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List of works by Patrick Auberger

(13)C/(12)C isotope ratios of organic acids, glucose and fructose determined by HPLC-co-IRMS for lemon juices authenticity

scientific article published on 11 September 2013

A Jurkat T cell variant resistant to death receptor-induced apoptosis. Correlation with heat shock protein (Hsp) 27 and 70 levels.

scientific article

A New Hydroxylated Nonaprenylhydroquinone from the Mediterranean Marine Sponge Sarcotragus spinosulus ⬇️

scientific article published on July 7, 2011

A chymotryptic-type protease inhibitor decreases interleukin 2 synthesis and induces prostaglandin production in Jurkat T cells

scientific article published on 01 January 1989

A chymotryptic-type serine protease is required for IL-2 production by Jurkat T cells.

scientific article published on August 1990

A new posttranslational regulation of REDD1/DDIT4 through cleavage by caspase 3 modifies its cellular function

scientific article published on 24 July 2014

A survey of the signaling pathways involved in megakaryocytic differentiation of the human K562 leukemia cell line by molecular and c-DNA array analysis.

scientific article published on February 2006

AMPK- and p62/SQSTM1-dependent autophagy mediate resveratrol-induced cell death in chronic myelogenous leukemia.

scientific article

ATP-competitive Plk1 inhibitors induce caspase 3-mediated Plk1 cleavage and activation in hematopoietic cell lines.

scientific article published on 23 December 2017

Acadesine Circumvents Azacitidine Resistance in Myelodysplastic Syndrome and Acute Myeloid Leukemia

scientific article published on 25 December 2019

Acadesine kills chronic myelogenous leukemia (CML) cells through PKC-dependent induction of autophagic cell death

scientific article

Active stromelysin-3 (MMP-11) increases MCF-7 survival in three-dimensional Matrigel culture via activation of p42/p44 MAP-kinase

scientific article (publication date: September 2003)

All tyrosine kinase inhibitor-resistant chronic myelogenous cells are highly sensitive to Ponatinib ⬇️

scientific article published on December 1, 2012

Altered T cell surface glycosylation in HIV-1 infection results in increased susceptibility to galectin-1-induced cell death.

scientific article published on 18 August 2003

An absolute requirement for Fyn in T cell receptor-induced caspase activation and apoptosis

scientific article published on 01 August 2001

An miRNA-DNMT1 Axis Is Involved in Azacitidine Resistance and Predicts Survival in Higher-Risk Myelodysplastic Syndrome and Low Blast Count Acute Myeloid Leukemia

scientific article

Anti-inflammatory activity of Mitraphylline isolated from Uncaria tomentosa bark

scientific article

Apoptosis and autophagy have opposite roles on imatinib-induced K562 leukemia cell senescence.

scientific article published on 16 August 2012

Apoptosis and erythroid differentiation triggered by Bcr-Abl inhibitors in CML cell lines are fully distinguishable processes that exhibit different sensitivity to caspase inhibition.

scientific article published on 9 October 2006

Autophagy is required for CSF-1-induced macrophagic differentiation and acquisition of phagocytic functions.

scientific article

Autophagy, a key mechanism of oncogenesis and resistance in leukemia

scientific article published on 12 December 2016

Azacitidine resistance caused by LAMP2 deficiency: a therapeutic window for the use of autophagy inhibitors in MDS/AML patients?

scientific article published on 01 March 2019

Azacitidine-resistant SKM1 myeloid cells are defective for AZA-induced mitochondrial apoptosis and autophagy.

scientific article published on 15 July 2011

BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic mice

scientific article published on 25 July 2016

BCL2L10 positive cells in bone marrow are an independent prognostic factor of azacitidine outcome in myelodysplastic syndrome and acute myeloid leukemia

scientific article published on 27 April 2017

BCR-ABL/p62/SQSTM1: a cannibal embrace.

scientific article

Blocking NF-kappaB activation in Jurkat leukemic T cells converts the survival agent and tumor promoter PMA into an apoptotic effector.

scientific article published in May 2002

CD10 (Endopeptidase 24.11) Is a Thymic Peptide-Degrading Enzyme Possibly Involved in the Regulation of Thymocyte Functions

scientific article published on 01 January 1997

CD10 inhibitors increase f-Met-Leu-Phe-induced neutrophil transmigration ⬇️

scientific article published on March 1, 1998

CD10 is expressed on human thymic epithelial cell lines and modulates thymopentin-induced cell proliferation.

