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List of works by Franck Fieschi

1,2-Mannobioside mimic: synthesis, DC-SIGN interaction by NMR and docking, and antiviral activity.

scientific article published on July 2007

A Two-component NADPH Oxidase (NOX)-like System in Bacteria Is Involved in the Electron Transfer Chain to the Methionine Sulfoxide Reductase MsrP.

scientific article published on 27 December 2016

A glycomimetic compound inhibits DC-SIGN-mediated HIV infection in cellular and cervical explant models

scientific article

A multivalent inhibitor of the DC-SIGN dependent uptake of HIV-1 and Dengue virus

scientific article published on 6 February 2014

Adenovirus-Inspired Virus-Like-Particles Displaying Melanoma Tumor Antigen Specifically Target Human DC Subsets and Trigger Antigen-Specific Immune Responses

scientific article published on 10 November 2022

Alteration of the langerin oligomerization state affects Birbeck granule formation

scientific article published on February 2015

C-terminal engineering of CXCL12 and CCL5 chemokines: functional characterization by electrophysiological recordings

scientific article (publication date: 2014)

Chemoenzymatic Synthesis of N-glycan Positional Isomers and Evidence for Branch Selective Binding by Monoclonal Antibodies and Human C-type Lectin Receptors

scientific article published on 21 June 2018

Chromophore twisting in the excited state of a photoswitchable fluorescent protein captured by time-resolved serial femtosecond crystallography

scientific article published on 11 September 2017

Conformational changes in p47(phox) upon activation highlighted by mass spectrometry coupled to hydrogen/deuterium exchange and limited proteolysis

scientific article published on 2 February 2009

CopH from Cupriavidus metallidurans CH34. A novel periplasmic copper-binding protein.

scientific article published on May 2006

Cys5 and Cys214 of NAD(P)H:flavin oxidoreductase from Escherichia coli are located in the active site.

scientific article

DC-SIGN neck domain is a pH-sensor controlling oligomerization: SAXS and hydrodynamic studies of extracellular domain.

scientific article published on 5 June 2009

Dendritic-cell-specific ICAM3-grabbing non-integrin is essential for the productive infection of human dendritic cells by mosquito-cell-derived dengue viruses

scientific article

Designing nanomolar antagonists of DC-SIGN-mediated HIV infection: ligand presentation using molecular rods

scientific article

Detection and characterization of merohedral twinning in two protein crystals: bacteriorhodopsin and p67phox

scientific article published on 26 April 2002

Detection and quantitative analysis of two independent binding modes of a small ligand responsible for DC-SIGN clustering

scientific article

Development of C-type lectin-oriented surfaces for high avidity glycoconjugates: towards mimicking multivalent interactions on the cell surface

scientific article published on 01 July 2020

Docking, synthesis, and NMR studies of mannosyl trisaccharide ligands for DC-SIGN lectin.

scientific article

Down-regulation of NOX2 activity in phagocytes mediated by ATM-kinase dependent phosphorylation.

scientific article published on 12 September 2017

Effects of p47phox C terminus phosphorylations on binding interactions with p40phox and p67phox. Structural and functional comparison of p40phox and p67phox SH3 domains

scientific article

Enhancing Potency and Selectivity of a DC-SIGN Glycomimetic Ligand by Fragment-Based Design: Structural Basis

scientific article published on 18 October 2019

Facile access to pseudo-thio-1,2-dimannoside, a new glycomimetic DC-SIGN antagonist.

scientific article published on 22 March 2017

Glycosaminoglycans are interactants of Langerin: comparison with gp120 highlights an unexpected calcium-independent binding mode

scientific article

Human Cytomegalovirus Binding to DC-SIGN Is Required for Dendritic Cell Infection and Target Cell trans-Infection

scientific article published on 01 November 2002

Human Macrophage Galactose-Type Lectin (MGL) Recognizes the Outer Core of Escherichia coli Lipooligosaccharide

scientific article published on 24 June 2019

Identification of NOX2 regions for normal biosynthesis of cytochrome b558 in phagocytes highlighting essential residues for p22phox binding

scientific article

Identification of a two-component regulatory system involved in antimicrobial peptide resistance in Streptococcus pneumoniae

scientific article published on 08 April 2022

Inhibition of DC-SIGN-mediated HIV infection by a linear trimannoside mimic in a tetravalent presentation.

scientific article

Insights into molecular recognition of Lewis(X) mimics by DC-SIGN using NMR and molecular modelling

scientific article published on 10 October 2011

Investigating alternative acidic proteases for H/D exchange coupled to mass spectrometry: plasmepsin 2 but not plasmepsin 4 is active under quenching conditions

scientific article published on 17 September 2009

Is the NAD(P)H:flavin oxidoreductase from Escherichia coli a member of the ferredoxin-NADP+ reductase family?. Evidence for the catalytic role of serine 49 residue.

