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List of works by Silvio Aime

1,2-hydroxypyridonate/terephthalamide complexes of gadolinium(III): synthesis, stability, relaxivity, and water exchange properties

scientific article

1,2-hydroxypyridonates as contrast agents for magnetic resonance imaging: TREN-1,2-HOPO.

scientific article

15N Magnetic Resonance Hyperpolarization via the Reaction of Parahydrogen with 15N-Propargylcholine ⬇️

scientific article published on June 26, 2012

1H and17O relaxometric investigations of the binding of Mn(II) ion to human serum albumin

A R2/R1 ratiometric procedure for a concentration-independent, pH-responsive, Gd(III)-based MRI agent

scientific article

A R2p /R1p ratiometric procedure to assess matrix metalloproteinase-2 activity by magnetic resonance imaging.

scientific article

A carborane-derivative "click" reaction under heterogeneous conditions for the synthesis of a promising lipophilic MRI/GdBNCT agent.

scientific article

A copper-activated magnetic resonance imaging contrast agent with improved turn-on relaxivity response and anion compatibility

scientific article

A general MRI-CEST ratiometric approach for pH imaging: demonstration of in vivo pH mapping with iobitridol

scientific article

A highly stable gadolinium complex with a fast, associative mechanism of water exchange.

scientific article

A multinuclear NMR relaxometry study of ternary adducts formed between heptadentate Gd(III) chelates and L-lactate

scientific article

A new ytterbium chelate as contrast agent in chemical shift imaging and temperature sensitive probe for MR spectroscopy

scientific article published on 01 May 1996

A novel 19F-NMR method for the investigation of the antioxidant capacity of biomolecules and biofluids

scientific article published on 01 August 1999

A novel method of cellular labeling: anchoring mr-imaging reporter particles on the outer cell surface.

scientific article

A novel non-facial mode of azulene cluster co-ordination. Crystal and molecular structure of the dicarbenoid Os3(μ-H)2(CO)9(μ3-η1∶η1∶η1-C10H6)

A paramagnetic MRI-CEST agent responsive to lactate concentration

scientific article

A paramagnetic probe to localize residues next to carboxylates on protein surfaces

scientific article published on 14 February 2002

A quantitative relaxometric version of the ELISA test for the measurement of cell surface biomarkers

scientific article

A relaxometric method for the assessment of intestinal permeability based on the oral administration of gadolinium-based MRI contrast agents

scientific article published on 11 February 2016

A theranostic approach based on the use of a dual boron/Gd agent to improve the efficacy of Boron Neutron Capture Therapy in the lung cancer treatment.

scientific article published on 14 January 2015

A vaccine targeting angiomotin induces an antibody response which alters tumor vessel permeability and hampers the growth of established tumors ⬇️

scientific article published on March 17, 2012

AAZTA: An Ideal Chelating Agent for the Development of 44 Sc PET Imaging Agents.

scientific article published on 18 January 2017

Advances in Metal-Based Probes for MR Molecular Imaging Applications ⬇️

scientific article published on January 1, 2010

Advances in bio-imaging: A survey from WWMR 2010 ⬇️

scientific article published on 03 March 2011

An MRI Method To Map Tumor Hypoxia Using Red Blood Cells Loaded with a pO2-Responsive Gd-Agent

scientific article published on 3 August 2015

An iron-based T1 contrast agent made of iron-phosphate complexes: in vitro and in vivo studies.

scientific article published on February 2007

Asparagine in plums detected by CEST-MRI.

scientific article

Assessment of iron absorption in mice by ICP-MS measurements of 57Fe levels

scientific article published on 19 October 2011

Azide, cyanide, fluoride, imidazole and pyridine binding to ferric and ferrous native horse heart cytochrome c and to its carboxymethylated derivative: a comparative study

scientific article published on 01 May 1996

B25716/1: a novel albumin-binding Gd-AAZTA MRI contrast agent with improved properties in tumor imaging

scientific article

Biodistribution of gadolinium-based contrast agents, including gadolinium deposition

scientific article

Blast from the past: the aluminum's ghost on the lanthanum salts.

scientific article

Block copolymer vesicles containing paramagnetic lanthanide complexes: a novel class of T1- and CEST MRI contrast agents

Boronated compounds for imaging guided BNCT applications.

scientific article published on June 2012

CEST and PARACEST Agents for Molecular Imaging

Carbon coated microshells containing nanosized Gd(iii) oxidic phases for multiple bio-medical applications

scientific article published on 08 October 2008

Cardio-chemical exchange saturation transfer magnetic resonance imaging reveals molecular signatures of endogenous fibrosis and exogenous contrast media.

scientific article

Catalytic effects of apoferritin interior surface residues on water proton exchange in lanthanide complexes.

scientific article

Challenges for molecular magnetic resonance imaging

scientific article published on May 2010

Chapter 10 - Lanthanide-loaded paramagnetic liposomes as switchable magnetically oriented nanovesicles

scientific article

Characterization of human hair melanin and its degradation products by means of magnetic resonance techniques

scientific article published on 01 May 2008

Chemical Shift and Relaxation Reagents in NMR*

Chemical exchange saturation transfer (CEST): an efficient tool for detecting molecular information on proteins' behaviour

scientific article published on 01 June 2014

Chemistry of molecular imaging.

scientific article

Cluster analysis of quantitative parametric maps from DCE-MRI: application in evaluating heterogeneity of tumor response to antiangiogenic treatment.

scientific article published on 31 March 2015

Combined delivery and magnetic resonance imaging of neural cell adhesion molecule-targeted doxorubicin-containing liposomes in experimentally induced Kaposi's sarcoma

scientific article published on 09 March 2010

Combined high resolution NMR and 1H and 17O relaxometric study sheds light on the solution structure and dynamics of the lanthanide(III) complexes of HPDO3A.

scientific article

Combined inhibition of PI3Kβ and PI3Kγ reduces fat mass by enhancing α-MSH-dependent sympathetic drive

scientific article published on 18 November 2014

Complete on/off responsive ParaCEST MRI contrast agents for copper and zinc

scientific article published on 01 August 2018

Contrast agents and mechanisms

scientific article published on 01 June 2011

Contrast agents for magnetic resonance angiographic applications: 1H and 17O NMR relaxometric investigations on two gadolinium(III) DTPA-like chelates endowed with high binding affinity to human serum albumin.

scientific article published in December 1999

Controlled mixing of lanthanide(III) ions in coacervate core micelles

scientific article

Copper-responsive magnetic resonance imaging contrast agents

scientific article

Correlation of Water Exchange Rate with Isomeric Composition in Diastereoisomeric Gadolinium Complexes of Tetra(carboxyethyl)dota and Related Macrocyclic Ligands

article

Curcumin/Gd loaded apoferritin: a novel "theranostic" agent to prevent hepatocellular damage in toxic induced acute hepatitis.

scientific article published on 16 April 2013

Current concepts on hyperpolarized molecules in MRI.

scientific article

Dendrimeric Gd(III) complex of a monophosphinated DOTA analogue: optimizing relaxivity by reducing internal motion.

scientific article published on 18 March 2005

Dependence of the relaxivity and luminescence of gadolinium and europium amino-acid complexes on hydrogencarbonate and pH

scholarly article by Silvio Aime et al published 1999 in Chemical Communications

Design and Synthesis of a γ(1)β(8)-Cyclodextrin Oligomer: A New Platform with Potential Application as a Dendrimeric Multicarrier

scientific article

Design and testing of paramagnetic liposome-based CEST agents for MRI visualization of payload release on pH-induced and ultrasound stimulation

scientific article published on 14 September 2013

Designing Novel Contrast Agents for Magnetic Resonance Imaging. Synthesis and Relaxometric Characterization of three Gadolinium(III) Complexes Based on Functionalized Pyridine-Containing Macrocyclic Ligands

Determination of ferric heme-human serum albumin by 1H NMR relaxometry.

scientific article

Determination of water permeability of paramagnetic liposomes of interest in MRI field

scientific article

Development and validation of a smoothing-splines-based correction method for improving the analysis of CEST-MR images.

scientific article

Differences in Molecular Structure Markedly Affect GBCA Elimination Behavior

scientific article published on 26 February 2019

Diolein Based Nanostructures as Targeted Theranostics.

scientific article published on May 2016

Dissociation kinetics of open-chain and macrocyclic gadolinium(III)-aminopolycarboxylate complexes related to magnetic resonance imaging: catalytic effect of endogenous ligands

scientific article published on 08 November 2012

Dual MRI-SPECT agent for pH-mapping

scientific article published on 19 November 2010

Dual-modality gene reporter for in vivo imaging

scientific article

EPR investigations of the iron domain in neuromelanin.

scientific article published in July 1997

Effect of a mesitylene-based ligand cap on the relaxometric properties of Gd(III) hydroxypyridonate MRI contrast agents.

scientific article published in September 2009

Effect of low and zero magnetic field on the hyperpolarization lifetime in parahydrogenated perdeuterated molecules.

scientific article

Effect of the intracellular localization of a Gd-based imaging probe on the relaxation enhancement of water protons

scientific article

Effects of Magnetic Field Cycle on the Polarization Transfer from Parahydrogen to Heteronuclei through Long-Range J-Couplings

scientific article published on 23 July 2015

Efficient cellular labeling by CD44 receptor-mediated uptake of cationic liposomes functionalized with hyaluronic acid and loaded with MRI contrast agents.

scientific article

Efficient relaxivity enhancement in dendritic gadolinium complexes: effective motional coupling in medium molecular weight conjugates

scientific article published on 17 December 2004

Encoding the frequency dependence in MRI contrast media: the emerging class of CEST agents

scientific article

Evaluation of 111In-labeled EPep and FibPep as tracers for fibrin SPECT imaging.