scientific article published on October 1997

CD10 plays a specific role in early thymic development

article

Caspase 1/11 Deficiency or Pharmacological Inhibition Mitigates Psoriasis-Like Phenotype in Mice

scientific article published on 17 December 2018

Caspase inhibition protects from liver injury following ischemia and reperfusion in rats

scientific article published on 01 January 2000

Caspase-3-derived C-terminal product of synphilin-1 displays antiapoptotic function via modulation of the p53-dependent cell death pathway.

scientific article published on 22 February 2006

Chaperone-Mediated Autophagy and Its Emerging Role in Hematological Malignancies

scientific article published on 16 October 2019

Characterization and purification of T lymphocyte aminopeptidase B: a putative marker of T cell activation

scientific article

Characterization and purification of a guanidinobenzoatase: a possible marker of human renal carcinoma

scientific article published on 01 July 1992

Chymotryptic-type protease inhibitors block the increase in Ca2+ and Il-2 production in activated Jurkat T cells

scientific article published on 01 February 1989

Cleavage and relocation of the tyrosine kinase P59FYN during Fas-mediated apoptosis in T lymphocytes

scientific article published on 01 July 1999

Cleavage of Fyn and Lyn in their N-terminal unique regions during induction of apoptosis: a new mechanism for Src kinase regulation.

scientific article

Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis.

scientific article

Cleavage of the Serum Response Factor during Death Receptor-induced Apoptosis Results in an Inhibition of the c-FOSPromoter Transcriptional Activity

scientific article published in Journal of Biological Chemistry

Comparative analysis of proteins labelled with [35S]methionine in the liver in vivo and in freshly isolated and short-term-cultured hepatocytes in vitro

scientific article published on 01 September 1982

Cooperation of amphiregulin and insulin-like growth factor-1 inhibits Bax- and Bad-mediated apoptosis via a protein kinase C-dependent pathway in non-small cell lung cancer cells.

scientific article

DNA Damage and the Activation of the p53 Pathway Mediate Alterations in Metabolic and Secretory Functions of Adipocytes

scientific article published on 7 July 2016

Differential SP220K expression in renal carcinoma and oncocytoma cells

scientific article published on 01 September 1997

Differential requirements for ERK1/2 and P38 MAPK activation by thrombin in T cells. Role of P59Fyn and PKCepsilon.

scientific article published in April 2001

Differentiation inducing factor 3 mediates its anti-leukemic effect through ROS-dependent DRP1-mediated mitochondrial fission and induction of caspase-independent cell death

scientific article published on 24 March 2016

Distinct mechanisms regulate 5-HT2 and thrombin receptor desensitization.

scientific article published on March 1995

Downregulation of caspases and Fas ligand expression, and increased lifespan of neutrophils after transmigration across intestinal epithelium.

scientific article published in February 2003

Dual role of Sp3 transcription factor as an inducer of apoptosis and a marker of tumour aggressiveness

scientific article

Effect of Caspase Inhibition on Thymic Apoptosis in Hemorrhagic Shock

scientific article published on 01 March 2007

Effects of growth factors on hormonal stimulation of amino acid transport in primary cultures of rat hepatocytes.

scientific article published on February 1983

Effects of polyamines on cyclic AMP-mediated stimulation of amino acid transport in isolated rat hepatocytes.

scientific article published on November 1983

Endopeptidase 24.11 (CD10/NEP) is required for phorbol ester-induced growth arrest in Jurkat T cells

scientific article published on 01 September 1997

Escherichia coli α-hemolysin counteracts the anti-virulence innate immune response triggered by the Rho GTPase activating toxin CNF1 during bacteremia

scientific article

Evidence for a p23 caspase-cleaved form of p27[KIP1] involved in G1 growth arrest.

scientific article published on June 1999

Fas ligand expression following normothermic liver ischemia-reperfusion

scientific article published on 01 May 2005

FeCl3-promoted and ultrasound-assisted synthesis of resveratrol O-derived glycoside analogs.

scientific article

Gab2 signaling in chronic myeloid leukemia cells confers resistance to multiple Bcr-Abl inhibitors.

