List of works by Grazia Graziani

A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib

scientific article

Antitumor activity of a novel anti-vascular endothelial growth factor receptor-1 monoclonal antibody that does not interfere with ligand binding

scientific article published on 19 September 2016

Apoptotic and genotoxic effects of a methyl sulfonate ester that selectively generates N3-methyladenine and poly(ADP-ribose) polymerase inhibitors in normal peripheral blood lymphocytes.

scientific article

BCG-infected adherent mononuclear cells release cytokines that regulate group 1 CD1 molecule expression

scientific article published on 8 December 2006

Beneficial and Detrimental Effects of Antiretroviral Therapy on HIV-Associated Immunosenescence.

scientific article published on 13 March 2018

Challenging resistance mechanisms to therapies for metastatic melanoma.

scientific article

Chemopotentiation by PARP inhibitors in cancer therapy.

scientific article

Cilengitide downmodulates invasiveness and vasculogenic mimicry of neuropilin 1 expressing melanoma cells through the inhibition of αvβ5 integrin.

scientific article published on 28 November 2014

Combined effects of adenovirus-mediated wild-type p53 transduction, temozolomide and poly (ADP-ribose) polymerase inhibitor in mismatch repair deficient and non-proliferating tumor cells.

scientific article published on May 2001

Combined treatment with temozolomide and poly(ADP-ribose) polymerase inhibitor enhances survival of mice bearing hematologic malignancy at the central nervous system site

scientific article published in March 2002

Cytokine-induced expression of CD1b molecules by peripheral blood monocytes: influence of 3'-azido-3'-deoxythymidine.

scientific article published in February 1997

Cytotoxicity and Differentiating Effect of the Poly(ADP-Ribose) Polymerase Inhibitor Olaparib in Myelodysplastic Syndromes

scientific article published on 16 September 2019

Doping with growth hormone/IGF-1, anabolic steroids or erythropoietin: is there a cancer risk?

scientific article published on 3 February 2007

Drug-induced xenogenization of tumors: A possible role in the immune control of malignant cell growth in the brain?

scientific article published on 09 March 2018

EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.

scientific article published on 10 June 2016

Editorial

scientific article published on 03 November 2015

Effect of hydrocortisone on human natural killer activity and its modulation by beta interferon

scientific article published on 01 January 1988

Effect of rifampin on CD1b expression and double-negative T cell responses against mycobacteria-derived glycolipid antigen.

scientific article published on January 1998

Effects of single or split exposure of leukemic cells to temozolomide, combined with poly(ADP-ribose) polymerase inhibitors on cell growth, chromosomal aberrations and base excision repair components.

scientific article published on April 2001

Ellagic Acid Inhibits Bladder Cancer Invasiveness and In Vivo Tumor Growth

scientific article

Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant.

scientific article published on 18 September 2009

Evidence that corticotropin-releasing hormone inhibits cell growth of human breast cancer cells via the activation of CRH-R1 receptor subtype.

scientific article published on 9 November 2006

Experimental Evidence of the Antitumor, Antimetastatic and Antiangiogenic Activity of Ellagic Acid

scientific article published on 14 November 2018

Exploiting Microglial Functions for the Treatment of Glioblastoma.

scientific article published on 13 August 2016

Expression of the soluble vascular endothelial growth factor receptor-1 in cutaneous melanoma: role in tumour progression.

scientific article published on May 2011

Glucocorticoid-induced tumor necrosis factor receptor family-related ligand triggering upregulates vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 and promotes leukocyte adhesion

scientific article

High-dose ascorbate and arsenic trioxide selectively kill acute myeloid leukemia and acute promyelocytic leukemia blasts in vitro

scientific article published on 6 March 2017

In vitro combined effects of human interferons and interleukin-2 on natural cell-mediated cytotoxicity ⬇️

scientific article published on January 1, 1993

Influence of MLH1 on colon cancer sensitivity to poly(ADP-ribose) polymerase inhibitor combined with irinotecan.

scientific article published on 8 May 2013

Influence of Mycobacterium bovis bacillus Calmette Guérin on in vitro induction of CD1 molecules in human adherent mononuclear cells

scientific article

Inhibition of O6-alkylguanine DNA-alkyltransferase or poly(ADP-ribose) polymerase increases susceptibility of leukemic cells to apoptosis induced by temozolomide

scientific article published on 01 August 1997

Inhibition of endothelial cell migration and angiogenesis by a vascular endothelial growth factor receptor-1 derived peptide.

scientific article published on 3 August 2008

Inhibition of homologous recombination by treatment with BVDU (brivudin) or by RAD51 silencing increases chromosomal damage induced by bleomycin in mismatch repair-deficient tumour cells.

scientific article

Inhibition of poly(ADP-ribose) polymerase prevents irinotecan-induced intestinal damage and enhances irinotecan/temozolomide efficacy against colon carcinoma

scientific article published on 29 June 2006

Inhibition of telomerase increases resistance of melanoma cells to temozolomide, but not to temozolomide combined with poly (adp-ribose) polymerase inhibitor

scientific article published on January 2003

Ipilimumab: a novel immunostimulatory monoclonal antibody for the treatment of cancer.

