List of works - David Díez

(2R,3S,4R)-3,4-Isopropyl-idenedi-oxy-2-(phenyl-sulfonyl-meth-yl)pyrrolidin-1-ol.

scientific article published on 28 July 2012

(3R,4S)-3,4-Isopropyl-idenedioxy-3,4-dihydro-2H-pyrrole 1-oxide.

scientific article published on 13 April 2011

(3R,4S)-3,4-Isopropylidenedioxy-5-phenylsulfonylmethyl-3,4-dihydro-2H-pyrrole 1-oxide ⬇️

scientific article published on April 13, 2011

(3S,4S,E)-tert-Butyl 3,4-dibromo-5-oxo-cyclo-oct-1-ene-carboxyl-ate.

scientific article published on 23 December 2011

1,3-Dipolar cycloaddition of nitrones with phenylvinyl sulfone. An experimental and theoretical study

1-Hydroxymethyl-4-phenylsulfonybutadiene, a versatile building block for the synthesis of 2,3,4-trisusbtituted tetrahydrothiophenes.

scientific article published on 30 April 2004

A Novel Cytotoxic Conjugate Derived from the Natural Product Podophyllotoxin as a Direct-Target Protein Dual Inhibitor

scientific article published on 17 September 2020

A convenient asymmetric synthesis of a beta-amino ester with additional functionalization as a precursor for peptide nucleic acid (PNA) monomers

scientific article published on 21 June 2006

A novel strategy towards the asymmetric synthesis of orthogonally funtionalised 2-N-benzyl-N-alpha-methylbenzylamino- 5-carboxymethyl-cyclopentane-1-carboxylic acid.

scientific article published on 30 April 2004

Antibacterial Natural Halimanes: Potential Source of Novel Antibiofilm Agents

scientific article published on 08 April 2020

Antibacterial and antioxidant activity of Portuguese Lavandula luisieri (Rozeira) Rivas-Martinez and its relation with their chemical composition

scientific article (publication date: 2016)

Asymmetric synthesis of the stereoisomers of 2-amino-5-carboxymethyl-cyclopentane-1-carboxylate.

scientific article published on 5 January 2004

Biomimetic synthesis of two salmahyrtisanes: salmahyrtisol A and hippospongide A.

scientific article

Chemistry of epoxysulfones: straightforward synthesis of versatile chiral building blocks

scientific article published on 01 November 2003

Crystal structure of (2R,3aR)-2-phenyl-sulfonyl-2,3,3a,4,5,6-hexa-hydro-pyrrolo-[1,2-b]isoxazole.

scientific article published on January 2017

Crystal structure of methyl (4R)-4-(4-meth-oxy-benzo-yl)-4-{[(1R)-1-phenyl-eth-yl]carbamo-yl}butano-ate.

scientific article published on 14 March 2017

Cyclic beta-amino acid derivatives: synthesis via lithium amide promoted tandem asymmetric conjugate addition-cyclisation reactions.

scientific article published on 2 March 2005

Design, synthesis, pharmacological evaluation and molecular dynamics of β-amino acids morphan-derivatives as novel ligands for opioid receptors

scientific article published on 22 June 2015

Diastereoselective synthesis of chiral 1,3-cyclohexadienals

scientific article published on 13 February 2018

Diastereoselective synthesis of delta-aminoacids through domino Ireland-Claisen rearrangement and Michael addition

scientific article published on 10 April 2008

Domino Elimination/Nucleophilic Addition in the Synthesis of Chiral Pyrrolidines ⬇️

scientific article published on July 5, 2013

Enantioselective synthesis of cis-decalins using organocatalysis and sulfonyl Nazarov reagents

scientific article published on 10 April 2015

From labdanes to drimanes. Degradation of the side chain of dihydrozamoranic acid.

scientific article published on 30 April 2004

Halimane diterpenoids: sources, structures, nomenclature and biological activities

scientific article published on 01 September 2018

Hydrotalcite catalysis for the synthesis of new chiral building blocks

scientific article published on 9 October 2015

Marine Alkylpurines: A Promising Group of Bioactive Marine Natural Products.

scientific article

Microbial hydroxylation of sclareol by Rhizopus stolonifer.

scientific article published on 31 August 2005

Minor diterpenoids from Halimium viscosum

scientific article published on 01 January 2001

Multicomponent Domino Reaction in the Asymmetric Synthesis of Cyclopentan[c]pyran Core of Iridoid Natural Products

scientific article published on 13 March 2020

Organocatalyzed Synthesis of [3.2.1] Bicyclooctanes.

