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List of works by Emma E Fairweather

An assay to measure poly(ADP ribose) glycohydrolase (PARG) activity in cells

scientific article published on 25 April 2016

Anilinoquinazoline inhibitors of the RET kinase domain-Elaboration of the 7-position.

scientific article published on 30 March 2016

Cell-active Small Molecule Inhibitors of the DNA-damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides

scientific article published on 19 November 2018

Discovery and Optimization of Allosteric Inhibitors of Mutant Isocitrate Dehydrogenase 1 (R132H IDH1) Displaying Activity in Human Acute Myeloid Leukemia Cells.

scientific article published on 5 December 2016

Enhancer Activation by Pharmacologic Displacement of LSD1 from GFI1 Induces Differentiation in Acute Myeloid Leukemia.

scientific article published in March 2018

First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to Olaparib

scientific article

Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease

scientific article published on 22 June 2018

The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity.

scientific article

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