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List of works by Irina Sadovnik

A kinase profile-adapted drug combination elicits synergistic cooperative effects on leukemic cells carrying BCR-ABL1T315I in Ph+ CML

scientific article published on 28 December 2018

A new human mast cell line expressing a functional IgE receptor converts to tumorigenic growth by KIT D816V transfection

scientific article published on 27 March 2014

BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1

scientific article

Cancer stem cells in basic science and in translational oncology: can we translate into clinical application?

scientific article

Cell-based and antibody-mediated immunotherapies directed against leukemic stem cells in acute myeloid leukemia: Perspectives and open issues

scientific article published on 13 July 2020

Coronavirus Receptor Expression Profiles in Human Mast Cells, Basophils, and Eosinophils

scholarly article published on 17 January 2024

DPPIV (CD26) as a novel stem cell marker in Ph+ chronic myeloid leukaemia

scientific article

Delineation of target expression profiles in CD34+/CD38- and CD34+/CD38+ stem and progenitor cells in AML and CML

scientific article published on 01 October 2020

Dipeptidylpeptidase IV (CD26) defines leukemic stem cells (LSC) in chronic myeloid leukemia

scientific article published on 28 April 2014

Effects of Ponatinib and Other Novel TKI On Growth, Survival, and Function of Neoplastic Eosinophils Carrying FIP1L1/Pdgfra ⬇️

scholarly article

Evaluation of Cell Surface Markers and Targets in Leukemic Stem Cells (LSC) Reveals Distinct Expression Profiles, Unique Drug Effects, and Specific Checkpoint Regulation in AML LSC and CML LSC ⬇️

scholarly article

Evaluation of cooperative antileukemic effects of nilotinib and vildagliptin in Ph+ chronic myeloid leukemia

scientific article published on 12 October 2017

Expression of CD25 on leukemic stem cells in BCR-ABL1+ CML: Potential diagnostic value and functional implications.

scientific article published on 27 April 2017

FLAG-induced remission in a patient with acute mast cell leukemia (MCL) exhibiting t(7;10)(q22;q26) and KIT D816H

scientific article published on 26 November 2013

Further Evaluation of Pro-Atherogenic and Anti-Angiogenic Effects of Nilotinib in Mice and in Patients with Ph-Chromosome+ CML ⬇️

scholarly article

Identification of CD25 as STAT5-Dependent Growth Regulator of Leukemic Stem Cells in Ph+ CML.

scientific article published on 25 November 2015

Identification of Ponatinib as a potent inhibitor of growth, migration, and activation of neoplastic eosinophils carrying FIP1L1-PDGFRA

scientific article

Identification of a Neoplastic Stem Cell in Human Mast Cell Leukemia ⬇️

scholarly article

Identification of a leukemia-initiating stem cell in human mast cell leukemia

scientific article published on 05 April 2019

Identification of bromodomain-containing protein-4 as a novel marker and epigenetic target in mast cell leukemia

scientific article published on 9 June 2015

Identification of campath-1 (CD52) as novel drug target in neoplastic stem cells in 5q-patients with MDS and AML.

scientific article published on 5 May 2014

Immunotherapy-Based Targeting and Elimination of Leukemic Stem Cells in AML and CML ⬇️

scientific article published on 29 August 2019

Mast cells as a unique hematopoietic lineage and cell system: From Paul Ehrlich's visions to precision medicine concepts

scientific article published on 29 August 2020

Nilotinib and Dasatinib Produce Synergistic Growth-Inhibitory Effects In Imatinib-Resistant CML Cells, Including Subclones Bearing the Multi-Resistant BCR/ABL Mutant T315I ⬇️

scholarly article

Nilotinib-induced vasculopathy: identification of vascular endothelial cells as a primary target site.

scientific article published on 31 July 2017

Oncostatin M is a FIP1L1/PDGFRA-dependent mediator of cytokine production in chronic eosinophilic leukemia

scientific article published on 27 April 2013

Pharmacologic inhibition of STAT5 in acute myeloid leukemia

scientific article published on 2 February 2018

Phenotypic Characterization of Leukemia-Initiating Stem Cells in Chronic Myelomonocytic Leukemia (CMML) ⬇️

scholarly article

Phenotyping and Target Expression Profiling of CD34+/CD38- and CD34+/CD38+ Stem- and Progenitor cells in Acute Lymphoblastic Leukemia.

scientific article published on 15 May 2018

Proposed diagnostic criteria and classification of basophilic leukemias and related disorders

scientific article published on 16 January 2017

Quantitative assessment of the CD26+ leukemic stem cell compartment in chronic myeloid leukemia: patient-subgroups, prognostic impact, and technical aspects.

scientific article published on 29 April 2016

Redistribution, homing and organ-invasion of neoplastic stem cells in myeloid neoplasms

scientific article published on 10 August 2019

The Oncogenic Transcription Factor STAT5 Triggers Aberrant Expression Of CD25 (IL-2RA) In Neoplastic Stem Cells In Ph+ CML ⬇️

scholarly article

What are the challenges in 2016 regarding resistance to tyrosine kinase inhibitors in chronic myeloid leukemia and cancer?

scientific article published on 19 July 2016

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