List of works by Ziying Yan

A Preclinical Study in Rhesus Macaques for Cystic Fibrosis to Assess Gene Transfer and Transduction by AAV1 and AAV5 with a Dual-Luciferase Reporter System.

scientific article published on 20 July 2017

A novel chimeric adenoassociated virus 2/human bocavirus 1 parvovirus vector efficiently transduces human airway epithelia.

scientific article published on 30 July 2013

A novel liver-directed gene delivery system using an autonomously replicating vector specifically expressed in AFP positive hepatoma cells.

scientific article published in February 1998

AAV serotypes have distinctive interactions with domains of the cellular receptor AAVR.

scientific article published on 5 July 2017

Adeno-associated virus-targeted disruption of the CFTR gene in cloned ferrets.

scientific article

Analysis of adeno-associated virus progenitor cell transduction in mouse lung.

scientific article

Analysis of cis and trans Requirements for DNA Replication at the Right-End Hairpin of the Human Bocavirus 1 Genome.

scientific article published on 22 June 2016

Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size.

scientific article published on 11 April 2018

Biological Differences in rAAV Transduction of Airway Epithelia in Humans and in Old World Non-human Primates.

scientific article

Comparative biology of rAAV transduction in ferret, pig and human airway epithelia.

scientific article published on 30 August 2007

Comparative processing and function of human and ferret cystic fibrosis transmembrane conductance regulator.

scientific article

Control of hepatic nuclear superoxide production by glucose 6-phosphate dehydrogenase and NADPH oxidase-4

scientific article

DNA Damage Signaling Is Required for Replication of Human Bocavirus 1 DNA in Dividing HEK293 Cells

scientific article

Definitive localization of intracellular proteins: Novel approach using CRISPR-Cas9 genome editing, with glucose 6-phosphate dehydrogenase as a model

scientific article

Detargeting Lentiviral-Mediated CFTR Expression in Airway Basal Cells Using miR-106b

scientific article published on 06 October 2020

Development of a Novel Recombinant Adeno-Associated Virus Production System Using Human Bocavirus 1 Helper Genes

Directing integrin-linked endocytosis of recombinant AAV enhances productive FAK-dependent transduction.

scientific article published on 10 January 2012

Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis.

scientific article

Dual reporter comparative indexing of rAAV pseudotyped vectors in chimpanzee airway.

scientific article published on 13 October 2009

Dual therapeutic utility of proteasome modulating agents for pharmaco-gene therapy of the cystic fibrosis airway.

scientific article published in December 2004

Efficiency of chimeraplast gene targeting by direct nuclear injection using a GFP recovery assay.

scientific article published in February 2003

Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus.

scientific article

Enhancement of muscle gene delivery with pseudotyped adeno-associated virus type 5 correlates with myoblast differentiation.

scientific article published on August 2001

Establishment of a Recombinant AAV2/HBoV1 Vector Production System in Insect Cells

scientific article published on 17 April 2020

Ferret and pig models of cystic fibrosis: prospects and promise for gene therapy

scientific article

Gastrointestinal pathology in juvenile and adult CFTR-knockout ferrets.

scientific article published on 15 March 2014

Glandular Proteome Identifies Antiprotease Cystatin C as a Critical Modulator of Airway Hydration and Clearance.

scientific article published on 3 September 2015

Hepatocytes produce TNF-α following hypoxia-reoxygenation and liver ischemia-reperfusion in a NADPH oxidase- and c-Src-dependent manner

scientific article published on 02 May 2013

Highly Efficient Transgenesis in Ferrets Using CRISPR/Cas9-Mediated Homology-Independent Insertion at the ROSA26 Locus

scientific article published in Scientific Reports

Human Bocavirus 1 Is a Novel Helper for Adeno-Associated Virus Replication.

scientific article published on 28 June 2017

Human Bocavirus Type-1 Capsid Facilitates the Transduction of Ferret Airways by Adeno-Associated Virus Genomes

scientific article published on 10 May 2017

Human Parvovirus Infection of Human Airway Epithelia Induces Pyroptotic Cell Death via Inhibiting Apoptosis.

scientific article published on 11 October 2017

Hybrid adeno-associated virus bearing nonhomologous inverted terminal repeats enhances dual-vector reconstruction of minigenes in vivo.

scientific article

Identification and Functional Analysis of Novel Nonstructural Proteins of Human Bocavirus 1.

scientific article

In utero and postnatal VX-770 administration rescues multiorgan disease in a ferret model of cystic fibrosis

scientific article published on 01 March 2019

In vitro modeling of human bocavirus 1 infection of polarized primary human airway epithelia.

scientific article published on 23 January 2013

Indexing TNF-alpha gene expression using a gene-targeted reporter cell line

scientific article

Intracellular trafficking of adeno-associated viral vectors.

scientific article

Inverted terminal repeat sequences are important for intermolecular recombination and circularization of adeno-associated virus genomes

scientific article

Lung phenotype of juvenile and adult cystic fibrosis transmembrane conductance regulator-knockout ferrets.

scientific article

Molecular characterization of suppression of hepatitis B virus transcription by hepatitis C virus core protein.

scientific article published in December 1997

Nonstructural Protein NP1 of Human Bocavirus 1 Plays a Critical Role in the Expression of Viral Capsid Proteins

scientific article published on 24 February 2016

Optimization of Recombinant Adeno-Associated Virus-Mediated Expression for Large Transgenes, Using a Synthetic Promoter and Tandem Array Enhancers

scientific article published on 20 April 2015

Parvovirus Expresses a Small Noncoding RNA That Plays an Essential Role in Virus Replication

scientific article published on 25 January 2017

Polarity influences the efficiency of recombinant adenoassociated virus infection in differentiated airway epithelia.

scientific article

Postentry processing of recombinant adeno-associated virus type 1 and transduction of the ferret lung are altered by a factor in airway secretions.

scientific article published on September 2013

Production of CFTR-null and CFTR-DeltaF508 heterozygous pigs by adeno-associated virus-mediated gene targeting and somatic cell nuclear transfer

scientific article

Progress and prospects: techniques for site-directed mutagenesis in animal models.

scientific article

Recombinant AAV-mediated gene delivery using dual vector heterodimerization.

scientific article published on January 2002

Replication of an Autonomous Human Parvovirus in Non-dividing Human Airway Epithelium Is Facilitated through the DNA Damage and Repair Pathways

scientific article published on 14 January 2016

Scavengase p20: a novel family of bacterial antioxidant enzymes.

scientific article published in April 1997

Structural analysis of adeno-associated virus transduction circular intermediates.

scientific article published in August 1999

Ubiquitination of both adeno-associated virus type 2 and 5 capsid proteins affects the transduction efficiency of recombinant vectors.

scientific article published on March 2002

Unique biologic properties of recombinant AAV1 transduction in polarized human airway epithelia.

scientific article

Unique characteristics of AAV1, 2, and 5 viral entry, intracellular trafficking, and nuclear import define transduction efficiency in HeLa cells.

scientific article published on 28 June 2011

Virus-mediated transduction of murine retina with adeno-associated virus: effects of viral capsid and genome size.

scientific article

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