List of works - Sandrine Marchetti

A survey of the signaling pathways involved in megakaryocytic differentiation of the human K562 leukemia cell line by molecular and c-DNA array analysis.

scientific article published on February 2006

Amplification loop of the inflammatory process is induced by P2X7R activation in intestinal epithelial cells in response to neutrophil transepithelial migration

scientific article

Apoptosis and erythroid differentiation triggered by Bcr-Abl inhibitors in CML cell lines are fully distinguishable processes that exhibit different sensitivity to caspase inhibition.

scientific article published on 9 October 2006

BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic mice

scientific article published on 25 July 2016

Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis.

scientific article

Combination of glycolysis inhibition with chemotherapy results in an antitumor immune response.

scientific article

Complete structure of an increasing capillary permeability protein (ICPP) purified from Vipera lebetina venom. ICPP is angiogenic via vascular endothelial growth factor receptor signalling

scientific article

Deciphering the Role of Oncogenic MITFE318K in Senescence Delay and Melanoma Progression

scientific article

Differentiation inducing factor 3 mediates its anti-leukemic effect through ROS-dependent DRP1-mediated mitochondrial fission and induction of caspase-independent cell death

scientific article published on 24 March 2016

Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice

scientific article published on 11 January 2021

Escherichia coli α-hemolysin counteracts the anti-virulence innate immune response triggered by the Rho GTPase activating toxin CNF1 during bacteremia

scientific article

Extracellular signal-regulated kinases phosphorylate mitogen-activated protein kinase phosphatase 3/DUSP6 at serines 159 and 197, two sites critical for its proteasomal degradation

scientific article

GAPDH binds to active Akt, leading to Bcl-xL increase and escape from caspase-independent cell death.

scientific article published on 3 May 2013

GAPDH enhances the aggressiveness and the vascularization of non-Hodgkin's B lymphomas via NF-κB-dependent induction of HIF-1α.

scientific article

Glucose metabolism is inhibited by caspases upon the induction of apoptosis.

scientific article published on 4 September 2014

Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation.

scientific article published on 7 December 2009

HIF-1alpha mediates the induction of IL-8 and VEGF expression on infection with Afa/Dr diffusely adhering E. coli and promotes EMT-like behaviour

scientific article

Impact of thymidine phosphorylase surexpression on fluoropyrimidine activity and on tumour angiogenesis

scientific article

Inducible expression of a MAP kinase phosphatase-3-GFP chimera specifically blunts fibroblast growth and ras-dependent tumor formation in nude mice

scientific article published on June 2004

Inhibition of imatinib-mediated apoptosis by the caspase-cleaved form of the tyrosine kinase Lyn in chronic myelogenous leukemia cells.

scientific article published on 2 April 2009

Lysosomal Cholesterol Hydrolysis Couples Efferocytosis to Anti-Inflammatory Oxysterol Production

scientific article published on 9 March 2018

NIK promotes tissue destruction independently of the alternative NF-κB pathway through TNFR1/RIP1-induced apoptosis

scientific article published on 5 June 2015

Post-translational regulation of the ERK phosphatase DUSP6/MKP3 by the mTOR pathway.

scientific article

Severe thymic atrophy in a mouse model of skin inflammation accounts for impaired TNFR1 signaling

scientific article

Starvation and antimetabolic therapy promote cytokine release and recruitment of immune cells

scientific article published on 20 April 2020

The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML

scientific article

The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production ⬇️

scientific article published on May 4, 2012

The caspase-cleaved form of LYN mediates a psoriasis-like inflammatory syndrome in mice.

scientific article published on 09 July 2009

The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim.

scientific article published on 2 February 2018

List of works by Sandrine Marchetti

A survey of the signaling pathways involved in megakaryocytic differentiation of the human K562 leukemia cell line by molecular and c-DNA array analysis.

Amplification loop of the inflammatory process is induced by P2X7R activation in intestinal epithelial cells in response to neutrophil transepithelial migration

Apoptosis and erythroid differentiation triggered by Bcr-Abl inhibitors in CML cell lines are fully distinguishable processes that exhibit different sensitivity to caspase inhibition.

BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic mice

Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis.

Combination of glycolysis inhibition with chemotherapy results in an antitumor immune response.

Complete structure of an increasing capillary permeability protein (ICPP) purified from Vipera lebetina venom. ICPP is angiogenic via vascular endothelial growth factor receptor signalling

Deciphering the Role of Oncogenic MITFE318K in Senescence Delay and Melanoma Progression

Differentiation inducing factor 3 mediates its anti-leukemic effect through ROS-dependent DRP1-mediated mitochondrial fission and induction of caspase-independent cell death

Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice

Escherichia coli α-hemolysin counteracts the anti-virulence innate immune response triggered by the Rho GTPase activating toxin CNF1 during bacteremia

Extracellular signal-regulated kinases phosphorylate mitogen-activated protein kinase phosphatase 3/DUSP6 at serines 159 and 197, two sites critical for its proteasomal degradation

GAPDH binds to active Akt, leading to Bcl-xL increase and escape from caspase-independent cell death.

GAPDH enhances the aggressiveness and the vascularization of non-Hodgkin's B lymphomas via NF-κB-dependent induction of HIF-1α.

Glucose metabolism is inhibited by caspases upon the induction of apoptosis.

Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation.

HIF-1alpha mediates the induction of IL-8 and VEGF expression on infection with Afa/Dr diffusely adhering E. coli and promotes EMT-like behaviour

Impact of thymidine phosphorylase surexpression on fluoropyrimidine activity and on tumour angiogenesis

Inducible expression of a MAP kinase phosphatase-3-GFP chimera specifically blunts fibroblast growth and ras-dependent tumor formation in nude mice

Inhibition of imatinib-mediated apoptosis by the caspase-cleaved form of the tyrosine kinase Lyn in chronic myelogenous leukemia cells.

Lysosomal Cholesterol Hydrolysis Couples Efferocytosis to Anti-Inflammatory Oxysterol Production

NIK promotes tissue destruction independently of the alternative NF-κB pathway through TNFR1/RIP1-induced apoptosis

Post-translational regulation of the ERK phosphatase DUSP6/MKP3 by the mTOR pathway.

Severe thymic atrophy in a mouse model of skin inflammation accounts for impaired TNFR1 signaling

Starvation and antimetabolic therapy promote cytokine release and recruitment of immune cells

The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML

The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production ⬇️

The caspase-cleaved form of LYN mediates a psoriasis-like inflammatory syndrome in mice.

The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim.