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List of works by Alessio Peracchi

A core folding model for catalysis by the hammerhead ribozyme accounts for its extraordinary sensitivity to abasic mutations.

scientific article

A genomic overview of pyridoxal-phosphate-dependent enzymes

scientific article

A mutational analysis of the 8-17 deoxyribozyme core

scientific article published on 01 September 2005

A subfamily of PLP-dependent enzymes specialized in handling terminal amines

scientific article published on 12 March 2015

A threonine synthase homolog from a mammalian genome

scientific article

ATP binding to human serine racemase is cooperative and modulated by glycine

scientific article

An aminotransferase branch point connects purine catabolism to amino acid recycling.

scientific article published on 19 September 2010

Catalysis and electron transfer in protein crystals: the binary and ternary complexes of methylamine dehydrogenase with electron acceptors

scientific article published in April 2003

Characterization of tryptophan and coenzyme luminescence in tryptophan synthase from Salmonella typhimurium

scientific article published on August 25, 1992

Completing the folate biosynthesis pathway in Plasmodium falciparum: p-aminobenzoate is produced by a highly divergent promiscuous aminodeoxychorismate lyase

scientific article (publication date: 15 October 2013)

Conformational changes and subunit communication in tryptophan synthase: effect of substrates and substrate analogs

scientific article published on August 25, 1992

DNA catalysis: potential, limitations, open questions

scientific article

Deciphering the role of recurrent FAD-dependent enzymes in bacterial phosphonate catabolism

scientific article published in 2023

Discovery of a New, Recurrent Enzyme in Bacterial Phosphonate Degradation: (<i>R</i>)-1-Hydroxy-2-aminoethylphosphonate Ammonia-lyase

scientific article published on 08 April 2021

Dissecting the hybridization of oligonucleotides to structured complementary sequences

scientific article

Domain organization of phytochelatin synthase: functional properties of truncated enzyme species identified by limited proteolysis

scientific article

Effect of pH and Monovalent Cations on the Formation of Quinonoid Intermediates of the Tryptophan Synthase α2β2Complex in Solution and in the Crystal

scientific article published in Journal of Biological Chemistry

Efficient and selective cleavage of RNA oligonucleotides by calix[4]arene-based synthetic metallonucleases.

scientific article

Enzyme catalysis: removing chemically 'essential' residues by site-directed mutagenesis.

scientific article

Exploring and exploiting allostery: Models, evolution, and drug targeting

scientific article published on 28 October 2010

Insights into DNA catalysis from structural and functional studies of the 8-17 DNAzyme

scientific article published on 01 March 2020

Involvement of a specific metal ion in the transition of the hammerhead ribozyme to its catalytic conformation.

scientific article published in October 1997

Kinetic and thermodynamic characterization of the RNA-cleaving 8-17 deoxyribozyme

scientific article published on 12 February 2004

Kinetic characterization of the human O-phosphoethanolamine phospho-lyase reveals unconventional features of this specialized pyridoxal phosphate-dependent lyase.

scientific article published on 14 November 2014

Local conformational changes in the 8-17 deoxyribozyme core induced by activating and inactivating divalent metal ions

scientific article published on 12 October 2017

Nit1 is a metabolite repair enzyme that hydrolyzes deaminated glutathione

scientific article

Off to a slow start: Analyzing lag phases and accelerating rates in steady-state enzyme kinetics

scientific article published on 24 January 2020

Preferential activation of the 8-17 deoxyribozyme by Ca(2+) ions. Evidence for the identity of 8-17 with the catalytic domain of the Mg5 deoxyribozyme

scientific article published on 01 April 2000

Prospects for antiviral ribozymes and deoxyribozymes

scientific article published on January 2004

Recombinant production of eight human cytosolic aminotransferases and assessment of their potential involvement in glyoxylate metabolism.

scientific article published on 13 August 2009

Regulation of human serine racemase activity and dynamics by halides, ATP and malonate

article

Rescue of abasic hammerhead ribozymes by exogenous addition of specific bases

scientific article published on October 1996

Serine racemase: a key player in neuron activity and in neuropathologies

scientific article published on June 2013

Strict reaction and substrate specificity of AGXT2L1, the human O-phosphoethanolamine phospho-lyase

scientific article published on 12 June 2013

Structural characterization of human O-phosphoethanolamine phospho-lyase

scientific article published on 01 April 2020

Structure-function relationships in the hammerhead ribozyme probed by base rescue

scientific article published in November 1998

The B6 database: a tool for the description and classification of vitamin B6-dependent enzymatic activities and of the corresponding protein families

scientific article published in September 2009

The Limits of Enzyme Specificity and the Evolution of Metabolism

scientific article published on 25 October 2018

The Microbial Degradation of Natural and Anthropogenic Phosphonates

scientific article published in 2023

The advantages of being locked. Assessing the cleavage of short and long RNAs by locked nucleic acid-containing 8-17 deoxyribozymes

scientific article published in October 2007

Time-resolved fluorescence of tryptophan synthase

scientific article published in August 1996

Use of intrinsic binding energy for catalysis by an RNA enzyme

scientific article published on August 1997

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