List of works - T Yau

11C-acetate and 18F-FDG PET/CT for clinical staging and selection of patients with hepatocellular carcinoma for liver transplantation on the basis of Milan criteria: surgeon's perspective

scientific article published on 15 January 2013

A Phase I/II Multicenter Study of Single-Agent Foretinib as First-Line Therapy in Patients with Advanced Hepatocellular Carcinoma

scientific article published on 7 November 2016

A case of mixed adult Wilms' tumour and angiosarcoma responsive to carboplatin, etoposide and vincristine (CEO).

scientific article published on 15 June 2007

A new prognostic score system in patients with advanced hepatocellular carcinoma not amendable to locoregional therapy: implication for patient selection in systemic therapy trials.

scientific article

A phase 1 dose-escalating study of pegylated recombinant human arginase 1 (Peg-rhArg1) in patients with advanced hepatocellular carcinoma.

scientific article published on 17 March 2012

Acute presentation of rheumatoid arthritis following cancer chemotherapy using the topoisomerase I inhibitor irinotecan.

scientific article

Advanced pancreatic cancer: flourishing novel approaches in the era of biological therapy.

scientific article

Analysis of long-term survival after hepatectomy for isolated liver metastasis of gastrointestinal stromal tumour.

scientific article

Androgen deprivation therapy and cardiovascular risk in chinese patients with nonmetastatic carcinoma of prostate

scientific article

Breast and pelvic masses in a myeloma patient

scientific article published on 25 June 2008

Clonal Evolutionary Analysis during HER2 Blockade in HER2-Positive Inflammatory Breast Cancer: A Phase II Open-Label Clinical Trial of Afatinib +/- Vinorelbine

scientific article

Coexisting ductal carcinoma in situ independently predicts lower tumor aggressiveness in node-positive luminal breast cancer

scientific article

Common malignancies with uncommon sites of presentation: case 2. Mantle-cell lymphoma of the prostate.

scientific article

Complications of traditional Chinese/herbal medicines (TCM)--a guide for perplexed oncologists and other cancer caregivers.

scientific article

Development of Hong Kong Liver Cancer staging system with treatment stratification for patients with hepatocellular carcinoma.

scientific article

Does hepatitis B seroconversion affect survival outcome in patients with hepatitis B related hepatocellular carcinoma?

scientific article published on 14 June 2016

Efficacy and tolerability of low-dose thalidomide as first-line systemic treatment of patients with advanced hepatocellular carcinoma.

scientific article

Efficacy, Tolerability, and Biomarker Analyses of Once-Every-2-Weeks Cetuximab Plus First-Line FOLFOX or FOLFIRI in Patients With KRAS or All RAS Wild-Type Metastatic Colorectal Cancer: The Phase 2 APEC Study

scientific article

Family-Specific Training Improves Linear B Cell Epitope Prediction for Emerging Viruses

scientific article published on 04 September 2023

Genomic profiling of intrahepatic cholangiocarcinoma: refining prognosis and identifying therapeutic targets

scientific article

High-intensity focused ultrasound as a treatment for colorectal liver metastasis in difficult position ⬇️

scientific article published on August 13, 2011

Hoarseness during treatment with bevacizumab and other vascular endothelial growth factor signalling inhibitors

scientific article published on 01 January 2009

Hong Kong Consensus Statements for the Management of Unresectable Hepatocellular Carcinoma.

scientific article

Hong Kong consensus recommendations on the management of hepatocellular carcinoma

scientific article published on March 2015

Identification of serum miR-139-3p as a non-invasive biomarker for colorectal cancer.

scientific article

Incidence, pattern and timing of brain metastases among patients with advanced breast cancer treated with trastuzumab

scientific article published in January 2006

Initial experience with the Oncotype DX assay in decision-making for adjuvant therapy of early oestrogen receptor-positive breast cancer in Hong Kong

scientific article published on 20 June 2014

Integrating molecular mechanisms and clinical evidence in the management of trastuzumab resistant or refractory HER-2⁺ metastatic breast cancer.

scientific article published on 21 October 2011

Intramuscular recurrence in a hepatocellular carcinoma patient with indolent disease course.

scientific article

Lobular breast cancers lack the inverse relationship between ER/PR status and cell growth rate characteristic of ductal cancers in two independent patient cohorts: implications for tumor biology and adjuvant therapy

scientific article

Long term survival analysis of hepatectomy for neuroendocrine tumour liver metastases.

scientific article

Longitudinal assessment of quality of life in rectal cancer patients with or without stomas following primary resection.

scientific article published in April 2009

Management of colon cancer: resource-stratified guidelines from the Asian Oncology Summit 2012.

scientific article

Management of spontaneously ruptured hepatocellular carcinomas in the radiofrequency ablation era.

scientific article

Massive rectal bleeding in a patient with a history of hepatocellular carcinoma

scientific article published on 01 October 2008

Metastatic Pancreatic Cancer: Are We Making Progress in Treatment? ⬇️

scientific article published on December 4, 2012

Molecular targeted therapies in advanced gastric cancer: does tumor histology matter?

scientific article published on January 2013

Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial

scientific article published on 20 April 2017

Osteopontin Overexpression Induced Tumor Progression and Chemoresistance to Oxaliplatin through Induction of Stem-Like Properties in Human Colorectal Cancer

scientific article published on 27 May 2015

Outcome of laparoscopic versus open hepatectomy for colorectal liver metastases

scientific article published on 04 October 2012

PPI-delayed diagnosis of gastrinoma: oncologic victim of pharmacologic success.

scientific article

Pembrolizumab (Keytruda)

scientific article published on 11 July 2016

Phase 1-2 trial of PTK787/ZK222584 combined with intravenous doxorubicin for treatment of patients with advanced hepatocellular carcinoma: implication for antiangiogenic approach to hepatocellular carcinoma.

scientific article published on November 2010

Phase 2 open-label study of single-agent sorafenib in treating advanced hepatocellular carcinoma in a hepatitis B-endemic Asian population: presence of lung metastasis predicts poor response.

scientific article

Phase I Dose-Finding Study of Pazopanib in Hepatocellular Carcinoma: Evaluation of Early Efficacy, Pharmacokinetics, and Pharmacodynamics

scientific article published on 10 August 2011

Phase I study investigating everolimus combined with sorafenib in patients with advanced hepatocellular carcinoma

scientific article

Phase II study of bevacizumab and erlotinib in the treatment of advanced hepatocellular carcinoma patients with sorafenib-refractory disease ⬇️

scientific article published on March 9, 2012

Post-operative plasma osteopontin predicts distant metastasis in human colorectal cancer

scientific article published on 11 May 2015

Preclinical analysis of the anti-tumor and anti-metastatic effects of Raf265 on colon cancer cells and CD26(+) cancer stem cells in colorectal carcinoma

scientific article

Preemptive adefovir versus lamivudine for prevention of hepatitis B reactivation in chronic hepatitis B patients undergoing chemotherapy.

scientific article

Preliminary efficacy, safety, pharmacokinetics, pharmacodynamics and quality of life study of pegylated recombinant human arginase 1 in patients with advanced hepatocellular carcinoma

scientific article published on 10 February 2015

Presence of an in situ component is associated with reduced biological aggressiveness of size-matched invasive breast cancer.

scientific article

Prognostic significance of CD26 in patients with colorectal cancer

scientific article

Randomized phase II study of axitinib versus placebo plus best supportive care in second-line treatment of advanced hepatocellular carcinoma.

scientific article published on 18 September 2015

Regorafenib plus best supportive care versus placebo plus best supportive care in Asian patients with previously treated metastatic colorectal cancer (CONCUR): a randomised, double-blind, placebo-controlled, phase 3 trial

scientific article published on 13 May 2015

Retrospective study of metachronous lung metastases from primary hepatocellular carcinoma

scientific article published on 29 September 2014

Review article: current management of metastatic colorectal cancer - the evolving impact of targeted drug therapies.

