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List of works by Claus Johansen

1alpha,25(OH)(2)D(3) regulates NF-kappaB DNA binding activity in cultured normal human keratinocytes through an increase in IkappaBalpha expression.

scientific article published on 15 September 2004

1alpha,25-dihydroxyvitamin D3 induced differentiation of cultured human keratinocytes is accompanied by a PKC-independent regulation of AP-1 DNA binding activity

scientific article published on 01 June 2000

1alpha,25-dihydroxyvitamin D3 stimulates activator protein 1 DNA-binding activity by a phosphatidylinositol 3-kinase/Ras/MEK/extracellular signal regulated kinase 1/2 and c-Jun N-terminal kinase 1-dependent increase in c-Fos, Fra1, and c-Jun express

scientific article published in April 2003

A Characterization of the expression of 14-3-3 isoforms in psoriasis, basal cell carcinoma, atopic dermatitis and contact dermatitis

scientific article

Activator protein 1 DNA binding activity is decreased in lesional psoriatic skin compared with nonlesional psoriatic skin.

scientific article published in September 2004

Adalimumab therapy rapidly inhibits p38 mitogen-activated protein kinase activity in lesional psoriatic skin preceding clinical improvement.

scientific article

Aldara®-induced skin inflammation: studies of patients with psoriasis.

scientific article

Anti-inflammatory effect of a retrovirus-derived immunosuppressive peptide in mouse models

scientific article

Antibiotics inhibit tumor and disease activity in cutaneous T-cell lymphoma

scientific article published on 22 July 2019

CCL27 expression is regulated by both p38 MAPK and IKKβ signalling pathways.

scientific article published on 10 October 2011

Caspase-5 expression is upregulated in lesional psoriatic skin

scientific article published on 30 December 2010

Changes in mRNA expression precede changes in microRNA expression in lesional psoriatic skin during treatment with adalimumab

scientific article published on 14 July 2015

Characterization of TNF-α- and IL-17A-Mediated Synergistic Induction of DEFB4 Gene Expression in Human Keratinocytes through IκBζ.

scientific article published on 24 April 2016

Characterization of the interleukin-17 isoforms and receptors in lesional psoriatic skin

scientific article

Comment on 'Tumour necrosis factor-α plays a significant role in the Aldara-induced skin inflammation in mice': reply from authors.

scientific article

Comparative Analysis of Two Gene-Targeting Approaches Challenges the Tumor-Suppressive Role of the Protein Kinase MK5/PRAK

scientific article

Differential Effects of Digoxin on Imiquimod-Induced Psoriasis-Like Skin Inflammation on the Ear and Back

scientific article published on 28 June 2018

Dimethylfumarate inhibits MIF-induced proliferation of keratinocytes by inhibiting MSK1 and RSK1 activation and by inducing nuclear p-c-Jun (S63) and p-p53 (S15) expression.

scientific article

Dimethylfumarate specifically inhibits the mitogen and stress-activated kinases 1 and 2 (MSK1/2): possible role for its anti-psoriatic effect.

scientific article

Efficacy of ustekinumab in palmoplantar pustulosis and palmoplantar pustular psoriasis

scientific article published on 25 June 2014

Expression and Localization of Peroxisome Proliferator-Activated Receptors and Nuclear Factor κB in Normal and Lesional Psoriatic Skin

Generation and Culturing of Primary Human Keratinocytes from Adult Skin.

scientific article published on 22 December 2017

IL-17F regulates psoriasis-associated genes through IκBζ.

scientific article published on 30 August 2016

IL-20 gene expression is induced by IL-1beta through mitogen-activated protein kinase and NF-kappaB-dependent mechanisms

scientific article published on 25 January 2007

IL-20, IL-21 and p40: potential biomarkers of treatment response for ustekinumab.

scientific article published in March 2013

IL-8 and p53 are inversely regulated through JNK, p38 and NF-kappaB p65 in HepG2 cells during an inflammatory response.

scientific article

Inflammasomes and inflammatory caspases in skin inflammation

scientific article

Inflammation-induced alterations in the skin barrier function: implications in atopic dermatitis.

scientific article published on 13 March 2012

Inflammatory cytokines break down intrinsic immunological tolerance of human primary keratinocytes to cytosolic DNA.

scientific article

Interleukin 20 protein locates to distinct mononuclear cells in psoriatic skin

scientific article published on 01 May 2014

Interleukin 20 regulates dendritic cell migration and expression of co-stimulatory molecules.

scientific article published on 26 January 2016

Interleukin-23 in early disease development in rheumatoid arthritis.

scientific article published on 19 June 2015

Inverse regulation of the nuclear factor-kappaB binding to the p53 and interleukin-8 kappaB response elements in lesional psoriatic skin.

scientific article published in June 2005

Investigating the Role of I Kappa B Kinase ε in the Pathogenesis of Psoriasis

scientific article published on 01 October 2019

IκBζ is a key driver in the development of psoriasis

scientific article

IκBζ: A key protein in the pathogenesis of psoriasis

scientific article

Kinetics and differential expression of the skin-related chemokines CCL27 and CCL17 in psoriasis, atopic dermatitis and allergic contact dermatitis

scientific article published on 24 June 2011

Langerhans cell markers CD1a and CD207 are the most rapidly responding genes in lesional psoriatic skin following adalimumab treatment.

