List of works - Jean-Marie Wurtz

A canonical structure for the ligand-binding domain of nuclear receptors

scientific article published on 01 January 1996

A mutation mimicking ligand-induced conformational change yields a constitutive RXR that senses allosteric effects in heterodimers ⬇️

scientific article published on September 15, 1997

A new class of transcription initiation factors, intermediate between TATA box-binding proteins (TBPs) and TBP-like factors (TLFs), is present in the marine unicellular organism, the dinoflagellate Crypthecodinium cohnii

scientific article

Antagonism in the human mineralocorticoid receptor.

scientific article

Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes

scientific article

Crucial role of the H11-H12 loop in stabilizing the active conformation of the human mineralocorticoid receptor

scientific article (publication date: August 2000)

Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a rec

scientific article published in April 2004

Cysteine mapping in conformationally distinct kinase nucleotide binding sites: application to the design of selective covalent inhibitors.

scientific article published on 15 February 2011

Defining and characterizing protein surface using alpha shapes.

scientific article published in July 2009

Functional insights from high resolution structures of mouse protein arginine methyltransferase 6

scientific article

Identification of an alternative ligand-binding pocket in the nuclear vitamin D receptor and its functional importance in 1alpha,25(OH)2-vitamin D3 signaling

scholarly article

Investigation of the binding interactions of progesterone using muteins of the human progesterone receptor ligand binding domain designed on the basis of a three-dimensional protein model

scientific article published on 01 January 1999

Molecular basis for the antiparasitic activity of a mercaptoacetamide derivative that inhibits histone deacetylase 8 (HDAC8) from the human pathogen schistosoma mansoni

scientific article

Partial defects in transcriptional activity of two novel DAX-1 mutations in childhood-onset adrenal hypoplasia congenita

article by Paul Laissue et al published November 2006 in Clinical Endocrinology

Reappraisal of the Role of Heat Shock Proteins as Regulators of Steroid Receptor Activity

scientific article published on 01 January 1998

Residues in the ligand binding domain that confer progestin or glucocorticoid specificity and modulate the receptor transactivation capacity.

scientific article published in July 2000

Sequences in the ligand-binding domains of the human androgen and progesterone receptors which determine their distinct ligand identities

scientific article published on 01 April 1997

Specific recognition of androgens by their nuclear receptor. A structure-function study

scientific article published on 01 August 2000

Structural insight into arginine methylation by the mouse protein arginine methyltransferase 7: a zinc finger freezes the mimic of the dimeric state into a single active site

scientific article

Structure-function analysis reveals the molecular determinants of the impaired biological function of DAX-1 mutants in AHC patients

scientific article published in May 2003

The TBP-like factor: an alternative transcription factor in metazoa?

scientific article

The bromodomain revisited.

scientific article published in May 1997

The monomeric orphan nuclear receptor Schistosoma mansoni Ftz-F1 dimerizes specifically and functionally with the schistosome RXR homologue, SmRXR1.

scientific article

Three-dimensional models of estrogen receptor ligand binding domain complexes, based on related crystal structures and mutational and structure-activity relationship data.

scientific article

Unfaithfulness and promiscuity of a mutant androgen receptor in a hormone-refractory prostate cancer.

scientific article published in February 2006

X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation.

scientific article

List of works by Jean-Marie Wurtz

A canonical structure for the ligand-binding domain of nuclear receptors

A mutation mimicking ligand-induced conformational change yields a constitutive RXR that senses allosteric effects in heterodimers ⬇️

A new class of transcription initiation factors, intermediate between TATA box-binding proteins (TBPs) and TBP-like factors (TLFs), is present in the marine unicellular organism, the dinoflagellate Crypthecodinium cohnii

Antagonism in the human mineralocorticoid receptor.

Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes

Crucial role of the H11-H12 loop in stabilizing the active conformation of the human mineralocorticoid receptor

Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a rec

Cysteine mapping in conformationally distinct kinase nucleotide binding sites: application to the design of selective covalent inhibitors.

Defining and characterizing protein surface using alpha shapes.

Functional insights from high resolution structures of mouse protein arginine methyltransferase 6

Identification of an alternative ligand-binding pocket in the nuclear vitamin D receptor and its functional importance in 1alpha,25(OH)2-vitamin D3 signaling

Investigation of the binding interactions of progesterone using muteins of the human progesterone receptor ligand binding domain designed on the basis of a three-dimensional protein model

Molecular basis for the antiparasitic activity of a mercaptoacetamide derivative that inhibits histone deacetylase 8 (HDAC8) from the human pathogen schistosoma mansoni

Partial defects in transcriptional activity of two novel DAX-1 mutations in childhood-onset adrenal hypoplasia congenita

Reappraisal of the Role of Heat Shock Proteins as Regulators of Steroid Receptor Activity

Residues in the ligand binding domain that confer progestin or glucocorticoid specificity and modulate the receptor transactivation capacity.

Sequences in the ligand-binding domains of the human androgen and progesterone receptors which determine their distinct ligand identities

Specific recognition of androgens by their nuclear receptor. A structure-function study

Structural insight into arginine methylation by the mouse protein arginine methyltransferase 7: a zinc finger freezes the mimic of the dimeric state into a single active site

Structure-function analysis reveals the molecular determinants of the impaired biological function of DAX-1 mutants in AHC patients

The TBP-like factor: an alternative transcription factor in metazoa?

The bromodomain revisited.

The monomeric orphan nuclear receptor Schistosoma mansoni Ftz-F1 dimerizes specifically and functionally with the schistosome RXR homologue, SmRXR1.

Three-dimensional models of estrogen receptor ligand binding domain complexes, based on related crystal structures and mutational and structure-activity relationship data.

Unfaithfulness and promiscuity of a mutant androgen receptor in a hormone-refractory prostate cancer.

X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation.