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List of works by Merlin Thomas

A Prospective, Multicenter Study of Pharmacist Activities Resulting in Medication Error Interception in the Emergency Department ⬇️

scientific article published on 05 January 2012

A Review of the External Validity of Clinical Trials with Beta-Blockers in Heart Failure

scientific article

A developmental nephron deficit in rats is associated with increased susceptibility to a secondary renal injury due to advanced glycation end-products.

scientific article published on 23 February 2006

A physician-initiated double-blind, randomised, placebo-controlled, phase 2 study evaluating the efficacy and safety of inhibition of NADPH oxidase with the first-in-class Nox-1/4 inhibitor, GKT137831, in adults with type 1 diabetes and persistently

scientific article published on 16 November 2019

A preliminary evaluation of bardoxolone methyl for the treatment of diabetic nephropathy

scientific article published on 30 June 2012

ACE2 deficiency shifts energy metabolism towards glucose utilization

scientific article published on 20 November 2014

Accelerated nephropathy in diabetic apolipoprotein e-knockout mouse: role of advanced glycation end products.

scientific article

Added value of soluble tumor necrosis factor-α receptor 1 as a biomarker of ESRD risk in patients with type 1 diabetes

scientific article published on 30 May 2014

Advanced glycation end product interventions reduce diabetes-accelerated atherosclerosis.

scientific article

Advanced glycation end products and diabetic nephropathy.

scientific article

Advanced glycation end products.

scientific article published on 09 June 2011

Advanced glycation of apolipoprotein A-I impairs its anti-atherogenic properties.

scientific article

Advanced glycation: how are we progressing to combat this web of sugar anomalies in diabetic nephropathy

scientific article

An acute fall in estimated glomerular filtration rate during treatment with losartan predicts a slower decrease in long-term renal function

scientific article published on 30 March 2011

An outbreak of leptospirosis on a single farm in east Otago

scientific article published on 01 July 1994

Anaemia in diabetes: Is there a rationale to TREAT?

scientific article

Anemia in patients with type 1 diabetes

scientific article published on 01 September 2004

Anemia with impaired erythropoietin response in diabetic patients

scientific article published on 01 February 2005

Angiotensin II and its role in tubular epithelial to mesenchymal transition associated with chronic kidney disease

scientific article published on November 2, 2010

Angiotensin II mediates epithelial-to-mesenchymal transformation in tubular cells by ANG 1-7/MAS-1-dependent pathways.

scientific article published on 16 June 2010

Angiotensin converting enzyme 2 in the kidney.

scientific article published on April 2008

Angiotensin-Converting Enzyme 2 (ACE2) Is a Key Modulator of the Renin Angiotensin System in Health and Disease ⬇️

scientific article published on March 20, 2012

Angiotensin-converting enzyme 2 mediates hyperfiltration associated with diabetes

scientific article published on 29 January 2014

Angiotensin-converting enzyme 2 regulates renal atrial natriuretic peptide through angiotensin-(1-7).

scientific article published in July 2012

Antiatherosclerotic and Renoprotective Effects of Ebselen in the Diabetic Apolipoprotein E/GPx1-Double Knockout Mouse ⬇️

scientific article published on September 7, 2010

Association between intrarenal arterial resistance and diastolic dysfunction in type 2 diabetes

scientific article published on 23 May 2008

Association of dietary sodium intake with atherogenesis in experimental diabetes and with cardiovascular disease in patients with Type 1 diabetes

scientific article published in May 2013

Association of the SLC22A1, SLC22A2, and SLC22A3 genes encoding organic cation transporters with diabetic nephropathy and hypertension

scientific article

Associations between dietary fiber and inflammation, hepatic function, and risk of type 2 diabetes in older men: potential mechanisms for the benefits of fiber on diabetes risk.

scientific article published on 23 July 2009

Bardoxolone: augmenting the Yin in chronic kidney disease.

scientific article published in October 2011

Beyond Glycosuria: Exploring the intrarenal effects of SGLT₋₂ inhibition in diabetes.

scientific article published on December 2014

Blood lipid levels in New Zealand

scientific article

Blood pressure control and risk of incident atrial fibrillation.

scientific article published on 28 August 2008

Blood pressure lowering for the prevention and treatment of diabetic kidney disease.

scientific article

Budesonide substitution in Crohn's disease relieves CNS toxicity of systemic steroids

scientific article published on 01 November 1998

COX-2 inhibitors and renal failure: the triple whammy revisited

scientific article published on 01 September 2000

Candesartan attenuates diabetic retinal vascular pathology by restoring glyoxalase-I function

scientific article

Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs.