scientific article

Evaluation of the dose enhancement of combined10B +157Gd neutron capture therapy (NCT)

scientific article published on 05 August 2015

Evidence for in vivo macrophage mediated tumor uptake of paramagnetic/fluorescent liposomes.

scientific article published in December 2009

Evidence for the Role of Intracellular Water Lifetime as a Tumour Biomarker Obtained by In Vivo Field-Cycling Relaxometry

scientific article published on 14 April 2018

Extent of hydration of octadentate lanthanide complexes incorporating phosphinate donors: solution relaxometry and luminescence studies

Fe(III)-templated Gd(III) self-assemblies-a new route toward macromolecular MRI contrast agents

scientific article

First ex-vivo MRI co-localization of two LIPOCEST agents

scientific article

Frequency-encoded MRI-CEST agents based on paramagnetic liposomes/RBC aggregates.

scientific article

From spherical to osmotically shrunken paramagnetic liposomes: an improved generation of LIPOCEST MRI agents with highly shifted water protons

scientific article

Functional imaging of the angiogenic switch in a transgenic mouse model of human breast cancer by dynamic contrast enhanced magnetic resonance imaging.

scientific article published on 3 March 2016

Gadolinium(III) Complexes of dota-DerivedN-Sulfonylacetamides (H4(dota-NHSO2R)=10-{2-[(R)sulfonylamino]-2-oxoethyl}-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic Acid): A New Class of Relaxation Agents for Magnetic Resonance Imaging Applications

Gadolinium-binding cyclic hexapeptoids: synthesis and relaxometric properties.

scientific article published on 29 November 2013

Gadolinium-doped LipoCEST agents: a potential novel class of dual 1H-MRI probes

scientific article

Gd loading by hypotonic swelling: an efficient and safe route for cellular labeling

scientific article

Gd(DOTP)5-outer-sphere relaxation enhancement promoted by nitrogen bases.

scientific article published on November 1993

Gd(III)-BASED CONTRAST AGENTS FOR MRI

Gd-AAZTA-MADEC, an improved blood pool agent for DCE-MRI studies on mice on 1 T scanners.

scientific article

Gd-Loaded Liposomes asT1, Susceptibility, and CEST Agents, All in One

scientific article published on 09 February 2007

Gd-enhanced MR images of substrates other than water

scientific article

Gd-loaded-RBCs for the assessment of tumor vascular volume by contrast-enhanced-MRI.

scientific article

Glycoconjugates of gadolinium complexes for MRI applications

scientific article

HR-MAS of cells: A "cellular water shift" due to water-protein interactions?

scientific article

Hetero-tripodal hydroxypyridonate gadolinium complexes: syntheses, relaxometric properties, water exchange dynamics, and human serum albumin binding.

scientific article

High kinetic inertness of a bis-hydrated Gd-complex with a constrained AAZTA-like ligand.

scientific article

High relaxivity gadolinium hydroxypyridonate-viral capsid conjugates: nanosized MRI contrast agents.

scientific article

High relaxivity supramolecular adducts between human-liver fatty-acid-binding protein and amphiphilic Gd(III) complexes: structural basis for the design of intracellular targeting MRI probes

scientific article published on 4 July 2012

High-relaxivity gadolinium-modified high-density lipoproteins as magnetic resonance imaging contrast agents

scientific article

High-relaxivity magnetic resonance imaging (MRI) contrast agent based on supramolecular assembly between a gadolinium chelate, a modified dextran, and poly-beta-cyclodextrin.

scientific article published in January 2008

High-resolution NMR and relaxometric studies of Ln(III) complexes of relevance to MRI

Highly sensitive MRI chemical exchange saturation transfer agents using liposomes

scientific article published in August 2005

Highly shifted LIPOCEST agents based on the encapsulation of neutral polynuclear paramagnetic shift reagents

scientific article

Highly shifted proton MR imaging: cell tracking by using direct detection of paramagnetic compounds

scientific article

Highly soluble tris-hydroxypyridonate Gd(III) complexes with increased hydration number, fast water exchange, slow electronic relaxation, and high relaxivity

scientific article

How to design 13C para-hydrogen-induced polarization experiments for MRI applications

scientific article published on 03 December 2010

Hyperpolarized (13) C-labelled anhydrides as DNP precursors of metabolic MRI agents

scientific article published on 01 September 2012

Hyperpolarized (13)C-pyruvate magnetic resonance imaging in cancer diagnostics.

scientific article published on 09 May 2012

Image guided therapy: the advent of theranostic agents

scientific article published on 22 May 2012

Imaging probes—Introduction

scientific article published on 01 February 2011

Imaging the pH evolution of an acute kidney injury model by means of iopamidol, a MRI-CEST pH-responsive contrast agent

scientific article published on 11 October 2012

Improved paramagnetic liposomes for MRI visualization of pH triggered release

scientific article published on 20 May 2011

Improved route for the visualization of stem cells labeled with a Gd-/Eu-chelate as dual (MRI and fluorescence) agent

scientific article published on 01 May 2004

Improved syntheses of bis(beta-cyclodextrin) derivatives, new carriers for gadolinium complexes

scientific article published on 25 January 2006

In Vitro and In Vivo Assessment of Nonionic Iodinated Radiographic Molecules as Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Tumor Perfusion Agents

scientific article published on 12 October 2015

In Vivo Labeling of B16 Melanoma Tumor Xenograft with a Thiol-Reactive Gadolinium Based MRI Contrast Agent ⬇️

scientific article published on August 5, 2011

In Vivo MR Imaging of Fibrin in a Neuroblastoma Tumor Model by Means of a Targeting Gd-Containing Peptide

scientific article published on 15 April 2015

In vivo MRI multicontrast kinetic analysis of the uptake and intracellular trafficking of paramagnetically labeled liposomes

scientific article published on 15 March 2010

In vivo MRI visualization of different cell populations labeled with PARACEST agents.

scientific article

In vivo MRI visualization of release from liposomes triggered by local application of pulsed low-intensity non-focused ultrasound

scientific article published on 21 March 2014

In vivo maps of extracellular pH in murine melanoma by CEST-MRI.

scientific article published on 25 March 2013

Innovative magnetic resonance imaging diagnostic agents based on paramagnetic Gd(III) complexes

scientific article published on 01 January 2002

Insights into the use of paramagnetic Gd(III) complexes in MR-molecular imaging investigations.

scientific article

In Vivo Magnetic Resonance Imaging Detection of Paramagnetic Liposomes Loaded with Amphiphilic Gadolinium(III) Complexes: Impact of Molecular Structure on Relaxivity and Excretion Efficiency

scientific article published on 03 June 2013

Iopamidol: Exploring the potential use of a well-established x-ray contrast agent for MRI.

scientific article

Lack of Plasma Protein Hemopexin Results in Increased Duodenal Iron Uptake

scientific article

Lanthanide(III) complexes of tris(amide) PCTA derivatives as potential bimodal magnetic resonance and optical imaging agents

scientific article

Lanthanide-Loaded Paramagnetic Liposomes as Switchable Magnetically Oriented Nanovesicles

scientific article published on 22 March 2008

Lanthanide-loaded erythrocytes as highly sensitive chemical exchange saturation transfer MRI contrast agents.

scientific article

Ln(III)-DOTAMGly complexes: a versatile series to assess the determinants of the efficacy of paramagnetic chemical exchange saturation transfer agents for magnetic resonance imaging applications

scientific article published in April 2004

MEMRI and tumors: a method for the evaluation of the contribution of Mn(II) ions in the extracellular compartment.

scientific article published on 14 July 2015

MRI CEST at 1T with large µeff Ln(3+) complexes T m(3+)-HPDO3A: An efficient MRI pH reporter

scientific article

MRI Visualization of Melanoma Cells by Targeting Overexpressed Sialic Acid with a GdIII-dota-en-pba Imaging Reporter

scientific article published on 06 December 2012

MRI evaluation of the antitumor activity of paramagnetic liposomes loaded with prednisolone phosphate

scientific article

MRI nanoprobes based on chemical exchange saturation transfer: Ln(III) chelates anchored on the surface of mesoporous silica nanoparticles

scientific article published on 01 August 2014

MRI of cells and mice at 1 and 7 Tesla with Gd-targeting agents: when the low field is better!

scientific article

MRI tracking of macrophages labeled with glucan particles entrapping a water insoluble paramagnetic Gd-based agent

scientific article

MRI‐Guided Neutron Capture Therapy by Use of a Dual Gadolinium/Boron Agent Targeted at Tumour Cells through Upregulated Low‐Density Lipoprotein Transporters ⬇️

scientific article published on June 10, 2011

Macrocyclic paramagnetic agents for MRI: Determinants of relaxivity and strategies for their improvement

scientific article published on 28 October 2016

Magnetic Resonance Visualization of Tumor Angiogenesis by Targeting Neural Cell Adhesion Molecules with the Highly Sensitive Gadolinium-Loaded Apoferritin Probe

scientific article published on 01 September 2006

Magnetic resonance imaging detection of tumor cells by targeting low-density lipoprotein receptors with Gd-loaded low-density lipoprotein particles

scientific article

Magnetic resonance imaging of gadolinium-labeled pancreatic islets for experimental transplantation

scientific article published on 01 February 2007

Magnetic resonance imaging of the gastrointestinal tract: investigation of baby milk as a low cost contrast medium

scientific article published on September 1, 1992

Magnetic resonance imaging of tumor cells by targeting the amino acid transport system.

scientific article published on 18 May 2006

Magnetic resonance imaging visualization of targeted cells by the internalization of supramolecular adducts formed between avidin and biotinylated Gd3+ chelates.

