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List of works by Clare M. Lloyd

A T cell-myeloid IL-10 axis regulates pathogenic IFN-γ-dependent immunity in a mouse model of type 2-low asthma

scientific article published on 22 August 2019

A critical role for IRF5 in regulating allergic airway inflammation.

scientific article published on 19 October 2016

A limited CpG-containing oligodeoxynucleotide therapy regimen induces sustained suppression of allergic airway inflammation in mice.

scientific article

Abnormal pro-gly-pro pathway and airway neutrophilia in pediatric cystic fibrosis

scientific article published on 05 June 2019

Activin A and TGF-β promote T(H)9 cell-mediated pulmonary allergic pathology.

scientific article

Activin-A induces regulatory T cells that suppress T helper cell immune responses and protect from allergic airway disease.

scientific article published on 20 July 2009

Adenoid-derived TH2 cells reactive to allergen and recall antigen express CC chemokine receptor 4.

scientific article

After asthma: redefining airways diseases.

scientific article published on 11 September 2017

Airway macrophages as the guardians of tissue repair in the lung

scientific article published on 15 February 2019

Allergen-induced airway remodelling

scientific article

Altered regulation of Toll-like receptor responses impairs antibacterial immunity in the allergic lung

scientific article

Alternaria-derived serine protease activity drives IL-33-mediated asthma exacerbations

scientific article

Alveolar macrophages are sentinels of murine pulmonary homeostasis following inhaled antigen challenge

scientific article

Amelioration of ovalbumin-induced allergic airway disease following Der p 1 peptide immunotherapy is not associated with induction of IL-35.

scientific article published on 14 August 2013

An NLRP3, IL-1β, Neutrophil Axis in the Respiratory Tract Leaves You Breathless

scientific article published in August 2017

An extracellular matrix fragment drives epithelial remodeling and airway hyperresponsiveness.

scientific article published in August 2018

Angiotensin-converting enzyme defines matrikine-regulated inflammation and fibrosis.

scientific article

Animal Models to Study Chemokine Receptor Function: In Vivo Mouse Models of Allergic Airway Inflammation

scientific article published on 01 January 2004

Asthma and allergy: the emerging epithelium

scientific article

Asthma: T-bet--a master controller?

scientific article published on April 2002

Bacterial burden in the lower airways predicts disease progression in idiopathic pulmonary fibrosis and is independent of radiological disease extent

scientific article published on 03 April 2020

CC Chemokine Ligand 1 Promotes Recruitment of Eosinophils But Not Th2 Cells During the Development of Allergic Airways Disease ⬇️

scientific article published on May 1, 2003

CC chemokine receptor 4 (CCR4) in human allergen-induced late nasal responses.

scientific article

CXCR1+CD4+ T cells in human allergic disease.

scientific article published in January 2004

CXCR2 mediates the recruitment of endothelial progenitor cells during allergic airways remodeling.

scientific article

Cell-matrix interactions in lung disease and regeneration: ERS Lung Science Conference 2018 report

scientific article published on 27 June 2018

Chair's summary: Innate and adaptive immune responses in airway disease

scientific article

Chemokine receptors : therapeutic potential in asthma

scientific article

Chemokines in allergic airway disease.

scientific article

Chemokines in allergic lung inflammation.

scientific article

Chronic inflammation and asthma

scientific article

Comparative primary paediatric nasal epithelial cell culture differentiation and RSV-induced cytopathogenesis following culture in two commercial media

scientific article published on 26 March 2020

Crucial role of the interleukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses. ⬇️

scientific article published on October 1999

Development of allergic immunity in early life.

scientific article published on July 2017

Developments in the field of allergy in 2009 through the eyes of Clinical and Experimental Allergy

scientific article

Dynamics of human monocytes and airway macrophages during healthy aging and after transplant

scientific article published on 01 March 2020

Early life inter-kingdom interactions shape the immunological environment of the airways

scientific article published on 21 February 2022

Early origins of lung disease: towards an interdisciplinary approach

scientific article published on 01 September 2020

Effects of steroid treatment on lung CC chemokines, apoptosis and transepithelial cell clearance during development and resolution of allergic airway inflammation.

scientific article published on January 2006

Elevated CCR6+ CD4+ T lymphocytes in tissue compared with blood and induction of CCL20 during the asthmatic late response.

scientific article published on 16 April 2008

Endothelin-1 directs airway remodeling and hyper-reactivity in a murine asthma model.

scientific article published on 14 October 2013

Enhanced frequency and function of follicular T cells in the tonsils of house dust mite-sensitized children

scientific article published on 14 December 2019

Eosinophils in the pathogenesis of allergic airways disease.

scientific article

Eosinophils in the pathogenesis of paediatric severe asthma

scientific article published on April 2014

Eosinophils in the spotlight: Finding the link between obesity and asthma.

scientific article published in August 2013

Eotaxin: from an eosinophilic chemokine to a major regulator of allergic reactions.

