List of works - Terrence Deak

A Pivotal Role for Thiamine Deficiency in the Expression of Neuroinflammation Markers in Models of Alcohol-Related Brain Damage

scientific article published on 20 January 2019

A brief overview of the 2016 Neurobiology of Stress Workshop.

scientific article

A cross-sectional comparison of ethanol-related cytokine expression in the hippocampus of young and aged Fischer 344 rats

scientific article

A long-term increase in basal levels of corticosterone and a decrease in corticosteroid-binding globulin after acute stressor exposure

scientific article published on 01 December 1995

A multispecies approach for understanding neuroimmune mechanisms of stress

scientific article

A users guide to HPA axis research.

scientific article published on 18 November 2016

A working model for the assessment of disruptions in social behavior among aged rats: The role of sex differences, social recognition, and sensorimotor processes

scientific article published on 23 January 2016

Acute Stress May Facilitate Recovery from a Subcutaneous Bacterial Challenge

scientific article published on 01 September 1999

Acute illness induces the release of aversive odor cues from adult, but not prepubertal, male rats and suppresses social investigation by conspecifics.

scientific article published in October 2009

Acute illness-induced behavioral alterations are similar to those observed during withdrawal from acute alcohol exposure ⬇️

scientific article published on August 17, 2012

Acute stress imposed during adolescence has minimal effects on hypothalamic-pituitary-adrenal (HPA) axis sensitivity in adulthood in female Sprague Dawley rats

scientific article published on 18 October 2019

Acute stress imposed during adolescence yields heightened anxiety in Sprague Dawley rats that persists into adulthood: Sex differences and potential involvement of the Medial Amygdala

scientific article published on 22 August 2019

Acute stressor exposure facilitates innate immunity more in physically active than in sedentary rats.

scientific article

Adolescent Ethanol Exposure Leads to Stimulus-Specific Changes in Cytokine Reactivity and Hypothalamic-Pituitary-Adrenal Axis Sensitivity in Adulthood

scientific article

Adolescent forced swim stress increases social anxiety-like behaviors and alters kappa opioid receptor function in the basolateral amygdala of male rats

scientific article published on 07 November 2019

Adolescent forced swim stress increases social anxiety-like behaviors and alters the dynorphin/kappa opioid receptor system in the basolateral amygdala of males

Alpha-melanocyte stimulating hormone reduces putative stress-induced sickness behaviors in isolated guinea pig pups.

scientific article

Analysis of c-Fos induction in response to social interaction in male and female Fisher 344 rats.

scientific article

Anti-inflammatory influences on behavioral, but not cortisol, responses during maternal separation.

scientific article published on 25 March 2009

Assessment of Extracellular Cytokines in the Hippocampus of the Awake Behaving Rat Using Large-Molecule Microdialysis Combined with Multiplex Arrays After Acute and Chronic Ethanol Exposure

scientific article published on 11 February 2019

Assessment of social behavior directed toward sick partners and its relation to central cytokine expression in rats

scientific article published on 12 October 2017

Attractiveness of illness-associated odorant cues in female rats is modulated by ovarian hormones, but not associated with pro-inflammatory cytokine levels.

scientific article published on 21 July 2011

Behavioral and neurochemical effects of chronic L-DOPA treatment on nonmotor sequelae in the hemiparkinsonian rat ⬇️

scientific article published on October 1, 2010

Behavioral effects of peripheral corticotropin-releasing factor during maternal separation may be mediated by proinflammatory activity ⬇️

scientific article published on January 20, 2011

Central infusion of interleukin-1 receptor antagonist blocks the reduction in social behavior produced by prior stressor exposure.

scientific article published on 03 May 2009

Central neuroimmune activity and depressive-like behavior in response to repeated maternal separation and injection of LPS

scientific article published on 30 November 2018

Conditioned effects of ethanol on the immune system.

scientific article published on January 2017

Contribution of the striatum to the effects of 5-HT1A receptor stimulation in L-DOPA-treated hemiparkinsonian rats

scientific article published on May 2009

Corticosterone and progesterone differentially regulate HPA axis and neuroimmune responses to stress in male rats

scientific article published on 26 October 2019

Cross-species evidence for the role of interleukin-33 in depression risk

scientific article

Differential effects of acute versus chronic stress on ethanol sensitivity: evidence for interactions on both behavioral and neuroimmune outcomes.

