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List of works by Ying-Yong Zhao

1β-hydroxylfriedelin, a new natural pentacylic triterpene from the sclerotia of <I>Polyporus umbellatus</I> ⬇️

scientific article published on 16 December 2009

A pharmaco-metabonomic study on chronic kidney disease and therapeutic effect of ergone by UPLC-QTOF/HDMS

scientific article published on 23 December 2014

A sensitive spectrofluorometric method for determination of ergosta-4,6,8(14),22-tetraen-3-one in rat plasma, feces, and urine for application to pharmacokinetic studies using cerium(III) as a probe.

scientific article published in January 2013

A simple and rapid spectrofluorimetric method for determining the pharmacokinetics and metabolism of rhaponticin in rat plasma, feces and urine using a cerium probe ⬇️

scientific article published on January 31, 2013

Activated NF-κB/Nrf2 and Wnt/β-catenin pathways are associated with lipid metabolism in CKD patients with microalbuminuria and macroalbuminuria

scientific article published on 16 May 2019

Advancing Pan-cancer Gene Expression Survial Analysis by Inclusion of Non-coding RNA

scientific article published on 18 October 2019

Aggregation-induced emission of 1,8-naphthalimide-casein micelle: investigation by synchronous spectrographic method

scientific article published in September 2013

Alisol B 23-acetate attenuates CKD progression by regulating the renin-angiotensin system and gut-kidney axis

scientific article published on 20 May 2020

Altered intestinal microbial flora and impaired epithelial barrier structure and function in CKD: the nature, mechanisms, consequences and potential treatment.

scientific article published on 16 April 2015

An Integrated Lipidomics and Phenotype Study Reveals Protective Effect and Biochemical Mechanism of Traditionally Used Alisma orientale Juzepzuk in Chronic Kidney Disease.

scientific article published on 8 February 2018

An expeditious HPLC method to distinguish Aconitum kusnezoffii from related species

scientific article published on 24 April 2009

An integrated lipidomics and metabolomics reveal nephroprotective effect and biochemical mechanism of Rheum officinale in chronic renal failure.

scientific article published on 23 February 2016

Application of faecal metabonomics on an experimental model of tubulointerstitial fibrosis by ultra performance liquid chromatography/high-sensitivity mass spectrometry with MS(E) data collection technique

scientific article

Architectures and accuracy of artificial neural network for disease classification from omics data

scientific article published on 04 March 2019

Aryl hydrocarbon receptor activation mediates kidney disease and renal cell carcinoma

scientific article published on 05 September 2019

Bioactivity-directed isolation, identification of diuretic compounds from Polyporus umbellatus.

scientific article published on 7 August 2009

Biomarkers of obstructive nephropathy using a metabolomics approach in rat

scientific article published on 17 October 2018

Cancer-specific expression quantitative loci are affected by expression dysregulation

scientific article published on 23 November 2018

Characterization of a Novel Polysaccharide-Iron(III) Complex and Its Anti-Anemia and Nonspecific Immune Regulating Activities

scientific article published on 24 April 2017

Characterization of the interaction between 4-(tetrahydro-2-furanmethoxy)-N-octadecyl-1,8-naphthalimide and human serum albumin by molecular spectroscopy and its analytical application

scientific article

Chemical composition and antioxidant activities of extracts from Apocyni Veneti Folium

scientific article published on 11 August 2011

Chronic kidney disease: Biomarker diagnosis to therapeutic targets

scientific article published on 30 August 2019

Cloud-point extraction combined with liquid chromatography for the determination of ergosterol, a natural product with diuretic activity, in rat plasma, urine, and faeces

scientific article published on 10 April 2013

Combined Clinical Phenotype and Lipidomic Analysis Reveals the Impact of Chronic Kidney Disease on Lipid Metabolism.

scientific article published on 13 March 2017

Combined melatonin and poricoic acid A inhibits renal fibrosis through modulating the interaction of Smad3 and β-catenin pathway in AKI-to-CKD continuum

scientific article published on 14 August 2019

Cytotoxicity of Fe3O4/Au composite nanoparticles loaded with doxorubicin combined with magnetic field.

scientific article published on July 2010

Dietary natural flavonoids treating cancer by targeting aryl hydrocarbon receptor

scientific article published on 01 May 2019

Diuretic activity of some fractions of the epidermis of Poria cocos

scientific article published on 30 October 2013

Diuretic activity of the ethanol and aqueous extracts of the surface layer of Poria cocos in rat

scientific article published on 08 October 2012

Diuretic and anti-diuretic activities of fractions of Alismatis rhizoma.

