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List of works by Randall J Kimple

A 10-year analysis of American Society For Radiation Oncology Junior Faculty Career Development Awards.

scientific article

A novel high-throughput irradiator for in vitro radiation sensitivity bioassays

scientific article

AXL Is a Logical Molecular Target in Head and Neck Squamous Cell Carcinoma

scientific article published on 12 March 2015

AXL mediates cetuximab and radiation resistance through tyrosine 821 and the c-ABL kinase pathway in head and neck cancer

scientific article published on 21 May 2020

Acute Toxicity From Breast Cancer Radiation Using Helical Tomotherapy With a Simultaneous Integrated Boost.

scientific article published on 16 March 2015

Anti-Trop2 blockade enhances the therapeutic efficacy of ErbB3 inhibition in head and neck squamous cell carcinoma.

scientific article published on 5 January 2018

Applicability of randomized trials in radiation oncology to standard clinical practice.

scientific article

Association of p16INK4a overexpression with improved outcomes in young patients with squamous cell cancers of the oral tongue

article

Beyond 'charting outcomes' in the radiation oncology match: analysis of self-reported applicant data.

scientific article published in December 2018

Biological characterization of a novel in vitro cell irradiator

scientific article published on 12 December 2017

Clinical Outcomes and Prognostic Factors of Adenoid Cystic Carcinoma of the Head and Neck.

scientific article

Clinical outcomes for larynx patients with cancer treated with refinement of high-dose radiation treatment volumes

scientific article published on 14 February 2020

Corrigendum: Potential role of the glycolytic oscillator in acute hypoxia in tumors (2015 <i>Phys. Med. Biol.</i> 60 9215)

scientific article published on 06 June 2018

Cosmetic outcomes for accelerated partial breast irradiation before surgical excision of early-stage breast cancer using single-dose intraoperative radiotherapy

scientific article

Cotargeting mTORC and EGFR Signaling as a Therapeutic Strategy in HNSCC.

scientific article published on 26 April 2017

D2 dopamine receptor activation of potassium channels is selectively decoupled by Galpha-specific GoLoco motif peptides.

scientific article published on March 2005

DEK promotes HPV-positive and -negative head and neck cancer cell proliferation.

scientific article

Defects in the Fanconi Anemia Pathway in Head and Neck Cancer Cells Stimulate Tumor Cell Invasion through DNA-PK and Rac1 Signaling.

scientific article

Defining the boundaries and expanding the utility of head and neck cancer patient derived xenografts.

scientific article published on 8 December 2016

Development and Characterization of HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinoma Tumorgrafts ⬇️

scientific article published on December 18, 2012

Effects of culture method on response to EGFR therapy in head and neck squamous cell carcinoma cells

scientific article published on 28 August 2019

Enhanced radiation sensitivity in HPV-positive head and neck cancer

scientific article published on 07 June 2013

Established and emerging fluorescence-based assays for G-protein function: heterotrimeric G-protein alpha subunits and regulator of G-protein signaling (RGS) proteins.

scientific article published in June 2003

FGFR inhibition enhances sensitivity to radiation in non-small cell lung cancer

scientific article published on 05 May 2020

First use of electromagnetic setup and real-time tracking in a pediatric patient with vaginal rhabdomyosarcoma

scientific article

G alpha selectivity and inhibitor function of the multiple GoLoco motif protein GPSM2/LGN

scientific article published on 01 September 2005

Genomics Reloaded: Rise of the Expression Profiles

scientific article published on 01 May 2018

Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif.

scientific article published on March 2004

HPV impacts survival of stage IVC non-oropharyngeal HNSCC cancer patients

scientific article published on 24 February 2018

High-throughput detection of DNA double-strand breaks using image cytometry

scientific article published on January 2015

Human papillomavirus and head and neck cancer

scientific article published on 01 June 2015

Human papillomavirus type 16 E7 oncoprotein causes a delay in repair of DNA damage

scientific article published on 9 September 2014

Identity Crisis - Rigor and Reproducibility in Human Cell Lines

scientific article published on 13 April 2018

Impact of HPV Status on the Prognostic Potential of the AJCC Staging System for Larynx Cancer

scientific article published in April 2018

Improved survival with dose-escalated radiotherapy in stage III non-small-cell lung cancer: analysis of the National Cancer Database.

scientific article published on 8 August 2016

In Reply to Hamstra

scientific article published on 01 April 2018

Influence of handling conditions on the establishment and propagation of head and neck cancer patient derived xenografts

scientific article

Is radiation dose reduction the right answer for HPV-positive head and neck cancer?

scientific article

Local control following single-dose intraoperative radiotherapy prior to surgical excision of early-stage breast cancer

scientific article published on 01 April 2011

Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC.

scientific article

MERTK Mediates Intrinsic and Adaptive Resistance to AXL-targeting Agents

scientific article published on 09 August 2018

Mechanism of lapatinib-mediated radiosensitization of breast cancer cells is primarily by inhibition of the Raf>MEK>ERK mitogen-activated protein kinase cascade and radiosensitization of lapatinib-resistant cells restored by direct inhibition of MEK

scientific article

Melanoma cells show a heterogeneous range of sensitivity to ionizing radiation and are radiosensitized by inhibition of B-RAF with PLX-4032.

scientific article

Merkel Cell Carcinoma Analysis of Outcomes: A 30-Year Experience

scientific article published on 8 June 2015

Modulation of therapeutic sensitivity by human papillomavirus

scientific article

Normal tissue tolerance for high-grade gliomas: is it an issue?

scientific article published on July 2009

On the importance of prompt oxygen changes for hypofractionated radiation treatments.

scientific article published on 24 September 2013

Online patient information from radiation oncology departments is too complex for the general population.

scientific article

Overcoming resistance to cetuximab with honokiol, a small-molecule polyphenol

scientific article published on 20 October 2017

Pan-HER Inhibitor Augments Radiation Response in Human Lung and Head and Neck Cancer Models.

scientific article published on 29 September 2015

Patient Derived Models to Study Head and Neck Cancer Radiation Response

scientific article published on 12 February 2020

Patient-Derived Cancer Organoid Cultures to Predict Sensitivity to Chemotherapy and Radiation

scientific article published on 07 June 2019

Phase 2 study of pre-excision single-dose intraoperative radiation therapy for early-stage breast cancers: six-year update with application of the ASTRO accelerated partial breast irradiation consensus statement criteria

scientific article published on 29 January 2013

Phase I study and biomarker analysis of lapatinib and concurrent radiation for locally advanced breast cancer.

scientific article

Potential Mechanisms of Vascular Thrombosis after Microwave Ablation in an in Vivo Liver.

scientific article published on 26 April 2017

Potential role of the glycolytic oscillator in acute hypoxia in tumors.

scientific article published on 18 November 2015

Prevalence of Human Papillomavirus in Oropharyngeal Cancer: A Systematic Review

scientific article

Prevalence of human papillomavirus in oropharyngeal squamous cell carcinoma in the United States across time.

scientific article published on 02 April 2014

Primary intracranial leiomyosarcoma in an immunocompetent patient: Case report and review of the literature.

scientific article published on 6 January 2018

Prognostic implications of human papillomavirus status for patients with non-oropharyngeal head and neck squamous cell carcinomas.

scientific article

Purification and in vitro functional analyses of RGS12 and RGS14 GoLoco motif peptides.

scientific article published in January 2004

RGS14 is a mitotic spindle protein essential from the first division of the mammalian zygote

scientific journal article

Radiation Promptly Alters Cancer Live Cell Metabolic Fluxes: An In Vitro Demonstration.

scientific article published on 29 April 2016

Radiosensitization of adenoid cystic carcinoma with MDM2 inhibition.

scientific article

Readability of Online Patient Educational Resources Found on NCI-Designated Cancer Center Web Sites

scientific article published in June 2016

Return of the GDI: the GoLoco motif in cell division.

scientific article

Review of the clinical and biologic aspects of human papillomavirus-positive squamous cell carcinomas of the head and neck

scientific article published on March 2014

SU-E-J-196: In-Vivo Tumor Blood-Oxygen Content Measurement via Interstitial Optical Transmission Spectroscopy

scientific article published on 01 June 2012

SU-E-J-197: A Novel Optical Interstitial Fiber Spectroscopic System for Real-Time Tissue Micro-Vascular Hemodynamics Monitoring

scientific article published on 01 June 2012

Small cell carcinoma of the head and neck: An analysis of the National Cancer Database.

scientific article published on 25 April 2017

Strategizing the clone wars: pharmacological control of cellular sensitivity to radiation.

scientific article published on December 2010

Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits

scientific article published on 25 April 2002

Survival Outcomes for Patients With T3N0M0 Squamous Cell Carcinoma of the Glottic Larynx

scientific article

Targeting the HER Family with Pan-HER Effectively Overcomes Resistance to Cetuximab

scientific article published on 15 July 2016

The GoLoco motif: heralding a new tango between G protein signaling and cell division.

scientific article published on April 2002

The Resident Individual Development Plan as a Guide for Radiation Oncology Mentorship

scientific article published on 06 March 2018

The Second Stain: A Viral Whodunnit.

scientific article published in December 2017

The prognostic value of HPV in head and neck cancer patients undergoing postoperative chemoradiotherapy

scientific article published on May 2015

The receptor tyrosine kinase AXL mediates nuclear translocation of the epidermal growth factor receptor

retracted scientific article published on 3 January 2017

The role of chemoradiation for patients with resectable or potentially resectable pancreatic cancer ⬇️

scientific article published on April 1, 2012

Therapeutic combination of radiolabeled CLR1404 with external beam radiation in head and neck cancer model systems

scientific article

Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos

scientific article

Value of Elective Radiation Oncology Rotations: How Many Is Too Many?

scientific article published on 6 November 2017

Wetting the whistle: neurotropic factor improves salivary function.

scientific article

Xenograft assessment of predictive biomarkers for standard head and neck cancer therapies

scientific article published on 26 January 2015

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