scientific article

Langerin-heparin interaction: two binding sites for small and large ligands as revealed by a combination of NMR spectroscopy and cross-linking mapping experiments.

scientific article published on 23 March 2015

Leu505 of Nox2 is crucial for optimal p67phox-dependent activation of the flavocytochrome b558 during phagocytic NADPH oxidase assembly.

scientific article published on 23 October 2006

Leukotriene BLT2 receptor monomers activate the G(i2) GTP-binding protein more efficiently than dimers

scientific article

Mannose hyperbranched dendritic polymers interact with clustered organization of DC-SIGN and inhibit gp120 binding

scientific article published on 31 March 2006

Mannosylcalix[n]arenes as multivalent ligands for DC-SIGN.

scientific article published on 31 October 2017

Microbe-focused glycan array screening platform

scientific article published on 22 January 2019

Monovalent mannose-based DC-SIGN antagonists: targeting the hydrophobic groove of the receptor.

scientific article published on 31 January 2014

Multivalent glycoconjugates as anti-pathogenic agents ⬇️

scientific article

NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action

scientific article

New branched amino acids for high affinity dendrimeric DC-SIGN ligands

scientific article published on 26 December 2017

Nonhydrolyzable C-disaccharides, a new class of DC-SIGN ligands

scientific article published on 9 September 2016

OA011-03. Clusterin, a natural ligand of DC-SIGN present in human semen inhibits HIV capture and transmission by dendritic cells

article

On-Chip Screening of a Glycomimetic Library with C-Type Lectins Reveals Structural Features Responsible for Preferential Binding of Dectin-2 over DC-SIGN/R and Langerin

scientific article published on 03 September 2018

Overproduction, purification and preliminary crystallographic analysis of the carbohydrate-recognition domain of human langerin.

scientific article

Photoswitching mechanism of a fluorescent protein revealed by time-resolved crystallography and transient absorption spectroscopy

scientific article published on 06 February 2020

Polyvalent C-glycomimetics based on l-fucose or d-mannose as potent DC-SIGN antagonists

scientific article published on 01 May 2017

Rational-Differential Design of Highly Specific Glycomimetic Ligands: Targeting DC-SIGN and Excluding Langerin Recognition

scientific article published on 22 December 2017

Regulation of NADPH oxidase activity in phagocytes: relationship between FAD/NADPH binding and oxidase complex assembly

scientific article

Saturation transfer difference (STD) NMR spectroscopy characterization of dual binding mode of a mannose disaccharide to DC-SIGN.

scientific article

Second generation of fucose-based DC-SIGN ligands : affinity improvement and specificity versus Langerin

scientific article published on 07 July 2011

Selective targeting of dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN) with mannose-based glycomimetics: synthesis and interaction studies of bis(benzylamide) derivatives of a pseudomannobioside.

scientific article

Semen Clusterin Is a Novel DC-SIGN Ligand

Short Communication: Inhibition of DC-SIGN-Mediated HIV-1 Infection by Complementary Actions of Dendritic Cell Receptor Antagonists and Env-Targeting Virus Inactivators.

scientific article

Solution Behavior of Amphiphilic Glycodendrimers with a Rod-Like Core.

scientific article

Structural studies of langerin and Birbeck granule: a macromolecular organization model

scientific article

Structure of a glycomimetic ligand in the carbohydrate recognition domain of C-type lectin DC-SIGN. Structural requirements for selectivity and ligand design

scientific article

Synthesis of a selective inhibitor of a fucose binding bacterial lectin from Burkholderia ambifaria

scientific article published on June 2013

Synthesis of novel DC-SIGN ligands with an alpha-fucosylamide anchor.

scientific article published in August 2008

TETRALEC, Artificial Tetrameric Lectins: A Tool to Screen Ligand and Pathogen Interactions

scientific article published on 25 July 2020

The NAD(P)H:flavin oxidoreductase from Escherichia coli. Evidence for a new mode of binding for reduced pyridine nucleotides

scientific article published on 01 June 1999

The NOX Family of Proteins Is Also Present in Bacteria

scientific article published on 7 November 2017

The manganese-containing ribonucleotide reductase of Corynebacterium ammoniagenes is a class Ib enzyme.

scientific article published in February 1998

The mechanism and substrate specificity of the NADPH:flavin oxidoreductase from Escherichia coli.

scientific article

The unique 3D arrangement of macrophage galactose lectin enables lipopolysaccharide recognition through two distinct interfaces

scholarly article

The unique three-dimensional arrangement of Macrophage Galactose Lectin enables E. coli LipoPolySaccharides recognition through two distinct interfaces

scientific article published on 2 March 2023

Unique DC-SIGN clustering activity of a small glycomimetic: A lesson for ligand design

scientific article

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