scientific article

Gene expression profiling of human liver transplants identifies an early transcriptional signature associated with initial poor graft function.

scientific article

Gene expression profiling of imatinib and PD166326-resistant CML cell lines identifies Fyn as a gene associated with resistance to BCR-ABL inhibitors.

scientific article published on 30 June 2009

Gene expression profiling of normal human pulmonary fibroblasts following coculture with non-small-cell lung cancer cells reveals alterations related to matrix degradation, angiogenesis, cell growth and survival

article

Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation.

scientific article published on 7 December 2009

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Helicobacter pylori Lipopolysaccharide Hinders Polymorphonuclear Leucocyte Apoptosis

scientific article published on 01 March 2001

High levels of functional endopeptidase 24.11 (CD10) activity on human thymocytes: preferential expression on immature subsets

scientific article published on 01 July 1994

How recent advances in high-risk myelodysplastic syndrome physiopathology may impact future treatments.

scientific article published on January 2013

Human polymorphonuclear leukocytes are sensitive in vitro to Helicobacter pylori vaca toxin

scientific article published in December 2006

Hypomethylating agents reactivate FOXO3A in acute myeloid leukemia

scientific article published on 15 July 2011

IL-34 and CSF-1 display an equivalent macrophage differentiation ability but a different polarization potential.

scientific article published on 10 January 2018

Imatinib induces mitochondria-dependent apoptosis of the Bcr-Abl-positive K562 cell line and its differentiation toward the erythroid lineage.

scientific article published on November 2003

Imatinib mesylate (STI571) decreases the vascular endothelial growth factor plasma concentration in patients with chronic myeloid leukemia.

scientific article published on 19 February 2004

Imatinib triggers mesenchymal-like conversion of CML cells associated with increased aggressiveness.

scientific article

Implication and Regulation of AMPK during Physiological and Pathological Myeloid Differentiation

scientific article published on 30 September 2018

In Vitro and in Vivo Evaluation of Fully Substituted (5-(3-Ethoxy-3-oxopropynyl)-4-(ethoxycarbonyl)-1,2,3-triazolyl-glycosides as Original Nucleoside Analogues to Circumvent Resistance in Myeloid Malignancies

scientific article published on 17 January 2017

Induction of different types of cell death after normothermic liver ischemia-reperfusion

scientific article published on 01 December 2010

Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia.

scientific article published on 06 September 2013

Inhibition of apoptosis induced by heat shock preconditioning is associated with decreased phagocytosis in human polymorphonuclear leukocytes through inhibition of Rac and Cdc42

Inhibition of hormonal induction of tyrosine aminotransferase by polyamines in freshly isolated rat hepatocytes.

scientific article published on September 1983

Inhibition of imatinib-mediated apoptosis by the caspase-cleaved form of the tyrosine kinase Lyn in chronic myelogenous leukemia cells.

scientific article published on 2 April 2009

Inhibition of the NF-kappaB survival pathway via caspase-dependent cleavage of the IKK complex scaffold protein and NF-kappaB essential modulator NEMO.

scientific article published on 12 October 2007

Inhibitors of chymotrypsin-like activities selectively block the mitotic pathway in rat hepatoma cells.

scientific article published in January 1990

Injection of Staphylococcus aureus EDIN by the Bacillus anthracis protective antigen machinery induces vascular permeability

scientific article

Insulin enhances protein phosphorylation in isolated hepatocytes by inhibiting an amiloride sensitive phosphatase

scientific article published on 01 June 1982

Insulin regulation of protein phosphorylation in hepatocytes. Studies using two effectors: amiloride and natural aliphatic polyamines.

scientific article

Involvement of mast cells in gastritis caused by Helicobacter pylori: a potential role in epithelial cell apoptosis

scientific article

Isoform-specific contribution of protein kinase C to prion processing.

scientific article

Isolation and characterization of a T lymphocyte mutant defective in the protein kinase C signal transduction pathway.

scientific article published on September 1991

Jurkat T cells express a functional neutral endopeptidase activity (CALLA) involved in T cell activation ⬇️

scientific article published on November 1, 1992

LAMP2 expression dictates azacytidine response and prognosis in MDS/AML

scientific article published on 03 January 2019

Leukemic cell xenograft in zebrafish embryo for investigating drug efficacy.