scientific article published on 13 May 2008

Changing epidemiology of type 2 diabetes mellitus and associated chronic kidney disease

scientific article

Circulating ACE2 activity is increased in patients with type 1 diabetes and vascular complications

scientific article published in February 2012

Circulating high-molecular-weight RAGE ligands activate pathways implicated in the development of diabetic nephropathy

scientific article published on 12 May 2010

Coeliac disease, gluten-free diet and the development and progression of albuminuria in children with type 1 diabetes

scientific article published on 14 June 2013

Competing-risk analysis of ESRD and death among patients with type 1 diabetes and macroalbuminuria

scientific article

Connective tissue growth factor plays an important role in advanced glycation end product-induced tubular epithelial-to-mesenchymal transition: implications for diabetic renal disease.

scientific article published on 16 August 2006

Contextualizing Genetics for Regional Heart Failure Care

scientific article

Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis

scientific article published on 28 January 2016

Delayed intervention with AGE inhibitors attenuates the progression of diabetes-accelerated atherosclerosis in diabetic apolipoprotein E knockout mice.

scientific article

Developmental expression of ACE2 in the SHR kidney: a role in hypertension?

scientific article

Diabetes: Assessing renal risk in patients with type 2 diabetes

scientific article published on 17 September 2013

Diabetes: bardoxolone improves kidney function in type 2 diabetes

scientific article published on 23 August 2011

Diabetic kidney disease.

scientific article published on 30 July 2015

Diastolic dysfunction is associated with anaemia in patients with Type II diabetes

scientific article published in January 2006

Dicarbonyl stress in the absence of hyperglycemia increases endothelial inflammation and atherogenesis similar to that observed in diabetes

scientific article published on 8 May 2014

Dietary salt intake and mortality in patients with type 2 diabetes. ⬇️

scientific article

Disparate effects on renal and oxidative parameters following RAGE deletion, AGE accumulation inhibition, or dietary AGE control in experimental diabetic nephropathy.

scientific article published on 16 December 2009

Disseminated strongyloidiasis arising from a single dose of dexamethasone before stereotactic radiosurgery

scientific article published on 01 October 1998

Distinguishing hyperglycemic changes by Set7 in vascular endothelial cells

scientific article

Diuretics, ACE inhibitors and NSAIDs--the triple whammy.

scientific article

Does a nephron deficit exacerbate the renal and cardiovascular effects of obesity?

scientific article

Early peri-operative glycaemic control and allograft rejection in patients with diabetes mellitus: a pilot study.

scientific article

Early peri-operative hyperglycaemia and renal allograft rejection in patients without diabetes

scientific article

Early vitamin E supplementation attenuates diabetes-associated vascular dysfunction and the rise in protein kinase C-beta in mesenteric artery and ameliorates wall stiffness in femoral artery of Wistar rats.

scientific article

Effects of Diabetes Medications Targeting the Incretin System on the Kidney.

scientific article published on 10 January 2018

Emerging drugs for managing kidney disease in patients with diabetes.

scientific article published on 21 January 2013

Epigenetic Mechanisms in Diabetic Kidney Disease

scientific article published on March 2016

Excess Mortality in Patients With Type 1 Diabetes Without Albuminuria-Separating the Contribution of Early and Late Risks

scientific article

Four cases of CMV ureteritis: emergence of a new pattern of disease?

scientific article published on 01 October 2001

Functional erythropoietin deficiency in patients with Type 2 diabetes and anaemia

scientific article published on 01 May 2006

Genetic Ace2 deficiency accentuates vascular inflammation and atherosclerosis in the ApoE knockout mouse.

scientific article published on 29 July 2010

Genetic Deletion of Cell Division Autoantigen 1 Retards Diabetes-Associated Renal Injury ⬇️

scientific article published on 08 August 2013

Glycated and carboxy-methylated proteins do not directly activate human vascular smooth muscle cells.

scientific article published in December 2005

Glycemic exposure, glycemic control, and metabolic karma in diabetic complications.

scientific article published on May 2014

HaNDL syndrome after "benign" OKT3-induced meningitis

scientific article published on 01 May 1999

Heart Failure in Minority Populations - Impediments to Optimal Treatment in Australian Aborigines.

scientific article published on 6 June 2016

High glucose-induced impairment in insulin secretion is associated with reduction in islet glucokinase in a mouse model of susceptibility to islet dysfunction

scientific article published on August 2005

High-salt diet increases glomerular ACE/ACE2 ratio leading to oxidative stress and kidney damage

scientific article published on 29 October 2011

Identification of angiotensin converting enzyme 2 in the rodent retina.

scientific article

Identification of obesity in patients with type 2 diabetes from Australian primary care: the NEFRON-5 study

scientific article published on 01 December 2006

Imbalance of the renin-angiotensin system may contribute to inflammation and fibrosis in IBD: a novel therapeutic target?

scientific article published on 13 August 2019

Improved islet morphology after blockade of the renin- angiotensin system in the ZDF rat.

scientific article published in April 2004

Increased thrombotic vascular events after change of statin

scientific article published on 01 December 1998

Interaction of diabetes and ACE2 in the pathogenesis of cardiovascular disease in experimental diabetes

scientific article published on 01 October 2012

Interactions between growth factors in the kidney: implications for progressive renal injury

scientific article published on 01 April 2003

Interactions between renin angiotensin system and advanced glycation in the kidney.

scientific article published on 17 August 2005

Into the light? Diabetic nephropathy and vitamin D ⬇️

scientific article published on November 6, 2010

Is nonalbuminuric renal insufficiency in type 2 diabetes related to an increase in intrarenal vascular disease?

scientific article published on 01 July 2006

Is there a role for plant-made vaccines in the prevention of HIV/AIDS?

scientific article

John Thomas sign: common distraction or useful pointer?

scientific article published in December 1998

Longitudinal analysis of low-molecular weight fluorophores in type 1 diabetes mellitus

scientific article published in February 2008

Low molecular weight advanced glycation end products predict mortality in asymptomatic patients receiving chronic haemodialysis.

scientific article published on 6 March 2006

Low testosterone levels are common and associated with insulin resistance in men with diabetes.

scientific article published on 4 March 2008

Low-molecular weight advanced glycation end products: markers of tissue AGE accumulation and more?

scientific article

Lung function and risk of type 2 diabetes and fatal and nonfatal major coronary heart disease events: possible associations with inflammation

scientific article

Lymphocytes promote albuminuria, but not renal dysfunction or histological damage in a mouse model of diabetic renal injury.

scientific article published on 27 April 2010

MK-767. Kyorin/Banyu/Merck.

scientific article

Management of patients with diabetes and CKD: conclusions from a "Kidney Disease: Improving Global Outcomes" (KDIGO) Controversies Conference

scientific article published on December 2016

Metabolic Karma-The Atherogenic Legacy of Diabetes: The 2017 Edwin Bierman Award Lecture

scientific article published on 01 May 2018

Metabolic syndrome in type 1 diabetes: association with diabetic nephropathy and glycemic control (the FinnDiane study).

scientific article published in August 2005

Moclobemide for menopausal flushing

scientific article (publication date: 3 September 1994)

Modulation of soluble receptor for advanced glycation end products by angiotensin-converting enzyme-1 inhibition in diabetic nephropathy.

scientific article

Molecular characterization of the kinetoplastid membrane protein-11 genes from the parasite Trypanosoma rangeli

scientific article published on 01 June 2005

Non-invasive Risk Stratification for Coronary Artery Disease: Is It Time for Subclassifications?

scientific article published on 25 July 2019

Nonalbuminuric renal impairment in type 2 diabetic patients and in the general population (national evaluation of the frequency of renal impairment cO-existing with NIDDM [NEFRON] 11).

scientific article published on 26 May 2009

Noradrenaline-producing renal-cell carcinoma: a unique cause of endocrine hypertension

scientific article published on 01 July 1998

Northern Territory perspectives on heart failure with comorbidities – understanding trial validity and exploring collaborative opportunities to broaden the evidence base

scientific article

Nutrient Sensing, Autophagy, and Diabetic Nephropathy ⬇️

scientific article published on January 1, 2012

On the water's edge ⬇️

scientific article published on 01 December 1997

Origin of the Y Chromosome Influences Intrarenal Vascular Responsiveness to Angiotensin I and Angiotensin (1-7) in Stroke-Prone Spontaneously Hypertensive Rats

article

Osteopontin is a strong predictor of incipient diabetic nephropathy, cardiovascular disease, and all-cause mortality in patients with type 1 diabetes

scientific article published on 26 June 2014

Osteoprotegerin increases in metabolic syndrome and promotes adipose tissue proinflammatory changes

scientific article published on 3 July 2014

Osteoprotegerin is an independent predictor of vascular events in Finnish adults with type 1 diabetes

scientific article published on July 2013

Osteoprotegerin promotes vascular fibrosis via a TGF-β1 autocrine loop

scientific article published on 27 May 2011

Ozonolysis of phospholipid double bonds during electrospray ionization: a new tool for structure determination

scientific article published on 01 January 2006

Pathogenesis and Progression of Proteinuria ⬇️

scientific article published on 09 June 2011

Perioperative blood pressure control, delayed graft function, and acute rejection after renal transplantation

scientific article published on 01 June 2003

Perspective Review: Type 2 Diabetes and Readmission for Heart Failure.

