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List of works by Ludmilla Morozova-Roche

A complex of equine lysozyme and oleic acid with bactericidal activity against Streptococcus pneumoniae

scientific article published on 18 November 2013

A false paradise - mixed blessings in the protein universe: the amyloid as a new challenge in drug development

scientific article published on 01 January 2007

A generic method for design of oligomer-specific antibodies.

scientific article

Abnormal pigment epithelium-derived factor processing in progressive myopia

scientific article

Aggregation of human S100A8 and S100A9 amyloidogenic proteins perturbs proteostasis in a yeast model

scientific article

Amyloid fibril formation and seeding by wild-type human lysozyme and its disease-related mutational variants.

scientific article published in June 2000

Amyloid formation by the pro-inflammatory S100A8/A9 proteins in the ageing prostate

scientific article published on 15 May 2009

Amyloid β-peptides 1-40 and 1-42 form oligomers with mixed β-sheets.

scientific article

Amyloidogenic properties of the artificial protein albebetin and its biologically active derivatives. The role of electrostatic interactions in fibril formation

scientific article published on 01 March 2006

Antibodies to Glutamate Reversed the Amnesic Effects of Proinflammatory S100A9 Protein Fibrils in Aged C57Bl/6 Mice.

scientific article published on 27 February 2017

Calcium-binding and temperature induced transitions in equine lysozyme: new insights from the pCa-temperature "phase diagrams"

scientific article published on 01 December 2006

Co-aggregation of pro-inflammatory S100A9 with α-synuclein in Parkinson's disease: ex vivo and in vitro studies.

scientific article published on 4 June 2018

Correlation between protective immunity to α-synuclein aggregates, oxidative stress and inflammation

scientific article published on 11 September 2012

Cytotoxicity of albebetin oligomers depends on cross-beta-sheet formation

scientific article published on 7 April 2006

Differential neuroimmune markers to the onset of Alzheimer's disease neurodegeneration and dementia: autoantibodies to Abeta((25-35)) oligomers, S100b and neurotransmitters.

scientific article published on 2 May 2007

Engrafting fetal liver cells into multiple tissues of healthy adult mice without the use of immunosuppressants.

scientific article published on 10 May 2007

Equine lysozyme: the molecular basis of folding, self-assembly and innate amyloid toxicity.

scientific article published on 21 May 2007

Expression and purification of active recombinant equine lysozyme in Escherichia coli.

scientific article published on 2 August 2009

Fibrillation of carrier protein albebetin and its biologically active constructs. Multiple oligomeric intermediates and pathways.

scientific article published in August 2004

Finke-Watzky Two-Step Nucleation-Autocatalysis Model of S100A9 Amyloid Formation: Protein Misfolding as "Nucleation" Event.

scientific article published on 31 July 2017

Formation of amyloid aggregates from human lysozyme and its disease-associated variants using hydrostatic pressure.

scientific article

Generic structures of cytotoxic liprotides: nano-sized complexes with oleic acid cores and shells of disordered proteins

scientific article published on 17 November 2014

Helicobacter pylori Adapts to Chronic Infection and Gastric Disease via pH-Responsive BabA-Mediated Adherence.

scientific article published on March 2017

Immunochemical Detection of α-Synuclein Autoantibodies in Parkinson's Disease: Correlation between Plasma and Cerebrospinal Fluid Levels

scientific article published on 6 March 2017

Immunoprotection against toxic biomarkers is retained during Parkinson's disease progression

scientific article published on 15 January 2011

Independent Nucleation and Heterogeneous Assembly of Structure During Folding of Equine Lysozyme

Intermediate amyloid oligomers of lysozyme: Is their cytotoxicity a particular case or general rule for amyloid?

scientific article published on May 2006

Intranasal administration of alpha-synuclein aggregates: a Parkinson's disease model with behavioral and neurochemical correlates

scientific article published on 27 January 2014

Intranasally Administered S100A9 Amyloids Induced Cellular Stress, Amyloid Seeding, and Behavioral Impairment in Aged Mice

scientific article published on 12 April 2018

Intrinsic determinants of Aβ(12-24) pH-dependent self-assembly revealed by combined computational and experimental studies.