scientific article published on 28 April 2018

Phytochemical Composition of Lichen Parmotrema hypoleucinum (J. Steiner) Hale from Algeria ⬇️

scientific article published on 16 August 2022

Prenylflavonoids and prenyl/alkyl-phloroacetophenones: synthesis and antitumour biological evaluation.

scientific article published on 23 June 2010

Preparation of methyl (1R,2S,5S)- and (1S,2R,5R)-2-amino-5-tert-butyl-cyclopentane-1-carboxylates by parallel kinetic resolution of methyl (RS)-5-tert-butyl-cyclopentene-1-carboxylate.

scientific article published in October 2003

Ring-closing metathesis as key step in the synthesis of Luffarin I, 16-epi-Luffarin I and Luffarin A.

scientific article published on 20 October 2015

Sesquiterpenyl indoles

scientific article published on December 2013

Stereocontrolled synthesis of cyclopropanol amino acids from allylic sulfones: conformationally restricted building blocks

scientific article published on 01 October 2003

Synergistic antibacterial activity of the essential oil of aguaribay (Schinus molle L.).

scientific article published on 12 October 2012

Synthesis and bioactivity of Luffarin I.

scientific article published on 20 April 2015

Synthesis and biological activity of polyalthenol and pentacyclindole analogues.

scientific article published on 25 December 2013

Synthesis of (R)-2-(benzyloxy)-tetrahydro-5,5-dimethylfuran by a new oxidative rearrangement

scientific article published on 18 December 2006

Synthesis of Bioconjugate Sesterterpenoids with Phospholipids and Polyunsaturated Fatty Acids.

scientific article published on 30 December 2015

Synthesis of Luffarin L and 16-epi-Luffarin L Using a Temporary Silicon-Tethered Ring-Closing Metathesis Reaction

scientific article published on 29 May 2015

Synthesis of a new chiral pyrrolidine

scientific article published on 9 March 2010

Synthesis of an ent-halimanolide from ent-halimic acid

scientific article published on 09 May 2008

Synthesis of three marine natural sesterterpenolides from methyl isoanticopalate. First enantioselective synthesis of luffolide

scientific article published on 01 November 2005

Synthetic studies towards the ent-labdane diterpenoids: rearrangement of ent-halimanes

scientific article published on 24 October 2006

The Methylene-Cycloalkylacetate (MCA) Scaffold in Terpenyl Compounds with Potential Pharmacological Activities

scientific article published on 05 June 2019

To be or not to be butterfly: New mechanistic insights in the Aza-Michael asymmetric addition of lithium (R)-N-benzyl-N-(α-methylbenzyl)amide

scientific article published on 23 July 2014

Yamaguchi-type lactonization as a key step in the synthesis of marine metabolites: (+)-luffalactone.

scientific article

List of works by David Díez

(2R,3S,4R)-3,4-Isopropyl-idenedi-oxy-2-(phenyl-sulfonyl-meth-yl)pyrrolidin-1-ol.

(3R,4S)-3,4-Isopropyl-idenedioxy-3,4-dihydro-2H-pyrrole 1-oxide.

(3R,4S)-3,4-Isopropylidenedioxy-5-phenylsulfonylmethyl-3,4-dihydro-2H-pyrrole 1-oxide ⬇️

(3S*,4S*,E)-tert-Butyl 3,4-dibromo-5-oxo-cyclo-oct-1-ene-carboxyl-ate.

1,3-Dipolar cycloaddition of nitrones with phenylvinyl sulfone. An experimental and theoretical study

1-Hydroxymethyl-4-phenylsulfonybutadiene, a versatile building block for the synthesis of 2,3,4-trisusbtituted tetrahydrothiophenes.

A Novel Cytotoxic Conjugate Derived from the Natural Product Podophyllotoxin as a Direct-Target Protein Dual Inhibitor

A convenient asymmetric synthesis of a beta-amino ester with additional functionalization as a precursor for peptide nucleic acid (PNA) monomers

A novel strategy towards the asymmetric synthesis of orthogonally funtionalised 2-N-benzyl-N-alpha-methylbenzylamino- 5-carboxymethyl-cyclopentane-1-carboxylic acid.

Antibacterial Natural Halimanes: Potential Source of Novel Antibiofilm Agents

Antibacterial and antioxidant activity of Portuguese Lavandula luisieri (Rozeira) Rivas-Martinez and its relation with their chemical composition

Asymmetric synthesis of the stereoisomers of 2-amino-5-carboxymethyl-cyclopentane-1-carboxylate.

