List of works - Xuemin Xu

Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family.

scientific article

Angiotensin II-induced protein kinase D activation is regulated by protein kinase Cdelta and mediated via the angiotensin II type 1 receptor in vascular smooth muscle cells.

scientific article

Both the N-terminal fragment and the protein-protein interaction domain (PDZ domain) are required for the pro-apoptotic activity of presenilin-associated protein PSAP

scientific article

Effects of gamma-secretase cleavage-region mutations on APP processing and Abeta formation: interpretation with sequential cleavage and alpha-helical model

scientific article

Gamma-secretase catalyzes sequential cleavages of the AbetaPP transmembrane domain.

scientific article published on January 2009

Histamine induces Egr-1 expression in human aortic endothelial cells via the H1 receptor-mediated protein kinase Cdelta-dependent ERK activation pathway.

scientific article published on 5 August 2008

Histamine induces activation of protein kinase D that mediates tissue factor expression and activity in human aortic smooth muscle cells.

scientific article

Identification of a new presenilin-dependent zeta-cleavage site within the transmembrane domain of amyloid precursor protein.

scientific article published on 13 October 2004

Identification of a novel PSD-95/Dlg/ZO-1 (PDZ)-like protein interacting with the C terminus of presenilin-1

scientific article

Lysophosphatidic Acid Triggers Apoptosis in HeLa Cells through the Upregulation of Tumor Necrosis Factor Receptor Superfamily Member 21.

scientific article published on 19 February 2017

Lysophosphatidic acid induces early growth response gene 1 expression in vascular smooth muscle cells: CRE and SRE mediate the transcription.

scientific article published on 23 February 2006

Lysophosphatidic acid induces increased BACE1 expression and Aβ formation.

scientific article

Lysophosphatidic acid induction of tissue factor expression in aortic smooth muscle cells.

scientific article published in February 2003

Matricellular protein Cyr61 bridges lysophosphatidic acid and integrin pathways leading to cell migration.

scientific article published on 26 December 2013

PSAP induces a unique Apaf-1 and Smac-dependent mitochondrial apoptotic pathway independent of Bcl-2 family proteins

scientific article

Pen-2 is dispensable for endoproteolysis of presenilin 1, and nicastrin-Aph subcomplex is important for both γ-secretase assembly and substrate recruitment

scientific article

Regulation of brain G-protein go by Alzheimer's disease gene presenilin-1.

scientific article published in June 1998

The GxxxG motif in the transmembrane domain of AbetaPP plays an essential role in the interaction of CTF beta with the gamma-secretase complex and the formation of amyloid-beta

scientific article

The matricellular protein Cyr61 is a key mediator of platelet-derived growth factor-induced cell migration

scientific article

The same gamma-secretase accounts for the multiple intramembrane cleavages of APP

scientific article

Thrombin rapidly induces protein kinase D phosphorylation, and protein kinase C delta mediates the activation.

scientific article published on 12 November 2002

List of works by Xuemin Xu

Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family.

Angiotensin II-induced protein kinase D activation is regulated by protein kinase Cdelta and mediated via the angiotensin II type 1 receptor in vascular smooth muscle cells.

Both the N-terminal fragment and the protein-protein interaction domain (PDZ domain) are required for the pro-apoptotic activity of presenilin-associated protein PSAP

Effects of gamma-secretase cleavage-region mutations on APP processing and Abeta formation: interpretation with sequential cleavage and alpha-helical model

Gamma-secretase catalyzes sequential cleavages of the AbetaPP transmembrane domain.

Histamine induces Egr-1 expression in human aortic endothelial cells via the H1 receptor-mediated protein kinase Cdelta-dependent ERK activation pathway.

Histamine induces activation of protein kinase D that mediates tissue factor expression and activity in human aortic smooth muscle cells.

Identification of a new presenilin-dependent zeta-cleavage site within the transmembrane domain of amyloid precursor protein.

Identification of a novel PSD-95/Dlg/ZO-1 (PDZ)-like protein interacting with the C terminus of presenilin-1

Lysophosphatidic Acid Triggers Apoptosis in HeLa Cells through the Upregulation of Tumor Necrosis Factor Receptor Superfamily Member 21.

Lysophosphatidic acid induces early growth response gene 1 expression in vascular smooth muscle cells: CRE and SRE mediate the transcription.

Lysophosphatidic acid induces increased BACE1 expression and Aβ formation.

Lysophosphatidic acid induction of tissue factor expression in aortic smooth muscle cells.

Matricellular protein Cyr61 bridges lysophosphatidic acid and integrin pathways leading to cell migration.

PSAP induces a unique Apaf-1 and Smac-dependent mitochondrial apoptotic pathway independent of Bcl-2 family proteins

Pen-2 is dispensable for endoproteolysis of presenilin 1, and nicastrin-Aph subcomplex is important for both γ-secretase assembly and substrate recruitment

Regulation of brain G-protein go by Alzheimer's disease gene presenilin-1.

The GxxxG motif in the transmembrane domain of AbetaPP plays an essential role in the interaction of CTF beta with the gamma-secretase complex and the formation of amyloid-beta

The matricellular protein Cyr61 is a key mediator of platelet-derived growth factor-induced cell migration

The same gamma-secretase accounts for the multiple intramembrane cleavages of APP

Thrombin rapidly induces protein kinase D phosphorylation, and protein kinase C delta mediates the activation.