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List of works by Gianfranco Caselli

An HGF-MSP chimera disassociates the trophic properties of scatter factors from their pro-invasive activity.

scientific article

Analgesic efficacy of CR4056, a novel imidazoline-2 receptor ligand, in rat models of inflammatory and neuropathic pain

scientific article

Andolast acts at different cellular levels to inhibit immunoglobulin E synthesis.

scientific article published in January 2009

Antihistaminic/antiallergic activity of 2-dialkylaminoalkylthio(oxy)-1-substituted benzimidazoles: evaluation "in vitro" and "in vivo".

scientific article published in April 1990

CR13626: a novel oral brain penetrant tyrosine kinase inhibitor that reduces tumor growth and prolongs survival in a mouse model of glioblastoma

scientific article published on 15 July 2021

CR4056, a new analgesic I2 ligand, is highly effective against bortezomib-induced painful neuropathy in rats.

scientific article

CR4056, a powerful analgesic imidazoline-2 receptor ligand, inhibits the inflammation-induced PKCε phosphorylation and membrane translocation in sensory neurons

scientific article published on 07 November 2019

Dendrimeric tetravalent ligands for the serotonin-gated ion channel

scientific article published on 23 June 2014

Design, synthesis, and biological evaluation of AT1 angiotensin II receptor antagonists based on the pyrazolo[3,4-b]pyridine and related heteroaromatic bicyclic systems.

scientific article published on 5 March 2008

Design, synthesis, and preliminary biological evaluation of pyrrolo[3,4-c]quinolin-1-one and oxoisoindoline derivatives as aggrecanase inhibitors.

scientific article published in May 2010

Does colchicine really induce bone formation in the rodent bone Marrow? Yes, it does

scientific article published on 01 November 1999

EFFICACY OF A NEW TOPICAL GEL-SPRAY FORMULATION OF KETOPROFEN LYSINE SALT IN THE RAT: PERCUTANEOUS PERMEATIONIN VITROANDIN VIVOAND PHARMACOLOGICAL ACTIVITY

scientific article published on 01 January 1998

Effectiveness of carbocysteine lysine salt monohydrate on models of airway inflammation and hyperresponsiveness.

scientific article published in June 1995

Efficacy of CR4056, a first-in-class imidazoline-2 analgesic drug, in comparison with naproxen in two rat models of osteoarthritis.

scientific article

Experimental pharmacology of glucosamine sulfate.

scientific article published on 09 October 2011

Exploring multitarget interactions to reduce opiate withdrawal syndrome and psychiatric comorbidity

scientific article

Functional in vitro characterization of CR 3394: a novel voltage dependent N-methyl-D-aspartate (NMDA) receptor antagonist.

scientific article published on 19 October 2005

IL-1 beta primes IL-8-activated human neutrophils for elastase release, phospholipase D activity, and calcium flux

scientific article published on 01 March 1996

IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease

scientific article

Improved efficacy, tolerance, safety and abuse liability profile of the combination CR4056-morphine over morphine alone in rodent models

scientific article published on 10 March 2020

Lipopolysaccharide-induced lung injury in mice. I. Concomitant evaluation of inflammatory cells and haemorrhagic lung damage

scientific article published on 01 January 2000

Lipopolysaccharide-induced lung injury in mice. II. Evaluation of functional damage in isolated parenchyma strips

scientific article published on 01 January 2000

Lps induces IL-6 in the brain and in serum largely through TNF production

scientific article published on 01 August 2000

Modulation of imidazoline I2 binding sites by CR4056 relieves postoperative hyperalgesia in male and female rats

scientific article

Multivalent ligands for the serotonin 5-HT receptor

scientific article published on 09 February 2017

Multivalent supramolecular dendrimer-based drugs

scientific article

Peripheral blood mononuclear cell production of interleukin-8 and IL-8-dependent neutrophil function in hypercholesterolemic patients

scientific article published on 01 October 1999

Pharmacokinetic study of a new angiotensin-AT1 antagonist by HPLC

scientific article published on 30 March 2008

Pharmacological characterisation of CR6086, a potent prostaglandin E2 receptor 4 antagonist, as a new potential disease-modifying anti-rheumatic drug.

scientific article published in March 2018

Pharmacological profile of CR3465, a new leukotriene CysLT1 receptor antagonist with broad anti-inflammatory activity.

scientific article published in November 2004

Phenylindenone isomers as divergent modulators of p38α MAP kinase

scientific article published on 4 October 2016

Progress towards the identification of new aggrecanase inhibitors

scientific article published on January 2009

Prostaglandins and lipolysis I: PGI2 formation by rat epididymal adipose tissue artery

scientific article published on 01 September 1981

Role of tumor necrosis factor-alpha in endotoxin-induced lung parenchymal hyporesponsiveness in mice

scientific article published on 01 October 2001

Selective inhibition of interleukin-8-induced neutrophil chemotaxis by ketoprofen isomers.

scientific article published in June 2001

Supramolecular glycodendrimer-based hybrid drugs

scientific article published on 20 October 2014

Synthesis and in vitro and in vivo evaluation of the 2-(6'methoxy-3',4'-dihydro-1'-naphtyl)-4H-3,1-benzoxazin-4- one as a new potent substrate inhibitor of human leukocyte elastase

scientific article published on 01 May 1999

Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds

scientific article published on 8 February 2013

Synthesis and structure-activity relationship studies in serotonin 5-HT4 receptor ligands based on a benzo[de][2,6]naphthridine scaffold.

scientific article

Synthesis, inhibitory activity towards human leukocyte elastase and molecular modelling studies of 1-carbamoyl-4-methyleneaminoxyazetidinones

scientific article published on 01 January 2000

Synthesis, pharmacophore modeling and in vitro activity of 10,11-dihydrodibenzo[b,f]oxepine-4-carboxamide derivatives as novel and potent antagonists of the prostaglandin EP4 receptor

scientific article published on 01 September 2011

Tartronates: a new generation of drugs affecting bone metabolism

scientific article published on 01 June 1997

The novel anti-inflammatory agent VA694, endowed with both NO-releasing and COX2-selective inhibiting properties, exhibits NO-mediated positive effects on blood pressure, coronary flow and endothelium in an experimental model of hypertension and end

scientific article

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