scientific article

Perspectives On Optimizing Chronic Heart Failure Care Beyond Randomised Controlled Trials - What do we Consolidate and how do we Plan for the Future?

scientific article published on 01 January 2019

Phase 4 Studies in Heart Failure - What is Done and What is Needed?

scientific article

Plasma low-molecular weight fluorescence in type 1 diabetes mellitus.

scientific article published in June 2005

Post-translational modification of plant-made foreign proteins; glycosylation and beyond ⬇️

scientific article published on 03 August 2011

Potential reno-protective effects of a gluten-free diet in type 1 diabetes.

scientific article published on 14 February 2009

Prevalence and predictors of cardiac hypertrophy and dysfunction in patients with Type 2 diabetes

scientific article published in February 2008

Quinapril treatment abolishes diabetes-associated atherosclerosis in RAGE/apolipoprotein E double knockout mice.

scientific article published on 4 June 2014

RAGE Deletion Confers Renoprotection by Reducing Responsiveness to Transforming Growth Factor-β and Increasing Resistance to Apoptosis

scientific article published on 15 February 2018

Receptor for AGEs (RAGE) blockade may exert its renoprotective effects in patients with diabetic nephropathy via induction of the angiotensin II type 2 (AT2) receptor.

scientific article published on 15 July 2010

Relationship Between Plasma 8-OH-Deoxyguanosine and Cardiovascular Disease and Survival in Type 2 Diabetes Mellitus: Results From the ADVANCE Trial.

scientific article published on 30 June 2018

Relationship between levels of advanced glycation end products and their soluble receptor and adverse outcomes in adults with type 2 diabetes.

scientific article published on 7 August 2015

Renal effects of dapagliflozin in patients with type 2 diabetes

scientific article

Response to Comment on: Ekinci et al. Dietary Salt Intake and Mortality in Patients With Type 2 Diabetes. Diabetes Care 2011;34:703–709.

scientific article published on 17 June 2011

Resveratrol Inhibits Growth of Experimental Abdominal Aortic Aneurysm Associated With Upregulation of Angiotensin-Converting Enzyme 2.

scientific article published on 21 September 2017

Risk of coronary artery disease and stroke according to sex and presence of diabetic nephropathy in type 1 diabetes

scientific article published on 07 August 2018

Role of MKK3-p38 MAPK signalling in the development of type 2 diabetes and renal injury in obese db/db mice.

scientific article

Role of advanced glycation end products in diabetic nephropathy.

scientific article

Role of bone-marrow- and non-bone-marrow-derived receptor for advanced glycation end-products (RAGE) in a mouse model of diabetes-associated atherosclerosis

scientific article published on 01 October 2014

Role of the renin-angiotensin system in the endocrine pancreas: implications for the development of diabetes.

scientific article

Running repairs: renal artery dissection following extreme exertion

scientific article published on 01 May 1999

SGLT2 inhibition with dapagliflozin -- a novel approach for the management of type 2 diabetes

scientific article

Screening for chronic kidney disease in patients with diabetes: are we missing the point?

scientific article published on 27 November 2007

Serum adiponectin concentration is a positive predictor of all-cause and cardiovascular mortality in type 1 diabetes

scientific article published on 23 June 2011

Simultaneous presentation of Goodpasture's disease and insulin-dependent diabetes mellitus

scientific article published on 01 August 1999

Sister Joseph's nodule in non-Hodgkin's lymphoma

scientific article published on 01 January 1998

Soluble receptor for AGE (RAGE) is a novel independent predictor of all-cause and cardiovascular mortality in type 1 diabetes

scientific article published on 24 May 2011

Superior renoprotective effects of combination therapy with ACE and AGE inhibition in the diabetic spontaneously hypertensive rat.