scientific article

Mannich Reaction as a New Route to Pyridine-Based Polyaminocarboxylic Ligands

scientific article published on 01 April 2004

Maximizing the relaxivity of HSA-bound gadolinium complexes by simultaneous optimization of rotation and water exchange

scientific article published on 26 October 2007

Mesoporous silica nanoparticles functionalized with fluorescent and MRI reporters for the visualization of murine tumors overexpressing αvβ3 receptors

scientific article published on 10 March 2016

Metal containing nanosized systems for MR-Molecular Imaging applications

Methods for an improved detection of the MRI-CEST effect

scientific article

Mn-loaded apoferritin: a highly sensitive MRI imaging probe for the detection and characterization of hepatocarcinoma lesions in a transgenic mouse model

scientific article published on 01 May 2012

Modifying LnHPDO3A Chelates for Improved T1 and CEST MRI Applications

scientific article published on 20 February 2019

Modulation of the antioxidant activity of HO* scavengers by albumin binding: a 19F-NMR study.

scientific article published in August 2003

Modulation of the water exchange rates in [Gd–DO3A] complex by formation of ternary complexes with carboxylate ligands

Molecular recognition of sugars by lanthanide (III) complexes of a conjugate of N, N-bis[2-[bis[2-(1, 1-dimethylethoxy)-2-oxoethyl]amino]ethyl]glycine and phenylboronic acid

scientific article

NMR Studies of Melanins: Characterization of a Soluble Melanin Free Acid From Sepia Ink ⬇️

scientific article published on December 1, 1991

NMR investigation of the equilibrium partitioning of a water-soluble bile salt protein carrier to phospholipid vesicles

scientific article

NMR relaxometric investigation on human methemoglobin and fluoromethemoglobin. An improved quantitative in vitro assay of human methemoglobin.

scientific article published on June 1995

NMR relaxometric investigations of solid lipid nanoparticles (SLN) containing gadolinium(III) complexes.

scientific article

NMR structural studies of the supramolecular adducts between a liver cytosolic bile acid binding protein and gadolinium(III)-chelates bearing bile acids residues: molecular determinants of the binding of a hepatospecific magnetic resonance imaging c

scientific article published on 4 October 2007

NMR structure of two novel polyethylene glycol conjugates of the human growth hormone-releasing factor, hGRF(1-29)-NH2.

scientific article published in March 2003

NMR, Relaxometric, and Structural Studies of the Hydration and Exchange Dynamics of Cationic Lanthanide Complexes of Macrocyclic Tetraamide Ligands

scientific article published in 1999

Nanoparticle-based chemical exchange saturation transfer (CEST) agents

scientific article

Nature-inspired particles as carriers for multimodal molecular imaging applications

Neural-cell adhesion molecule (NCAM) expression by immature and tumor-derived endothelial cells favors cell organization into capillary-like structures

scientific article published on 9 January 2006

New cyclodextrin dimers and trimers capable of forming supramolecular adducts with shape-specific ligands

scientific article published on 20 November 2008

New hyperpolarized contrast agents for 13C-MRI from para-hydrogenation of oligooxyethylenic alkynes

scientific article

New insights for pursuing high relaxivity MRI agents from modelling the binding interaction of Gd(III) chelates to HSA

scientific article published on 01 May 2005

New paramagnetic supramolecular adducts for MRI applications based on non-covalent interactions between Gd(III)-complexes and beta- or gamma-cyclodextrin units anchored to chitosan.

scientific article

NorDATA: An original ligand based on the norbornane skeleton. Synthesis and thermodynamic characterization of metal complexes

Novel Contrast Agents for Magnetic Resonance Imaging. Synthesis and Characterization of the Ligand BOPTA and Its Ln(III) Complexes (Ln = Gd, La, Lu). X-ray Structure of Disodium (TPS-9-145337286-C-S)-[4-Carboxy-5,8,11-tris(carboxymethyl)-1-phenyl-2-o

article published in 1995

Novel paramagnetic macromolecular complexes derived from the linkage of a macrocyclic Gd(III) complex to polyamino acids through a squaric acid moiety.

scientific article

Nuclear magnetic relaxation dispersion profiles of substantia nigra pars compacta in Parkinson's disease patients are consistent with protein aggregation.

scientific article

Nuclear magnetic resonance studies of neutral lanthanide(III) complexes with tetraaza-macrocyclic ligands containing three phosphinate and one carboxamide co-ordinating arms

Nuclear magnetic resonance, luminescence and structural studies of lanthanide complexes with octadentate macrocyclic ligands bearing benzylphosphinate groups

On the fate of MRI Gd-based contrast agents in cells. Evidence for extensive degradation of linear complexes upon endosomal internalization.

scientific article published on 7 June 2013

On the role of the counter-ion in defining water structure and dynamics: order, structure and dynamics in hydrophilic and hydrophobic gadolinium salt complexes

scientific article

One-step synthesis of a new eight-membered cyclic ligand from glycine, formaldehyde and hypophosphorous acid