scientific article

Epigenetic Control of Interleukin-9 in Asthma

scientific article published on 01 July 2018

Epithelial cytokines and pulmonary allergic inflammation

scientific article

Epithelial-derived TGF-β1 acts as a pro-viral factor in the lung during influenza A infection.

scientific article

Functions of T cells in asthma: more than just T(H)2 cells.

scientific article

Group 2 ILC Functional Assays in Allergic Airway Inflammation

scientific article published on 01 January 2020

High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation

scientific article published on 16 December 2019

IL-33 family members and asthma - bridging innate and adaptive immune responses.

scientific article

IL-33 promotes airway remodeling in pediatric patients with severe steroid-resistant asthma

scientific article

IL-9 governs allergen-induced mast cell numbers in the lung and chronic remodeling of the airways

scientific article

Immuno-proteomic profiling reveals aberrant immune cell regulation in the airways of individuals with ongoing post-COVID-19 respiratory disease

scientific article published on 26 January 2022

Impaired airway epithelial cell wound-healing capacity is associated with airway remodelling following RSV infection in severe preschool wheeze

scientific article published on 23 June 2020

Inception of early-life allergen-induced airway hyperresponsiveness is reliant on IL-13+CD4+ T cells

scientific article published on 01 September 2018

Innate responsiveness of CD8 memory T-cell populations nonspecifically inhibits allergic sensitization

scientific article

Intraepithelial neutrophils in pediatric severe asthma are associated with better lung function

scientific article

Itaconate controls the severity of pulmonary fibrosis

scientific article published on 01 October 2020

Location, Location, Location: Localized Memory Cells Take Residence in the Allergic Lung.

scientific article published in January 2016

Lower airway microbiota associates with inflammatory phenotype in severe preschool wheeze

scientific article published on 21 December 2018

Lung Alveolar Repair: Not All Cells Are Equal

scientific article published in September 2017

Lung Homeostasis: Influence of Age, Microbes, and the Immune System

scientific article

Lung macrophages contribute to house dust mite driven airway remodeling via HIF-1α

scientific article (publication date: 2013)

Lung microbiota promotes tolerance to allergens in neonates via PD-L1.

scientific article

Manipulation of Dipeptidylpeptidase 10 in mouse and human in vivo and in vitro models indicates a protective role in asthma

scientific article published on 28 December 2017

Matrikines are key regulators in modulating the amplitude of lung inflammation in acute pulmonary infection.

scientific article

Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation

scientific article

Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation

scientific article (publication date: 5 June 1997)

Neutrophils drive alveolar macrophage IL-1β release during respiratory viral infection.

scientific article published on 27 October 2017

Neutrophils restrain allergic airway inflammation by limiting ILC2 function and monocyte-dendritic cell antigen presentation

scientific article published on 01 November 2019

Nonredundant role of CCRL2 in lung dendritic cell trafficking

scientific article

Novel concepts in airway inflammation and remodelling in asthma

scientific article

Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ.

scientific article

Of flies, mice and men: a systematic approach to understanding the early life origins of chronic lung disease

scientific article published on 10 July 2012

Opening the Window of Immune Opportunity: Treating Childhood Asthma

scientific article published on 14 August 2019

Orchestrating house dust mite-associated allergy in the lung.

scientific article

Osteopontin has a crucial role in allergic airway disease through regulation of dendritic cell subsets

scientific article

Pathophysiological features of asthma develop in parallel in house dust mite-exposed neonatal mice

scientific article

Pediatric severe asthma is characterized by eosinophilia and remodeling without T(H)2 cytokines

scientific article

Pediatric severe asthma with fungal sensitization is mediated by steroid-resistant IL-33

scientific article

Peptide immunotherapy in allergic asthma generates IL-10-dependent immunological tolerance associated with linked epitope suppression

scientific article published on 15 June 2009

Pericytes contribute to airway remodeling in a mouse model of chronic allergic asthma

scientific article

Perinatal paracetamol exposure in mice does not affect the development of allergic airways disease in early life

scientific article published on 3 April 2015

Phosphatidylethanolamine-esterified eicosanoids in the mouse: tissue localization and inflammation-dependent formation in Th-2 disease

scientific article published on 15 June 2009

Prolonged Eosinophil Accumulation in Allergic Lung Interstitium of ICAM-2-Deficient Mice Results in Extended Hyperresponsiveness

article

Prolonged allergen challenge in mice leads to persistent airway remodelling.

scientific article

Prostacyclin as a Potential Novel Means to Manipulate Type 2 Innate Lymphoid Cell Function.

scientific article

Pulmonary Epithelial Cell-Derived Cytokine TGF-β1 Is a Critical Cofactor for Enhanced Innate Lymphoid Cell Function

scientific article

Pulmonary Group 2 Innate Lymphoid Cell Phenotype Is Context Specific: Determining the Effect of Strain, Location, and Stimuli

scientific article published on 01 January 2019

Pulmonary Macrophages: A New Therapeutic Pathway in Fibrosing Lung Disease?