scientific article

Leptin deficiency in mice counteracts imiquimod (IMQ)-induced psoriasis-like skin inflammation while leptin stimulation induces inflammation in human keratinocytes.

scientific article

Lysophosphatidylcholine induces keratinocyte differentiation and upregulation of AP-1- and NF-kappaB DNA-binding activity

scientific article published on 01 January 2004

MK2 regulates the early stages of skin tumor promotion.

scientific article published on December 2009

Measuring serum concentrations of interleukin-33 in atopic dermatitis is associated with potential false positive results.

scientific article

Mice lacking MSK1 and MSK2 show reduced skin tumor development in a two-stage chemical carcinogenesis model.

scientific article published in March 2011

MicroRNA normalization candidates for quantitative reverse-transcriptase polymerase chain reaction in real time in lesional and nonlesional psoriatic skin.

scientific article

MicroRNA-106b Regulates Expression of the Tumour Suppressors p21 and TXNIP and Promotes Tumour Cell Proliferation in Mycosis Fungoides

scientific article published on 18 June 2020

Mitogen- and stress-activated protein kinase 2 and cyclic AMP response element binding protein are activated in lesional psoriatic epidermis

scientific article published on 12 April 2007

Non-random Plaque-site Recurrence of Psoriasis in Patients Treated with Dead Sea Climatotherapy

scientific article published on 01 September 2019

Pathway Analysis of Skin from Psoriasis Patients after Adalimumab Treatment Reveals New Early Events in the Anti-Inflammatory Mechanism of Anti-TNF-α

scientific article

Preferential inhibition of the mRNA expression of p38 mitogen-activated protein kinase regulated cytokines in psoriatic skin by anti-TNFα therapy.

scientific article

Pro-inflammatory cytokine release in keratinocytes is mediated through the MAPK signal-integrating kinases.

scientific article

Prognostic miRNA classifier in early-stage mycosis fungoides: development and validation in a Danish nationwide study

scientific article published on 5 December 2017

Protein expression of TNF-alpha in psoriatic skin is regulated at a posttranscriptional level by MAPK-activated protein kinase 2.

scientific article published on February 2006

Protein phosphatase 2Cδ/Wip1 regulates phospho-p90RSK2 activity in lesional psoriatic skin.

scientific article published on 15 December 2017

Reduced oxazolone-induced skin inflammation in MAPKAP kinase 2 knockout mice.

scientific article

Role of p38 mitogen-activated protein kinase isoforms in murine skin inflammation induced by 12-O-tetradecanoylphorbol 13-acetate.

scientific article published in May 2011

STAT1 expression and activation is increased in lesional psoriatic skin

scientific article published on February 1, 2013

STAT2 is involved in the pathogenesis of psoriasis by promoting CXCL11 and CCL5 production by keratinocytes

scientific article

Studies of Jak/STAT3 expression and signalling in psoriasis identifies STAT3-Ser727 phosphorylation as a modulator of transcriptional activity.

scientific article published in May 2013

TARC augments TNF-alpha-induced CTACK production in keratinocytes.

scientific article

TNFα- and IL-17A-mediated S100A8 expression is regulated by p38 MAPK.

scientific article published in July 2013

TRIM21 is important in the early phase of inflammation in the imiquimod-induced psoriasis-like skin inflammation mouse model.

scientific article published on 11 December 2016

TSLP, IL-31, IL-33 and sST2 are new biomarkers in endophenotypic profiling of adult and childhood atopic dermatitis

scientific article published on 06 May 2016

The "Alarmins" HMBG1 and IL-33 Downregulate Structural Skin Barrier Proteins and Impair Epidermal Growth.

scientific article published on 14 October 2016

The MicroRNA Expression Profile Differs Between Erythrodermic Mycosis Fungoides and Sézary Syndrome

scientific article published on 01 November 2019

The activity of caspase-1 is increased in lesional psoriatic epidermis

scientific article published on 28 June 2007

The caspase-cleaved form of LYN mediates a psoriasis-like inflammatory syndrome in mice.

scientific article published on 09 July 2009

The expression and phosphorylation of eukaryotic initiation factor 4E are increased in lesional psoriatic skin.

scientific article published on 7 May 2009

The expression of dual-specificity phosphatase 1 mRNA is downregulated in lesional psoriatic skin.

scientific article

The human IL-17A/F heterodimer regulates psoriasis-associated genes through IκBζ

scientific article published on 29 July 2018

The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling

scientific article published in September 2008

The mitogen-activated protein kinases p38 and ERK1/2 are increased in lesional psoriatic skin

scientific article published on 01 January 2005

The p38 MAPK regulates IL-24 expression by stabilization of the 3' UTR of IL-24 mRNA.

scientific article

The role of leptin in psoriasis comprises a proinflammatory response by the dermal fibroblast

scientific article

The role of mitogen- and stress-activated protein kinase 1 and 2 in chronic skin inflammation in mice.

scientific article

Tumor necrosis factor α-mediated induction of interleukin 17C in human keratinocytes is controlled by nuclear factor κB.

scientific article

Tumor necrosis factor-alpha-induced CTACK/CCL27 (cutaneous T-cell-attracting chemokine) production in keratinocytes is controlled by nuclear factor kappaB.

scientific article

Tumour necrosis factor-α plays a significant role in the Aldara-induced skin inflammation in mice.

scientific article

Ustekinumab in the treatment of refractory chronic cutaneous lupus erythematosus: a case report

scientific article published on 01 May 2013