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List of works by Grazia Graziani

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Chemopotentiation by PARP inhibitors in cancer therapy.

scientific article
Poly(ADP-ribose) polymerase (PARP) inhibition or PARP-1 gene deletion reduces angiogenesis

article
Potential clinical applications of poly(ADP-ribose) polymerase (PARP) inhibitors.

scientific article
Challenging resistance mechanisms to therapies for metastatic melanoma

scientific article published on November 7, 2013
Inhibition of poly(ADP-ribose) polymerase prevents irinotecan-induced intestinal damage and enhances irinotecan/temozolomide efficacy against colon carcinoma

scientific article published on 29 June 2006
Ipilimumab: a novel immunostimulatory monoclonal antibody for the treatment of cancer.

scientific article published on 10 September 2011
Recent approaches to improve the antitumor efficacy of temozolomide.

scientific article published on January 2009
Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to Cisplatin and poly (adp-ribose) polymerase inhibition

scientific article
EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.

scientific article published on 10 June 2016
Evidence that corticotropin-releasing hormone inhibits cell growth of human breast cancer cells via the activation of CRH-R1 receptor subtype.

scientific article published on 9 November 2006
PARP-1 modulates amyloid beta peptide-induced neuronal damage

scientific article
Doping with growth hormone/IGF-1, anabolic steroids or erythropoietin: is there a cancer risk?

scientific article published on 3 February 2007
Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide

scientific article
Combined treatment with temozolomide and poly(ADP-ribose) polymerase inhibitor enhances survival of mice bearing hematologic malignancy at the central nervous system site

scientific article published in March 2002
Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells.

scientific article published in October 2002
Cilengitide downmodulates invasiveness and vasculogenic mimicry of neuropilin 1 expressing melanoma cells through the inhibition of αvβ5 integrin.

scientific article published on 28 November 2014
Inhibition of telomerase increases resistance of melanoma cells to temozolomide, but not to temozolomide combined with poly (adp-ribose) polymerase inhibitor

scientific article published on January 2003
Neuropilin-1 as Therapeutic Target for Malignant Melanoma.

scientific article published on 03 June 2015
Glucocorticoid-induced tumor necrosis factor receptor family-related ligand triggering upregulates vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 and promotes leukocyte adhesion

scientific article
Role of BRCA Mutations in Cancer Treatment with Poly(ADP-ribose) Polymerase (PARP) Inhibitors

scientific article published on 04 December 2018
Inhibition of O6-alkylguanine DNA-alkyltransferase or poly(ADP-ribose) polymerase increases susceptibility of leukemic cells to apoptosis induced by temozolomide

scientific article published on 01 August 1997
Therapeutic implication of vascular endothelial growth factor receptor-1 (VEGFR-1) targeting in cancer cells and tumor microenvironment by competitive and non-competitive inhibitors

scientific article published on 28 August 2018
Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant.

scientific article published on 18 September 2009
Exploiting Microglial Functions for the Treatment of Glioblastoma.

scientific article published on 13 August 2016
NF-κB is activated in response to temozolomide in an AKT-dependent manner and confers protection against the growth suppressive effect of the drug

scientific article published on 21 December 2012
A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib

scientific article
The glutathione transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) increases temozolomide efficacy against malignant melanoma.

scientific article published on 25 January 2011
Poly(ADP-ribose) glycohydrolase inhibitor as chemosensitiser of malignant melanoma for temozolomide

scientific article published on 8 November 2005
Ellagic Acid Inhibits Bladder Cancer Invasiveness and In Vivo Tumor Growth

scientific article
Influence of Mycobacterium bovis bacillus Calmette Guérin on in vitro induction of CD1 molecules in human adherent mononuclear cells

scientific article
Effects of single or split exposure of leukemic cells to temozolomide, combined with poly(ADP-ribose) polymerase inhibitors on cell growth, chromosomal aberrations and base excision repair components.

scientific article published on April 2001
Expression of the soluble vascular endothelial growth factor receptor-1 in cutaneous melanoma: role in tumour progression.

scientific article published on May 2011
The anti-vascular endothelial growth factor receptor-1 monoclonal antibody D16F7 inhibits invasiveness of human glioblastoma and glioblastoma stem cells

scientific article published on 10 August 2017
Platelet-derived growth factor C and calpain-3 are modulators of human melanoma cell invasiveness.

scientific article published on 10 October 2013
High-dose ascorbate and arsenic trioxide selectively kill acute myeloid leukemia and acute promyelocytic leukemia blasts in vitro

scientific article published on 6 March 2017
Combined effects of adenovirus-mediated wild-type p53 transduction, temozolomide and poly (ADP-ribose) polymerase inhibitor in mismatch repair deficient and non-proliferating tumor cells.

scientific article published on May 2001
Placenta growth factor and neuropilin-1 collaborate in promoting melanoma aggressiveness.

scientific article published on 29 January 2016
Experimental Evidence of the Antitumor, Antimetastatic and Antiangiogenic Activity of Ellagic Acid

scientific article published on 14 November 2018
MSH3 expression does not influence the sensitivity of colon cancer HCT116 cell line to oxaliplatin and poly(ADP-ribose) polymerase (PARP) inhibitor as monotherapy or in combination.

scientific article published on May 2013
Poly(ADP-ribose) polymerase signaling of topoisomerase 1-dependent DNA damage in carcinoma cells.

scientific article published on 25 September 2010
Inhibition of endothelial cell migration and angiogenesis by a vascular endothelial growth factor receptor-1 derived peptide.

scientific article published on 3 August 2008
Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome

scientific article published on 14 January 2017
Primary cultures of microglial cells for testing toxicity of anticancer drugs.

scientific article published in March 2004
PARP Inhibitors in Cancer Therapy: Magic Bullets but Moving Targets

scientific article
PARP-1 inhibition to treat cancer, ischemia, inflammation

scientific article published on 01 July 2005
Pharmacological inhibition of poly(ADP-ribose) polymerase activity down-regulates the expression of syndecan-4 and Id-1 in endothelial cells.

scientific article
Cytokine-induced expression of CD1b molecules by peripheral blood monocytes: influence of 3'-azido-3'-deoxythymidine.

scientific article published in February 1997
Effect of rifampin on CD1b expression and double-negative T cell responses against mycobacteria-derived glycolipid antigen.

scientific article published on January 1998
Apoptotic and genotoxic effects of a methyl sulfonate ester that selectively generates N3-methyladenine and poly(ADP-ribose) polymerase inhibitors in normal peripheral blood lymphocytes.

scientific article
Common fragile sites in colon cancer cell lines: Role of mismatch repair, RAD51 and poly(ADP-ribose) polymerase-1

scientific article published on May 5, 2011

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