Optimized relaxivity and stability of [Gd(H(2,2)-1,2-HOPO)(H2O)]- for use as an MRI contrast agent.

scientific article

Optimizing the high-field relaxivity by self-assembling of macrocyclic Gd(III) complexes

scientific article

Osmotically shrunken LIPOCEST agents: an innovative class of magnetic resonance imaging contrast media based on chemical exchange saturation transfer.

scientific article

Oximation of acetyl(hydroxyimino)acetone: nuclear magnetic resonance spectroscopic, chemical, and X-ray crystallographic studies of the reaction products

Para-hydrogen induced polarization of Si-29 NMR resonances as a potentially useful tool for analytical applications

scientific article published on 24 June 2012

Para-hydrogenated glucose derivatives as potential 13C-hyperpolarized probes for magnetic resonance imaging.

scientific article published in May 2010

ParaHydrogen Induced Polarization of 13C carboxylate resonance in acetate and pyruvate

scientific article published on 05 January 2015

Paramagnetic CEST MRI Contrast Agents

Paramagnetic lanthanide(III) complexes as pH-sensitive chemical exchange saturation transfer (CEST) contrast agents for MRI applications

scientific article

Paramagnetic liposomes as innovative contrast agents for magnetic resonance (MR) molecular imaging applications

scientific article

Paramagnetic self-assembled nanoparticles as supramolecular MRI contrast agents

scientific article

Peptide Derivatized Lamellar Aggregates as Target-Specific MRI Contrast Agents

scientific article published on 01 May 2007

Picture of a chelate in exchange: the crystal structure of NaHoDOTMA, a 'semi'-hydrated chelate.

scientific article published on March 2013

Platinum(II)-gadolinium(III) complexes as potential single-molecular theranostic agents for cancer treatment

scientific article published on 26 September 2014

Polarization transfer from para-hydrogen to heteronuclei: effect of H/D substitution. The case of AA'X and A2A2'X spin systems

scientific article published on 18 October 2005

Poly-beta-cyclodextrin based platform for pH mapping via a ratiometric 19F/1H MRI method

scientific article published on 21 September 2009

Polymeric vesicles loaded with gadoteridol as reversible and concentration-independent magnetic resonance imaging thermometers

scientific article

Preparation and in vitro characterization of chitosan nanobubbles as theranostic agents.

scientific article published on 14 March 2015

Probing protein conformation in cells by EPR distance measurements using Gd3+ spin labeling.

scientific article

Properties, Solution State Behavior, and Crystal Structures of Chelates of DOTMA ⬇️

scientific article published on August 5, 2011

Proteomics as a tool to improve investigation of substantial equivalence in genetically modified organisms: the case of a virus-resistant tomato.

scientific article

Prototropic and Water-Exchange Processes in Aqueous Solutions of Gd(III) Chelates

PrototropicvsWhole Water Exchange Contributions to the Solvent Relaxation Enhancement in the Aqueous Solution of a Cationic Gd3+Macrocyclic Complex

scientific article published in 1997

Pushing the sensitivity envelope of lanthanide-based magnetic resonance imaging (MRI) contrast agents for molecular imaging applications

scientific article

Quantification of the expression level of integrin receptor alpha(v)beta3 in cell lines and MR imaging with antibody-coated iron oxide particles.

scientific article published on October 2006

Quantitative description of radiofrequency (RF) power-based ratiometric chemical exchange saturation transfer (CEST) pH imaging

scientific article published on 23 March 2015

Re-evaluation of the water exchange lifetime value across red blood cell membrane.

scientific article published on 29 December 2015

Reduction/dissolution of a beta-MnOOH nanophase in the ferritin cavity to yield a highly sensitive, biologically compatible magnetic resonance imaging agent

scientific article published on 01 January 2010

Relaxometric and luminescence behaviour of triaquahexaazamacrocyclic complexes, the gadolinium complex displaying a high relaxivity with a pronounced pH dependence

Relaxometric and modelling studies of the binding of a lipophilic Gd-AAZTA complex to fatted and defatted human serum albumin

scientific article published on 01 January 2007

Relaxometric and solution NMR structural studies on ditopic lanthanide(III) complexes of a phosphinate analogue of DOTA with a fast rate of water exchange.

scientific article

Relaxometric characterization of human hemalbumin.

scientific article

Relaxometric evaluation of novel manganese(II) complexes for application as contrast agents in magnetic resonance imaging

scientific article

Relaxometric investigations and MRI evaluation of a liposome-loaded pH-responsive gadolinium(III) complex

scientific article published on 20 June 2012

Relaxometric studies for food characterization: the case of balsamic and traditional balsamic vinegars

scientific article

Release of a Paramagnetic Magnetic Resonance Imaging Agent from Liposomes Triggered by Low Intensity Non-Focused Ultrasound

Release of toxic Gd3+ ions to tumour cells by vitamin B12 bioconjugates.