scientific article

Diuretic and anti-diuretic activities of the ethanol and aqueous extracts of Alismatis rhizoma.

scientific article published on 16 April 2014

Dose-dependent deleterious and salutary actions of the Nrf2 inducer dh404 in chronic kidney disease.

scientific article published on 27 April 2015

Effect of ergosta-4,6,8(14),22-tetraen-3-one (ergone) on adenine-induced chronic renal failure rat: a serum metabonomic study based on ultra performance liquid chromatography/high-sensitivity mass spectrometry coupled with MassLynx i-FIT algorithm.

scientific article

Enhanced Pharmacokinetics and Anti-Tumor Efficacy of PEGylated Liposomal Rhaponticin and Plasma Protein Binding Ability of Rhaponticin ⬇️

scientific article published on 01 October 2012

Enhanced distribution and anti-tumor activity of ergosta-4,6,8(14),22-tetraen-3-one by polyethylene glycol liposomalization

scientific article published on 01 February 2013

Ergosta-4,6,8(14),22-tetraen-3-one induces G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells ⬇️

scientific article published on January 15, 2011

Ergosta-4,6,8(14),22-tetraen-3-one isolated from Polyporus umbellatus prevents early renal injury in aristolochic acid-induced nephropathy rats

scientific article published on 10 October 2011

Folate-functionalized nanoparticles for controlled ergosta-4,6,8(14),22-tetraen-3-one delivery.

scientific article published on 20 December 2012

Gene and protein expressions and metabolomics exhibit activated redox signaling and wnt/β-catenin pathway are associated with metabolite dysfunction in patients with chronic kidney disease

scientific article published on 23 March 2017

Genomic Positional Dissection of RNA Editomes in Tumor and Normal Samples

scientific article published on 20 March 2019

Gut microbiota-derived tryptophan metabolism mediates renal fibrosis by aryl hydrocarbon receptor signaling activation

scientific article published on 23 September 2020

Identification of endogenous 1-aminopyrene as a novel mediator of progressive chronic kidney disease via aryl hydrocarbon receptor activation

scientific article published on 26 March 2020

Identification of five gelatins by ultra performance liquid chromatography/time-of-flight mass spectrometry (UPLC/Q-TOF-MS) using principal component analysis.

scientific article published on 29 December 2011

Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan

scientific article published on 01 April 2019

Intrarenal metabolomic investigation of chronic kidney disease and its TGF-β1 mechanism in induced-adenine rats using UPLC Q-TOF/HSMS/MS(E).

scientific article published on 10 January 2013

Lipidomics applications for discovering biomarkers of diseases in clinical chemistry

scientific article

Lipidomics applications for disease biomarker discovery in mammal models

scientific article

Lipidomics: Novel insight into the biochemical mechanism of lipid metabolism and dysregulation-associated disease.

scientific article published on 7 September 2015

Lipidomics: new insight into kidney disease.

scientific article published on 07 January 2015

Metabolomic Signatures of Chronic Kidney Disease of Diverse Etiologies in the Rats and Humans.

scientific article

Metabolomic application in toxicity evaluation and toxicological biomarker identification of natural product.

scientific article published on 31 March 2016

Metabolomics analysis reveals the association between lipid abnormalities and oxidative stress, inflammation, fibrosis, and Nrf2 dysfunction in aristolochic acid-induced nephropathy

scientific article published on 7 August 2015

Metabolomics highlights pharmacological bioactivity and biochemical mechanism of traditional Chinese medicine

scientific article

Metabolomics in chronic kidney disease ⬇️

scientific article published on 06 April 2013

Metabolomics in dyslipidemia.

scientific article

Metabolomics in nephrotoxicity.

scientific article

Metabolomics insights into activated redox signaling and lipid metabolism dysfunction in chronic kidney disease progression.

scientific article published on 28 September 2016

Metabolomics insights into chronic kidney disease and modulatory effect of rhubarb against tubulointerstitial fibrosis

scientific article

Microbiome-metabolome reveals the contribution of gut-kidney axis on kidney disease