scientific article

Is polyproline II helix the killer conformation? a raman optical activity study of the amyloidogenic prefibrillar intermediate of human lysozyme 1 1Edited by A. R. Fersht

scientific article published on 01 August 2000

Lipoprotein Complex of Equine Lysozyme with Oleic Acid (ELOA) Interactions with the Plasma Membrane of Live Cells ⬇️

scientific article published on September 21, 2010

Lysozyme Amyloid Oligomers and Fibrils Induce Cellular Death via Different Apoptotic/Necrotic Pathways

scientific article published on 03 November 2006

Nasal inoculation with α-synuclein aggregates evokes rigidity, locomotor deficits and immunity to such misfolded species as well as dopamine.

scientific article published on 17 January 2013

Natural Compound from Olive Oil Inhibits S100A9 Amyloid Formation and Cytotoxicity: Implications for Preventing Alzheimer's Disease

scientific article published on 12 May 2021

Natural and amyloid self-assembly of S100 proteins: structural basis of functional diversity.

scientific article

Noradrenergic and serotonergic neurochemistry arising from intranasal inoculation with α-synuclein aggregates which incite parkinsonian-like symptoms

scientific article published on 18 November 2014

Observation of sequence specificity in the seeding of protein amyloid fibrils.

scientific article published in July 2004

Observation of the Early Structural Changes Leading to the Formation of Protein Superstructures.

scientific article published on 9 September 2014

Pro-Inflammatory S100A9 Protein Aggregation Promoted by NCAM1 Peptide Constructs

scientific article published on 13 June 2019

Pro-inflammatory S100A8 and S100A9 proteins: self-assembly into multifunctional native and amyloid complexes

scientific article

Pro-inflammatory S100A9 Protein as a Robust Biomarker Differentiating Early Stages of Cognitive Impairment in Alzheimer's Disease

scientific article published on 9 November 2015

Proinflammatory S100A9 Regulates Differentiation and Aggregation of Neural Stem Cells

scientific article published on 20 October 2020

Protein misfolding and self‐assembly: acquired functions and their therapeutic and pathological significance ⬇️

scientific article published on 01 November 2010

S100A6 amyloid fibril formation is calcium-modulated and enhances superoxide dismutase-1 (SOD1) aggregation

scientific article

S100A8/A9 amyloidosis in the ageing prostate: relating ex vivo and in vitro studies

scientific article published on January 2012

S100A9 Protein Aggregates Boost Hippocampal Glutamate Modifying Monoaminergic Neurochemistry: A Glutamate Antibody Sensitive Outcome on Alzheimer-like Memory Decline.

scientific article

S100A9-Driven Amyloid-Neuroinflammatory Cascade in Traumatic Brain Injury as a Precursor State for Alzheimer's Disease

scientific article published in Scientific Reports

Strengthening the positions of Scandinavian science in research on neurodegenerative and age-dependent amyloid diseases

scientific article published on 01 March 2010

Structure and function of human α‐lactalbumin made lethal to tumor cells (HAMLET)‐type complexes ⬇️

scientific article published on November 1, 2010

Surface-Directed Structural Transition of Amyloidogenic Aggregates and the Resulting Neurotoxicity

scientific article published on 06 February 2020

The interaction of equine lysozyme:oleic acid complexes with lipid membranes suggests a cargo off-loading mechanism

scientific article

The misfolded pro-inflammatory protein S100A9 disrupts memory via neurochemical remodelling instigating an Alzheimer's disease-like cognitive deficit.

scientific article published on 7 March 2016

The nootropic and neuroprotective proline-containing dipeptide noopept restores spatial memory and increases immunoreactivity to amyloid in an Alzheimer's disease model.

scientific article published on 8 November 2006

The role of pro-inflammatory S100A9 in Alzheimer's disease amyloid-neuroinflammatory cascade

scientific article

Tyrosine Hydroxylase Binding to Phospholipid Membranes Prompts Its Amyloid Aggregation and Compromises Bilayer Integrity.

scientific article

Unlocked concanavalin A forms amyloid-like fibrils from coagulation of long-lived "crinkled" intermediates. ⬇️

scientific article

[Amyloid-like fibrils forming and fibroblasts destruction in Tenon's capsule in progressive myopia as a result of pigment epithelium derived factor resistance to restricted proteolysis]

scientific article published on 01 November 2012

α-synuclein reactive antibodies as diagnostic biomarkers in blood sera of Parkinson's disease patients.

scientific article

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