Biomimetic synthesis of two salmahyrtisanes: salmahyrtisol A and hippospongide A.

Chemistry of epoxysulfones: straightforward synthesis of versatile chiral building blocks

Crystal structure of (2R*,3aR*)-2-phenyl-sulfonyl-2,3,3a,4,5,6-hexa-hydro-pyrrolo-[1,2-b]isoxazole.

Crystal structure of methyl (4R)-4-(4-meth-oxy-benzo-yl)-4-{[(1R)-1-phenyl-eth-yl]carbamo-yl}butano-ate.

Cyclic beta-amino acid derivatives: synthesis via lithium amide promoted tandem asymmetric conjugate addition-cyclisation reactions.

Design, synthesis, pharmacological evaluation and molecular dynamics of β-amino acids morphan-derivatives as novel ligands for opioid receptors

Diastereoselective synthesis of chiral 1,3-cyclohexadienals

Diastereoselective synthesis of delta-aminoacids through domino Ireland-Claisen rearrangement and Michael addition

Domino Elimination/Nucleophilic Addition in the Synthesis of Chiral Pyrrolidines ⬇️

Enantioselective synthesis of cis-decalins using organocatalysis and sulfonyl Nazarov reagents

From labdanes to drimanes. Degradation of the side chain of dihydrozamoranic acid.

Halimane diterpenoids: sources, structures, nomenclature and biological activities

Hydrotalcite catalysis for the synthesis of new chiral building blocks

Marine Alkylpurines: A Promising Group of Bioactive Marine Natural Products.

Microbial hydroxylation of sclareol by Rhizopus stolonifer.

Minor diterpenoids from Halimium viscosum

Multicomponent Domino Reaction in the Asymmetric Synthesis of Cyclopentan[c]pyran Core of Iridoid Natural Products

Organocatalyzed Synthesis of [3.2.1] Bicyclooctanes.

Phytochemical Composition of Lichen Parmotrema hypoleucinum (J. Steiner) Hale from Algeria ⬇️

Prenylflavonoids and prenyl/alkyl-phloroacetophenones: synthesis and antitumour biological evaluation.

Preparation of methyl (1R,2S,5S)- and (1S,2R,5R)-2-amino-5-tert-butyl-cyclopentane-1-carboxylates by parallel kinetic resolution of methyl (RS)-5-tert-butyl-cyclopentene-1-carboxylate.

Ring-closing metathesis as key step in the synthesis of Luffarin I, 16-epi-Luffarin I and Luffarin A.

Sesquiterpenyl indoles

Stereocontrolled synthesis of cyclopropanol amino acids from allylic sulfones: conformationally restricted building blocks

Synergistic antibacterial activity of the essential oil of aguaribay (Schinus molle L.).

Synthesis and bioactivity of Luffarin I.

Synthesis and biological activity of polyalthenol and pentacyclindole analogues.

Synthesis of (R)-2-(benzyloxy)-tetrahydro-5,5-dimethylfuran by a new oxidative rearrangement

Synthesis of Bioconjugate Sesterterpenoids with Phospholipids and Polyunsaturated Fatty Acids.

Synthesis of Luffarin L and 16-epi-Luffarin L Using a Temporary Silicon-Tethered Ring-Closing Metathesis Reaction

Synthesis of a new chiral pyrrolidine

Synthesis of an ent-halimanolide from ent-halimic acid

Synthesis of three marine natural sesterterpenolides from methyl isoanticopalate. First enantioselective synthesis of luffolide

Synthetic studies towards the ent-labdane diterpenoids: rearrangement of ent-halimanes

The Methylene-Cycloalkylacetate (MCA) Scaffold in Terpenyl Compounds with Potential Pharmacological Activities

To be or not to be butterfly: New mechanistic insights in the Aza-Michael asymmetric addition of lithium (R)-N-benzyl-N-(α-methylbenzyl)amide

Yamaguchi-type lactonization as a key step in the synthesis of marine metabolites: (+)-luffalactone.

(3S,4S,E)-tert-Butyl 3,4-dibromo-5-oxo-cyclo-oct-1-ene-carboxyl-ate.

Crystal structure of (2R,3aR)-2-phenyl-sulfonyl-2,3,3a,4,5,6-hexa-hydro-pyrrolo-[1,2-b]isoxazole.