List of works - Marta Valenza

A gene network regulating lysosomal biogenesis and function

scientific article

An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin

scientific article published in May 2012

Analysis of the repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy of non-neuronal genes in peripheral lymphocytes from patients with Huntington's disease

scientific article published on 23 December 2008

Brain-derived neurotrophic factor in patients with Huntington's disease

scientific article

Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation.

scientific article

Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes

scientific article

Cholesterol dysfunction in neurodegenerative diseases: is Huntington's disease in the list?

scientific article published on 25 October 2006

Cholesterol-loaded nanoparticles ameliorate synaptic and cognitive function in Huntington's disease mice

scientific article published on 20 November 2015

Disruption of astrocyte-neuron cholesterol cross talk affects neuronal function in Huntington's disease.

scientific article

Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease.

scientific article published in October 2005

Early and brain region-specific decrease of de novo cholesterol biosynthesis in Huntington's disease: A cross-validation study in Q175 knock-in mice

scientific article published on 29 November 2016

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses

scientific article published in August 2002

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses

scientific article published on 21 November 2014

Emerging roles for cholesterol in Huntington's disease ⬇️

scientific article published on July 19, 2011

Evaluation of histone deacetylases as drug targets in Huntington's disease models. Study of HDACs in brain tissues from R6/2 and CAG140 knock-in HD mouse models and human patients and in a neuronal HD cell model

scientific article

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

scientific article (publication date: September 2003)

In vitro and in vivo models of Huntington's disease show alterations in the endocannabinoid system

scientific journal article

Lack of huntingtin promotes neural stem cells differentiation into glial cells while neurons expressing huntingtin with expanded polyglutamine tracts undergo cell death

scientific article

Loss of huntingtin function complemented by small molecules acting as repressor element 1/neuron restrictive silencer element silencer modulators

scientific article

Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease ⬇️

scientific article published on July 1, 2010

Neuroprotection and brain cholesterol biosynthesis in Huntington's disease

scientific article published on 31 August 2010

Peroxisome-proliferator-activated receptor gamma coactivator 1 α contributes to dysmyelination in experimental models of Huntington's disease

scientific article published on June 2011

Pitfalls in the detection of cholesterol in Huntington's disease models

scientific article

Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease.

scientific article published on 4 September 2008

Prevention of cytosolic IAPs degradation: a potential pharmacological target in Huntington's Disease

scientific article published on August 2005

Progressive dysfunction of the cholesterol biosynthesis pathway in the R6/2 mouse model of Huntington's disease.

scientific article

Progressive loss of BDNF in a mouse model of Huntington's disease and rescue by BDNF delivery

scientific article published in August 2005

Striatal infusion of cholesterol promotes dose-dependent behavioral benefits and exerts disease-modifying effects in Huntington's disease mice

scientific article published on 22 September 2020

Whole body cholesterol metabolism is impaired in Huntington's disease.

scientific article published on 22 March 2011

List of works by Marta Valenza

A gene network regulating lysosomal biogenesis and function

An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin

Analysis of the repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy of non-neuronal genes in peripheral lymphocytes from patients with Huntington's disease

Brain-derived neurotrophic factor in patients with Huntington's disease

Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation.

Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes

Cholesterol dysfunction in neurodegenerative diseases: is Huntington's disease in the list?

Cholesterol-loaded nanoparticles ameliorate synaptic and cognitive function in Huntington's disease mice

Disruption of astrocyte-neuron cholesterol cross talk affects neuronal function in Huntington's disease.

Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease.

Early and brain region-specific decrease of de novo cholesterol biosynthesis in Huntington's disease: A cross-validation study in Q175 knock-in mice

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses

Emerging roles for cholesterol in Huntington's disease ⬇️

Evaluation of histone deacetylases as drug targets in Huntington's disease models. Study of HDACs in brain tissues from R6/2 and CAG140 knock-in HD mouse models and human patients and in a neuronal HD cell model

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

In vitro and in vivo models of Huntington's disease show alterations in the endocannabinoid system

Lack of huntingtin promotes neural stem cells differentiation into glial cells while neurons expressing huntingtin with expanded polyglutamine tracts undergo cell death

Loss of huntingtin function complemented by small molecules acting as repressor element 1/neuron restrictive silencer element silencer modulators

Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease ⬇️

Neuroprotection and brain cholesterol biosynthesis in Huntington's disease

Peroxisome-proliferator-activated receptor gamma coactivator 1 α contributes to dysmyelination in experimental models of Huntington's disease

Pitfalls in the detection of cholesterol in Huntington's disease models

Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease.

Prevention of cytosolic IAPs degradation: a potential pharmacological target in Huntington's Disease

Progressive dysfunction of the cholesterol biosynthesis pathway in the R6/2 mouse model of Huntington's disease.

Progressive loss of BDNF in a mouse model of Huntington's disease and rescue by BDNF delivery

Striatal infusion of cholesterol promotes dose-dependent behavioral benefits and exerts disease-modifying effects in Huntington's disease mice

Whole body cholesterol metabolism is impaired in Huntington's disease.