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List of works by Seung-Jae Lee

3-D worm tracker for freely moving C. elegans

scientific article (publication date: 2013)

A genetic screen for modifiers of Drosophila caspase Dcp-1 reveals caspase involvement in autophagy and novel caspase-related genes

scientific article

A lysosomal tetraspanin associated with retinal degeneration identified via a genome-wide screen.

scientific article published on 12 February 2004

Advances in transcriptome analysis of human brain aging

scientific article published on 26 November 2020

Age-dependent changes and biomarkers of aging in Caenorhabditis elegans

scientific article published on 08 February 2019

Beta-lapachone, a modulator of NAD metabolism, prevents health declines in aged mice

scientific article

C. elegans maximum velocity correlates with healthspan and is maintained in worms with an insulin receptor mutation

scientific article published on 20 November 2015

Caenorhabditis elegans Lipin 1 moderates the lifespan-shortening effects of dietary glucose by maintaining ω-6 polyunsaturated fatty acids

scientific article published on 31 May 2020

Combinatorial Approach Using Caenorhabditis elegans and Mammalian Systems for Aging Research

scientific article published in 2021

Diacetyl odor shortens longevity conferred by food deprivation in C. elegans via downregulation of DAF-16/FOXO

scientific article published on 31 December 2020

Direct and indirect gene regulation by a life-extending FOXO protein in C. elegans: roles for GATA factors and lipid gene regulators

scientific article published on January 2013

Dissection of C. elegans behavioral genetics in 3-D environments

scientific article

Feedback regulation via AMPK and HIF-1 mediates ROS-dependent longevity in Caenorhabditis elegans

scientific article

Genes that act downstream of sensory neurons to influence longevity, dauer formation, and pathogen responses in Caenorhabditis elegans

scientific article (publication date: 2012)

Genetic inhibition of an ATP synthase subunit extends lifespan in C. elegans

scientific article published in Scientific Reports

Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression

scientific article

Inhibition of elongin C promotes longevity and protein homeostasis via HIF-1 in C. elegans

scientific article

Inhibition of respiration extends C. elegans life span via reactive oxygen species that increase HIF-1 activity

scientific article

Inhibition of the oligosaccharyl transferase in Caenorhabditis elegans that compromises ER proteostasis suppresses p38-dependent protection against pathogenic bacteria

scientific article published on 04 March 2020

KIN-4/MAST kinase promotes PTEN-mediated longevity of Caenorhabditis elegans via binding through a PDZ domain

scientific article published on 17 February 2019

Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans

scientific article (publication date: February 2007)

Light adaptation through phosphoinositide-regulated translocation of Drosophila visual arrestin

scientific article published in July 2003

Light-dependent translocation of visual arrestin regulated by the NINAC myosin III.

scientific article published in July 2004

MDT-15/MED15 permits longevity at low temperature via enhancing lipidostasis and proteostasis

scientific article published on 13 August 2019

Meeting Report: International Symposium on the Genetics of Aging and Life History II.

scientific article

Mitochondria and organismal longevity.

scientific article

Mitochondria-mediated defense mechanisms against pathogens in Caenorhabditis elegans.

scientific article published in June 2018

Mitochondrial chaperone HSP-60 regulates anti-bacterial immunity via p38 MAP kinase signaling

scientific article

Multiplex quantitative analysis of microRNA expression via exponential isothermal amplification and conformation-sensitive DNA separation

scientific article published on 12 September 2017

Myricetin improves endurance capacity and mitochondrial density by activating SIRT1 and PGC-1α

scientific article published on 24 July 2017

Non-Coding RNAs in Caenorhabditis elegans Aging.

scientific article published in May 2019

OASIS: online application for the survival analysis of lifespan assays performed in aging research

scientific article

Precise expression profiling by stuffer-free multiplex ligation-dependent probe amplification.

scientific article published on 19 September 2013

RNA helicase HEL-1 promotes longevity by specifically activating DAF-16/FOXO transcription factor signaling in Caenorhabditis elegans

scientific article

RNA helicase SACY-1 is required for longevity caused by various genetic perturbations in Caenorhabditis elegans.

scientific article published on 06 May 2016

RNAi targeting Caenorhabditis elegans α-arrestins has little effect on lifespan

scientific article published on 18 August 2017

Regulation of life span by mitochondrial respiration: the HIF-1 and ROS connection ⬇️

scientific article published on March 1, 2011

Regulation of lifespan by chemosensory and thermosensory systems: findings in invertebrates and their implications in mammalian aging.

scientific article

Regulation of the longevity response to temperature by thermosensory neurons in Caenorhabditis elegans

scientific article

Rhodopsin kinase activity modulates the amplitude of the visual response in Drosophila

scholarly article

SREBP and MDT-15 protect C. elegans from glucose-induced accelerated aging by preventing accumulation of saturated fat

scientific article

Suppression of constant-light-induced blindness but not retinal degeneration by inhibition of the rhodopsin degradation pathway.

scientific article published in December 2004

The role of insulin/IGF-1 signaling in the longevity of model invertebrates, C. elegans and D. melanogaster

scientific article

The somatic reproductive tissues of C. elegans promote longevity through steroid hormone signaling

scientific article

Tissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegans

scholarly article

Transfer RNA-derived fragments in aging Caenorhabditis elegans originate from abundant homologous gene copies

scientific article published on 10 June 2021

VRK-1 extends life span by activation of AMPK via phosphorylation

scientific article published on 01 July 2020

Western Blot Analysis of C. elegans Proteins

scientific article published in January 2018

eIF2A, an initiator tRNA carrier refractory to eIF2α kinases, functions synergistically with eIF5B

scientific article published on 17 July 2018

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