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List of works by David W Chan

AMPK activators suppress cervical cancer cell growth through inhibition of DVL3 mediated Wnt/β-catenin signaling activity

scientific article

Aberrant Activation of ERK/FOXM1 Signaling Cascade Triggers the Cell Migration/Invasion in Ovarian Cancer Cells ⬇️

scientific article published on August 17, 2011

Activation of AMPK inhibits cervical cancer cell growth through AKT/FOXO3a/FOXM1 signaling cascade ⬇️

scientific article published on July 3, 2013

Autocrine activation of JAK2 by IL-11 promotes platinum drug resistance.

scientific article published on 17 April 2018

Bitter Melon (Momordica charantia) Extract Inhibits Tumorigenicity and Overcomes Cisplatin-Resistance in Ovarian Cancer Cells Through Targeting AMPK Signaling Cascade.

scientific article

Correction: Reduced expression of AMPK-ß1 during tumor progression enhances the oncogenic capacity of advanced ovarian cancer.

scientific article published on 4 August 2014

DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer

scientific article published on 26 April 2018

Differential functions of growth factor receptor-bound protein 7 (GRB7) and its variant GRB7v in ovarian carcinogenesis.

scientific article published on 13 April 2010

Down-regulation of Sox7 is associated with aberrant activation of Wnt/b-catenin signaling in endometrial cancer

scientific article published on December 2012

ERBB2 mutation: A promising target in non-squamous cervical cancer.

scientific article published on 23 December 2017

Epigenetic alteration of the metallothionein 1E gene in human endometrial carcinomas

scientific article

Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer

scientific article

FOXM1b, which is present at elevated levels in cancer cells, has a greater transforming potential than FOXM1c.

scientific article published on 31 January 2013

Increased expression of PITX2 transcription factor contributes to ovarian cancer progression

scientific article published on 15 May 2012

Interleukin-10 promoter polymorphisms in Southern Chinese patients with systemic lupus erythematosus ⬇️

scientific article published on June 1, 1998

LY294002 and metformin cooperatively enhance the inhibition of growth and the induction of apoptosis of ovarian cancer cells.

scientific article

Loss of MKP3 mediated by oxidative stress enhances tumorigenicity and chemoresistance of ovarian cancer cells

scientific article published on 16 July 2008

Novel Nuclear Partnering Role of EPS8 With FOXM1 in Regulating Cell Proliferation

scientific article published on 19 March 2019

Over-expression of FOXM1 transcription factor is associated with cervical cancer progression and pathogenesis

scientific article

Over-expressions of AMPK subunits in ovarian carcinomas with significant clinical implications ⬇️

scientific article published on August 16, 2012

Overexpression of FOXG1 contributes to TGF-beta resistance through inhibition of p21WAF1/CIP1 expression in ovarian cancer

scientific article published on 15 September 2009

Overexpression of the transcription factor ATF3 with a regulatory molecular signature associates with the pathogenic development of colorectal cancer.

scientific article published on 29 March 2017

PD-L1 expression is a prognostic factor in subgroups of gastric cancer patients stratified according to their levels of CD8 and FOXP3 immune markers.

scientific article

Pattern of T-cell receptor delta gene rearrangement by Southern blotting and polymerase chain reaction technique in Hong Kong Chinese patients with non-T-cell hematological malignancies

scientific article published on 01 June 1996

Reduced expression of AMPK-β1 during tumor progression enhances the oncogenic capacity of advanced ovarian cancer

scientific article

SIL/TAL1 recombination in adult T-acute lymphoblastic leukemia and T-lymphoblastic lymphoma

scientific article published on 01 December 1995

Targeting AMPK signaling in combating ovarian cancers: opportunities and challenges.

scientific article published on 12 January 2016

Targeting GRB7/ERK/FOXM1 signaling pathway impairs aggressiveness of ovarian cancer cells

scientific article

Understanding immune phenotypes in human gastric disease tissues by multiplexed immunohistochemistry

scientific article published on 12 October 2017

Zic2 synergistically enhances Hedgehog signalling through nuclear retention of Gli1 in cervical cancer cells

scientific article published on 10 June 2011

miR-137 mediates the functional link between c-Myc and EZH2 that regulates cisplatin resistance in ovarian cancer

scientific article published on 30 August 2018

p53 Promotes chemoresponsiveness by regulating hexokinase II gene transcription and metabolic reprogramming in epithelial ovarian cancer

scientific article published on 04 September 2019

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