List of works - Vyacheslav Filichev

1-, 2-, and 4-ethynylpyrenes in the structure of twisted intercalating nucleic acids: structure, thermal stability, and fluorescence relationship

scientific article published in January 2008

Application of Cu(I)-catalyzed azide-alkyne cycloaddition for the design and synthesis of sequence specific probes targeting double-stranded DNA.

scientific article

Assembly Dependent Fluorescence Enhancing Nucleic Acids in Sequence-Specific Detection of Double-Stranded DNA

scientific article published on 02 December 2013

Assembly Dependent Fluorescence Enhancing Nucleic Acids in Sequence-Specific Detection of Double-Stranded DNA

scientific article published on 04 December 2013

Cationic modified nucleic acids for use in DNA hairpins and parallel triplexes

scientific article published on 27 April 2011

DNA G-quadruplexes show strong interaction with DNA methyltransferases in vitro.

scientific article

DNA glue: 1-, 2- and 4-ethynylpyrenes in the structure of twisted intercalating nucleic acids (TINAs), DNA duplexes/triplexes and interstrand excimer formation

scientific article

DNA visualization in single molecule studies carried out with optical tweezers: Covalent versus non-covalent attachment of fluorophores.

scientific article published on 8 September 2015

DNA-Based Assemblies for Photochemical Upconversion

scientific article published on 12 October 2015

Differential Inhibition of APOBEC3 DNA-Mutator Isozymes by Fluoro- and Non-Fluoro-Substituted 2'-Deoxyzebularine Embedded in Single-Stranded DNA

scientific article published on 19 December 2019

Easily denaturing nucleic acids derived from intercalating nucleic acids: thermal stability studies, dual duplex invasion and inhibition of transcription start

scientific article

Effects of Pressure and pH on the Physical Stability of an I-Motif DNA Structure

scientific article published on 04 June 2019

Enhanced Inhibition of Transcription Start by Targeting with 2′-OMe Pentaribonucleotides Comprising Locked Nucleic Acids and Intercalating Nucleic Acids

scientific article published on 01 July 2005

Enhanced anti-HIV-1 activity of G-quadruplexes comprising locked nucleic acids and intercalating nucleic acids

scientific article

G-Quadruplex Supramolecular Assemblies in Photochemical Upconversion.

scientific article published on 12 May 2016

G-quadruplex structures and CpG methylation cause drop-out of the maternal allele in polymerase chain reaction amplification of the imprinted MEST gene promoter

scientific article

Helicases, G4-DNAs, and drug design

scientific article published on 13 May 2014

Heterochromatin protein 1α interacts with parallel RNA and DNA G-quadruplexes

scientific article published on 01 January 2020

Hexofuranosyl thymidines inserted into oligodeoxynucleotides via their two exocyclic hydroxy groups. Oligo synthesis and RNase H activity

scientific article

High Thermal Stability of 5′-5′-Linked Alternate Hoogsteen Triplexes at Physiological pH

scientific article published on 01 August 2006

Identification of a new G-quadruplex motif in the KRAS promoter and design of pyrene-modified G4-decoys with antiproliferative activity in pancreatic cancer cells

scientific article

Inhibiting APOBEC3 Activity with Single-Stranded DNA Containing 2'-Deoxyzebularine Analogues

scientific article published on 28 November 2018

Intercalating Nucleic Acids: The Influence of Linker Length and Intercalator Type on Their Duplex Stabilities

scientific article published on 01 January 2004

Intercalating nucleic acids (INAs) with insertion of N-(pyren-1-ylmethyl)-(3R,4R)-4-(hydroxymethyl)pyrrolidin-3-ol. DNA (RNA) duplex and DNA three-way junction stabilities

scientific article published in January 2003

Intercalating nucleic acids: The inversion of the stereocenter in 1-O-(pyren-1-ylmethyl)glycerol from R to S. Thermal stability towards ssDNA, ssRNA and its own type of oligodeoxynucleotides

Interdependence of pyrene interactions and tetramolecular G4-DNA assembly

scientific article published on 01 March 2015

Locked nucleic acids and intercalating nucleic acids in the design of easily denaturing nucleic acids: thermal stability studies

scientific article published in December 2004

Molecular engineering of guanine-rich sequences: Z-DNA, DNA triplexes, and G-quadruplexes.

scientific article published on 07 February 2013

NMR-based method of small changes reveals how DNA mutator APOBEC3A interacts with its single-stranded DNA substrate

scientific article published on 22 March 2017

Neutral and Negatively Charged Phosphate Modifications Altering Thermal Stability, Kinetics of Formation and Monovalent Ion Dependence of DNA G-Quadruplexes

scientific article published on 24 January 2019

Optimization of the sequence of twisted intercalating nucleic acids (TINA) forming triple helix with the polypurine tract of the proviral HIV DNA.