Microbiome-metabolomics reveals gut microbiota associated with glycine-conjugated metabolites and polyamine metabolism in chronic kidney disease

scientific article published on 30 May 2019

Natural Products as a Source for Antifibrosis Therapy

scientific article published on 26 September 2018

Natural products for the prevention and treatment of kidney disease

scientific article published on 17 September 2018

New insights into TGF-β/Smad signaling in tissue fibrosis

scientific article published on 11 July 2018

Non-canonical RNA-DNA differences and other human genomic features are enriched within very short tandem repeats

scientific article published on 08 June 2020

Novel RAS inhibitor 25-O-methylalisol F attenuates epithelial-to-mesenchymal transition and tubulo-interstitial fibrosis by selectively inhibiting TGF-β-mediated Smad3 phosphorylation.

scientific article published on 19 March 2018

Novel RAS inhibitors poricoic acid ZG and poricoic acid ZH attenuate renal fibrosis via Wnt/β-catenin pathway and targeted phosphorylation smad3 signaling

scientific article published on 31 January 2018

Novel inhibitors of the cellular RAS components, Poricoic acids, target Smad3 phosphorylation and Wnt/β-catenin pathway against renal fibrosis

scientific article published on 21 April 2018

PEG-modified GoldMag nanoparticles (PGMNs) combined with the magnetic field for local drug delivery

scientific article published on 13 May 2010

Pharmacokinetics of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside in rat using ultra-performance LC-quadrupole TOF-MS.

scientific article published in February 2013

Pharmacokinetics of ergosterol in rats using rapid resolution liquid chromatography-atmospheric pressure chemical ionization multi-stage tandem mass spectrometry and rapid resolution liquid chromatography/tandem mass spectrometry

scientific article

Pharmacokinetics, bioavailability and metabolism of rhaponticin in rat plasma by UHPLC-Q-TOF/MS and UHPLC-DAD-MSn

scientific article published on 01 March 2012

Plasma lipidomics reveal profound perturbation of glycerophospholipids, fatty acids, and sphingolipids in diet-induced hyperlipidemia.

scientific article published on 22 January 2015

Poricoic acid A as a modulator of TPH-1 expression inhibits renal fibrosis via modulating protein stability of β-catenin and β-catenin-mediated transcription

scientific article published on 30 September 2020

Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis

scientific article published on 02 February 2019

Poricoic acid ZA, a novel RAS inhibitor, attenuates tubulo-interstitial fibrosis and podocyte injury by inhibiting TGF-β/Smad signaling pathway

scientific article published on 12 October 2017

Power and sample size calculations for high-throughput sequencing-based experiments.

scientific article published on 09 June 2017

Preparation and characterization of D. opposita Thunb polysaccharide-zinc inclusion complex and evaluation of anti-diabetic activities

scientific article published on 17 October 2018

Proteomics for Biomarker Identification and Clinical Application in Kidney Disease.

scientific article published on 6 March 2018

Quality and concordance of genotyping array data of 12,064 samples from 5840 cancer patients

scientific article published on 11 June 2018

Quality control of natural product medicine and nutrient supplements

scientific article published on 16 July 2013

Quality control of natural product medicine and nutrient supplements 2014

scientific article

Quantitative HPLC method and pharmacokinetic studies of ergosta-4,6,8(14),22-tetraen-3-one, a natural product with diuretic activity from Polyporus umbellatus.

scientific article

Rapid resolution liquid chromatography-mass spectrometry and high-performance liquid chromatography-fluorescence detection for metabolism and pharmacokinetic studies of ergosta-4,6,8(14),22-tetraen-3-one

scientific article

Recognition of Bisecting N-Glycans on Intact Glycopeptides by Two Characteristic Ions in Tandem Mass Spectra

scientific article published on 22 April 2019

Redox signaling and Alzheimer's disease: from pathomechanism insights to biomarker discovery and therapy strategy

scientific article published on 11 September 2020

Redox signaling in aging kidney and opportunity for therapeutic intervention through natural products

scientific article published on 11 June 2019

Removal of uremic retention products by hemodialysis is coupled with indiscriminate loss of vital metabolites

scientific article published on 16 September 2017

Renal metabolic profiling of early renal injury and renoprotective effects of Poria cocos epidermis using UPLC Q-TOF/HSMS/MSE ⬇️

scientific article published on April 16, 2013

Research Progress of Natural Product Gentiopicroside - a Secoiridoid Compound

scientific article published on 24 June 2016

Rhubarb Protect Against Tubulointerstitial Fibrosis by Inhibiting TGF-β/Smad Pathway and Improving Abnormal Metabolome in Chronic Kidney Disease

scholarly article by Zhi-Hao Zhang et al published 2018 in Frontiers in Pharmacology

Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy.

