List of works - Graziano Lolli

Active form of the protein kinase CK2 α2β2 holoenzyme is a strong complex with symmetric architecture

scientific article

An inhibitor's-eye view of the ATP-binding site of CDKs in different regulatory states.

scientific article

Binding to DNA of the RNA-polymerase II C-terminal domain allows discrimination between Cdk7 and Cdk9 phosphorylation.

scientific article published on 9 January 2009

Biochemical and cellular mechanism of protein kinase CK2 inhibition by deceptive curcumin

scientific article published on 29 October 2019

Derivatives of 3-amino-2-methylpyridine as BAZ2B Bromodomain Ligands: in silico Discovery and in crystallo Validation

scientific article

Different orientations of low-molecular-weight fragments in the binding pocket of a BRD4 bromodomain

scientific article

Discovery of BAZ2A Bromodomain Ligands

Discovery of BAZ2A bromodomain ligands.

scientific article published on 12 August 2017

Discovery of Inhibitors of Four Bromodomains by Fragment-Anchored Ligand Docking.

scientific article published in September 2017

GroEL from the psychrophilic bacterium Pseudoalteromonas haloplanktis TAC 125: molecular characterization and gene cloning.

scientific article published in October 2002

Inhibition of protein kinase CK2 by flavonoids and tyrphostins. A structural insight

scientific article

Inhibitor affinity chromatography: profiling the specific reactivity of the proteome with immobilized molecules.

scientific article published in July 2003

Inhibitory Properties of ATP-Competitive Coumestrol and Boldine Are Correlated to Different Modulations of CK2 Flexibility

scientific article published on 06 March 2019

Insight into GFPmut2 pH Dependence by Single Crystal Microspectrophotometry and X-ray Crystallography

scientific article published on 17 September 2018

Pharmacological inactivation of the prion protein by targeting a folding intermediate

scientific article published on 12 January 2021

Recognition of Cdk2 by Cdk7

scientific article published on 01 June 2007

Structural Analysis of Small-Molecule Binding to the BAZ2A and BAZ2B Bromodomains

scientific article published on 21 June 2018

Structural and functional analysis of the flexible regions of the catalytic α-subunit of protein kinase CK2.

scientific article published on 13 December 2011

Structural and functional determinants of protein kinase CK2α: facts and open questions.

scientific article published on 08 July 2011

Structural determinants of protein kinase CK2 regulation by autoinhibitory polymerization

scientific article

Structure and single crystal spectroscopy of Green Fluorescent Proteins.

scientific article

The STAS domain of mammalian SLC26A5 prestin harbours an anion-binding site

scientific article

The lysine-specific demethylase 1 is a novel substrate of protein kinase CK2.

scientific article published on 31 January 2014

The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation

scientific article

Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer

scientific article

List of works by Graziano Lolli

Active form of the protein kinase CK2 α2β2 holoenzyme is a strong complex with symmetric architecture

An inhibitor's-eye view of the ATP-binding site of CDKs in different regulatory states.

Binding to DNA of the RNA-polymerase II C-terminal domain allows discrimination between Cdk7 and Cdk9 phosphorylation.

Biochemical and cellular mechanism of protein kinase CK2 inhibition by deceptive curcumin

Derivatives of 3-amino-2-methylpyridine as BAZ2B Bromodomain Ligands: in silico Discovery and in crystallo Validation

Different orientations of low-molecular-weight fragments in the binding pocket of a BRD4 bromodomain

Discovery of BAZ2A Bromodomain Ligands

Discovery of BAZ2A bromodomain ligands.

Discovery of Inhibitors of Four Bromodomains by Fragment-Anchored Ligand Docking.

GroEL from the psychrophilic bacterium Pseudoalteromonas haloplanktis TAC 125: molecular characterization and gene cloning.

Inhibition of protein kinase CK2 by flavonoids and tyrphostins. A structural insight

Inhibitor affinity chromatography: profiling the specific reactivity of the proteome with immobilized molecules.

Inhibitory Properties of ATP-Competitive Coumestrol and Boldine Are Correlated to Different Modulations of CK2 Flexibility

Insight into GFPmut2 pH Dependence by Single Crystal Microspectrophotometry and X-ray Crystallography

Pharmacological inactivation of the prion protein by targeting a folding intermediate

Recognition of Cdk2 by Cdk7

Structural Analysis of Small-Molecule Binding to the BAZ2A and BAZ2B Bromodomains

Structural and functional analysis of the flexible regions of the catalytic α-subunit of protein kinase CK2.

Structural and functional determinants of protein kinase CK2α: facts and open questions.

Structural determinants of protein kinase CK2 regulation by autoinhibitory polymerization

Structure and single crystal spectroscopy of Green Fluorescent Proteins.

The STAS domain of mammalian SLC26A5 prestin harbours an anion-binding site

The lysine-specific demethylase 1 is a novel substrate of protein kinase CK2.

The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation

Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer