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List of works by Pedro Rosa-Neto

A Kinome-Wide Selective Radiolabeled TrkB/C Inhibitor for in Vitro and in Vivo Neuroimaging: Synthesis, Preclinical Evaluation, and First-in-Human

scientific article published on 11 July 2017

A dataset of multiresolution functional brain parcellations in an elderly population with no or mild cognitive impairment

scientific article

APOEε4 potentiates the relationship between amyloid-β and tau pathologies

scientific article published on 11 March 2020

Age- and gender-related differences in the cortical anatomical network

scientific article

Age-related alterations in the modular organization of structural cortical network by using cortical thickness from MRI.

scientific article published on 14 January 2011

Amyloid and tau signatures of brain metabolic decline in preclinical Alzheimer's disease

scientific article published on 2 February 2018

Amyloid-beta modulates the association between neurofilament light chain and brain atrophy in Alzheimer's disease

scientific article published on 26 June 2020

Amyloid-β and hyperphosphorylated tau synergy drives metabolic decline in preclinical Alzheimer's disease.

scientific article published on 29 March 2016

Angiotensin II type 1 receptor blocker losartan prevents and rescues cerebrovascular, neuropathological and cognitive deficits in an Alzheimer's disease model

scientific article

Anosognosia predicts default mode network hypometabolism and clinical progression to dementia

scientific article published on 14 February 2018

Atlas-based whole brain white matter analysis using large deformation diffeomorphic metric mapping: application to normal elderly and Alzheimer's disease participants

scientific article

Atlas-guided tract reconstruction for automated and comprehensive examination of the white matter anatomy

scientific article

Aβ-induced vulnerability propagates via the brain's default mode network

scientific article published on 04 June 2019

Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer's disease progression

scientific article published on 20 May 2019

Bi-directional Association of Cerebrospinal Fluid Immune Markers with Stage of Alzheimer's Disease Pathogenesis

scientific article published on 11 April 2018

Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts

scientific article published on 01 May 2020

Brain regional alpha-[11C]methyl-L-tryptophan trapping, used as an index of 5-HT synthesis, in healthy adults: absence of an age effect

scientific article published on 21 February 2007

CYP2C19 variant mitigates Alzheimer disease pathophysiology in vivo and postmortem

scientific article published on 30 January 2018

Canadian Consensus Guidelines on Use of Amyloid Imaging in Canada: Update and Future Directions from the Specialized Task Force on Amyloid imaging in Canada

scientific article

Characterizing biomarker features of cognitively normal individuals with ventriculomegaly

scientific article published on 5 September 2017

Cholinergic Depletion in Alzheimer’s Disease Shown by [18F]FEOBV Autoradiography ⬇️

scientific article published on November 10, 2013

Cholinergic Potentiation Improves Perceptual-Cognitive Training of Healthy Young Adults in Three Dimensional Multiple Object Tracking

scientific article published on 21 March 2017

Cholinergic modulation of binocular vision

scientific article published on 25 May 2020

Clinical applications of neuroimaging in patients with Alzheimer's disease: a review from the Fourth Canadian Consensus Conference on the Diagnosis and Treatment of Dementia 2012.

scientific article published on 08 July 2013

Common Effects of Amnestic Mild Cognitive Impairment on Resting-State Connectivity Across Four Independent Studies

scientific article

Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor gamma agonist

scientific article

Concordance between in vivo and postmortem measurements of cholinergic denervation in rats using PET with [18F]FEOBV and choline acetyltransferase immunochemistry

scientific article published on 9 October 2013

Consensus guidelines for lumbar puncture in patients with neurological diseases

scientific article

Correction: White Matter Abnormalities and Structural Hippocampal Disconnections in Amnestic Mild Cognitive Impairment and Alzheimer’s Disease.

scientific article published on 31 December 2013

Correlation between serotonin synthesis and 5-HT1A receptor binding in the living human brain: a combined alpha-[11C]MT and [18F]MPPF positron emission tomography study

scientific article published on 17 May 2008

Deficit in Central Auditory Processing as a Biomarker of Pre-Clinical Alzheimer's Disease

scientific article

Deficit in sustained attention following selective cholinergic lesion of the pedunculopontine tegmental nucleus in rat, as measured with both post-mortem immunocytochemistry and in vivo PET imaging with [¹⁸F]fluoroethoxybenzovesamicol

scientific article

Deletion of the mu opioid receptor gene in mice reshapes the reward-aversion connectome

scientific article

Dementia: Disclosure of results to participants in dementia research

scientific article published on 22 October 2013

Design, construction, and validation of an MRI-compatible vibrotactile stimulator intended for clinical use.

scientific article

Developments in Tau PET Imaging

scientific article

Diagnosis and management of Alzheimer's disease: Past, present and future ethical issues ⬇️

scientific article published on 08 April 2013

Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer's Disease Neuroimaging Initiative

scientific article published on 26 October 2020

Dissociation between brain amyloid deposition and metabolism in early mild cognitive impairment

scientific article

Distinct increased metabotropic glutamate receptor type 5 (mGluR5) in temporal lobe epilepsy with and without hippocampal sclerosis

scientific article

Effect of age on markers for monoaminergic neurons of normal and MPTP-lesioned rhesus monkeys: a multi-tracer PET study

scientific article published on 27 December 2005

Effects of acute nicotine on hemodynamics and binding of [11C]raclopride to dopamine D2,3 receptors in pig brain

scientific article published in July 2003

Efficient radiosynthesis and preclinical evaluation of [18 F]FOMPyD as a positron emission tomography tracer candidate for TrkB/C receptor imaging

scientific article published on 29 January 2020

Epistasis analysis links immune cascades and cerebral amyloidosis

scientific article

Ethical Considerations for the Use of Next-Generation Alzheimer Drugs in Symptomatic and At-Risk Patients

scientific article

First-in-Human Brain Imaging of [18F]TRACK, a PET tracer for Tropomyosin Receptor Kinases

scientific article published on 29 April 2019

Fluid and imaging biomarkers for Alzheimer's disease: Where we stand and where to head to.

scientific article published on 4 January 2018

Fluid biomarkers for diagnosing dementia: rationale and the Canadian Consensus on Diagnosis and Treatment of Dementia recommendations for Canadian physicians

scientific article

Gradients of dopamine D1- and D2/3-binding sites in the basal ganglia of pig and monkey measured by PET.

scientific article

How Can We Improve Transfer of Outcomes from Randomized Clinical Trials to Clinical Practice with Disease-Modifying Drugs in Alzheimer's Disease? ⬇️

scientific article published on 07 August 2013

Human brain white matter atlas: identification and assignment of common anatomical structures in superficial white matter

scientific article published on 18 July 2008

INTREPAD: A randomized trial of naproxen to slow progress of presymptomatic Alzheimer disease

scientific article

Identification of [18F]TRACK, a Fluorine-18-Labeled Tropomyosin Receptor Kinase (Trk) Inhibitor for PET Imaging

scientific article published on 19 December 2017

Identifying incipient dementia individuals using machine learning and amyloid imaging

scientific article published on 11 July 2017

Imaging Alzheimer's disease pathophysiology with PET.

scientific article published in April 2016

Imaging biomarkers for amyloid: a new generation of probes and what lies ahead

scientific article published on 13 February 2014

Imaging in vivo glutamate fluctuations with [(11)C]ABP688: a GLT-1 challenge with ceftriaxone

scientific article published on 25 March 2015

Impact of scale space search on age- and gender-related changes in MRI-based cortical morphometry

scientific article published on 16 March 2012

In vivo and in vitro validation of reference tissue models for the mGluR(5) ligand [(11)C]ABP688.

scientific article published on 9 June 2010

In vivo characterization of metabotropic glutamate receptor type 5 abnormalities in behavioral variant FTD.

scientific article published on 18 January 2015

In vivo tracking of tau pathology using positron emission tomography (PET) molecular imaging in small animals

scientific article published on 15 March 2014

Intact memory in TGF-β1 transgenic mice featuring chronic cerebrovascular deficit: recovery with pioglitazone

scientific article

Intermediate flortaucipir uptake is associated with Aβ-PET and CSF tau in asymptomatic adults

scientific article published on 03 February 2020

Is ApoE ɛ 4 a good biomarker for amyloid pathology in late onset Alzheimer's disease?

scientific article

Longitudinal cerebrospinal fluid biomarker trajectories along the Alzheimer's disease continuum in the BIOMARKAPD study

scientific article published on 06 April 2019

MDMA-evoked changes in [11C]raclopride and [11C]NMSP binding in living pig brain

scientific article

MDMA-evoked changes in cerebral blood flow in living porcine brain: correlation with hyperthermia

scientific article published on September 2004

Mapping neuroreceptors at work: on the definition and interpretation of binding potentials after 20 years of progress

scientific article

Mapping the amphetamine-evoked changes in [11C]raclopride binding in living rat using small animal PET: modulation by MAO-inhibition

scientific article

Measurement of brain regional alpha-[11C]methyl-L-tryptophan trapping as a measure of serotonin synthesis in medication-free patients with major depression

scientific article

Metabotropic Glutamate Receptor Type 5 (mGluR5) Cortical Abnormalities in Focal Cortical Dysplasia Identified In Vivo With [11C]ABP688 Positron-Emission Tomography (PET) Imaging

scientific article published on 30 August 2016

Methylphenidate-evoked changes in striatal dopamine correlate with inattention and impulsivity in adolescents with attention deficit hyperactivity disorder

scientific article

MicroPET imaging and transgenic models: a blueprint for Alzheimer's disease clinical research

scientific article

MicroPET imaging of 5-HT 1A receptors in rat brain: a test-retest [18F]MPPF study

scientific article published on 15 August 2008

Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain

scientific article published on 31 March 2017

Multi-level bootstrap analysis of stable clusters in resting-state fMRI.

scientific article published on 10 March 2010

Multimodal Imaging in Rat Model Recapitulates Alzheimer's Disease Biomarkers Abnormalities.

scientific article published on 2 November 2017

Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease

scientific article

No apparent effect of naproxen on CSF markers of innate immune activation

scientific article published on 6 June 2019

Non-invasive in vivo hyperspectral imaging of the retina for potential biomarker use in Alzheimer's disease

scientific article published on 17 September 2019

Odor identification as a biomarker of preclinical AD in older adults at risk

scientific article published on 28 June 2017

PET imaging of cholinergic deficits in rats using [18F]fluoroethoxybenzovesamicol ([18F]FEOBV).

scientific article published on 25 April 2012

PET imaging with [¹⁸F]fluoroethoxybenzovesamicol ([¹⁸F]FEOBV) following selective lesion of cholinergic pedunculopontine tegmental neurons in rat.

scientific article published on 21 October 2013

Pioglitazone improves reversal learning and exerts mixed cerebrovascular effects in a mouse model of Alzheimer's disease with combined amyloid-β and cerebrovascular pathology

scientific journal article

Prevention strategies for Alzheimer's disease

scientific article

Principal component of explained variance: An efficient and optimal data dimension reduction framework for association studies

scientific article

Principal component of explained variance: an efficient and optimal data dimension reduction framework for association studies

Proximity to Parental Symptom Onset and Amyloid-β Burden in Sporadic Alzheimer Disease

scientific article published on 26 February 2018

Quantification of brain cholinergic denervation in Alzheimer's disease using PET imaging with [18F]-FEOBV.

scientific article

Radioligands for Tropomyosin Receptor Kinase (Trk) Positron Emission Tomography Imaging

scientific article published on 03 January 2019

Recommendations of the 4th Canadian Consensus Conference on the Diagnosis and Treatment of Dementia (CCCDTD4)

scientific article

Reduced metabotropic glutamate receptor 5 in the Flinders Sensitive Line of rats, an animal model of depression: an autoradiographic study

scientific article published on 31 January 2012

Regional Amyloid-β Load and White Matter Abnormalities Contribute to Hypometabolism in Alzheimer's Dementia

scholarly article by Lucas Porcello Schilling et al published 9 November 2018 in Molecular Neurobiology