scientific article

Serum metabonomics study of adenine-induced chronic renal failure in rats by ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry

scientific article

Simultaneous determination of eight major steroids from Polyporus umbellatus by high-performance liquid chromatography coupled with mass spectrometry detections

scientific article

Single-nucleotide variants in human RNA: RNA editing and beyond

scientific article published on 01 February 2019

Small molecule inhibitors of epithelial-mesenchymal transition for the treatment of cancer and fibrosis

scientific article published on 27 May 2019

Solvent effect on the absorption and fluorescence of ergone: determination of ground and excited state dipole moments

scientific article published on 14 October 2011

Solvent effects on the absorption and fluorescence spectra of rhaponticin: experimental and theoretical studies.

scientific article published on 23 October 2012

Synthesis and biological evaluation of a folate-targeted rhaponticin conjugate.

scientific article published on 3 November 2012

Synthesis and spectroscopic characterization of 4-butoxyethoxy-N-octadecyl-1,8-naphthalimide as a new fluorescent probe for the determination of proteins ⬇️

scientific article published on April 19, 2011

The Landscape of Small Non-Coding RNAs in Triple-Negative Breast Cancer

scientific article published on 10 January 2018

The Matrix Metalloproteinase-13 Inhibitor Poricoic Acid ZI Ameliorates Renal Fibrosis by Mitigating Epithelial-Mesenchymal Transition

scientific article published on 29 March 2019

The link between phenotype and fatty acid metabolism in advanced chronic kidney disease.

scientific article published in March 2017

The proliferation, differentiation, and mineralization effects of puerarin on osteoblasts in vitro

scientific article published on 01 June 2014

Traditional uses, fermentation, phytochemistry and pharmacology of Phellinus linteus: A review.

scientific article

Traditional uses, phytochemistry, pharmacology, pharmacokinetics and quality control of Polyporus umbellatus (Pers.) Fries: A review ⬇️

scientific article published on June 26, 2013

Traditional uses, phytochemistry, pharmacology, toxicology and quality control of Alisma orientale (Sam.) Juzep: a review.

scientific article

UPLC-MS(E) application in disease biomarker discovery: the discoveries in proteomics to metabolomics

scientific article published on 12 March 2014

UPLC-Q-TOF/HSMS/MSE-based metabonomics for adenine-induced changes in metabolic profiles of rat faeces and intervention effects of ergosta-4,6,8(14),22-tetraen-3-one ⬇️

scientific article published on December 13, 2012

UPLC-based metabonomic applications for discovering biomarkers of diseases in clinical chemistry

scientific article

Ultra performance liquid chromatography coupled with electrospray and atmospheric pressure chemical ionization (ESCi)-quadrupole time-of-flight mass spectrometry with novel mass spectrometry(Elevated Energy) (MS(E)) data collection technique: determ

scientific article

Ultra performance liquid chromatography-based metabonomic study of therapeutic effect of the surface layer of Poria cocos on adenine-induced chronic kidney disease provides new insight into anti-fibrosis mechanism

scientific article

Ultra-performance liquid chromatography-mass spectrometry as a sensitive and powerful technology in lipidomic applications

scientific article published on 09 July 2014

Unilateral ureteral obstruction causes gut microbial dysbiosis and metabolome disorders contributing to tubulointerstitial fibrosis

scientific article published on 27 March 2019

Urinary biomarker and treatment mechanism of Rhizoma Alismatis on hyperlipidemia.

scientific article

Urinary metabolomics and biomarkers of aristolochic acid nephrotoxicity by UPLC-QTOF/HDMS.

scientific article published on April 2015

Urinary metabonomic study of the surface layer of Poria cocos as an effective treatment for chronic renal injury in rats.

scientific article

Urinary metabonomics study on biochemical changes in an experimental model of chronic renal failure by adenine based on UPLC Q-TOF/MS

scientific article published on 24 December 2011

Using the Doubly Charged Selected Ion Coupled with MS/MS Fragments Monitoring (DCSI-MS/MS) Mode for the Identification of Gelatin Species

scientific article published on 13 March 2014

[Chemical constituents of surface layer of Poria cocos and their pharmacological properties (I)]

article published in 2013

[Research progress on pharmacology, pharmacokinetics and determination of ergosta-4,6,8 (14),22-tetraen-3-one]

scholarly article by Han Chen et al published 1 October 2014 in Zhongguo Zhongyao Zazhi

[Studies on HPLC fingerprint of Radix Aconiti Kusnezoffii]

scientific article published on 01 July 2006

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