scientific article published on 10 September 2011

Lead Discovery of Dual G-Quadruplex Stabilizers and Poly(ADP-ribose) Polymerases (PARPs) Inhibitors: A New Avenue in Anticancer Treatment.

scientific article

MSH3 expression does not influence the sensitivity of colon cancer HCT116 cell line to oxaliplatin and poly(ADP-ribose) polymerase (PARP) inhibitor as monotherapy or in combination.

scientific article published on May 2013

Modulation of GDF11 expression and synaptic plasticity by age and training

scientific article published on 3 August 2017

Mutations of human DNA topoisomerase I at poly(ADP-ribose) binding sites: modulation of camptothecin activity by ADP-ribose polymers

scientific article

N3-methyladenine induces early poly(ADP-ribosylation), reduction of nuclear factor-kappa B DNA binding ability, and nuclear up-regulation of telomerase activity.

scientific article

NF-κB is activated in response to temozolomide in an AKT-dependent manner and confers protection against the growth suppressive effect of the drug

scientific article published on 21 December 2012

Neuropilin-1 as Therapeutic Target for Malignant Melanoma.

scientific article published on 03 June 2015

Neuropilin-1 expressing melanoma cells as a model to study the aggressiveness of metastatic melanoma.

scientific article published on 15 January 2015

On the Horizon: Targeting Next-Generation Immune Checkpoints for Cancer Treatment

scientific article published on 06 August 2019

PARP Inhibitors in Cancer Therapy: Magic Bullets but Moving Targets

scientific article

PARP-1 inhibition to treat cancer, ischemia, inflammation

scientific article published on 01 July 2005

PARP-1 modulates amyloid beta peptide-induced neuronal damage

scientific article

PDIA3 Expression in Glioblastoma Modulates Macrophage/Microglia Pro-Tumor Activation

scientific article published on 03 November 2020

Pharmacological inhibition of poly(ADP-ribose) polymerase activity down-regulates the expression of syndecan-4 and Id-1 in endothelial cells.

scientific article

Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide

scientific article

Placenta growth factor and neuropilin-1 collaborate in promoting melanoma aggressiveness.

scientific article published on 29 January 2016

Platelet-derived growth factor C and calpain-3 are modulators of human melanoma cell invasiveness.

scientific article published on 10 October 2013

Poly(ADP-ribose) glycohydrolase inhibitor as chemosensitiser of malignant melanoma for temozolomide

scientific article published on 8 November 2005

Poly(ADP-ribose) polymerase (PARP) inhibition or PARP-1 gene deletion reduces angiogenesis

article

Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells.

scientific article published in October 2002

Poly(ADP-ribose) polymerase inhibitor olaparib hampers placental growth factor-driven activation of myelomonocytic cells.

scientific article published on 5 March 2018

Poly(ADP-ribose) polymerase signaling of topoisomerase 1-dependent DNA damage in carcinoma cells.

scientific article published on 25 September 2010

Potential clinical applications of poly(ADP-ribose) polymerase (PARP) inhibitors.

scientific article

Primary cultures of microglial cells for testing toxicity of anticancer drugs.

scientific article published in March 2004

Recent approaches to improve the antitumor efficacy of temozolomide.

scientific article published on January 2009

Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to Cisplatin and poly (adp-ribose) polymerase inhibition

scientific article

Role of BRCA Mutations in Cancer Treatment with Poly(ADP-ribose) Polymerase (PARP) Inhibitors

scientific article published on 04 December 2018

Role of VEGFR-1 in melanoma acquired resistance to the BRAF inhibitor vemurafenib

scientific article published on 23 November 2019

Role of the mismatch repair system and p53 in the clastogenicity and cytotoxicity induced by bleomycin.

scientific article published on September 2005

Targeting ADP-ribosylation by PARP inhibitors in acute myeloid leukaemia and related disorders

scientific article published on 24 April 2019

Targeting Tumor-Associated Macrophages to Increase the Efficacy of Immune Checkpoint Inhibitors: A Glimpse into Novel Therapeutic Approaches for Metastatic Melanoma

scientific article published on 17 November 2020

Telomerase as a potential anticancer target: growth inhibition and genomic instability.

scientific article

The Anti-Vascular Endothelial Growth Factor Receptor-1 Monoclonal Antibody D16F7 Inhibits Glioma Growth and Angiogenesis In Vivo.

scientific article

The anti-vascular endothelial growth factor receptor-1 monoclonal antibody D16F7 inhibits invasiveness of human glioblastoma and glioblastoma stem cells

scientific article published on 10 August 2017

The glutathione transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) increases temozolomide efficacy against malignant melanoma.

scientific article published on 25 January 2011

The poly(ADP-ribose) polymerase inhibitor olaparib induces up-regulation of death receptors in primary acute myeloid leukemia blasts by NF-κB activation

scientific article published on 08 March 2018

Therapeutic implication of vascular endothelial growth factor receptor-1 (VEGFR-1) targeting in cancer cells and tumor microenvironment by competitive and non-competitive inhibitors

scientific article published on 28 August 2018

Treatment of peripheral blood with staurosporine increases detection of circulating carcinoembryonic antigen positive tumor cells.

scientific article

Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome

scientific article published on 14 January 2017

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