scientific article published on 16 February 2018

Discrimination between changes in glucocorticoid receptor expression and activation in rat brain using western blot analysis

scientific article published on 01 June 2000

Early Attachment Disruption, Inflammation, and Vulnerability for Depression in Rodent and Primate Models

scientific article published on 01 January 2018

Early attachment-figure separation and increased risk for later depression: potential mediation by proinflammatory processes.

scientific article

Early ontogeny as a unique developmental epoch for learning, memory and consequences of alcohol exposure: A Festschrift to honor the work of Dr. Norman E. Spear

scientific article published on 8 June 2015

Effects of the estrous cycle and ovarian hormones on central expression of interleukin-1 evoked by stress in female rats

scientific article published on 2 October 2014

Endogenous glucocorticoids play a positive regulatory role in the anti-keyhole limpet hemocyanin in vivo antibody response.

scientific article

Endogenous opioids as substrates for ethanol intake in the neonatal rat: The impact of prenatal ethanol exposure on the opioid family in the early postnatal period.

scientific article published on 7 February 2015

Enhancement of the hypothalamic-pituitary-adrenal axis but not cytokine responses to stress challenges imposed during withdrawal from acute alcohol exposure in Sprague-Dawley rats

scientific article

Evidence that brief stress may induce the acute phase response in rats ⬇️

scientific article published on December 1, 1997

Exogenous corticosterone reduces L-DOPA-induced dyskinesia in the hemi-parkinsonian rat: role for interleukin-1beta.

scientific article published on 12 July 2008

Exposure to acute stress induces brain interleukin-1beta protein in the rat.

scientific article published on March 1998

Exposure to forced swim stress does not alter central production of IL-1.

scientific article published in May 2003

Factors promoting vulnerability to dysregulated stress reactivity and stress-related disease

scientific article published on 07 October 2018

From adolescence to late aging: A comprehensive review of social behavior, alcohol, and neuroinflammation across the lifespan

scientific article published on 24 August 2019

From hippocampus to dorsal horn: the pervasive impact of IL-1 on learning and memory spans the length of the neuroaxis.

scientific article published on 9 May 2007

From models to mechanisms: odorant communication as a key determinant of social behavior in rodents during illness-associated states.

scientific article published on 15 March 2011

Gene expression changes in the hypothalamus provide evidence for regionally-selective changes in IL-1 and microglial markers after acute stress

scientific journal article

Highlight Article: Conditioning the neuroimmune response to ethanol using taste and environmental cues in adolescent and adult rats

scientific article published on 26 February 2019

Immune cells and cytokine circuits: toward a working model for understanding direct immune-to-adrenal communication pathways.

scientific article published on April 2008

Impact of housing conditions on social behavior, neuroimmune markers, and oxytocin receptor expression in aged male and female Fischer 344 rats

scientific article published on 14 May 2019

Late aging alters behavioral sensitivity to ethanol in a sex-specific manner in Fischer 344 rats

scientific article published on 29 August 2018

Late aging-associated increases in L-DOPA-induced dyskinesia are accompanied by heightened neuroinflammation in the hemi-parkinsonian rat

scientific article published on 31 May 2019

Long-term changes in mineralocorticoid and glucocorticoid receptor occupancy following exposure to an acute stressor.

scientific article published on November 1999

Male adolescent rats display blunted cytokine responses in the CNS after acute ethanol or lipopolysaccharide exposure

scientific article

Maternal inhibition of infant behavioral response following isolation in novel surroundings and inflammatory challenge ⬇️

scientific article published on May 9, 2012

Maternal separation increases later immobility during forced swim in guinea pig pups: evidence for sensitization of a depressive-like state

scientific article published on 04 July 2016

Maternal separation produces, and a second separation enhances, core temperature and passive behavioral responses in guinea pig pups.

scientific article

Naproxen attenuates sensitization of depressive-like behavior and fever during maternal separation.

scientific article

Neuroendocrine and neuroimmune adaptation to Chronic Escalating Distress (CED): A novel model of chronic stress

scientific article published on 18 August 2018

Neuroimmune mechanisms of stress: sex differences, developmental plasticity, and implications for pharmacotherapy of stress-related disease

scientific article

Novel aspects of glucocorticoid actions

scientific article

On the time course, generality, and regulation of plasma progesterone release in male rats by stress exposure.