scientific article published in August 2009

Role of the reaction intermediates in determining PHIP (parahydrogen induced polarization) effect in the hydrogenation of acetylene dicarboxylic acid with the complex [Rh (dppb)]+ (dppb: 1,4-bis(diphenylphosphino)butane)

scientific article published on 01 March 2014

SPECT imaging of fibrin using fibrin-binding peptides

scientific article published in May 2013

Sensitive MRI detection of internalized T1 contrast agents using magnetization transfer contrast.

scientific article published on 16 October 2015

Separation of intra- and extracellular lactate NMR signals using a lanthanide shift reagent

scientific article published in January 2002

Simultaneous MR imaging for tissue engineering in a rat model of stroke

scientific article

Slow clearance gadolinium-based extracellular and intravascular contrast media for three-dimensional MR angiography.

scientific article

Society Spotlight: European Commission-supported Development of Targeted Nanomedicines: did MediTrans Make a difference? ⬇️

scientific article published on July 1, 2011

Solid-state 31P CP/MAS NMR vs. solution study of bis(tertiary phosphines)

scientific article published on 01 October 1993

Solution Structures, Stabilities, Kinetics, and Dynamics of DO3A and DO3A–Sulphonamide Complexes

article

Solution and Solid-State Characterization of Highly Rigid, Eight-Coordinate Lanthanide(III) Complexes of a Macrocyclic Tetrabenzylphosphinate

article published in 1994

Solution structure of the supramolecular adduct between a liver cytosolic bile acid binding protein and a bile acid-based gadolinium(III)-chelate, a potential hepatospecific magnetic resonance imaging contrast agent

scientific article

Sonosensitive theranostic liposomes for preclinical in vivo MRI-guided visualization of doxorubicin release stimulated by pulsed low intensity non-focused ultrasound

scientific article

Stabilization of the T-state of ferrous human adult and fetal hemoglobin by Ln(III) complexes: a thermodynamic study

scientific article published on 01 August 1998

Structural determinants of fluoride and formate binding to hemoglobin and myoglobin: crystallographic and 1H-NMR relaxometric study.

scientific article published on January 1996

Structural variations across the lanthanide series of macrocyclic DOTA complexes: insights into the design of contrast agents for magnetic resonance imaging.

scientific article

Structural, luminescence, and NMR studies of the reversible binding of acetate, lactate, citrate, and selected amino acids to chiral diaqua ytterbium, gadolinium, and europium complexes

scientific article

Structure and relaxivity of macrocyclic gadolinium complexes incorporating pyridyl and 4-morpholinopyridyl substituents

Structure-Function Relationships of Iodinated Contrast Media and Risk of Nephrotoxicity ⬇️

scientific article published on January 1, 2012

Substituent effects on Gd(III)-based MRI contrast agents: optimizing the stability and selectivity of the complex and the number of coordinated water molecules.

scientific article

Successful entrapping of liposomes in glucan particles: an innovative micron-sized carrier to deliver water-soluble molecules

scientific article published on 4 September 2014

Supramolecular Adducts between Poly‐L‐arginine and [TmIIIdotp]: A Route to Sensitivity‐Enhanced Magnetic Resonance Imaging–Chemical Exchange Saturation Transfer Agents ⬇️

scientific article published on September 29, 2003

Supramolecular Adducts of Negatively Charged Lanthanide(III) DOTP Chelates and Cyclodextrins Functionalized with Ammonium Groups: Mass Spectrometry and Nuclear Magnetic Resonance Studies

article

Supramolecular protamine/Gd-loaded liposomes adducts as relaxometric protease responsive probes

scientific article

Synthesis and Characterization of Triosmium Clusters Containing the Bidentate Ligand Ph2PCH2CH2SMe: Detection of an Isomerization Reaction Involving Bridging and Chelating Ligand Coordination Modes

Synthesis and characterization of a Gd(III) based contrast agent responsive to thiol containing compounds.

scientific article

Synthesis and characterization of an MRI Gd-based probe designed to target the translocator protein.

scientific article

Synthesis and physicochemical characterization of carbon backbone modified [Gd(TTDA)(H2O)]2- derivatives

scientific article

Synthesis and relaxometric characterization of a MRI Gd-based probe responsive to glutamic acid decarboxylase enzymatic activity.

scientific article published on 15 March 2013

Synthesis and solution thermodynamic study of rigidified and functionalised EGTA derivatives

scientific article published on 30 April 2008

Synthesis and testing of a p‐H2 hyperpolarized 13C probe based on the pyrazolo[1,5‐a]pyrimidineacetamide DPA‐713, an MRI vector to target the peripheral benzodiazepine receptors ⬇️

scientific article published on November 17, 2011

Synthesis of Gd(III)-C-palmitamidomethyl-C'-DOTAMA-C(6)-o-carborane: a new dual agent for innovative MRI/BNCT applications.

scientific article

Synthesis of a carborane-containing cholesterol derivative and evaluation as a potential dual agent for MRI/BNCT applications.