Remodeling of Neuronal Circuits After Reach Training in Chronic Capsular Stroke

scientific article published on 18 May 2016

Resting state executive control network adaptations in amnestic mild cognitive impairment

scientific article published in January 2014

Revealing modular architecture of human brain structural networks by using cortical thickness from MRI.

scientific article

Role of emerging neuroimaging modalities in patients with cognitive impairment: a review from the Canadian Consensus Conference on the Diagnosis and Treatment of Dementia 2012.

scientific article published on 08 July 2013

Sensory-parietal cortical stimulation improves motor recovery in severe capsular infarct.

scientific article published on 4 November 2015

Stability of alpha-[11C]methyl-L-tryptophan brain trapping in healthy male volunteers

scientific article published on 10 June 2005

Subjective Cognitive Decline Is Associated With Altered Default Mode Network Connectivity in Individuals With a Family History of Alzheimer's Disease

scholarly article by Sander C.J. Verfaillie et al published May 2018 in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

Superficially located white matter structures commonly seen in the human and the macaque brain with diffusion tensor imaging

scientific article published in January 2011

Synergistic interaction between amyloid and tau predicts the progression to dementia

scientific article published on 23 December 2016

Syntheses and evaluation of carbon-11- and fluorine-18-radiolabeled pan-tropomyosin receptor kinase (Trk) inhibitors: exploration of the 4-aza-2-oxindole scaffold as Trk PET imaging agents

scientific article published on 10 November 2014

Targeting Alzheimer's Disease at the Right Time and the Right Place: Validation of a Personalized Approach to Diagnosis and Treatment

scientific article published in March 2018

Test-retest resting-state fMRI in healthy elderly persons with a family history of Alzheimer's disease

scientific article

Test-retest stability of cerebral mGluR₅ quantification using [¹¹C]ABP688 and positron emission tomography in rats

scientific article published on 16 March 2012

The prevalence and biomarkers' characteristic of rapidly progressive Alzheimer's disease from the Alzheimer's Disease Neuroimaging Initiative database

scientific article published on January 2017

Topographical distribution of amyloid-β, tau and atrophy in behavioral / dysexecutive AD patients

scientific article published on 22 October 2020

Towards the PET radiotracer for p75 neurotrophin receptor: [(11)C]LM11A-24 shows biological activity in vitro, but unfavorable ex vivo and in vivo profile

scientific article published on 13 August 2016

Towards tropomyosin-related kinase B (TrkB) receptor ligands for brain imaging with PET: radiosynthesis and evaluation of 2-(4-[(18)F]fluorophenyl)-7,8-dihydroxy-4H-chromen-4-one and 2-(4-([N-methyl-(11)C]-dimethylamino)phenyl)-7,8-dihydroxy-4H-chro

scientific article published on 19 October 2013

Tracking neuroinflammation in Alzheimer's disease: the role of positron emission tomography imaging

scientific article

Transgenic mice overexpressing APP and transforming growth factor-beta1 feature cognitive and vascular hallmarks of Alzheimer's disease

scientific article

Uptake and binding of the serotonin 5-HT1A antagonist [18F]-MPPF in brain of rats: effects of the novel P-glycoprotein inhibitor tariquidar

scientific article published on 28 September 2009

Use of Animal Models in Molecular Imaging

scientific article published on 14 February 2020

Use of amyloid PET across the spectrum of Alzheimer's disease: clinical utility and associated ethical issues

scientific article

Validation of a Regression Technique for Segmentation of White Matter Hyperintensities in Alzheimer's Disease

scientific article published on 12 April 2017

White matter abnormalities and structural hippocampal disconnections in amnestic mild cognitive impairment and Alzheimer's disease

scientific article

[18F]FDG PET signal is driven by astroglial glutamate transport

scientific article

[18F]SiFA-isothiocyanate: a new highly effective radioactive labeling agent for lysine-containing proteins.

scientific article published in May 2009

alpha-[11C]Methyl-L-tryptophan trapping in the orbital and ventral medial prefrontal cortex of suicide attempters

scientific article published on 2 November 2005

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