scientific article published on 13 June 2014

Oxytocin and vasopressin in the medial amygdala differentially modulate approach and avoidance behavior toward illness-related social odor.

scientific article

Persistent sensitization of depressive-like behavior and thermogenic response during maternal separation in pre- and post-weaning guinea pigs.

scientific article published on 27 September 2011

Pharmacology of a novel central nervous system-penetrant P2X7 antagonist JNJ-42253432.

scientific article published on 30 September 2014

Play behavior in rats pretreated with scopolamine: increased play solicitation by the non-injected partner.

scientific article published on 18 October 2005

Preface: Setting the stage for understanding alcohol effects in late aging: A special issue including both human and rodent studies

scientific article published on 01 January 2019

Prior stressor exposure sensitizes LPS-induced cytokine production.

scientific article published in August 2002

Proinflammatory activity and the sensitization of depressive-like behavior during maternal separation ⬇️

scientific article published on June 1, 2011

Rapid alterations in neuroimmune gene expression after acute ethanol: Timecourse, sex differences and sensitivity to cranial surgery

scientific article published on 15 October 2019

Repeated exposure to two stressors in sequence demonstrates that corticosterone and paraventricular nucleus of the hypothalamus interleukin-1β responses habituate independently.

scientific article published on 12 August 2017

Responses of guinea pig pups during isolation in a novel environment may represent stress-induced sickness behaviors.

scientific article

Sensitization of depressive-like behavior during repeated maternal separation is associated with more-rapid increase in core body temperature and reduced plasma cortisol levels.

scientific article published on 3 November 2011

Separation, Sickness, and Depression: A New Perspective on an Old Animal Model

scientific article

Sociality and sickness: have cytokines evolved to serve social functions beyond times of pathogen exposure?

scientific article published on 31 October 2013

Stereological Analysis of Microglia in Aged Male and Female Fischer 344 Rats in Socially Relevant Brain Regions

scientific article published on 26 February 2018

Stress, alcohol and infection during early development: a brief review of common outcomes and mechanisms.

scientific article published on 22 April 2018

Stress, learned helplessness, and brain interleukin-1 beta.

scientific article

Stress-dependent changes in neuroinflammatory markers observed after common laboratory stressors are not seen following acute social defeat of the Sprague Dawley rat

scientific article published in August 2011

Stress-induced sickness behaviors: an alternative hypothesis for responses during maternal separation

scientific article published on 01 September 2001

Surgical and pharmacological suppression of glucocorticoids prevents the enhancement of morphine conditioned place preference by uncontrollable stress in rats.

scientific article published on 17 November 2004

Sustained alterations in neuroimmune gene expression after daily, but not intermittent, alcohol exposure

scientific article published on 18 May 2016

TNF-α–Induced Corticosterone Elevation But Not Serum Protein or Corticosteroid Binding Globulin Reduction Is Vagally Mediated

scientific article published on 01 January 1997

The impact of ventral noradrenergic bundle lesions on increased IL-1 in the PVN and hormonal responses to stress in male sprague dawley rats.

scientific article published on 13 May 2013

The inflamed axis: the interaction between stress, hormones, and the expression of inflammatory-related genes within key structures comprising the hypothalamic-pituitary-adrenal axis.

scientific article published on 31 October 2013

The influence of central interleukin-6 on behavioral changes associated with acute alcohol intoxication in adult male rats

scientific article published on 22 November 2018

The involvement of norepinephrine and microglia in hypothalamic and splenic IL-1beta responses to stress.

scientific article published on 4 January 2006

The role of neuroinflammation in the release of aversive odor cues from footshock-stressed rats: Implications for the neural mechanism of alarm pheromone ⬇️

scientific article published on May 1, 2011

Timecourse and corticosterone sensitivity of the brain, pituitary, and serum interleukin-1beta protein response to acute stress.

scientific article published on March 2000

Treadmill running produces both positive and negative physiological adaptations in Sprague-Dawley rats

scientific article published in October 2000

List of works by Terrence Deak

A Pivotal Role for Thiamine Deficiency in the Expression of Neuroinflammation Markers in Models of Alcohol-Related Brain Damage

A brief overview of the 2016 Neurobiology of Stress Workshop.

A cross-sectional comparison of ethanol-related cytokine expression in the hippocampus of young and aged Fischer 344 rats

A long-term increase in basal levels of corticosterone and a decrease in corticosteroid-binding globulin after acute stressor exposure

A multispecies approach for understanding neuroimmune mechanisms of stress

A users guide to HPA axis research.

A working model for the assessment of disruptions in social behavior among aged rats: The role of sex differences, social recognition, and sensorimotor processes

Acute Stress May Facilitate Recovery from a Subcutaneous Bacterial Challenge

Acute illness induces the release of aversive odor cues from adult, but not prepubertal, male rats and suppresses social investigation by conspecifics.

Acute illness-induced behavioral alterations are similar to those observed during withdrawal from acute alcohol exposure ⬇️

Acute stress imposed during adolescence has minimal effects on hypothalamic-pituitary-adrenal (HPA) axis sensitivity in adulthood in female Sprague Dawley rats

Acute stress imposed during adolescence yields heightened anxiety in Sprague Dawley rats that persists into adulthood: Sex differences and potential involvement of the Medial Amygdala

Acute stressor exposure facilitates innate immunity more in physically active than in sedentary rats.

Adolescent Ethanol Exposure Leads to Stimulus-Specific Changes in Cytokine Reactivity and Hypothalamic-Pituitary-Adrenal Axis Sensitivity in Adulthood

Adolescent forced swim stress increases social anxiety-like behaviors and alters kappa opioid receptor function in the basolateral amygdala of male rats

Adolescent forced swim stress increases social anxiety-like behaviors and alters the dynorphin/kappa opioid receptor system in the basolateral amygdala of males

Alpha-melanocyte stimulating hormone reduces putative stress-induced sickness behaviors in isolated guinea pig pups.

Analysis of c-Fos induction in response to social interaction in male and female Fisher 344 rats.

Anti-inflammatory influences on behavioral, but not cortisol, responses during maternal separation.

Assessment of Extracellular Cytokines in the Hippocampus of the Awake Behaving Rat Using Large-Molecule Microdialysis Combined with Multiplex Arrays After Acute and Chronic Ethanol Exposure

Assessment of social behavior directed toward sick partners and its relation to central cytokine expression in rats

Attractiveness of illness-associated odorant cues in female rats is modulated by ovarian hormones, but not associated with pro-inflammatory cytokine levels.

Behavioral and neurochemical effects of chronic L-DOPA treatment on nonmotor sequelae in the hemiparkinsonian rat ⬇️

Behavioral effects of peripheral corticotropin-releasing factor during maternal separation may be mediated by proinflammatory activity ⬇️

Central infusion of interleukin-1 receptor antagonist blocks the reduction in social behavior produced by prior stressor exposure.

Central neuroimmune activity and depressive-like behavior in response to repeated maternal separation and injection of LPS

Conditioned effects of ethanol on the immune system.

Contribution of the striatum to the effects of 5-HT1A receptor stimulation in L-DOPA-treated hemiparkinsonian rats

Corticosterone and progesterone differentially regulate HPA axis and neuroimmune responses to stress in male rats

Cross-species evidence for the role of interleukin-33 in depression risk

Differential effects of acute versus chronic stress on ethanol sensitivity: evidence for interactions on both behavioral and neuroimmune outcomes.

Discrimination between changes in glucocorticoid receptor expression and activation in rat brain using western blot analysis

Early Attachment Disruption, Inflammation, and Vulnerability for Depression in Rodent and Primate Models

Early attachment-figure separation and increased risk for later depression: potential mediation by proinflammatory processes.

Early ontogeny as a unique developmental epoch for learning, memory and consequences of alcohol exposure: A Festschrift to honor the work of Dr. Norman E. Spear

Effects of the estrous cycle and ovarian hormones on central expression of interleukin-1 evoked by stress in female rats

Endogenous glucocorticoids play a positive regulatory role in the anti-keyhole limpet hemocyanin in vivo antibody response.

Endogenous opioids as substrates for ethanol intake in the neonatal rat: The impact of prenatal ethanol exposure on the opioid family in the early postnatal period.