scientific article published on 20 March 2008

Suppression of Slit3 induces tumor proliferation and chemoresistance in hepatocellular carcinoma through activation of GSK3β/β-catenin pathway.

scientific article

Suppression of actopaxin impairs hepatocellular carcinoma metastasis through modulation of cell migration and invasion.

scientific article published on August 2013

Surveillance in stage I seminoma patients: a long-term assessment.

scientific article

Survival analysis of high-intensity focused ultrasound ablation in patients with small hepatocellular carcinoma

scientific article

Survival analysis of high-intensity focused ultrasound therapy vs. transarterial chemoembolization for unresectable hepatocellular carcinomas

scientific article published on 14 February 2014

Survivin depletion inhibits tumor growth and enhances chemosensitivity in hepatocellular carcinoma.

scientific article

Targeted therapy in the management of advanced gastric cancer: are we making progress in the era of personalized medicine?

scientific article published on 14 February 2012

The Enhanced metastatic potential of hepatocellular carcinoma (HCC) cells with sorafenib resistance

scientific article

The Impact of the Oncotype DX Breast Cancer Assay on Treatment Decisions for Women With Estrogen Receptor-Positive, Node-Negative Breast Carcinoma in Hong Kong.

scientific article

The clinicopathological significance of miR-133a in colorectal cancer

scientific article published in July 2014

The ophthalmological complications of targeted agents in cancer therapy: what do we need to know as ophthalmologists?

scientific article

The real-world use of regorafenib for metastatic colorectal cancer: multicentre analysis of treatment pattern and outcomes in Hong Kong.

scientific article published on 11 November 2016

The significance of early alpha-fetoprotein level changes in predicting clinical and survival benefits in advanced hepatocellular carcinoma patients receiving sorafenib

scientific article published on September 2011

The use of single-agent sorafenib in the treatment of advanced hepatocellular carcinoma patients with underlying Child-Pugh B liver cirrhosis: a retrospective analysis of efficacy, safety, and survival benefits

scientific article

Tolerance of high-intensity focused ultrasound ablation in patients with hepatocellular carcinoma

scientific article

Trans-arterial chemo-embolization is safe and effective for elderly advanced hepatocellular carcinoma patients: results from an international database.

scientific article

Transient carcinoembryonic antigen elevations during adjuvant chemotherapy for colorectal cancer reflect the burden of residual micrometastatic disease

scientific article published on 01 April 2010

Treatment outcomes in anaplastic thyroid carcinoma: survival improvement in young patients with localized disease treated by combination of surgery and radiotherapy

scientific article published on 26 June 2008

What determines treatment success and future perspectives?

scientific article published in March 2016

List of works by T Yau

11C-acetate and 18F-FDG PET/CT for clinical staging and selection of patients with hepatocellular carcinoma for liver transplantation on the basis of Milan criteria: surgeon's perspective

A Phase I/II Multicenter Study of Single-Agent Foretinib as First-Line Therapy in Patients with Advanced Hepatocellular Carcinoma

A case of mixed adult Wilms' tumour and angiosarcoma responsive to carboplatin, etoposide and vincristine (CEO).

A new prognostic score system in patients with advanced hepatocellular carcinoma not amendable to locoregional therapy: implication for patient selection in systemic therapy trials.

A phase 1 dose-escalating study of pegylated recombinant human arginase 1 (Peg-rhArg1) in patients with advanced hepatocellular carcinoma.

Acute presentation of rheumatoid arthritis following cancer chemotherapy using the topoisomerase I inhibitor irinotecan.

Advanced pancreatic cancer: flourishing novel approaches in the era of biological therapy.

Analysis of long-term survival after hepatectomy for isolated liver metastasis of gastrointestinal stromal tumour.