scientific article

Purine twisted-intercalating nucleic acids: a new class of anti-gene molecules resistant to potassium-induced aggregation

scientific article published on 2 May 2008

Selective inhibition of APOBEC3 enzymes by single-stranded DNAs containing 2'-deoxyzebularine

scientific article published on 01 November 2019

Significantly enhanced DNA thermal stability resulting from porphyrin H-aggregate formation in the minor groove of the duplex

scientific article published on 01 September 2010

Silencing of BCR/ABL Chimeric Gene in Human Chronic Myelogenous Leukemia Cell Line K562 by siRNA-Nuclear Export Signal Peptide Conjugates.

scientific article

Stabilization of Parallel Triplexes by Twisted Intercalating Nucleic Acids (TINAs) Incorporating 1,2,3-Triazole Units and Prepared by Microwave-Accelerated Click Chemistry

scientific article published on 01 January 2007

Stable and selective formation of hoogsteen-type triplexes and duplexes using twisted intercalating nucleic acids (TINA) prepared via postsynthetic Sonogashira solid-phase coupling reactions

scientific article

Synthesis and incorporation of an alpha-hexofuranosyl thymidine into oligodeoxynucleotides via its two exocyclic OH-groups

scientific article published on February 2004

Synthesis of 1′-aza-C-nucleosides from (3R,4R)-4-(hydroxymethyl)pyrrolidin-3-ol

article published in 2001

Synthesis of an aza analogue of 2-deoxy-D-ribofuranose and its homologues.

scientific article published in July 2001

Synthesis of twisted intercalating nucleic acids possessing acridine derivatives. Thermal stability studies

scientific article

Synthesis of β-pyrrolic-modified porphyrins and their incorporation into DNA

scientific article published on 18 April 2011

The effect of INA [(R)-1-O-(1-pyrenylmethyl)glycerol] insertions on the structure and biological activity of a G-quadruplex from a critical KRAS G-rich sequence.

scientific article published on January 2007

The importance of phosphates for DNA G-quadruplex formation: evaluation of zwitterionic G-rich oligodeoxynucleotides

scientific article published on 12 April 2020

Towards metal-mediated g-quartet analogues: 1,2,4-triazole nucleotides.

scientific article published on January 2015

Triplex formation by pyrene-labelled probes for nucleic acid detection in fluorescence assays

scientific article

Triplex glue by synthesizing conjugated flexible intercalators

scientific article

Triplex‐Forming Twisted Intercalating Nucleic Acids (TINAs): Design Rules, Stabilization of Antiparallel DNA Triplexes and Inhibition of G‐Quartet‐Dependent Self‐Association ⬇️

scientific article published on October 17, 2011

α-2'-Deoxyguanosine can switch DNA G-quadruplex topologies from antiparallel to parallel

scientific article published on 01 April 2019

List of works by Vyacheslav Filichev

1-, 2-, and 4-ethynylpyrenes in the structure of twisted intercalating nucleic acids: structure, thermal stability, and fluorescence relationship

Application of Cu(I)-catalyzed azide-alkyne cycloaddition for the design and synthesis of sequence specific probes targeting double-stranded DNA.

Assembly Dependent Fluorescence Enhancing Nucleic Acids in Sequence-Specific Detection of Double-Stranded DNA

Assembly Dependent Fluorescence Enhancing Nucleic Acids in Sequence-Specific Detection of Double-Stranded DNA

Cationic modified nucleic acids for use in DNA hairpins and parallel triplexes

DNA G-quadruplexes show strong interaction with DNA methyltransferases in vitro.

DNA glue: 1-, 2- and 4-ethynylpyrenes in the structure of twisted intercalating nucleic acids (TINAs), DNA duplexes/triplexes and interstrand excimer formation

DNA visualization in single molecule studies carried out with optical tweezers: Covalent versus non-covalent attachment of fluorophores.

DNA-Based Assemblies for Photochemical Upconversion

Differential Inhibition of APOBEC3 DNA-Mutator Isozymes by Fluoro- and Non-Fluoro-Substituted 2'-Deoxyzebularine Embedded in Single-Stranded DNA

Easily denaturing nucleic acids derived from intercalating nucleic acids: thermal stability studies, dual duplex invasion and inhibition of transcription start

Effects of Pressure and pH on the Physical Stability of an I-Motif DNA Structure

Enhanced Inhibition of Transcription Start by Targeting with 2′-OMe Pentaribonucleotides Comprising Locked Nucleic Acids and Intercalating Nucleic Acids

Enhanced anti-HIV-1 activity of G-quadruplexes comprising locked nucleic acids and intercalating nucleic acids

G-Quadruplex Supramolecular Assemblies in Photochemical Upconversion.