scientific article

Low-dose vemurafenib induces complete remission in a case of hairy-cell leukemia with a V600E mutation.

scientific article published on 8 January 2013

Mechanism of action of the multikinase inhibitor Foretinib.

scientific article published in December 2011

Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells ⬇️

scientific article published on November 1, 2011

Metformin inhibits melanoma development through autophagy and apoptosis mechanisms.

scientific article

Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1.

scientific article published on 3 May 2011

Modular synthesis of new C-aryl-nucleosides and their anti-CML activity

scientific article published on 24 March 2018

Monomeric 55-kDa guanidinobenzoatase switches to a serine proteinase activity upon tetramerization. Tetrameric proteinase SP 220 K appears as the native form

scientific article published on 01 May 1994

Monosomal karyotype improves IPSS‐R stratification in MDS and AML patients treated with Azacitidine ⬇️

scientific article published on July 23, 2013

Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp ⬇️

scientific article published on June 27, 2013

Nephroblastoma overexpressed/cysteine-rich protein 61/connective tissue growth factor/nephroblastoma overexpressed gene-3 (NOV/CCN3), a selective adrenocortical cell proapoptotic factor, is down-regulated in childhood adrenocortical tumors

scientific article

Neprilysin, a novel target for ultraviolet B regulation of melanogenesis via melanocortins

scientific article published on 01 September 2000

Persistent activation of the Fyn/ERK kinase signaling axis mediates imatinib resistance in chronic myelogenous leukemia cells through upregulation of intracellular SPARC.

scientific article published on 23 November 2010

Phenotypic and genotypic characterization of azacitidine-sensitive and resistant SKM1 myeloid cell lines

scientific article

Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.

scientific article published on October 2003

Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia

scientific article

Ponatinib circumvents all types of imatinib resistance in chronic myelogenous leukemia cell lines.

scientific article published on 10 May 2013

Pro-inflammatory proteins S100A9 and tumor necrosis factor-α suppress erythropoietin elaboration in myelodysplastic syndromes

scientific article published on 5 October 2017

Proper macrophagic differentiation requires both autophagy and caspase activation.

scientific article published on July 2012

Protein kinase activation by warm and cold hypoxia- reoxygenation in primary-cultured rat hepatocytes-JNK(1)/SAPK(1) involvement in apoptosis

scientific article published on 01 November 2000

Proteolytic regulation of Forkhead transcription factor FOXO3a by caspase-3-like proteases

scientific article (publication date: 17 July 2003)

RSK2 is a new Pim2 target with pro-survival functions in FLT3-ITD-positive acute myeloid leukemia.

scientific article

Rat liver injury after normothermic ischemia is prevented by a phosphinic matrix metalloproteinase inhibitor

scientific article published on 14 November 2001

Regulation of protein phosphorylation by polyamines in hepatocytes.

scientific article published on October 1984

Regulation of thymic development by neprilysin inhibition

scientific article published on 01 January 1997

RelB reduces thymocyte apoptosis and regulates terminal thymocyte maturation ⬇️

scientific article published on January 1, 2002

Resistance to sunitinib in renal clear cell carcinoma results from sequestration in lysosomes and inhibition of the autophagic flux

scientific article published on 27 August 2015

Retinoic acid regulates Fas-induced apoptosis in Jurkat T cells: reversal of mitogen-mediated repression of Fas DISC assembly.

scientific article

Rho GTPase is activated by cytotoxic necrotizing factor 1 in peripheral blood T lymphocytes: potential cytotoxicity for intestinal epithelial cells

scientific article published on March 2003

SP220K is a novel matrix serine proteinase ⬇️

scientific article published on July 17, 1998

Secretion of a major phosphorylated glycoprotein by hepatocytes. Characterization of specific antibodies and investigations of the processing, excretion kinetics, and phosphorylation

article published in 1985

Sestrin2 integrates Akt and mTOR signaling to protect cells against energetic stress-induced death

scientific article published on 14 December 2012

Severe thymic atrophy in a mouse model of skin inflammation accounts for impaired TNFR1 signaling

scientific article

Siva-1 and an alternative splice form lacking the death domain, Siva-2, similarly induce apoptosis in T lymphocytes via a caspase-dependent mitochondrial pathway

scientific article

Stimulation of the T-cell antigen receptor-CD3 complex signaling pathway by the tyrosine phosphatase inhibitor pervanadate is mediated by inhibition of CD45: evidence for two interconnected Lck/Fyn- or zap-70-dependent signaling pathways.