Androgen deprivation therapy and cardiovascular risk in chinese patients with nonmetastatic carcinoma of prostate

Breast and pelvic masses in a myeloma patient

Clonal Evolutionary Analysis during HER2 Blockade in HER2-Positive Inflammatory Breast Cancer: A Phase II Open-Label Clinical Trial of Afatinib +/- Vinorelbine

Coexisting ductal carcinoma in situ independently predicts lower tumor aggressiveness in node-positive luminal breast cancer

Common malignancies with uncommon sites of presentation: case 2. Mantle-cell lymphoma of the prostate.

Complications of traditional Chinese/herbal medicines (TCM)--a guide for perplexed oncologists and other cancer caregivers.

Development of Hong Kong Liver Cancer staging system with treatment stratification for patients with hepatocellular carcinoma.

Does hepatitis B seroconversion affect survival outcome in patients with hepatitis B related hepatocellular carcinoma?

Efficacy and tolerability of low-dose thalidomide as first-line systemic treatment of patients with advanced hepatocellular carcinoma.

Efficacy, Tolerability, and Biomarker Analyses of Once-Every-2-Weeks Cetuximab Plus First-Line FOLFOX or FOLFIRI in Patients With KRAS or All RAS Wild-Type Metastatic Colorectal Cancer: The Phase 2 APEC Study

Family-Specific Training Improves Linear B Cell Epitope Prediction for Emerging Viruses

Genomic profiling of intrahepatic cholangiocarcinoma: refining prognosis and identifying therapeutic targets

High-intensity focused ultrasound as a treatment for colorectal liver metastasis in difficult position ⬇️

Hoarseness during treatment with bevacizumab and other vascular endothelial growth factor signalling inhibitors

Hong Kong Consensus Statements for the Management of Unresectable Hepatocellular Carcinoma.

Hong Kong consensus recommendations on the management of hepatocellular carcinoma

Identification of serum miR-139-3p as a non-invasive biomarker for colorectal cancer.

Incidence, pattern and timing of brain metastases among patients with advanced breast cancer treated with trastuzumab

Initial experience with the Oncotype DX assay in decision-making for adjuvant therapy of early oestrogen receptor-positive breast cancer in Hong Kong

Integrating molecular mechanisms and clinical evidence in the management of trastuzumab resistant or refractory HER-2⁺ metastatic breast cancer.

Intramuscular recurrence in a hepatocellular carcinoma patient with indolent disease course.

Lobular breast cancers lack the inverse relationship between ER/PR status and cell growth rate characteristic of ductal cancers in two independent patient cohorts: implications for tumor biology and adjuvant therapy

Long term survival analysis of hepatectomy for neuroendocrine tumour liver metastases.

Longitudinal assessment of quality of life in rectal cancer patients with or without stomas following primary resection.

Management of colon cancer: resource-stratified guidelines from the Asian Oncology Summit 2012.

Management of spontaneously ruptured hepatocellular carcinomas in the radiofrequency ablation era.

Massive rectal bleeding in a patient with a history of hepatocellular carcinoma

Metastatic Pancreatic Cancer: Are We Making Progress in Treatment? ⬇️

Molecular targeted therapies in advanced gastric cancer: does tumor histology matter?

Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial

Osteopontin Overexpression Induced Tumor Progression and Chemoresistance to Oxaliplatin through Induction of Stem-Like Properties in Human Colorectal Cancer

Outcome of laparoscopic versus open hepatectomy for colorectal liver metastases

PPI-delayed diagnosis of gastrinoma: oncologic victim of pharmacologic success.

Pembrolizumab (Keytruda)

Phase 1-2 trial of PTK787/ZK222584 combined with intravenous doxorubicin for treatment of patients with advanced hepatocellular carcinoma: implication for antiangiogenic approach to hepatocellular carcinoma.

Phase 2 open-label study of single-agent sorafenib in treating advanced hepatocellular carcinoma in a hepatitis B-endemic Asian population: presence of lung metastasis predicts poor response.