G-quadruplex structures and CpG methylation cause drop-out of the maternal allele in polymerase chain reaction amplification of the imprinted MEST gene promoter

Helicases, G4-DNAs, and drug design

Heterochromatin protein 1α interacts with parallel RNA and DNA G-quadruplexes

Hexofuranosyl thymidines inserted into oligodeoxynucleotides via their two exocyclic hydroxy groups. Oligo synthesis and RNase H activity

High Thermal Stability of 5′-5′-Linked Alternate Hoogsteen Triplexes at Physiological pH

Identification of a new G-quadruplex motif in the KRAS promoter and design of pyrene-modified G4-decoys with antiproliferative activity in pancreatic cancer cells

Inhibiting APOBEC3 Activity with Single-Stranded DNA Containing 2'-Deoxyzebularine Analogues

Intercalating Nucleic Acids: The Influence of Linker Length and Intercalator Type on Their Duplex Stabilities

Intercalating nucleic acids (INAs) with insertion of N-(pyren-1-ylmethyl)-(3R,4R)-4-(hydroxymethyl)pyrrolidin-3-ol. DNA (RNA) duplex and DNA three-way junction stabilities

Intercalating nucleic acids: The inversion of the stereocenter in 1-O-(pyren-1-ylmethyl)glycerol from R to S. Thermal stability towards ssDNA, ssRNA and its own type of oligodeoxynucleotides

Interdependence of pyrene interactions and tetramolecular G4-DNA assembly

Locked nucleic acids and intercalating nucleic acids in the design of easily denaturing nucleic acids: thermal stability studies

Molecular engineering of guanine-rich sequences: Z-DNA, DNA triplexes, and G-quadruplexes.

NMR-based method of small changes reveals how DNA mutator APOBEC3A interacts with its single-stranded DNA substrate

Neutral and Negatively Charged Phosphate Modifications Altering Thermal Stability, Kinetics of Formation and Monovalent Ion Dependence of DNA G-Quadruplexes

Optimization of the sequence of twisted intercalating nucleic acids (TINA) forming triple helix with the polypurine tract of the proviral HIV DNA.

Purine twisted-intercalating nucleic acids: a new class of anti-gene molecules resistant to potassium-induced aggregation

Selective inhibition of APOBEC3 enzymes by single-stranded DNAs containing 2'-deoxyzebularine

Significantly enhanced DNA thermal stability resulting from porphyrin H-aggregate formation in the minor groove of the duplex

Silencing of BCR/ABL Chimeric Gene in Human Chronic Myelogenous Leukemia Cell Line K562 by siRNA-Nuclear Export Signal Peptide Conjugates.

Stabilization of Parallel Triplexes by Twisted Intercalating Nucleic Acids (TINAs) Incorporating 1,2,3-Triazole Units and Prepared by Microwave-Accelerated Click Chemistry

Stable and selective formation of hoogsteen-type triplexes and duplexes using twisted intercalating nucleic acids (TINA) prepared via postsynthetic Sonogashira solid-phase coupling reactions

Synthesis and incorporation of an alpha-hexofuranosyl thymidine into oligodeoxynucleotides via its two exocyclic OH-groups

Synthesis of 1′-aza-C-nucleosides from (3R,4R)-4-(hydroxymethyl)pyrrolidin-3-ol

Synthesis of an aza analogue of 2-deoxy-D-ribofuranose and its homologues.

Synthesis of twisted intercalating nucleic acids possessing acridine derivatives. Thermal stability studies

Synthesis of β-pyrrolic-modified porphyrins and their incorporation into DNA

The effect of INA [(R)-1-O-(1-pyrenylmethyl)glycerol] insertions on the structure and biological activity of a G-quadruplex from a critical KRAS G-rich sequence.

The importance of phosphates for DNA G-quadruplex formation: evaluation of zwitterionic G-rich oligodeoxynucleotides

Towards metal-mediated g-quartet analogues: 1,2,4-triazole nucleotides.

Triplex formation by pyrene-labelled probes for nucleic acid detection in fluorescence assays

Triplex glue by synthesizing conjugated flexible intercalators

Triplex‐Forming Twisted Intercalating Nucleic Acids (TINAs): Design Rules, Stabilization of Antiparallel DNA Triplexes and Inhibition of G‐Quartet‐Dependent Self‐Association ⬇️

α-2'-Deoxyguanosine can switch DNA G-quadruplex topologies from antiparallel to parallel