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List of works by Xu-Dong Kong

A smart library of epoxide hydrolase variants and the top hits for synthesis of (S)-β-blocker precursors.

scientific article

Bypassing bacterial infection in phage display by sequencing DNA released from phage particles

scientific article

Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition

scientific article

Cyclic peptide FXII inhibitor provides safe anticoagulation in a thrombosis model and in artificial lungs

scientific article published on 04 August 2020

Cyclization of peptides with two chemical bridges affords large scaffold diversities

scientific article published on 30 April 2018

De novo development of proteolytically resistant therapeutic peptides for oral administration

scientific article published on 11 May 2020

Engineering Streptomyces coelicolor Carbonyl Reductase for Efficient Atorvastatin Precursor Synthesis.

scientific article published on 07 April 2017

Engineering of an epoxide hydrolase for efficient bioresolution of bulky pharmaco substrates

scientific article

Heterologous overexpression of Vigna radiata epoxide hydrolase in Escherichia coli and its catalytic performance in enantioconvergent hydrolysis of p-nitrostyrene oxide into (R)-p-nitrophenyl glycol ⬇️

scientific article published on April 25, 2013

Phage Selection of Cyclic Peptides for Application in Research and Drug Development.

scientific article published on 18 July 2017

Protein engineering of aldolase LbDERA for enhanced activity toward real substrates with a high-throughput screening method coupled with an aldehyde dehydrogenase.

scientific article

Reshaping an enzyme binding pocket for enhanced and inverted stereoselectivity: use of smallest amino acid alphabets in directed evolution

scientific article

Structural and Computational Insight into the Catalytic Mechanism of Limonene Epoxide Hydrolase Mutants in Stereoselective Transformations.

scientific article published on 12 December 2017

Switching a newly discovered lactonase into an efficient and thermostable phosphotriesterase by simple double mutations His250Ile/Ile263Trp

scientific article

Thiol-to-amine cyclization reaction enables screening of large libraries of macrocyclic compounds and the generation of sub-kilodalton ligands

scientific article published on 21 August 2019

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