scientific article

Structure elucidation of the new citharoxazole from the Mediterranean deep-sea sponge Latrunculia (Biannulata) citharistae

scientific article published on 14 July 2011

Study of a growth hormone-regulated protein secreted by rat hepatocytes: cDNA cloning, anti-protease activity and regulation of its synthesis by various hormones.

scientific article

Successful re-treatment of a relapsed V600E mutated HCL patient with low-dose vemurafenib.

scientific article

Synthesis and anti-cancer activities of new sulfonamides 4-substituted-triazolyl nucleosides

scientific article

T-Cell receptor signaling pathway exerts a negative control on thrombin-mediated increase in [Ca2+]i and p38 MAPK activation in Jurkat T cells: implication of the tyrosine kinase p56Lck.

scientific article published on June 1998

Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells

scientific article published on 9 March 2010

Targeting lysosomes to eradicate imatinib-resistant chronic myelogenous leukemia cells.

scientific article published on 8 April 2010

Targeting the Proteasome-Associated Deubiquitinating Enzyme USP14 Impairs Melanoma Cell Survival and Overcomes Resistance to MAPK-Targeting Therapies

scientific article published on 27 April 2018

The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML

scientific article

The anti-apoptotic Bcl-B protein inhibits BECN1-dependent autophagic cell death.

scientific article

The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level.

scientific article published on 21 January 2008

The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production ⬇️

scientific article published on May 4, 2012

The caspase-cleaved form of LYN mediates a psoriasis-like inflammatory syndrome in mice.

scientific article published on 09 July 2009

The cleavage of microphthalmia-associated transcription factor, MITF, by caspases plays an essential role in melanocyte and melanoma cell apoptosis

scientific article published on September 2005

The dual mTORC1 and mTORC2 inhibitor AZD8055 has anti-tumor activity in acute myeloid leukemia.

scientific article published on 6 December 2011

The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim.

scientific article published on 2 February 2018

The protective effect of phorbol esters on Fas-mediated apoptosis in T cells. Transcriptional and postranscriptional regulation.

scientific article

The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells.

scientific article

Thrombin and thrombin receptor agonist peptide induce early events of T cell activation and synergize with TCR cross-linking for CD69 expression and interleukin 2 production.

scientific article published on March 1994

Thrombin and trypsin-induced Ca(2+) mobilization in human T cell lines through interaction with different protease-activated receptors.

scientific article published on February 1996

Total genomic alteration as measured by SNP-array-based molecular karyotyping is predictive of overall survival in a cohort of MDS or AML patients treated with azacitidine.

scientific article

Transcriptome dysregulation by anthrax lethal toxin plays a key role in induction of human endothelial cell cytotoxicity

scientific article

Tumor cell-mediated induction of the stromal factor stromelysin-3 requires heterotypic cell contact-dependent activation of specific protein kinase C isoforms

scientific article

Tumor suppressor function of miR-483-3p on squamous cell carcinomas due to its pro-apoptotic properties

scientific article

Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha

scientific article published on 01 September 1996

Tyrosine phosphorylation of insulin receptor substrates during ischemia/reperfusion-induced apoptosis in rat liver.

scientific article

Ultrasound-assisted one-pot synthesis of anti-CML nucleosides featuring 1,2,3-triazole nucleobase under iron-copper catalysis.

scientific article published on 25 April 2012

When autophagy meets cancer through p62/SQSTM1.

scientific article published on 28 June 2012

[Autophagy, a key player in leukemogenesis and a therapeutic target in hematopoietic malignancies]

scientific article published on 01 March 2017

[Inhibition of apoptosis: a new therapeutic approach to prevent liver ischemia-reperfusion lesions?]

scientific article published on 01 June 2000

[Nobel prizes in medicine 2016]

scientific article published on 02 November 2016

[Roles and mechanisms of apoptosis in infectious diseases]

scientific article published on 01 September 2000

cIAPs and XIAP reduce RIPKs to silence.

scientific article

p44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1)-dependent signaling contributes to epithelial skin carcinogenesis.

scientific article published in March 2006

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