Enhancement of the hypothalamic-pituitary-adrenal axis but not cytokine responses to stress challenges imposed during withdrawal from acute alcohol exposure in Sprague-Dawley rats

Evidence that brief stress may induce the acute phase response in rats ⬇️

Exogenous corticosterone reduces L-DOPA-induced dyskinesia in the hemi-parkinsonian rat: role for interleukin-1beta.

Exposure to acute stress induces brain interleukin-1beta protein in the rat.

Exposure to forced swim stress does not alter central production of IL-1.

Factors promoting vulnerability to dysregulated stress reactivity and stress-related disease

From adolescence to late aging: A comprehensive review of social behavior, alcohol, and neuroinflammation across the lifespan

From hippocampus to dorsal horn: the pervasive impact of IL-1 on learning and memory spans the length of the neuroaxis.

From models to mechanisms: odorant communication as a key determinant of social behavior in rodents during illness-associated states.

Gene expression changes in the hypothalamus provide evidence for regionally-selective changes in IL-1 and microglial markers after acute stress

Highlight Article: Conditioning the neuroimmune response to ethanol using taste and environmental cues in adolescent and adult rats

Immune cells and cytokine circuits: toward a working model for understanding direct immune-to-adrenal communication pathways.

Impact of housing conditions on social behavior, neuroimmune markers, and oxytocin receptor expression in aged male and female Fischer 344 rats

Late aging alters behavioral sensitivity to ethanol in a sex-specific manner in Fischer 344 rats

Late aging-associated increases in L-DOPA-induced dyskinesia are accompanied by heightened neuroinflammation in the hemi-parkinsonian rat

Long-term changes in mineralocorticoid and glucocorticoid receptor occupancy following exposure to an acute stressor.

Male adolescent rats display blunted cytokine responses in the CNS after acute ethanol or lipopolysaccharide exposure

Maternal inhibition of infant behavioral response following isolation in novel surroundings and inflammatory challenge ⬇️

Maternal separation increases later immobility during forced swim in guinea pig pups: evidence for sensitization of a depressive-like state

Maternal separation produces, and a second separation enhances, core temperature and passive behavioral responses in guinea pig pups.

Naproxen attenuates sensitization of depressive-like behavior and fever during maternal separation.

Neuroendocrine and neuroimmune adaptation to Chronic Escalating Distress (CED): A novel model of chronic stress

Neuroimmune mechanisms of stress: sex differences, developmental plasticity, and implications for pharmacotherapy of stress-related disease

Novel aspects of glucocorticoid actions

On the time course, generality, and regulation of plasma progesterone release in male rats by stress exposure.

Oxytocin and vasopressin in the medial amygdala differentially modulate approach and avoidance behavior toward illness-related social odor.

Persistent sensitization of depressive-like behavior and thermogenic response during maternal separation in pre- and post-weaning guinea pigs.

Pharmacology of a novel central nervous system-penetrant P2X7 antagonist JNJ-42253432.

Play behavior in rats pretreated with scopolamine: increased play solicitation by the non-injected partner.

Preface: Setting the stage for understanding alcohol effects in late aging: A special issue including both human and rodent studies

Prior stressor exposure sensitizes LPS-induced cytokine production.

Proinflammatory activity and the sensitization of depressive-like behavior during maternal separation ⬇️

Rapid alterations in neuroimmune gene expression after acute ethanol: Timecourse, sex differences and sensitivity to cranial surgery

Repeated exposure to two stressors in sequence demonstrates that corticosterone and paraventricular nucleus of the hypothalamus interleukin-1β responses habituate independently.

Responses of guinea pig pups during isolation in a novel environment may represent stress-induced sickness behaviors.

Sensitization of depressive-like behavior during repeated maternal separation is associated with more-rapid increase in core body temperature and reduced plasma cortisol levels.

Separation, Sickness, and Depression: A New Perspective on an Old Animal Model

Sociality and sickness: have cytokines evolved to serve social functions beyond times of pathogen exposure?

Stereological Analysis of Microglia in Aged Male and Female Fischer 344 Rats in Socially Relevant Brain Regions

Stress, alcohol and infection during early development: a brief review of common outcomes and mechanisms.

Stress, learned helplessness, and brain interleukin-1 beta.