientific article

Structural insights into transcription complexes.

scientific article published on 06 May 2011

Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors

scientific article published on 5 November 2016

Structure determination of the minimal complex between Tfb5 and Tfb2, two subunits of the yeast transcription/DNA-repair factor TFIIH: a retrospective study.

scientific article published on 19 June 2010

Structure of the Elongator cofactor complex Kti11/Kti13 provides insight into the role of Kti13 in Elongator-dependent tRNA modification

scientific article

Structures of RNA-binding proteins

scientific article published on August 1, 1997

TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL

scientific article

The 2.8 A structure of a T = 4 animal virus and its implications for membrane translocation of RNA.

scientific article

The class II aminoacyl-tRNA synthetases and their active site: evolutionary conservation of an ATP binding site

scientific article published on 01 May 1995

The free yeast aspartyl-tRNA synthetase differs from the tRNA(Asp)-complexed enzyme by structural changes in the catalytic site, hinge region, and anticodon-binding domain

scientific article published in June 2000

The structure of Staphylococcus aureus epidermolytic toxin A, an atypic serine protease, at 1.7 A resolution

scientific article

The structure of an Iws1/Spt6 complex reveals an interaction domain conserved in TFIIS, Elongin A and Med26

scientific article

Transition state mimics are valuable mechanistic probes for structural studies with the arginine methyltransferase CARM1.

scientific article published on 22 March 2017

Translationally controlled tumor protein is a target of tumor reversion

scientific article

Yeast aspartyl-tRNA synthetase: a structural view of the aminoacylation reaction

scientific article published on 01 January 1993

Yeast tRNA(Asp)-aspartyl-tRNA synthetase complex: low resolution crystal structure

scientific article published on 01 October 1987

Yeast tRNAAsp recognition by its cognate class II aminoacyl-tRNA synthetase

scientific article published in Nature

tRNA aminoacylation by arginyl-tRNA synthetase: induced conformations during substrates binding

scientific article