scientific article published on April 2014

Synthesis of new polyoxapolycarboxylic ligands for lanthanide(III) ions complexation

Synthesis of the Gd(III) complex with a tetrazole-armed macrocyclic ligand as a potential MRI contrast agent

Synthesis, NMR, relaxometry and circularly polarised luminescence studies of macrocyclic monoamidetris(phosphinate) complexes bearing a remote chiral centre

Target visualization by MRI using the avidin/biotin amplification route: synthesis and testing of a biotin-Gd-DOTA monoamide trimer

scientific article published in July 2010

Targeting exofacial protein thiols with Gd(III) complexes. An efficient procedure for MRI cell labelling.

scientific article published on 26 January 2009

Targeting ferritin receptors for the selective delivery of imaging and therapeutic agents to breast cancer cells.

scientific article

Targeting of human renal tumor-derived endothelial cells with peptides obtained by phage display

scientific article

Ternary complexes between cationic GdIII chelates and anionic metabolites in aqueous solution: an NMR relaxometric study

scientific article

The Role of Equilibrium and Kinetic Properties in the Dissociation of Gd[DTPA-bis(methylamide)] (Omniscan) at near to Physiological Conditions

scientific article published on 12 February 2015

The Role of the Amino Protecting Group during Parahydrogenation of Protected Dehydroamino Acids

scientific article published on 05 November 2015

The Selectivity of Reversible Oxy-Anion Binding in Aqueous Solution at a Chiral Europium and Terbium Center: Signaling of Carbonate Chelation by Changes in the Form and Circular Polarization of Luminescence Emission

scholarly article by James I. Bruce et al published October 2000 in Journal of the American Chemical Society

The effect of ligand scaffold size on the stability of tripodal hydroxypyridonate gadolinium complexes.

scientific article published in April 2003

The effects of intramolecular H-bond formation on the stability constant and water exchange rate of the Gd(III)-diethylenetriamine-N'-(3-amino-1,1-propylenephosphonic)-N, N,N'',N''-tetraacetate complex

scientific article published on 01 March 2007

The hydroboration reaction as a key for a straightforward synthesis of new MRI-NCT agents

The release of Doxorubicin from liposomes monitored by MRI and triggered by a combination of US stimuli led to a complete tumor regression in a breast cancer mouse model.

scientific article published on 2 April 2016

The structure of the sugar residue in glycated human serum albumin and its molecular recognition by phenylboronate

scientific article published in May 2003

The use of contrast agents with fast field-cycling magnetic resonance imaging.

scientific article published on 30 November 2010

Theranostic nanomedicine.

scientific article published on 05 May 2011

Thermodynamic analysis of hydration in human serum heme-albumin

scientific article

Towards a successful clinical implementation of fluorescence-guided surgery

scientific article

Towards improved boron neutron capture therapy agents: evaluation of in vitro cellular uptake of a glutamine-functionalized carborane.

scientific article published on 10 April 2009

Towards targeted MRI: new MRI contrast agents for sialic acid detection

scientific article

Tunable imaging of cells labeled with MRI-PARACEST agents.

scientific article published on March 2005

Tuning the coordination number of hydroxypyridonate-based gadolinium complexes: implications for MRI contrast agents.

scientific article

Use of labile precursors for the generation of hyperpolarized molecules from hydrogenation with parahydrogen and aqueous-phase extraction.

scientific article

Variation of water exchange dynamics with ligand structure and stereochemistry in lanthanide complexes based on 1,4-diazepine derivatives

scientific article

Water exchange across the erythrocyte plasma membrane studied by HR-MAS NMR spectroscopy.

scientific article

Well-defined, multifunctional nanostructures of a paramagnetic lipid and a lipopeptide for macrophage imaging.

scientific article

YbIII-HPDO3A: A Dual pH- and Temperature-Responsive CEST Agent

scientific article published on 18 January 2011

Yeast cell wall particles: a promising class of nature-inspired microcarriers for multimodal imaging

scientific article published on 01 September 2011

[Gd-AAZTA]-: A New Structural Entry for an Improved Generation of MRI Contrast Agents

scientific article published on 01 November 2004

[GdPCP2A(H(2)O)(2)](-): a paramagnetic contrast agent designed for improved applications in magnetic resonance imaging.

scientific article

[Yb(AAZTA)(H2O)]-: an unconventional ParaCEST MRI probe

scientific article published on 7 February 2018

para-Hydrogenation of unsaturated moieties on poly(lysine) derived substrates for the development of novel hyperpolarized MRI contrast agents

scientific article published on 23 September 2005

α-trideuteromethyl[15N]glutamine: A long-lived hyperpolarized perfusion marker.

scientific article

β-Gal gene expression MRI reporter in melanoma tumor cells. Design, synthesis, and in vitro and in vivo testing of a Gd(III) containing probe forming a high relaxivity, melanin-like structure upon β-Gal enzymatic activation.

scientific article

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