scientific article published on 12 March 2016

Pulmonary ORMDL3 is critical for induction of Alternaria-induced allergic airways disease.

scientific article

Pulmonary environmental cues drive group 2 innate lymphoid cell dynamics in mice and humans

scientific article published on 01 June 2019

Pulmonary epithelial barrier and immunological functions at birth and in early life - key determinants of the development of asthma? A description of the protocol for the Breathing Together study

article

Pulmonary macrophages: key players in the innate defence of the airways.

scientific article published on 18 August 2015

Pulmonary type-2 innate lymphoid cells in paediatric severe asthma: phenotype and response to steroids

scientific article published on 29 August 2019

RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis

scientific article

Recurrent Severe Preschool Wheeze: From Prespecified Diagnostic Labels to Underlying Endotypes

scientific article published on 01 September 2021

Regulation of ectodomain shedding of ADAM33 in vitro and in vivo.

scientific article published on 2 February 2019

Regulatory T cells in asthma

scientific article

Regulatory cytokine function in the respiratory tract

scientific article published on 15 March 2019

Reply

article published in 2017

Resolution of airway inflammation and hyperreactivity after in vivo transfer of CD4+CD25+ regulatory T cells is interleukin 10 dependent.

scientific article

Resolution of allergic airway inflammation and airway hyperreactivity is mediated by IL-17-producing {gamma}{delta}T cells

scientific article

Resolution of allergic inflammation and airway hyperreactivity is dependent upon disruption of the T1/ST2-IL-33 pathway

scientific article published on 29 January 2009

Respiratory microbiome and epithelial interactions shape immunity in the lungs

scientific article published on 20 March 2020

Respiratory syncytial virus infection provokes airway remodelling in allergen-exposed mice in absence of prior allergen sensitization.

scientific article

Response to Comment on "An extracellular matrix fragment drives epithelial remodeling and airway hyperresponsiveness"

scientific article published on 01 June 2019

Reversal of TREM-1 ectodomain shedding and improved bacterial clearance by intranasal metalloproteinase inhibitors

scientific article published on 14 December 2016

Role of MCP-1 and RANTES in inflammation and progression to fibrosis during murine crescentic nephritis ⬇️

scientific article published on 01 November 1997

Screening-based discovery and structural dissection of a novel family 18 chitinase inhibitor

scientific article published on 14 July 2006

Special delivery: how macrophages get the message across

scientific article published on May 2015

Suppression of allergic airway inflammation and IgE responses by a class I restricted allergen peptide vaccine. ⬇️

scientific article

T cells in asthma: Influences of genetics, environment, and T-cell plasticity ⬇️

scientific article published on March 28, 2013

T lymphocytes expressing CCR3 are increased in allergic rhinitis compared with non-allergic controls and following allergen immunotherapy

scientific article

Targeting the ICOS/ICOS-L pathway in a mouse model of established allergic asthma disrupts T follicular helper cell responses and ameliorates disease

article

Tasting type 2 inflammation in the airways

scientific article published on 19 June 2018

Th17 responses in chronic allergic airway inflammation abrogate regulatory T-cell-mediated tolerance and contribute to airway remodeling ⬇️

scientific article published on August 15, 2012

The Coordinated Action of CC Chemokines in the Lung Orchestrates Allergic Inflammation and Airway Hyperresponsiveness ⬇️

scientific article published on July 6, 1998

The Th17 pathway in cystic fibrosis lung disease.

scientific article

The Transferrin Receptor CD71 Delineates Functionally Distinct Airway Macrophage Subsets during Idiopathic Pulmonary Fibrosis

scientific article published on 01 July 2019

The absence of interleukin 9 does not affect the development of allergen-induced pulmonary inflammation nor airway hyperreactivity.

scientific article published on January 2002

The chemotactic cytokine eotaxin acts as a granulocyte-macrophage colony-stimulating factor during lung inflammation ⬇️

scientific article published on March 15, 1998

The development of novel LTA4H modulators to selectively target LTB4 generation.

scientific article published on 17 March 2017

The enigmatic role of the neutrophil in asthma: Friend, foe or indifferent?

scientific article published on 11 July 2018

The role of chemokines in tissue inflammation and autoimmunity in renal diseases ⬇️

scientific article published on May 1, 1998

Therapeutic ICOS blockade reduces T follicular helper cells and improves allergic airway disease

Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases

scientific article published on 28 June 2019

Transcriptomic analysis reveals diverse gene expression changes in airway macrophages during experimental allergic airway disease

scientific article published on 26 May 2020

Type 2 immunity: Expanding our view

scientific article published on 01 July 2018

Type 2 innate lymphoid cells in induced sputum from children with severe asthma

scientific article published on 12 August 2015

Vitamin D deficiency induces Th2 skewing and eosinophilia in neonatal allergic airways disease

scientific article

Year in review 2013: basic science and epidemiology

scientific article published on 28 March 2014

γδT cells regulate chronic airway inflammation and development of airway remodelling.

scientific article

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