scientific article

Suppression of microRNA-29 Expression by TGF-β1 Promotes Collagen Expression and Renal Fibrosis ⬇️

scientific article published on November 17, 2011

Systematic Literature Review of DPP-4 Inhibitors in Patients with Type 2 Diabetes Mellitus and Renal Impairment

scientific article

TNF-related apoptosis-inducing ligand significantly attenuates metabolic abnormalities in high-fat-fed mice reducing adiposity and systemic inflammation.

scientific article published in November 2012

Targeted reduction of advanced glycation improves renal function in obesity

scientific article published on 16 March 2011

Targets to retard the progression of diabetic nephropathy.

scientific article

The CARI guidelines. Prevention of progression of kidney disease

scientific article published on 01 April 2006

The CARI guidelines. Prevention of progression of kidney disease: autosomal-dominant polycystic kidney disease.

scientific article published on February 2007

The CARI guidelines. Prevention of progression of kidney disease: regular and frequent follow-up of patients with pre-end-stage kidney disease

scientific article published on 01 February 2007

The CARI guidelines. Prevention of progression of kidney disease: weight reduction in obese patients with chronic kidney disease

scientific article published on February 2007

The Long-Term Incidence of Hospitalization for Ketoacidosis in Adults with Established T1D-A Prospective Cohort Study

scientific article published on 01 January 2020

The Renoprotective Actions of Peroxisome Proliferator-Activated Receptors Agonists in Diabetes ⬇️

scientific article published on February 12, 2012

The accuracy of cystatin C and commonly used creatinine-based methods for detecting moderate and mild chronic kidney disease in diabetes

scientific article published on 01 April 2007

The actions of SGLT2 inhibitors on metabolism, renal function and blood pressure

scientific article published on 22 August 2018

The arterial depressor response to chronic low-dose angiotensin II infusion in female rats is estrogen dependent

scientific article published on 26 October 2011

The assessment of kidney function by general practitioners in Australian patients with type 2 diabetes (NEFRON-2).

scientific article published in September 2006

The association between dietary sodium intake, ESRD, and all-cause mortality in patients with type 1 diabetes ⬇️

scientific article

The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes.

scientific article published on 18 July 2003

The burden of anaemia in type 2 diabetes and the role of nephropathy: a cross-sectional audit.

scientific article published on 21 April 2004

The effects of valsartan on the accumulation of circulating and renal advanced glycation end products in experimental diabetes.

scientific article published in November 2004

The endothelin receptor antagonist avosentan ameliorates nephropathy and atherosclerosis in diabetic apolipoprotein E knockout mice.

scientific article published on 28 October 2009

The epidemiology of hemoglobin levels in patients with type 2 diabetes.

scientific article published in October 2006

The high prevalence of anemia in diabetes is linked to functional erythropoietin deficiency.

scientific article published on July 2006

The impact of reference pricing on clinical lipid control

scientific article published in August 1998

The intestinal vitamin D receptor in inflammatory bowel disease: inverse correlation with inflammation but no relationship with circulating vitamin D status

scientific article published on 18 January 2019

The molecular mediators of type 2 epithelial to mesenchymal transition (EMT) and their role in renal pathophysiology.

scientific article published on 27 May 2010

The pleiotropic actions of rosuvastatin confer renal benefits in the diabetic Apo-E knockout mouse.

scientific article published on 16 June 2010

The potential and pitfalls of GLP-1 receptor agonists for renal protection in type 2 diabetes.

scientific article published on April 2017

The presence and severity of chronic kidney disease predicts all-cause mortality in type 1 diabetes

scientific article published on 28 April 2009

The role and management of sympathetic overactivity in cardiovascular and renal complications of diabetes ⬇️

scientific article published on July 17, 2013

The role of AGEs and AGE inhibitors in diabetic cardiovascular disease.

scientific article

The role of tubular epithelial-mesenchymal transition in progressive kidney disease.

scientific article published on January 2007

The use of oral antidiabetic agents in primary care.

scientific article published on June 2007

Transactivation of RAGE mediates angiotensin-induced inflammation and atherogenesis

scientific article published on 10 December 2018

Transforming growth factor-β1-mediated renal fibrosis is dependent on the regulation of transforming growth factor receptor 1 expression by let-7b.

scientific article published on 2 October 2013

Tubular changes in early diabetic nephropathy.

scientific article

Tubular proteinuria in mice and humans lacking the intrinsic lysosomal protein SCARB2/Limp-2

scientific article

Turning up the heat: heat shock proteins, hypertension and cardiovascular risk

scientific article published on 01 September 2002

Type 2 Diabetes and Heart Failure: Challenges and Solutions.

scientific article

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