Phase I Dose-Finding Study of Pazopanib in Hepatocellular Carcinoma: Evaluation of Early Efficacy, Pharmacokinetics, and Pharmacodynamics

Phase I study investigating everolimus combined with sorafenib in patients with advanced hepatocellular carcinoma

Phase II study of bevacizumab and erlotinib in the treatment of advanced hepatocellular carcinoma patients with sorafenib-refractory disease ⬇️

Post-operative plasma osteopontin predicts distant metastasis in human colorectal cancer

Preclinical analysis of the anti-tumor and anti-metastatic effects of Raf265 on colon cancer cells and CD26(+) cancer stem cells in colorectal carcinoma

Preemptive adefovir versus lamivudine for prevention of hepatitis B reactivation in chronic hepatitis B patients undergoing chemotherapy.

Preliminary efficacy, safety, pharmacokinetics, pharmacodynamics and quality of life study of pegylated recombinant human arginase 1 in patients with advanced hepatocellular carcinoma

Presence of an in situ component is associated with reduced biological aggressiveness of size-matched invasive breast cancer.

Prognostic significance of CD26 in patients with colorectal cancer

Randomized phase II study of axitinib versus placebo plus best supportive care in second-line treatment of advanced hepatocellular carcinoma.

Regorafenib plus best supportive care versus placebo plus best supportive care in Asian patients with previously treated metastatic colorectal cancer (CONCUR): a randomised, double-blind, placebo-controlled, phase 3 trial

Retrospective study of metachronous lung metastases from primary hepatocellular carcinoma

Review article: current management of metastatic colorectal cancer - the evolving impact of targeted drug therapies.

Suppression of Slit3 induces tumor proliferation and chemoresistance in hepatocellular carcinoma through activation of GSK3β/β-catenin pathway.

Suppression of actopaxin impairs hepatocellular carcinoma metastasis through modulation of cell migration and invasion.

Surveillance in stage I seminoma patients: a long-term assessment.

Survival analysis of high-intensity focused ultrasound ablation in patients with small hepatocellular carcinoma

Survival analysis of high-intensity focused ultrasound therapy vs. transarterial chemoembolization for unresectable hepatocellular carcinomas

Survivin depletion inhibits tumor growth and enhances chemosensitivity in hepatocellular carcinoma.

Targeted therapy in the management of advanced gastric cancer: are we making progress in the era of personalized medicine?

The Enhanced metastatic potential of hepatocellular carcinoma (HCC) cells with sorafenib resistance

The Impact of the Oncotype DX Breast Cancer Assay on Treatment Decisions for Women With Estrogen Receptor-Positive, Node-Negative Breast Carcinoma in Hong Kong.

The clinicopathological significance of miR-133a in colorectal cancer

The ophthalmological complications of targeted agents in cancer therapy: what do we need to know as ophthalmologists?

The real-world use of regorafenib for metastatic colorectal cancer: multicentre analysis of treatment pattern and outcomes in Hong Kong.

The significance of early alpha-fetoprotein level changes in predicting clinical and survival benefits in advanced hepatocellular carcinoma patients receiving sorafenib

The use of single-agent sorafenib in the treatment of advanced hepatocellular carcinoma patients with underlying Child-Pugh B liver cirrhosis: a retrospective analysis of efficacy, safety, and survival benefits

Tolerance of high-intensity focused ultrasound ablation in patients with hepatocellular carcinoma

Trans-arterial chemo-embolization is safe and effective for elderly advanced hepatocellular carcinoma patients: results from an international database.

Transient carcinoembryonic antigen elevations during adjuvant chemotherapy for colorectal cancer reflect the burden of residual micrometastatic disease

Treatment outcomes in anaplastic thyroid carcinoma: survival improvement in young patients with localized disease treated by combination of surgery and radiotherapy

What determines treatment success and future perspectives?